Department of Molecular Parasitology
Ehime Univ Graduate School of Medicine Mol Parasitol Ishino

Tomoko ISHINO, Ph.D

Associate Professor
Tokyo University, Faculty of Pharmaceutical sciences, 1996
Tokyo University, Graduate School of Pharmaceutical sciences, Ph.D. 2001
Post Doc, Mie University, 2001-2006

Post Doc, Institut Pasteur, 2006-2009

Address Department of Molecular Parasitology
Ehime University, Graduate School of Medicine
Shitsukawa, Toon, Ehime 791-0925
Phone (+81)-89-960-5286
Fax (+81)-89-960-5287
E-mail
Scientific Interest Sporozoites Infection Mechanism of the Hepatocytes
Technique Molecular Biology, Cellular Biology
Theme :: Publications




Theme

Molecular basis of sporozoites liver infectious mechanisms

Publications

Recent Research Articles


Gueirard P, Tavares J, Thiberge S, Bernex F, Ishino T, Milon G, Franke-Fayard B, Janse CJ, Me´nard R, Amino R. Development of the malaria parasite in the skin of the mammalian host. Proc Natl Acad Sci U S A. 2010 Oct 26;107(43):18640-5.
[Abstract]

Ishino T, Boisson B, Orito Y, Lacroix C, Bischoff E, Loussert C, Janse C, Menard R, Yuda M, Baldacci P.  LISP1 is important for the egress of Plasmodium parasites from liver cells. Cell Microbiol Sep;11(9):1329-39. (2009).
[Abstract]

Amino R, Giovannini D, Thiberge S, Gueirard P, Boisson B, Dubremetz JF, Prevost MC, Ishino T, Yuda M, Menard R. Host cell traversal is important for progression of the malaria parasite through the dermis to the liver.  Cell Host Microbe. 3(2):88-96 (2008/02).
[Abstract]

Ishino T, Kunieda T, Natori S, Sekimizu K, Kubo T.Identification of novel members of the Xenopus Ca2+ -dependent lectin family and analysis of their gene expression during tail regeneration and development. J Biochem. 141(4):479-88 (2007/04).
[Abstract]

Kariu T*, Ishino T*, Yano K, Chinzei Y, Yuda M.(*: equally contributed) CelTOS, a novel malarial protein that mediates transmission to mosquito and vertebrate hosts. Mol Microbiol. 59(5):1369-79 (2006/03).
[Abstract]

Ishino T, Orito Y, Chinzei Y, Yuda M. A calcium-dependent protein kinase regulates Plasmodium ookinete access to the midgut epithelial cell.  Mol Microbiol. 59(4):1175-84 (2006/02).
[Abstract]

Ishino T, Chinzei Y, Yuda M. Two proteins with 6-cys motifs are required for malarial parasites to commit to infection of the hepatocyte.  Mol Microbiol. 58(5):1264-75 (2005/12).
[Abstract]

Ishino T, Chinzei Y, Yuda M. A Plasmodium sporozoite protein with a membrane attack complex domain is required for breaching the liver sinusoidal cell layer prior to hepatocyte infection.  Cell Microbiol. 7(2):199-208 (2005/02).
[Abstract]

Yuda M, Ishino T. Liver invasion by malarial parasites--how do malarial parasites break through the host barrier?  Cell Microbiol. 6(12):199-208 (2004/12).
[Abstract]

Kadota K, Ishino T, Matsuyama T, Chinzei Y, Yuda M. Essential role of membrane-attack protein in malarial transmission to mosquito host.  Proc Natl Acad Sci U S A. 101(46):16310-5 (2004/11).
[Abstract]

Ishino T, Yano K, Chinzei Y, Yuda M. Cell-passage activity is required for the malarial parasite to cross the liver sinusoidal cell layer.  PLoS Biol. 2(1):16310-5 (2004/01).
[Abstract]

Ishino T, Shirai M, Kunieda T, Sekimizu K, Natori S, Kubo T. Identification of genes induced in regenerating Xenopus tadpole tails by using the differential display method.  Dev Dyn. 226(2):317-25 (2003/02).
[Abstract]

Ishino T, Ohtsuki S, Homma K, Natori S. cDNA cloning of mouse prolyl endopeptidase and its involvement in DNA synthesis by Swiss 3T3 cells.  J Biochem. 123(3):540-5 (1998/03).
[Abstract]

 

 


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