小児医療を通じて未来を守る
愛媛大学小児科 ~小児医療を通じて未来を守る~

愛媛大学小児科業績集 2019

(論文・英文原著)

1. Kukida M, Mogi M, Kan-No H, Tsukuda K, Bai HY, Shan BS, Yamauchi T, Higaki A, Min LJ, Iwanami J, Okura T, Higaki J, Horiuchi M (2019)
AT2 receptor stimulation inhibits phosphate-induced vascular calcification.
Kidney Int 95: 138-148.

2. Sakakibara N, Morisada N, Nozu K, Nagatani K, Ohta T, Shimizu J, Wada T, Shima Y, Yamamura T, Minamikawa S, Fujimura J, Horinouchi T, Nagano C, Shono A, Ye MJ, Nozu Y, Nakanishi K, Iijima K (2019)
Clinical spectrum of male patients with OFD1 mutations.
J Hum Genet 64: 3-9.

3. Moritani K, Miyawaki R, Tokuda K, Ochi F, Eguchi-Ishimae M, Tauchi H, Eguchi M, Ishii E, Nagai K (2019)
Mesenchymal Stem Cell Therapy Overcomes Steroid Resistance in Severe Gastrointestinal Acute Graft-Versus-Host Disease.
Case Rep Transplant 2019:7890673.[Full text]

4. Eguchi-Ishimae M, Tezuka M, Kokeguchi T, Nagai K, Moritani K, Yonezawa S, Tauchi H, Tokuda K, Ishida Y, Ishii E, Eguchi M (2019)
Early detection of the PAX3-FOXO1 fusion gene in circulating tumor-derived DNA in a case of alveolar rhabdomyosarcoma.
Genes Chromosomes Cancer 58:521-529.[Full text]

5. Motoki T, Shimizu-Motohashi Y, Saito I, Komaki H, Ishiyama A, Aibara K, Jogamoto T, Tezuka Y, Kawabe M, Makino A, Nagatani K, Tatara K, Kuwabara K, Kikuchi C, Fukuda M, Ishii E, Eguchi M (2019)
Renal dysfunction can occur in advanced-stage Duchenne muscular dystrophy.
Muscle Nerve 61:192-197. doi: 10.1002/mus.26757.

 


 

(論文・英文症例報告)

1. Sonoda Y, Yamamura K, Ishii K, Ohkubo K, Ihara K, Sakai Y, Ohga S (2019)
A pediatric case with prostaglandin I2-associated thyrotoxicosis: Case report and the literature review.
J Clin Res Pediatr Endocrinol 11:207-210.

2. Kubota-Tanaka M, Osumi T, Miura S, Tsujimoto H, Imamura T, Nishimura A, Oki K, Nakamura K, Miyamoto S, Inoue K, Inoue M, Kamiya T, Yanagimachi M, Okano T, Mitsuiki N, Isoda T, Imai K, Kanegane H, Morio T, Kounami S, Endo M, Kato M, Takagi M (2019)
B-lymphoblastic lymphoma with the TCF3-PBX1 fusion gene.
Haematologica 104:e34-e37.

愛媛大学小児科業績集 2018

(論文・英文原著)

1. Ehl S, Astigarraga I, von Bahr Greenwood T, Hines M, Horne A, Ishii E, Janka G, Jordan MB, La Rosée P, Lehmberg K, Machowicz R, Nichols KE, Sieni E, Wang Z, Henter J-I (2018)
Recommendations for the use of etoposide-based therapy and bone marrow transplantation for treatment of HLH.
J Aller Clin Immunol 6:1508-1617.

2. Shibata H, Yasumi T, Shimodera S, Hiejima E, Izawa K, Kawai T, Shirakawa R, Wada T, Nishikomori R, Horiuchi H, Ohars O, Ishii E, Heike T (2018)
Human CTL-based functional analysis reveals the reliability of munc13-4 protein expression assay for FHL3 diagnosis.
Blood 131:2016-2025.

3. Tanaka T, Yoshioka K, Nishikomori R, Sakai H, Abe J, Yamashita Y, Hiramoto R, Morimoto A, Ishii E, Arakawa H, Kaneko U, Oshima Y, Okamoto N, Ohara O, Hata I, Shigematsu Y, Kawai T, Yasumi T, Heike T (2018)
National survey of Japanese patients with mevalonate kinase deficiency reveals distinctive genetic and clinical characteristics.
Mod Rheumatol 2:1-7.

4. Kamada M, Inui H, Kagawa T, Mineda A, Tamura T, Fujioka T, Motoki T, Hirai H, Ishii E, Minoru M (2018)
What information can change the attitude of teachers toward the human papillomavirus vaccine?
J Obstetr Gynecol Res 44:778-787.

5. Yanagisawa R, Nakazawa Y, Matsuda K, Yasumi T, Kanegane H, Ohga S, Morimoto A, Hashii Y, Imaizumi M, Okamoto Y, Saito AM, Horibe K, Ishii E (2018)
Outcomes in children with hemophagocytic lymphohistiocytosis treated using HLH-2004 protocol in Japan.
Int J hematol 109:206-213.

6. Eguchi M, Ozaki E, Yamauchi T, Ohta M, Higaki T, Masuda K, Imoto I, Ishii E, Eguchi-Ishimae M (2018)
Manifestation of recessive combined D‐2‐, L‐2‐hydroxyglutaric aciduria in combination with 22q11.2 deletion syndrome.
Am J Med Genet Part A 176:351-358.

7. Eguchi M, Yagi C, Tauchi H, Kobayashi M, Ishii E, Eguchi-Ishimae M (2018)
Exon skipping in CYBB mRNA and skewed inactivation of X chromosome cause Late-Onset chronic granulomatous disease.
Pediatr Hematol Oncol 35:341-349.

8. Nagai K, Hou L, Li L, Nguyen B, Seale T, Shirley C, Ma H, Levis M, Ghiaur G, Duffield A, Small D (2018)
Combination of ATO with FLT3 TKIs eliminates FLT3/ITD+ leukemia cells through reduced expression of FLT3.
Oncotarget 9:32885-32899.

9. Moritani K, Nagai K, Ochi F, Yonezawa S, Takemoto K, Tokuda K, Tauchi H, Eguchi-Ishimae M, Eguchi M, Ishii E (2018)
Prolonged adrenal insufficiency after high-dose glucocorticoid in infants with leukemia.
Pediatr Hematol Oncol 35:355-361.

10. Moritani K, Nakano N, Yonezawa S, Ochi F, Tauchi H, Eguchi-Ishimae M, Eguchi M, Ishii E, Nagai K (2018)
Usefulness of positron emission tomography-CT for diagnosis of primary bone marrow lymphoma in children.
Pediatr Hematol Oncol 35:125-130.

11. Noguchi Y, Tomizawa D, Hiroki H, Miyamoto S, Tezuka M, Miyawaki R, Tanaka-Kubota M, Okano T, Kobayashi C, Mitsuiki N, Aoki Y, Imai K, Kajiwara M, Kanegane H, Morio T, Takagi M (2018)
Hematopoietic cell transplantation for myeloid/NK cell precursor acute leukemia in second remission.
Clin Case Rep 6:1023-1028.

12. Kusakabe K, Kohno S, Inoue A, Seno T, Yonezawa S, Moritani K, Mizuno Y, Kurata M, Kitazawa R, Tauchi H, Watanabe H, Iwata S, Hirato J, Kunieda T(2018)
Combined morphological, immunohistochemical and genetic analyses of medulloepithelioma in the posterior cranial fossa.
Neuropathology 38:179-184.

13. Ochi F, Tauchi H, Nagai K, Moritani K, Tezuka M, Jogamoto T, Aibara K, Motoki T, Ishii E (2018)
Therapeutic Effect of Linezolid in Children With Health Care-Associated Meningitis or Ventriculitis.
Clin Pediatr 14:1672-1676.

14. Yamada K, Shiraishi H, Oki E, Ishige M, Fukao T, Hamada Y, Sakai N, Ochi F, Watanabe A, Kawakami S, Kuzume K, Watanabe K, Sameshima K, Nakamagoe K, Tamaoka A, Asahina N, Yokoshiki S, Miyakoshi T, Ono K, Oba K, Isoe T, Hayashi H, Yamaguchi S, Sato N (2018)
Open-label clinical trial of bezafibrate treatment in patients with fatty acid oxidation disorders in Japan.
Mol Genet Metab Rep 15:55-63.

15. Fukuyama N, Kurata A, Kawaguchi N, Tashiro R, Higaki T, Yokoi T, Tanabe Y, Nishiyama H, Itoh T, Kido T, Miyagawa M, Mochizuki T. (2018)
Two-Phase Contrast Injection Protocol for Pediatric Cardiac Computed Tomography in Children with Congenital Heart Disease.
Pediatr Cardiol 39:518-525.

16. Wu J, Mizusawa Y, Ohno S, Ding WG, Higaki T, Wang Q, Kohjitani H, Makiyama T, Itoh H, Toyoda F, James AF, Hancox JC, Matsuura H, Horie M.(2018)
A hERG-E1039X mutation and KCNQ1-R174C mutation produced a synergistic lesion on cardiac IKs channel in a compound LQTS family.
Sci Rep 8:3129.

17. Sumitomo N, Baba R, Doi S, Higaki T, Horigome H, Ichida F, Ishikawa H, Iwamoto M, Izumida N, Kasamaki Y, Kuga K, Mitani Y, Musha H, Nakanishi T, Yoshinaga M, Abe K, Ayusawa M, Hokosaki T, Kato T, Kato Y, Ohta K, Sawada H, Ushinohama H, Yoshiba S, Atarashi H, Hirayama A, Horie M, Nagashima M, Niwa K, Ogawa S, Okumura K, Tsutsui H. (2018)
Japanese Circulation Society and the Japanese Society of Pediatric Cardiology and Cardiac Surgery of Joint Working Guidelines for Heart Disease Screening in Schools (JCS 2016/JSPCCS 2016) – Digest Version. Circ J 82:2385-2444.

18. Hamada H, Suzuki H, Onouchi Y, Ebata R, Terai M, Fuse S, Okajima Y, Kurotobi S, Hirai K, Soga T, Ishiguchi Y, Okuma Y, Takada N, Yanai M, Sato J, Nakayashiro M, Ayusawa M, Yamamoto E, Nomura Y, Hashimura Y, Ouchi K, Masuda H, Takatsuki S, Hirono K, Ariga T, Higaki T, Otsuki A, Terauchi M, Aoyagi M, Sato T, Fujii T, Fujiwara T, Hanaoka H, Hata A, for the KAICA trial Investigators (2018)
Efficacy of primary treatment with immunoglobulin plus cyclosporine for prevention of coronary artery abnormalities in Kawasaki disease patients predicted to be at increased risk of IVIG non-response (KAICA study): a controlled, phase 3, randomised, open-label, blinded-endpoints trial.
Lancet 393:1128-1137.

19. Yamauchi T, Mogi M, Kan-no H, Shan B-S, Higaki A, Min L-J, Higaki T, Iwanami J, Ishii E, Horiuchi M (2018) Roles of Angiotensin II Type 2 Receptor in Mice with Fetal Growth Restriction. Hyper Res 41:157-164.

20. Higaki A, Mogi M, Iwanami J, Min LJ, Bai HY, Shan BS, Kukida M, Yamauchi T, Tsukuda K, Kan-No H, Ikeda S, Higaki J, Horiuchi M (2018) Beneficial Effect of Mas Receptor Deficiency on Vascular Cognitive Impairment in the Presence of Angiotensin II Type 2 Receptor. J Am Heart Assoc 7:e008121

21. Fukuyama N, Kurata A, Kawaguchi N, Tashiro R, Higaki T, Yokoi T, Tanabe Y, Nishiyama H, Itoh T, Kido T, Miyagawa M, Mochizuki T (2018)
Two-Phase Contrast Injection Protocol for Pediatric Cardiac Computed Tomography in Children with Congenital Heart Disease.
Pediatr Cardiol 39:518-525.

22. Uike K, Nagata H, Hirata Y, Yamamura K, Terashi E, Matsuura T, Morihana E, Ohkubo K, Ishii K, Sakai Y, Taguchi T, Ohga S (2018)
Effective shunt closure for pulmonary hypertension and liver dysfunction in congenital portosystemic venous shunt.
Pediatr Pulmonol 53:505-511.

23. Kojima-Ishii K, Toda N, Okubo K, Tocan V, Ohyama N, Makimura M, Matsuo T, Ochiai M, Ohga S, Ihara K (2018)
Metabolic and immunological assessment of small-for-gestational-age children during one-year treatment with growth hormone: the clinical impact of apolipoproteins.
Endocr J 65:449-459.

24. Sanefuji M, Ichimiya Y, Kaku N, Sasazuki M, Yonemoto K, Torio M, Mizuguchi S, Motomura Y, Muraoka M, Lee S, Baba H, Ohkubo K, Sonoda Y, Ishizaki Y, Sakai Y, Ohga S (2018)
Vascular pathomechanism in acute encephalopathy with biphasic seizures and late reduced diffusion.
J Neurol Sci 395:141-146.

25. Okamoto K, Fukuda M, Saito I, Horiuchi I, Okazawa T, Ishii E (2018)
Incidence of childhood epilepsy: A population-based study in rural Japan.
Brain & Develop 40:904-908.

26. Okamoto K, Fukuda M, Saito I, Urate R, Maniwa S, Usui D, Motoki T, Jogamoto T, Aibara K, Hosokawa T, Konishi Y, Arakawa R, Mori K, Ishii E, Saito K, Nishio H (2019)
Incidence of infantile spinal muscular atrophy on Shikoku Island of Japan.
Brain & Develop 41:36-42.

27. Kuwabara Y, Kobayashi T, D’Alessandro-Gabazza CN, Toda M, Yasuma T, Nishihama K, Takeshita A, Fujimoto H, Nagao M, Fujisawa T, Gabazza EC (2018)
Role of matrix metalloproteinase-2 in eosinophil-mediated airway remodeling.
Frontiers in Immunol 9:2163.

28. Abe T (2018)
Treatment of infants with refractory virus-associated hemophagocytic syndrome by plasma exchange.
J Kochi Medical Association 23:216-223.

29. Unzaki A, Morisada N, Nozu K, Ye MJ, Ito S, Matsunaga T, Ishikura K, Ina S, Nagatani K, Okamoto T, Inaba Y, Ito N, Igarashi T, Kanda S, Ito K, Omune K, Iwaki T, Ueno K, Yahata M, Ohtsuka Y, Nishi E, Takahashi N, Ishikawa T, Goto S, Okamoto N, Iijima K (2018) Clinically diverse phenotypes and genotypes of patients with branchio-oto-renal syndrome. J Hum Genet 63: 647-656.

30. Kamae C, Imai K, Kato T, Okano T, Honma K, Nakagawa N, Yeh TW, Noguchi E, Ohara A, Shigemura T, Takahashi H, Takakura S, Hayashi M, Honma A, Watanabe S, Shigemori T, Ohara O, Sasaki H, Kubota T, Morio T, Kanegane H, Nonoyama S (2018)
Clinical and Immunological Characterization of ICF Syndrome in Japan.
J Clin Immunol 38:927-937.

31. Ishida Y, Maeda M, Adachi S, et al (2018)
Secondary bone/soft tissue sarcoma in childhood cancer survivors: a nationwide hospital-based case-series study in Japan.
Jpn J Clin Oncol 48:806-814.

32. Ishida Y, Maeda M, Adachi S, Inada H, Kawaguchi H, Hori H, Ogawa A, Kudo K, Kiyotani C, Shichino H, Rikiishi T, Kobayashi R, Sato M, Okamura J, Goto H, Manabe A, Yoshinaga S, Qiu D, Fujimoto J, Kuroda T (2018)
Secondary cancer after a childhood cancer diagnosis: viewpoints considering primary cancer.
Int J Clin Oncol 23:1178-1188.

33. Ishida Y, Tezuka M, Hayashi M, Inoue T (2018)
Japanese childhood cancer survivors’ readiness for care as adults: a cross-sectional survey using the Transition Scales.
Psychooncology 26:1019-1026.

34. Imamura T, Taga T, Takagi M, Kawasaki H, Koh K, Taki T, Adachi S, Manabe A, Ishida Y (2018)
Nationwide survey of therapy-related leukemia in childhood in Japan.
Int J Hematol 108:91-97.

35. Sato I, Higuchi A, Yanagisawa T, Murayama S, Kumabe T, Sugiyama K, Mukasa A, Saito N, Sawamura Y, Terasaki M, Shibui S, Takahashi J, Nishikawa R, Ishida Y, K Kamibeppu (2018)
Employment status and termination among survivors of pediatrbrain tumors: a cross-sectional survey.
Int J Clin Oncol 23: 801-811.

36. Sekiguchi K, Akahane K, Ogita M, Haga C, Ito R, Arai S, Ishida Y, Tsukada Y, Kawamori J. (2018)
Efficacy of heparinoid moisturizer as a prophylactic agent for radiation dermatitis following radiotherapy after breast-conserving surgery: a randomized controlled trial.
Jpn J Clin Oncol 48:450-457.

37. Emily S. Tonorezos, Barnea Dana, Cohn R, Cypriano M, Fresneau B, Haupt R, Hjorth L, Ishida Y, Kruseova, J,.Kuehni CE, Langer T, Nathan P, Skeen J, Skinner R, Tacylidiz N, van den Heuvel-Eibrink MM, Winther JF, Hudson MM., Kevin C. Oeffinger (2018)
Models of Care for Childhood Cancer Survivors from Across the Globe: Advancing Survivorship Care in the Next Decade.
J Clin Oncol 36:2223-2230.

38. Urayama KY, Takagi M, Kawaguchi T, Matsuo K, Tanaka Y, Ayukawa Y, Arakawa Y, Hasegawa D, Yuza Y, Kaneko T, Noguchi Y, Taneyama Y, Ota S, Inukai T, Yanagimachi M, Keino D, Koike K, Toyama D, Nakazawa Y, Kurosawa H, Nakamura K, Moriwaki K, Goto H, Sekinaka Y, Morita D, Kato M, Takita J, Tanaka T, Inazawa J, Koh K, Ishida Y, Ohara A, Mizutani S, Matsuda F, Manabe A (2018)
Regional evaluation of childhood acute lymphoblastic leukemia genetic susceptibility loci among Japanese.
Sci Rep 8:789.

39. Wada Y, Kikuchi A, Arai-Ichinoi N, Sakamoto O, Takezawa Y, Iwasawa S, Niihori T, Nyuzuki H, Nakajima Y, Ogawa E, Ishige M, Hirai H, Sasai H, Fujiki R, Shirota M, Funayama R, Yamamoto M, Ito T, Ohara O, Nakayama K, Aoki Y, Koshiba S, Fukao T, Kure S (2018)
Biallelic GALM pathogenic variants cause a novel type of galactosemia.
Genet Med 21:1286-1294.

 


 

(論文・英文症例報告)

1. Ochi F, Tauchi H, Nagai K, Moritani K, Ishii E (2018)
Pseudomonas oryzihabitans bacteremia in a child with peripheral T-cell lymphoma.
Pediatr Int 60:486-488.

2. Ochi F, Tauchi H, Jogamoto T, Miura H, Moritani T, Nagai K, Ishii E (2018) 
Sepsis and pleural empyema caused by Streptococcus pyogenes after influenza A virus infection. 
Case Reports in Pediatrics 2018:4509847.[Full text]

3. Kusakabe K, Kohno S, Inoue A, Seno T, Yonezawa S, Moritani K, Mizuno Y, Kurata M, Kitazawa R, Tauchi H, Watanabe H, Iwata S, Hirato J, Kunieda T (2018)
Combined morphological, immunohistochemical and genetic analyses of medulloepithelioma in the posterior cranial fossa.
Neuropathology 38:179-184.

4. Tocan V, Ohkubo K, Higashi K, Toda N, Kojima-Ishii K, Nishiyama K, Ishimura M, Takada H, Sakamoto O, Sasaki F, Yoshimura K, Hirose S, Ohga S (2018)
Reappraising newborn screening for cobalamin C disorder.
Pediatr Neonatol 59:415-417.

5. Akamine S, Ishizaki Y, Sakai Y, Torisu H, Fukai R, Miyake N, Ohkubo K, Koga H, Sanefuji M, Sakata A, Kimura M, Yamaguchi S, Sakamoto O, Hara T, Saitsu H, Matsumoto N, Ohga S (2018)
A male case with CDKL5-associated encephalopathy manifesting transient methylmalonic acidemia.
Eur J Med Genet 61:451-454.

6. Oda F, Murakami M, Hanakawa Y, Tohyama M, Nakano N, Nishikomori R, Kambe N, Sayama K (2017)
A sporadic case of granulomatous disease negative for NOD2 mutations and mimicking Blau syndrome.
Clinical and Exp Derm 43:57-58.

7. Tanaka-Kubota M, Shinozaki K, Miyamoto S, Yanagimachi M, Okano T, Mitsuiki N, Ueki M, Yamada M, Imai K, Takagi M, Agematsu K, Kanegane H, Morio T (2018)
Hematopoietic stem cell transplantation for pulmonary alveolar proteinosis associated with primary immunodeficiency disease.
Int J Hematol 107:610-614.

9. Noguchi Y, Tomizawa D, Hiroki H, Miyamoto S, Tezuka M, Miyawaki R, Tanaka-Kubota M, Okano T, Kobayashi C, Mitsuiki N, Aoki Y, Imai K, Kajiwara M, Kanegane H, Morio T, Takagi M (2018)
Hematopoietic cell transplantation for myeloid/NK cell precursor acute leukemia in second remission.
Clin Case Rep 6:1023-1028.

10. Kuwabara K, Kawarai T, Ishida Y, Miyamoto R, Oki R, Orlacchio A, Nomura Y, Fukuda M, Ishii E, Shintaku H, Kaji R (2018)
A novel compound heterozygous TH mutation in a Japanese case of dopa-responsive dystonia with mild clinical course.
Parkinsonism & Related Disorders 46:87-89.

11. Akamatsu A, Hayashi M, Nagatani K, Goamada M (2018)
A case of severe refractory nephrotic syndrome which achieved complete remission in the wake of LDL apheresis treatment.
南予医学雑誌

 


(原著・和文)
1. 田代良、檜垣高史、髙田秀実、宮田豐壽、八木悠一郎、小川春樹、浦田啓陽、伊藤敏恭、渡部竜助、髙橋昌志、森谷友造、太田雅明、石井榮一 (2018) 学校心臓検診に心臓超音波検査を導入することによる、学童の突然死予防への有用性の検討 – あいなんハートプロジェクト –、愛媛医学 (In press)

2. 西村幸士、日野ひとみ、竹本幸司、大藤佳子、楠目和代、檜垣高史、石井榮一(2018)愛媛県東予東部地区における医療圏域を越えた広域小児二次救急輪番体制の構築.日本小児科学会雑誌122: 793-799

3. 越智史博、田内久道、石井榮一 (2018) BCGワクチン接種後乳児における核酸増幅法検査のピットフォール. 小児感染免疫 29: 311-314

4. 越智史博、田内久道、手束真理、永井功造、森谷京子、石井榮一 (2018) 骨原発腫瘍と鑑別を要したメチシリン感受性黄色ブドウ球菌による肋骨骨髄炎の1小児例. 小児科臨床 71:1571-1578

5. 浦田啓陽、手塚優子、越智史博、宮田豊寿、石井榮一 (2018) Yersinia psedotuberculosis感染とアセトアミノフェンによると考えられる急性尿細管間質性腎炎の1小児例. 日本小児腎不全学会雑誌 38: 221-225

6. 宮本仁志、鈴木崇、村上忍、越智史博、末盛浩一郎、田内久道 (2018) Exfoliative toxin,Panton-Valentine Leukocidin 産生メチシリン耐性黄色ブドウ球菌臨床分離株における毒素産生とPOT 型の関連性について. 感染症誌 92: 663-9

7. 岩橋円香、徳田桐子、手束真理、石田也寸志 (2019) 再寛解導入療法中に肺動脈血栓症を発症した急性リンパ性白血病例. 日本小児血液・がん学会雑誌 56:46-49

8. 武井美貴子、古本哲朗、苛原誠、阿部孝典、坂本恵子、山内英雄、西山謹吾、吉本啓一郎 (2018) 自殺目的にジフェンヒドラミンを過量服用し、注意欠如多動性障害と診断された思春期女児例.高知県医師会医学雑誌 23, 262-267

9. 林正俊 (2018) 勤務医として40年、子どもたちを診てきて感じること. 愛媛県医師会報 899: 16-17

10. 石田也寸志、前田美穂、岡村純、他(2018)小児がん診断後の二次性甲状腺がん:15 病院のケースシリーズ研究.日本小児血液・がん学会雑誌 55:261-268

11. 石田也寸志、佐藤伊織、井上雅美、他(2018)本邦の自家/同種造血幹細胞移植後長期生存小児患者におけるQuality of Lifeに関する横断研究.日本造血細胞移植学会雑誌 7:107-112

12. 森美智子、石田也寸志、白畑範子、奥山朝子(2018)小児がんを含むがん診療に関するNurse Practitioner(NP) の教育到達目標―日本の医師・看護師と米国NP との比較―. 日本小児血液・がん学会雑誌 55:187-193

13. 入江亘、長谷川大輔、神谷尚宏、吉川久美子、永瀬恭子、関冨晶子、天野こころ、石井里奈、芹澤裕子、坂本代喜江、大野尚子、菅家美和 、田村妙子、真部淳、石田也寸志、平田美佳、細谷亮太(2018)小児病棟に入院する小児がんの子どもの生活に対する家族の意識調査. 日本小児血液・がん学会雑誌 55:7-14

14. 山本英一、長村敏生、伊藤陽里、市川光太郎、田村卓也、村田祐二、窪田満、平本龍吾、小山典久、木崎善郎、神園淳司、井上信明、浮山超史、佐藤厚夫、種市尋宙、岡田広、清澤伸幸(2018)日本小児救急医学会調査研究員会委員会報告 第3報 化膿性髄膜炎症例のまとめ~小児救急重篤疾患登録調査(Japan Registry System for Children with critical disease;JRSC):日本小児救急医学会雑誌17: 570-571

15. 丸山なつき、苔口知樹、山本英一、石田也寸志、山内健 (2018) 発症後早期に経腸栄養を開始した小児急性膵炎の1例. 日本小児救急医学会雑誌. 17:60-63.

16. 安井沙耶、中野威史、山本英一、宇都宮秀和、石田也寸志、中野直子 (2018) 亜急性期に関節炎を合併しリウマチ性疾患との鑑別を要した川崎病2例. Progress in Medicine. 38:695-699

17. 新野亮治、片岡優子、津下充 (2018) 交通事故を契機に発症した外傷性乳び胸に対してオクトレオチドを投与した幼児例. 日本小児科学会雑誌 122(7)

18. 矢島知里, 浦田啓陽, 岩田はるか, 渡部竜助, 山内俊史, 森谷友造, 太田雅明, 檜垣高史, 石井榮一(2018)胎児期に巨大膀胱を認めた馬尾退行症候群の一例.日本周産期・新生児医学会雑誌54: 1105-1109

愛媛大学小児科業績2017

1. Bergsten E, Horne AC, Arico M, Astigarraga I, Egeler MR, Filipovich AH, Ishii E, Janka GE, Ladisch S, Lehmberg K, McClain KL, Minkov M, Montgomery S, Nanduri V, Rosso DA, Henter J-I (2017)Confirmed efficacy of etoposide and dexamethasone in HLH treatment: Long term results of the cooperative HLH-2004 study.Blood 130:2728-2738.

2. Kamada M, Inui H, Kagawa T, Mineda A, Tamura T, Fujioka T, Motoki T, Hirai H, Ishii E, Minoru M (2018)What information can change the attitude of teachers toward the human papillomavirus vaccine? J Obstetr Gynecol Res 44:778-787.

3. Eguchi M, Ozaki E, Yamauchi T, Ohta M, Higaki T, Masuda K, Imoto I, Ishii E, Eguchi-Ishimae M. (2018) Manifestation of recessive combined D‐2‐, L‐2‐hydroxyglutaric aciduria in combination with 22q11.2 deletion syndrome. Am J Med Genet Part A 176:351-358.

4. Shimada H, Kiyokawa N, Miharu M, Tanizawa A, Kurosawa H, Watanabe A, Ito M, Tono C, Yuza Y, Muramatsu H, Hotta N, Okada M, Hamamoto K, Kajiwara R, Saito AM, Horibe K, Mizutani S, Adachi S, Ishii E, Shimada H (2017) Flow cytometric analysis as an additional predictive tool of treatment response in children with chronic-phase CML treated with imatinib.Pediatr Blood Cancer 64:e26478.

5. Muramatsu H, Okuno Y, Yoshida K, Shiraishi Y, Doisaki S, Narita A,Sakaguchi H, Kawashima N, Wang X, Xu Y, Chiba K, Tanaka H, Hama A, Sanada M, Takahashi Y, Kanno H, Yamaguchi H, Ohga S, Manabe A, Harigae H, Kunishima S, Ishii E, Kobayashi M, Koike K, Watanabe K, Ito E, Takata M, Yabe M, Ogawa S, Miyano M, Kojima S (2017) Clinical application of Capture-based Targeted Sequencing for Inherited Bone Marrow Failure Syndromes. Genet Med 19: 796-802.

6. Hori M, Yasumi T, Shimodera S, Shibata H, Hiejima E, Oda H, Izawa K, Kawai T, Ishimura M, Nakano N, Shirakawa R, Nishikomori R, Takada H, Morita S, Horiuchi H , Ohara O, Ishii E, Heike T (2017) A CD57+ CTL degranulation assay effectively identifies familial hemophagocytic lymphohistiocytosis type 3 patients. J Clin Immunol 37: 92-99.

7. Takashima T, Okamura M, Yeh T, Okano T, Yamashita M, Tanaka K, Hoshino A, Mitsuiki N, Takagi M, Ishii E, Imai K, Kanegane H, Morio T (2017) Multicolor flow cytometry for the diagnosis of primary immunodeficiency diseases. J Clin Immunol 37: 486-495.

8. Kodama Y, Manabe A, Kawasaki H, Kato I, Kato K, Sato A, Matsumoto K, Kato, M, Hiramatsu H, Sano H, Kaneko T, Oda M, Saito AM, Adachi S, Horibe K, Mizutani S, Ishii E, Shimada H (2017) Salvage therapy for children with relapsed or refractory Philadelphia chromosome-positive acute lymphoblastic leukemia. Pediatr Blood Cancer 64:e26423.

9. Poitras JL, Heiser D, Li L, Nguyen B, Nagai K, Duffield AS, Gamper C, Small D. (2016)Dnmt3a deletion cooperates with the Flt3/ITD mutation to drive leukemogenesis in a murine model. Oncotarget 7: 69124-69135.

10. Ichimura T, Yoshida K, Okuno Y, Yujiri T, Nagai K, Nishi M, Shiraishi Y, Ueno H, Toki T, Chiba K, Tanaka H, Muramatsu H, Hara T, Kanno H, Kojima S, Miyano S, Ito E, Ogawa S, Ohga S (2017) Diagnostic challenge of Diamond-Blackfan anemia in mothers and children by whole-exome sequencing. Int J Hematol 105: 515-520.

11. Kusakabe K, Kohno S, Inoue A, Seno T, Yonezawa S, Moritani K, Mizuno Y, Kurata M, Kitazawa R, Tauchi H, Watanabe H, Iwata S, Hirato J, Kunieda T(2018)Combined morphological, immunohistochemical and genetic analyses of medulloepithelioma in the posterior cranial fossa. Neuropathology 38:179-184.

12. Yamauchi T, Mogi M, Kan-no H, Shan B-S, Higaki A, Min L-J, Higaki T, Iwanami J, Ishii E, Horiuchi M (2018) Roles of Angiotensin II Type 2 Receptor in Mice with Fetal Growth Restriction.Hyper Res 41:157-164.

13. Bai HY, Mogi M, Nakaoka H, Kan-No H, Tsukuda K, Wang XL, Shan BS, Kukida M, Yamauchi T, Higaki A, Min LJ, Iwanami J, Horiuchi M (2017) Synergistic Inhibitory Effect of Rosuvastatin and Angiotensin II Type 2 Receptor Agonist on Vascular Remodeling. J Pharmacol Exp Ther. 358: 352-358.

14. Fukuyama N, Kurata A, Kawaguchi N, Tashiro R, Higaki T, Yokoi T, Tanabe Y, Nishiyama H, Itoh T, Kido T, Miyagawa M, Mochizuki T (2018) Two-Phase Contrast Injection Protocol for Pediatric Cardiac Computed Tomography in Children with Congenital Heart Disease. Pediatr Cardiol 39:518-525.

15. Ito M, Takahashi H, Yano H, Shimizu YI, Yano Y, Ishizaki Y, Tanaka J, Ishii E, Fukuda M (2017) High mobility group box 1 enhances hyperthermia-induced seizures and secondary epilepsy associated with prolonged hyperthermia-induced seizures in developing rats.Metab Brain Dis 32: 2095-2104.

16. Yano Y, Yano H, Takahashi H, Yoshimoto K, Tsuda S, Fujiyama K, Shimizu Y, Motoie R, Ito M, Tanaka J, Ishii E, Fukuda M (2017) Goreisan inhibits up-regulation of Aquaporin4 and formation of cerebral edema in the rat model of juvenile hypoxic-ischemic encephalopathy. Evid Based Complement Alternat Med Article ID 3209219.

17. Jogamoto T, Yamamoto Y, Fukuda M, Suzuki Y, Imai K, Takahashi Y, Inoue Y, Ohtsuka Y. (2017) Add-on stiripentol elevates serum valproate levels in patients with or without concomitant topiramate therapy. Epilepsy Res 130, 7-12.

18. Ihara K, Toda N, Fukano C, Ayabe T, Fukami M, Ogata T, Kawamura T, Urakami T, Kikuchi N, Yokota I, Takemoto K, Mukai T, Nishii A, Kikuchi T, Mori T, Shimura N, Sasaki G, Kizu R, Takubo N, Soneda S, Fujisawa T, Takaya R, Kizaki Z, Kanzaki S, Hanaki K, Matsuura N, Kasahara Y, Kosaka K, Takahashi T, Minamitani K, Matsuo S, Mochizuki H, Kobayashi K, Koike A, Horikawa R, Teno S, Tsubouchi K, Mochizuki T, Igarashi Y, Amemiya S and Sugihara S (2017) FUT2 Nonsecretor Status Links Type 1 Diabetes Susceptibility in Japanese children. Diabet Med 34: 586-589.

19. Nakano N, Mori M, Umebayashi H, Iwata N, Kobayashi N, Masunaga K, Imagawa T, Murata T, Kinjo N, Nagai K, Miyoshi M, Takei S, Yokota S, Ishii E (2017) Characterustics and outcome of intractable vasculitis syndrome in children: nationwide survey in Japan. Mod Rheumatol. 8: 1-6.

20. Kaneko N, Iwasaki T, Ito Y, Takeda H, Morikawa S, Nakano N, Kurata M, Masumoto J (2017) Applications of reconstituted inflammasomes in a cell-free system to drug discovery and elucidation of the pathogenesis of autoinflammatory disases. Inflammation and Regeneration 37;9 DOI 10.1186

21. Shinohara M, Matsumoto K (2017) Fetal Tobacco Smoke Exposure in the Third Trimester of Pregnancy Is Associated with Atopic Eczema/Dermatitis Syndrome in Infancy.Pediatr Allergy Immunol Pulmonol 30: 155-162.

22. Ishida Y, Tezuka M, Hayashi M, Inoue F (2017)Japanese childhood cancer survivors’ readiness for care as adults: a cross-sectional survey using the Transition Scales.Psychooncology 26: 1019-1026.

23. Daida A, Yoshihara H, Inai, I, Hasegawa D, Ishida Y, Urayama KY., Manabe A (2016)Risk factors for hospital-acquired Clostridium difficile infection among pediatric patients with cancer.J Pediatr Hematol Oncol 39: e167-e172.

24. Korematsu S, Fujitaka M, Ogata M, Zaitsu M, Motomura C, Kuzume K, Toku Y, Ikeda M, Odajima H (2017) Administration of the adrenaline auto-injector at the nursery/kindergarten/school in Western Japan. Asia Pac Allergy 7: 37-41.

25. Shima H, Kiyokawa N, Miharu M, Tanizawa A, Kurosawa H, Watanabe A, Ito M, Tono C, Yuza Y, Muramatsu H, Hotta N, Okada M, Hamamoto K, Kajiwara R, Saito AM, Horibe K, Mizutani S, Adachi S, Ishii E, Shimada H (2017) Flow cytometric analysis as an additional predictive tool of treatment response in children with chronic-phase CML treated with imatinib. Pediatr Blood Cancer 64:.e26478.

26. Kodama Y, Manabe A, Kawasaki H, Kato I, Kato K, Sato A, Matsumoto K, Kato, M, Hiramatsu H, Sano H, Kaneko T, Oda M, Saito AM, Adachi S, Horibe K, Mizutani S, Ishii E, Shimada H (2017) Salvage therapy for children with relapsed or refractory Philadelphia chromosome-positive acute lymphoblastic leukemia. Pediatr Blood Cancer 64: e26423.

________________________________________

(論文・英文症例報告)
1. Chijimatsu I, Imanaka Y, Tomizawa D, Eguchi M, Nishimura S, Karakawa S, Miki M, Hamamoto K, Fujita N. (2017) Azacitidine successfully maintained the second remission in an infant with KMT2A-rearranged acute lymphoblastic leukemia who relapsed after unrelated cord blood transplantation. Pediatr Blood Cancer 64:e26697.

2. Uemura S, Tamura A, Saito A, Hasegawa D, Nino N, Yokoi T, Tahara T, Kozaki A, Kishimoto K, Ishida T, Kawasaki K, Mori T, Nishimura N, Ishimae M, Eguchi M, Kosaka Y (2017) Reemergence of translocation t (11;19)(q23;p13.1) in the absence of clinically overt leukemia. Int J Hematol 106:847-851.

3. Tezuka Y, Fukuda M, Watanabe S, Nakano T, Okamoto K, Kuzume K, Yano Y, Eguchi M, Ishimae M, Ishii E, Miyazaki T (2017) Histological characterisation of visceral changes in a patient with type 2 Gaucher disease treated with enzyme replacement therapy.Blood Cells Mol Dis 68:194-199.

4. Hino K, Fukuda M, Morino T, Ogata T, Ito M, Ishii E (2017) Spinal fusion in a patient with Fukuyama congenital muscular dystrophy. Brain Dev 39:613-619.

5. Ito M, Fukuda M, Suzuki Y, Wakamoto H, Ishii E (2017) Carnitine-related hypoglycemia caused by 3 days of pivalate antibiotic therapy in a patient with severe muscular dystrophy: A case report. BMC Pediatrics 17: 73

6. Ochi F, Tauchi H, Moritani K, Yonezawa S, Miyamoto H, Suemori K, Ishii E (2017) Rothia mucilaginosa infection in a child with acute lymphoblastic leukemia: a case report. Pediatr Blood Cancer 64: 205-206

7. Ochi F, Tauchi H, Mizumoto M, Miyamoto H, Ishii E (2017) Kluyvera ascorbata infection in a neonate.Pediatr Int 59: 640-641.

8. Ochi F, Furuno K, Chong FP, Tezuka J, Mizuno Y, Aoki T, Ishii E (2017) Bilateral hydronephrosis due to obstructive ureteral stone associated with norovirus gastroenteritis. Clin Case Reports 5:936-938.

9. Kojima A, Shikata F, Okamura T, Higaki T, Ohno S, Horie M, Uchita S, Kawanishi Y, Namiguchi K, Yasugi T, Izutani H(2017 Refractory ventricular fibrillations after surgical repair of atrial septal defects in a patient with CACNA1C gene mutations – Case report. J Cardiothoracic Surg 12:118 DOI 10.1186

10. Oda F, Murakami M, Hanakawa Y, Tohyama M, Nakano N, Nishikomori R, Kambe N, Sayama K (2018) A sporadic case of granulomatous disease negative for NOD2 mutations and mimicking Blau syndrome. Clinical and Exp Derm 43:57-58.

11. Hirai H, Hamada J, Hasegawa K, Ishii E (2017) Acanthosis nigricans in a Japanese boy with hypochondroplasia due to a K650T mutation in FGFR3. Clin Pediatr Endocrinol 26:223-228.

12. Tanaka-Kubota M, Kanegane K, Morio T (2018) Hematopoietic stem cell transplantation for pulmonary alveolar proteinosis associated with primary immunodeficiency disease. Int J Hematol 5:610-614.

13. Kuwabara K, Kawarai T, Ishida Y, Miyamoto R, Oki R, Orlacchio A, Nomura Y, Fukuda M, Ishii E, Shintaku H, Kaji R (2017) A novel compound heterozygous TH mutation in a Japanese case of dopa-responsive dystonia with mild clinical course. Parkinsonism & Related Disorders 644:48-54.
________________________________________

(和文 原著・和文)
1. 西村幸士、日野ひとみ、竹本幸司、大藤佳子、楠目和代、檜垣高史、石井榮一(2018)愛媛県東予東部地区における医療圏域を越えた広域小児二次救急輪番体制の構築.日本小児科学会雑誌 122:793-799

2. 矢島知里、濱田淳平、中矢隆大、平井洋生、竹本幸司、藤澤由樹、石井榮一 (2017) 低身長精査時の軽度空腹時高血糖を契機に診断し得た MODY 2 姉妹例.愛媛医学 36: 36-40

3. 宮本真知子、手束真理、小泉宗光、山本英一、石田也寸志、石井榮一 (2017) 呼吸不全のため心肺蘇生を要したヒトメタニューモウイルス肺炎の乳児例-当院入院症例の検討.愛媛医学 36: 52-56

4. 渡邊あさみ、徳田桐子、楠目和代、福田光成、中村和幸、加藤光弘、石井榮一(2017)新たなDCX遺伝子ミスセンス変異を認めた滑脳症の男児例.愛媛医学 36: 167-170

5. 岩本麻友美、手束真理、杉田敦郎、河上早苗、宮脇零士、米澤早知子、城賀本 敏宏、桑原こずえ、小泉宗光、中野威史、山本英一、石井榮一、石田也寸志 (2017)Imatinib併用化学療法治療中に敗血症性ショックと急性呼吸窮迫症候群を合併したフィラデルフィア染色体陽性急性リンパ性白血病の1例. 日本小児血液・がん学会雑誌 54: 15-20

6. 宮本真知子、小西恭子、山本英一、中野威史、高橋由博、石田也寸志、檜垣高史、石井榮一 (2017) 肺炎+発疹のみで冠動脈瘤を来した不全型川崎病の4ヵ月男児例.Progress in Medicine 37: 805-809

7. 越智史博, 田内久道, 石井榮一 (2018)BCGワクチン接種後乳児における核酸増幅法検査のピットフォール. 小児感染免疫 29:311-315

8. 岡田恵子、森口直彦、畠山直樹、今井剛、大曽根眞也、篠田邦大、伊藤剛、田内 久道、三木瑞香、原純一、西村真一郎 (2017) 小児の好中球減少期発熱患者におけるミカファンギンの薬物動態と安全性 小児白血病研究会(JACLS)からの報告.日本小児血液・がん学会雑誌 53:117-122

9. 石田也寸志、手束真理、林三枝、井上富美子 (2017) 小児がん経験者の成人医療移行への準備状況に関する横断的実態調査. 日本小児血液・がん学会雑誌 53: 436-447

10. 桑原優、楠目和代 (2016) NA-623NRにおける呼気一酸化窒素濃度オンライン測定とオフライン測定の比較とオフライン測定の時間的安定性に関する検討. 日本小児呼吸器学会雑誌 27: 123-129

11. 山根淳文、岩本麻友美、岡本典子、渡部竜助、髙田秀実、長谷幸治、林正俊、竹本幸司、戒能幸一 (2017) 分娩外傷を伴わない下垂体茎断裂症候群による成長ホルモン分泌不全性低身長症の1例.愛媛医学36: 95-99

12. 吉田安友子、竹本幸司、勢井友香、桑原こずえ、中野威史、山本英一、石田也寸志 (2017) 中枢性思春期早発症の合併が疑われたが, mini-pubertyと診断したソトス症候群の1例.愛媛医学 36:238-243

13. 越智史博、水野由美、青木知信 (2017)血液培養陽性となった黄色ブドウ球菌感染症の臨床像. 小児感染免疫 28: 249-256.

14. 坪谷尚季、長尾みづほ、亀田桂子、鈴木尚文、桑原優、貝沼圭吾、藤澤隆夫.(2017)小麦アレルギー患児における大麦アレルギー合併を予測する因子の検討.日本小児アレルギー学会誌 31:683-691

15. 長尾みづほ、桑原優、平山淳也、貝沼圭吾、藤澤隆夫 (2017)特異的IgE抗体の多項目同時測定システムを応用した小児アレルギー疾患の感作パターン解析 マストイムノシステムズの新しい利用法. 日本小児アレルギー学会誌31: 253-261.

16. 苔口知樹、神薗淳司、志村紀彰、松島卓哉、山根浩昌、今村徳夫、石橋紳作、天本正乃、市川光太郎 (2017) 寛解導入療法中に脳性塩類喪失症候群をきたした急性リンパ性白血病の10歳男児.日本小児救急医学会雑誌16: 39-42

17. 林正俊 (2017)市立宇和島病院小児科の患者の動きからみえる地域の抱える問題.日本小児科医会報 54: 176-179

18. 林正俊 (2107)市立宇和島病院のランチョンと教育研修.南予医学雑誌18(1)

愛媛大学小児科業績 2016

【論文・英文原著】

1. Muramatsu H, Okuno Y, Yoshida K, Shiraishi Y, Doisaki S, Narita A,Sakaguchi H, Kawashima N, Wang X, Xu Y, Chiba K, Tanaka H, Hama A, Sanada M, Takahashi Y, Kanno H, Yamaguchi H, Ohga S, Manabe A, Harigae H, Kunishima S, Ishii E, Kobayashi M, Koike K, Watanabe K, Ito E, Takata M, Yabe M, Ogawa S, Miyano M, Kojima S (2016) Clinical utility of next-generation sequencing for inherited bone marrow failure syndromes.Genet Med (in press)

2. Umeda K, Adachi S, Horikoshi Y, Imai K, Terui K, Endo M, Mitsui T, Kato K, Koh K, Kajiwara R, Ito R, Otsuka Y, Inoue M, Ishii E, Yabe H (2016) Allogeneic hematopoietic stem cell transplantation for Chediak-Higashi syndrome. Pediatr Transplant 20: 271-275

3. Kurosawa H, Tanizawa A, Tono C, Watanabe A, Shima H, Ito M, Yuza Y, Hotta N, Muramatsu H, Okada M, Kajiwara R, Moriya Saito A, Mizutani S, Adachi S, Horibe K, Ishii E, Shimada H (2016) Leukostasis in children and adlescents with chronic myeloid leukemia: Japanese Pediatric Leukemia/Lymphoma Study Group. Pediatr Blood Cancer 63: 406-411

4. Hori M, Yasumi T, Shimodera S, Shibata H, Hiejima E, Oda H, Izawa K, Kawai T, Ishimura M, Nakano N, Shirakawa R, Nishikomori R, Takada H, Morita S, Horiuchi H , Ohara O, Ishii E, Heike T (2016) A CD57+ CTL degranulation assay effectively identifies familial hemophagocytic lymphohistiocytosis type 3 patients. J Clin Immunol (in press)

5. Morimoto A, Shioda Y, Imamura T, Kudo K, Kawaguchi H, Sakashita K, Yasui M, Koga Y, Kobayashi R, Ishii E, Fujimoto J, Horibe K, Bessho F, Tsunematsu Y, Imashuku S (2016) Intensified and prolonged therapy comprising cytarabine, vincristine and prednisolone improves outcome in patients with multisystem Langerhans cell histiocytosis: Results of the Japan Langerhans Cell Histiocytosis Study Group-02 Protocol Study. Int J Hematol 104: 99-109

6. Imamura T, Kiyokawa N, Kato M, Imai C, Okamoto Y, Yano M, Ohki K, Yamashita Y, Kodama Y, Saito A, Mori M, Ishimaru S, Deguchi T, Hashii Y, Shimomura Y, Hori T, Kato K, Goto H, Ogawa C, Koh K, Taki T, Manabe A, Sato A, Kikuta A, Adachi S, Horibe K, Ohara A, Watanabe A, Kawano Y, Ishii E, Shimada H (2016) Characterization of pediatric Philadelphia-negative B-cell precursor acute lymphoblastic leukemia with kinase fusions in Japan. Blood Cancer J 6: e419

7. Kodama Y, Manabe A, Kawasaki H, Kato I, Kato K, Sato A, Matsumoto K, Kato, M, Hiramatsu H, Sano H, Kaneko T, Oda M, Saito AM, Adachi S, Horibe K, Mizutani S, Ishii E, Shimada H (2016) Salvage therapy for children with relapsed or refractory Philadelphia chromosome-positive acute lymphoblastic leukemia. Pediatr Blood Cancer (in press)

8. Gao W, Higaki T, Eguchi-Ishimae M, Iwabuki H, Wu Z, Yamamoto E, Takata H, Ohta M, Imoto I, Ishii E, Eguchi M (2016) DGCR6 at proximal part of DiGeorge critical region is involved in conotruncal heart defects. Hum Genome Varia Feb 12; 2: 15004.

9. Poitras JL, Heiser D, Li L, Nguyen B, Nagai K, Duffield AS, Gamper C, Small D. (2016) Dnmt3a deletion cooperates with the Flt3/ITD mutation to drive leukemogenesis in a murine model. Oncotarget (in press)

10. Ichimura T, Yoshida K, Okuno Y, Yujiri T, Nagai K, Nishi M, Shiraishi Y, Ueno H, Toki T, Chiba K, Tanaka H, Muramatsu H, Hara T, Kanno H, Kojima S, Miyano S, Ito E, Ogawa S, Ohga S.(2016) Diagnostic challenge of Diamond-Blackfan anemia in mothers and children by whole-exome sequencing. Int J Hematol (in press)

11. Fujiwara H, Ochi T, Ochi F, Miyazaki Y, Asai H, Narita M, Okamoto S, Mineno J, Kuzushima K, Shiku H, Yasukawa M (2015) Antileukemia multifunctionality of CD4+ T cells genetically engineered by HLA class I-restricted and WT1-specific T-cell receptor gene transfer. Leukemia. 29: 2393-2401

12. Tanaka H, Fujiwara H, Ochi F, Tanimoto K, Casey N, Okamoto S, Mineno J, Kuzushima K, Shiku H, Sugiyama T, Barrett J, Yasukawa M (2016) Development of engineered T cells expressing a chimeric CD16-CD3ζ receptor to improve the clinical efficacy of mogamulizumab therapy against adult T cell leukemia. Clin Cancer Res (in press)

13. Higaki T, Chisaka T, Moritani T, Ohta M, Takata H, Yamauchi T, Ochi F, Yamaguchi Y, Konishi K, Yamamoto E, Eguchi-ishimae M, Eguchi M, Mitani Y, Ishii E (2016) Installation of multiple AED to prevent sudden death in school-aged children. Pediatr Int (in press)

14. Ishida Y, Higaki T, Hayashi M, et al (2016) Factors associated with the specific worries of childhood cancer survivors: Cross-sectional survey in Japan. Pediatr Int 58:331-7

15. Yamamoto E, Higaki T, Nakano T, Watanabe R, Konishi K, Takahashi Y, Ishida Y, Ishii E (2016) Clinical Investigation of Kawasaki Disease in Patients aged Five years or Older at Onset. Jacobs J Pediatr (in press)

16. Tomita H, Higaki T, Kobayashi T, Fujii T, Fujimoto K (2015) Stenting for curved lesions using a novel curved balloon; Preliminary experimental study. J Cardiology 66: 120-124

17. Chisaka T, Mogi M, Nakaoka H, Kan-No H, Tsukuda K, Wang XL, Bai HY, Shan BS, Kukida M, Iwanami J, Higaki T, Ishii E, Horiuchi M (2016) Low-Protein Diet-Induced Fetal Growth Restriction Leads to Exaggerated Proliferative Response to Vascular Injury in Postnatal Life. Am J Hypertens 29: 54-62

18. Kukida M, Mogi M, Ohshima K, Nakaoka H, Iwanami J, Kanno H, Tsukuda K, Chisaka T, Min LJ, Wang XL, Bai HY, Shan BS, Higaki A, Yamauchi T, Okura T, Higaki J, Horiuchi M. (2016) Angiotensin II Type 2 Receptor Inhibits Vascular Intimal Proliferation With Activation of PPARγ. Am J Hypertens. 29: 727-736

19. Mogi M, Kohara K, Nakaoka H, Kan-No H, Tsukuda K, Wang XL, Chisaka T, Bai HY, Shan BS, Kukida M, Iwanami J, Miki T, Horiuchi M. (2016) Diabetic mice exhibited a peculiar alteration in body composition with exaggerated ectopic fat deposition after muscle injury due to anomalous cell differentiation. J Cachexia Sarcopenia Muscle. 7: 213-24

20. Abe Y, Sakai T, Okumura A, Akaboshi S, Fukuda M, Haginoya K, Hamano S, Hirano K, Kikuchi K, Kubota M, Lee S, Maegaki Y, Sanefuji M, Shimozato S, Suzuki M, Suzuki Y, Takahashi M, Watanabe K, Mizuguchi M, Yamanouchi H. (2016) Manifestations and characteristics of congenital adrenal hyperplasia-associated encephalopathy. Brain Dev 38: 638-47

21. Jogamoto T, Yamamoto Y, Fukuda M, Suzuki Y, Imai K, Takahashi Y, Inoue Y, Ohtsuka Y. (2016) Add-on stiripentol elevates serum valproate levels in patients with or without concomitant topiramate therapy. Epilepsy Res (in press)

22. Hamada J, Onum H, Ochi F, Hirai H, Takemoto K, Miyoshi A, Matsushita M, Kadota Y, Ohashi J, Kawamura R, Takata Y, Nishida W, Hashida S, Ishii E, Osawa H. (2016) Endoplasmic reticulum stress induced by tunicamycin increases resistin mRNA through the PERK-ATF4-CHOP pathway in THP-1 human monocytes. J Diabetes Invest 7: 312-323

23. Ayabe T, Fukami M, Ogata T, Kawamura T, Urakami T, Kikuchi N, Yokota I, Ihara K, Takemoto K, Mukai T, Nishii A, Kikuchi T, Mori T, Shimura N, Sasaki G, Kizu R, Takubo N, Soneda S, Fujisawa T, Takaya R, Kizaki Z, Kanzaki S, Hanaki K, Matsuura N, Kasahara Y, Kosaka K, Takahashi T, Minamitani K, Matsuo S, Mochizuki H, Kobayashi K, Koike A, Horikawa R, Teno S, Tsubouchi K, Mochizuki T, Igarashi Y, Amemiya S, Sugihara S; The Japanese Study Group of Insulin Therapy for Childhood and Adolescent Diabetes (JSGIT). Variants associated with autoimmune Type 1 diabetes in Japanese children: Implications for age-specific effects of cis-regulatory haplotypes at 17q12-q21. Diabet Med (in press)

24. Ihara K, Toda N, Fukano C, Ayabe T, Fukami M, Ogata T, Kawamura T, Urakami T, Kikuchi N, Yokota I, Takemoto K, Mukai T, Nishii A, Kikuchi T, Mori T, Shimura N, Sasaki G, Kizu R, Takubo N, Soneda S, Fujisawa T, Takaya R, Kizaki Z, Kanzaki S, Hanaki K, Matsuura N, Kasahara Y, Kosaka K, Takahashi T, Minamitani K, Matsuo S, Mochizuki H, Kobayashi K, Koike A, Horikawa R, Teno S, Tsubouchi K, Mochizuki T, Igarashi Y, Amemiya S and Sugihara S; The Japanese Study Group of Insulin Therapy for Childhood and Adolescent Diabetes (JSGIT). FUT2 Nonsecretor Status Links Type 1 Diabetes Susceptibility in Japanese children. Diabet Med (in press)

25. Ishida Y, Tezuka M, Hayashi M, et al (2016) Japanese childhood cancer survivors’ readiness for care as adults: a cross-sectional survey using the Transition Scales. Psychooncology (in press)

26. Ishida Y, Qiu D, Maeda M, et al (2016) Secondary cancers after a childhood cancer diagnosis: a nationwide hospital-based retrospective cohort study in Japan. Int J Clin Oncol 21:506-16

27. Takenoshita S, Nomura K, Ohde S, Deshpande GA, Sakamoto H, Yoshida H, Urayama K, Bito S, Ishida Y, Shimbo T, Matsui K, Fukui T, Takahashi O (2016) hav ing a Mentor or a Doctoral Degree Is Helpful for Mid-Career Physicians to Publish Papers in Peer-Reviewed Journals.Tohoku J Exp Med (In press)

28. Daida A, Yoshihara H, Inai, I, Hasegawa D, Ishida Y, Urayama KY., Manabe A (2016) Risk factors for hospital-acquired Clostridium difficile infection among pediatric patients with cancer. J Pediatr Hematol Oncol (In press)

29. Mukaino A, Nakane S, Higuchi O, Nakamura H, Miyagi T, Shiroma K, Tokashiki T, Fuseya Y, Ochi K, Umeda M, Nakazato T, Akioka S, Maruoka H, Hayashi M, Igarashi S, Yokoi K, Maeda Y, Sakai W, Matsuo H, Kawakami A (2016) Insights from the ganglionic acetylcholine receptor autoantibodies in patients with Sjogren’s syndrome. Modern Rheumatol 26:708-715

愛媛大学小児科業績 2016

【論文・英文症例報告】

1.Ochi F, Tauchi H, Moritani K, Yonezawa S, Miyamoto H, Suemori K, Ishii E (2016) Rothia mucilaginosa infection in a child with acute lymphoblastic leukemia: a case report. Pediatr Blood Cancer (in press)

2.Hino H, Fukuda M, Suzuki Y, Ishii E (2016) Biphasic cuirass ventilation for treatment of an air leak
after pneumothorax in a patient with nemaline myopathy: a case report. J Anesthesia 30: 1087-1090

3.Tezuka Y, Fukuda M, Watanabe S, Nakano T, Okamoto K, Kuzume K, Yano Y, Eguchi M, Ishimae M, Ishii E, Miyazaki T (2016) Histological characterisation of visceral changes in a patient with type 2 Gaucher disease treated with enzyme replacement therapy. Blood Cells Mol Dis (in press)

4.Tezuka M, Ohta M, Ochi F, Chisaka T, Higaki T, Ishii E (2016) Successful treatment by coil embolization for infantile hemangioma with Kasabach-Meritt syndrome. Pediatric Int (in press)

5.Kojima A, Okamura T, Shikata F, Uchita S, Yamauchi T, Ohta M, Mori H, Tozawa A, Fujii S, Kawanishi Y, Higaki T, Izutani H (2016) Staged Repair of Complete Sternal Cleft and Interrupted Aortic Arch Associated With PHACES Syndrome in a Very Low Birth Weight Infant. Int Surg (in press)

6.Shikata F, Okamura T, Higaki T, Okura M, Kojima A, Uchita S, Izutani H. (2016) Aortic Coarctation 28 Days after an Arterial Switch Operation in a Neonate. Tex Heart Inst J 43: 354-356.

7.Morino T, Ogata T, Horiuchi H, Yamaoka S, Fukuda M, Miura H. (2016) Eight years of follow-up after laminectomy of calcium pyrophosphate crystal deposition in the cervical yellow ligament of patient with Coffin-Lowry syndrome: A case report. Medicine (Baltimore) 95:e4468.

8.Nagai K, Suyama Y, Koga D, Nishi M, Iida C, Tashiro K, Danjo A, Kai K, Matsuo M (2016) Anaplastic Lymphoma Kinase-Positive Anaplastic Large Cell Lymphoma with Cardiac Metastasis and Arterial Tumor Embolisms during First-Course Chemotherapy. Case Rep Oncol. 17; 9: 440-446.

9.Akaike S, Kamoi K, Tezuka M, Tomizawa D, Yoshimura R, Takagi M, Ohno-Matsui K (2016) Ocular manifestation in Myeloid/NK cell precursor acute leukemia: A case diagnosed by the flow cytometry and PCR form aqueous humor. Medline (in press)