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href=\"https:\/\/www.m.ehime-u.ac.jp\/hospital\/kenshu\/wordpress\/wp-content\/uploads\/2020\/11\/\u5199\u771f\uff13.jpg\"><img loading=\"lazy\" decoding=\"async\" class=\"aligncenter size-medium wp-image-1745\" src=\"https:\/\/www.m.ehime-u.ac.jp\/hospital\/kenshu\/wordpress\/wp-content\/uploads\/2020\/11\/\u5199\u771f\uff13-300x225.jpg\" alt=\"\" width=\"300\" height=\"225\" srcset=\"https:\/\/www.m.ehime-u.ac.jp\/hospital\/kenshu\/wordpress\/wp-content\/uploads\/2020\/11\/\u5199\u771f\uff13-300x225.jpg 300w, https:\/\/www.m.ehime-u.ac.jp\/hospital\/kenshu\/wordpress\/wp-content\/uploads\/2020\/11\/\u5199\u771f\uff13-1024x768.jpg 1024w, https:\/\/www.m.ehime-u.ac.jp\/hospital\/kenshu\/wordpress\/wp-content\/uploads\/2020\/11\/\u5199\u771f\uff13-768x576.jpg 768w, https:\/\/www.m.ehime-u.ac.jp\/hospital\/kenshu\/wordpress\/wp-content\/uploads\/2020\/11\/\u5199\u771f\uff13.jpg 1200w\" sizes=\"auto, (max-width: 300px) 100vw, 300px\" \/><\/a><\/p>\n<p>\u226a\u30bb\u30f3\u30bf\u30fc\u9577\u3088\u308a\u30b3\u30e1\u30f3\u30c8\u226b<br \/>\n\u770b\u8b77\u5e2b\u306e\u7686\u3055\u3093\u3001\u304a\u75b2\u308c\u69d8\u3067\u3057\u305f\u3002\u81e8\u5e8a\u63a8\u8ad6\u306f\u5c11\u3057\u96e3\u6613\u5ea6\u306e\u9ad8\u3044\u5185\u5bb9\u3067\u3042\u308a\u3001\u6163\u308c\u306a\u3044\u3068\u3053\u308d\u3082\u3042\u3063\u305f\u3068\u601d\u3044\u307e\u3059\u3002\u3057\u304b\u3057\u3001\u65e5\u3005\u306e\u8a3a\u7642\u306b\u304a\u3044\u3066\u8003\u3048\u306b\u57fa\u3065\u3044\u305f\u8a3a\u65ad\u3092\u5fc3\u304c\u3051\u308b\u3053\u3068\u306b\u3088\u3063\u3066\u5f90\u3005\u306b\u529b\u304c\u3064\u304f\u3068\u601d\u3044\u307e\u3059\u3002\u533b\u5b66\u751f\u306b\u3082\u914d\u5e03\u3057\u3066\u304a\u308a\u307e\u3059\u8cc7\u6599\u3082\u3001\u6c38\u4e45\u4fdd\u5b58\u7248\u3068\u3057\u3066\u6d3b\u7528\u3057\u3066\u4e0b\u3055\u3044\u3002\u5f53\u65e5\u306e6\u75c7\u4f8b\u306e\u3046\u30611\u4f8b\u306f\u767a\u71b1\u304a\u3088\u3073\u60aa\u5bd2\u3092\u4f34\u3063\u305f\u814e\u76c2\u814e\u708e\u306e\u75c7\u4f8b\u3067\u3057\u305f\u3002\u5f8c\u65e5\u300e\u81e8\u5e8a\u75ab\u5b66\u300f\u306e\u7814\u4fee\u3082\u3042\u308b\u305f\u3081\u3001\u30c7\u30fc\u30bf\u306b\u6163\u308c\u3066\u3044\u304f\u5fc5\u8981\u304c\u3042\u308a\u307e\u3059\u3002\u305d\u3053\u3067\u3001\u65e5\u5e38\u8a3a\u7642\u3067\u60a3\u8005\u3055\u3093\u306b\u6700\u3082\u8fd1\u3044\u770b\u8b77\u5e2b\u306b\u3053\u305d\u5f79\u7acb\u3064\u8ad6\u6587\u3092\u3072\u3068\u3064\u7d39\u4ecb\u3057\u307e\u3057\u305f\u3002<\/p>\n<p>\u60aa\u5bd2\u3092\u4f34\u3063\u305f\u767a\u71b1\u60a3\u8005\u306e\u5bd2\u6c17\u306e\u7a0b\u5ea6\u3067\u83cc\u8840\u75c7\u304c\u4e88\u6e2c\u3067\u304d\u308b\u3001\u5fb3\u7530\u5b89\u6625\u5148\u751f\u306e\u6709\u540d\u306a\u8ad6\u6587\u3067\u3059\u3002<br \/>\nAm J Med 2005;118:1417.\uff08<a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/16378800\/\">https:\/\/pubmed.ncbi.nlm.nih.gov\/16378800\/<\/a>)<\/p>\n<p>\u672c\u8ad6\u6587\u3067\u306f\u6551\u6025\u5916\u6765\u3092\u4e00\u5b9a\u671f\u9593\u306b\u53d7\u8a3a\u3057\u305f\u4f53\u6e2938\u2103\u4ee5\u4e0a\u306e\u5168\u767a\u71b1\u60a3\u8005\uff08N=526\uff09\u3092\u5bfe\u8c61\u306b\u3001\u60aa\u5bd2\u306e\u3042\u308b\u60a3\u8005\u3092\u8efd\u75c7\uff08N=105, \u30b8\u30e3\u30b1\u30c3\u30c8\u306a\u3069\u306e\u4e0a\u7740\u3067\u6539\u5584\uff09\u3001\u4e2d\u7b49\u75c7\uff08N=100, \u6bdb\u5e03\u3067\u6539\u5584\uff09\u304a\u3088\u3073\u91cd\u75c7\uff08N=65, 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