{"id":1416,"date":"2025-06-04T18:13:39","date_gmt":"2025-06-04T09:13:39","guid":{"rendered":"https:\/\/www.m.ehime-u.ac.jp\/school\/anatomy1\/?page_id=1416"},"modified":"2025-06-04T18:13:40","modified_gmt":"2025-06-04T09:13:40","slug":"%e7%a0%94%e7%a9%b6%e6%a5%ad%e7%b8%be%ef%bc%88%e6%ad%a6%e5%86%85%e6%95%99%e6%8e%88%e9%96%a2%e9%80%a3%ef%bc%89","status":"publish","type":"page","link":"https:\/\/www.m.ehime-u.ac.jp\/school\/anatomy1\/?page_id=1416","title":{"rendered":"\u7814\u7a76\u696d\u7e3e\uff08\u6b66\u5185\u6559\u6388\u95a2\u9023\uff09"},"content":{"rendered":"\n

1.         Shimazaki, R., Saito, Y., Awaya, T., Minami, N., Kurosawa, R., Hosokawa, M., Ohara, H., Hayashi, S., Takeuchi, A., Hagiwara, M., Hayashi, Y.K., Noguchi, S., and Nishino, I. Profiling of pathogenic variants in Japanese patients with sarcoglycanopathy. Orphanet J Rare Dis<\/em><\/strong> 2025, 20<\/em>, 1, 10.1186\/s13023-024-03521-2.<\/p>\n\n\n\n

2.         Lee, S.A., Ogawa, M., Saito, Y., Shimazaki, R., Awaya, T., Hosokawa, M., Kurosawa, R., Ohara, H., Takeuchi, A., Hayashi, S., Goto, Y.I., Hagiwara, M., Nishino, I., and Noguchi, S. Substitutions of nucleotides at the 3' ends of COL6A1\/2\/3 exons induce exon skipping associated with collagen VI-related muscular dystrophies and therapeutic strategies. Genet. Med.<\/em><\/strong> 2025, 101431, 10.1016\/j.gim.2025.101431.<\/p>\n\n\n\n

3.         Ogi, Y., Egi, H., Ishimaru, K., Koga, S., Yoshida, M., Kikuchi, S., Akita, S., Sugishita, H., Matsumoto, H., Shimokawa, T., Takeuchi, A., and Watanabe, Y. Cadaveric and CT angiography study of vessels around the transverse colon mesentery. World J Surg Oncol<\/em><\/strong> 2023, 21<\/em>, 36, 10.1186\/s12957-023-02919-9.<\/p>\n\n\n\n

4.         Khan, S., Takeuchi, A., Nabeka, H., Khan, F., Shimokawa, T., Takanezawa, S., Saitou, T., Imamura, T., Tachibana, T., Nishizono, A., Hamada, F., and Matsuda, S. Administration of prosaposin-derived neurotrophic factor to neural tube defects facilitates regeneration and restores neurological functions. iScience<\/em><\/strong> 2023, 26<\/em>, 106277, 10.1016\/j.isci.2023.106277.<\/p>\n\n\n\n

5.         Kanemitsu, E., Zhao, X., Iwaisako, K., Inoue, A., Takeuchi, A., Yagi, S., Masumoto, H., Ohara, H., Hosokawa, M., Awaya, T., Aoki, J., Hatano, E., Uemoto, S., and Hagiwara, M. Antagonist of sphingosine 1-phosphate receptor 3 reduces cold injury of rat donor hearts for transplantation. Transl Res<\/em><\/strong> 2023, 255<\/em>, 26-36, 10.1016\/j.trsl.2022.11.003.<\/p>\n\n\n\n

6.         Takeuchi, A., Takahashi, Y., Iida, K., Hosokawa, M., Irie, K., Ito, M., Brown, J.B., Ohno, K., Nakashima, K., and Hagiwara, M. Identification of Qk as a Glial Precursor Cell Marker that Governs the Fate Specification of Neural Stem Cells to a Glial Cell Lineage. Stem Cell Reports<\/em><\/strong> 2020, 15<\/em>, 883-897, 10.1016\/j.stemcr.2020.08.010.<\/p>\n\n\n\n

7.         Iida, K., Hagiwara, M., and Takeuchi, A. Multilateral Bioinformatics Analyses Reveal the Function-Oriented Target Specificities and Recognition of the RNA-Binding Protein SFPQ. iScience<\/em><\/strong> 2020, 23<\/em>, 101325, 10.1016\/j.isci.2020.101325.<\/p>\n\n\n\n

8.         Kurokawa, R., Takeuchi, A., Shiina, N., Katahira, M., Yamashita, T., Matsuno, Y., Hitachi, K., Ishigaki, S., Haamad, N., Yoneda, R., Ueda, N., Iida, K., Hosokawa, M., Hagiwara, M., Iida, M., Mashima, T., Yamaoki, Y., So, M., Nagata, T., Sobue, G., Kondo, K., Watanabe, H., and Uchihashi, T. Versatility of RNA-Binding Proteins in Living Cells. Biomedical Sciences<\/em><\/strong> 2019, 5<\/em>, 7-13, 10.11648\/j.bs.20190501.12.<\/p>\n\n\n\n

9.         Hosokawa, M., Takeuchi, A., Tanihata, J., Iida, K., Takeda, S., and Hagiwara, M. Loss of RNA-Binding Protein Sfpq Causes Long-Gene Transcriptopathy in Skeletal Muscle and Severe Muscle Mass Reduction with Metabolic Myopathy. iScience<\/em><\/strong> 2019, 13<\/em>, 229-242, 10.1016\/j.isci.2019.02.023.<\/p>\n\n\n\n

10.        Takeuchi, A., Iida, K., Tsubota, T., Hosokawa, M., Denawa, M., Brown, J.B., Ninomiya, K., Ito, M., Kimura, H., Abe, T., Kiyonari, H., Ohno, K., and Hagiwara, M. Loss of Sfpq Causes Long-Gene Transcriptopathy in the Brain. Cell Rep<\/em><\/strong> 2018, 23<\/em>, 1326-1341, 10.1016\/j.celrep.2018.03.141.<\/p>\n\n\n\n

11.        Yoshida, M., Kataoka, N., Miyauchi, K., Ohe, K., Iida, K., Yoshida, S., Nojima, T., Okuno, Y., Onogi, H., Usui, T., Takeuchi, A., Hosoya, T., Suzuki, T., and Hagiwara, M. Rectifier of aberrant mRNA splicing recovers tRNA modification in familial dysautonomia. Proc. Natl. Acad. Sci. USA<\/em><\/strong> 2015, 112<\/em>, 2764-2769, 10.1073\/pnas.1415525112.<\/p>\n\n\n\n

12.        Ohnishi, T., Yanazawa, M., Sasahara, T., Kitamura, Y., Hiroaki, H., Fukazawa, Y., Kii, I., Nishiyama, T., Kakita, A., Takeda, H., Takeuchi, A., Arai, Y., Ito, A., Komura, H., Hirao, H., Satomura, K., Inoue, M., Muramatsu, S., Matsui, K., Tada, M., Sato, M., Saijo, E., Shigemitsu, Y., Sakai, S., Umetsu, Y., Goda, N., Takino, N., Takahashi, H., Hagiwara, M., Sawasaki, T., Iwasaki, G., Nakamura, Y., Nabeshima, Y., Teplow, D.B., and Hoshi, M. Na, K-ATPase alpha3 is a death target of Alzheimer patient amyloid-beta assembly. Proc. Natl. Acad. Sci. USA<\/em><\/strong> 2015, 112<\/em>, E4465-4474, 10.1073\/pnas.1421182112.<\/p>\n\n\n\n

13.        Sims-Lucas, S., Cusack, B., Baust, J., Eswarakumar, V.P., Masatoshi, H., Takeuchi, A., and Bates, C.M. Fgfr1 and the IIIc isoform of Fgfr2 play critical roles in the metanephric mesenchyme mediating early inductive events in kidney development. Dev. Dyn.<\/em><\/strong> 2011, 240<\/em>, 240-249, 10.1002\/dvdy.22501.<\/p>\n\n\n\n

14.        Takeuchi, A., Hosokawa, M., Nojima, T., and Hagiwara, M. Splicing reporter mice revealed the evolutionally conserved switching mechanism of tissue-specific alternative exon selection. PLoS One<\/em><\/strong> 2010, 5<\/em>, e10946, 10.1371\/journal.pone.0010946.<\/p>\n\n\n\n

15.        Takeuchi, A., Hamasaki, T., Litwack, E.D., and O'Leary, D.D. Novel IgCAM, MDGA1, expressed in unique cortical area- and layer-specific patterns and transiently by distinct forebrain populations of Cajal-Retzius neurons. Cereb. Cortex<\/em><\/strong> 2007, 17<\/em>, 1531-1541, bhl064 [pii]<\/p>\n\n\n\n

10.1093\/cercor\/bhl064.<\/p>\n\n\n\n

16.        O'Leary, D.D., Chou, S.J., Hamasaki, T., Sahara, S., Takeuchi, A., Thuret, S., and Leingartner, A. Regulation of laminar and area patterning of mammalian neocortex and behavioural implications. Novartis Foundation Symposium<\/em><\/strong> 2007, 288<\/em>, 141-159; discussion 159-164, 276-181.<\/p>\n\n\n\n

17.        Takeuchi, A., and O'Leary, D.D. Radial migration of superficial layer cortical neurons controlled by novel Ig cell adhesion molecule MDGA1. J. Neurosci.<\/em><\/strong> 2006, 26<\/em>, 4460-4464, 26\/17\/4460 [pii]<\/p>\n\n\n\n

10.1523\/JNEUROSCI.4935-05.2006.<\/p>\n\n\n\n

18.        Takeuchi, A., Mishina, Y., Miyaishi, O., Kojima, E., Hasegawa, T., and Isobe, K. Heterozygosity with respect to Zfp148 causes complete loss of fetal germ cells during mouse embryogenesis. Nat. Genet.<\/em><\/strong> 2003, 33<\/em>, 172-176, 10.1038\/ng1072<\/p>\n\n\n\n

ng1072 [pii].<\/p>\n\n\n\n

19.        Kojima, E., Takeuchi, A., Haneda, M., Yagi, A., Hasegawa, T., Yamaki, K., Takeda, K., Akira, S., Shimokata, K., and Isobe, K. The function of GADD34 is a recovery from a shutoff of protein synthesis induced by ER stress: elucidation by GADD34-deficient mice. FASEB J.<\/em><\/strong> 2003, 17<\/em>, 1573-1575, 10.1096\/fj.02-1184fje<\/p>\n\n\n\n

02-1184fje [pii].<\/p>\n\n\n\n

20.        Takeuchi, A., Miyaishi, O., Kiuchi, K., and Isobe, K. Macrophage colony-stimulating factor is expressed in neuron and microglia after focal brain injury. J. Neurosci. Res.<\/em><\/strong> 2001, 65<\/em>, 38-44, doi.org\/10.1002\/jnr.1125.<\/p>\n\n\n\n

21.        Takeuchi, A., Miyaishi, O., Kiuchi, K., and Isobe, K. Cu\/Zn- and Mn-superoxide dismutases are specifically up-regulated in neurons after focal brain injury. J. Neurobiol.<\/em><\/strong> 2000, 45<\/em>, 39-46, 10.1002\/1097-4695(200010)45:1<39::AID-NEU4>3.0.CO;2-A [pii].<\/p>\n\n\n\n

22.        Hasegawa, T., Takeuchi, A., Miyaishi, O., Xiao, H., Mao, J., and Isobe, K. PTRF (polymerase I and transcript-release factor) is tissue-specific and interacts with the BFCOL1 (binding factor of a type-I collagen promoter) zinc-finger transcription factor which binds to the two mouse type-I collagen gene promoters. Biochem. J.<\/em><\/strong> 2000, 347 Pt 1<\/em>, 55-59.<\/p>\n\n\n\n

23.        Maehara, K., Hasegawa, T., Xiao, H., Takeuchi, A., Abe, R., and Isobe, K. Cooperative interaction of NF-kappaB and C\/EBP binding sites is necessary for manganese superoxide dismutase gene transcription mediated by lipopolysaccharide and interferon-gamma. FEBS Lett.<\/em><\/strong>1999, 449<\/em>, 115-119, S0014579399004081 [pii].<\/p>\n\n\n\n

24.        Takeuchi, A., Isobe, K.I., Miyaishi, O., Sawada, M., Fan, Z.H., Nakashima, I., and Kiuchi, K. Microglial NO induces delayed neuronal death following acute injury in the striatum. Eur. J. Neurosci.<\/em><\/strong> 1998, 10<\/em>, 1613-1620, doi.org\/10.1046\/j.1460-9568.1998.00168.x.<\/p>\n\n\n\n

25.        Yamada, E., Ishiguro, N., Miyaishi, O., Takeuchi, A., Nakashima, I., Iwata, H., and Isobe, K. Differential display analysis of murine collagen-induced arthritis: cloning of the cDNA-encoding murine ATPase inhibitor. Immunology<\/em><\/strong> 1997, 92<\/em>, 571-576, doi: 10.1046\/j.1365-2567.1997.00370.x.<\/p>\n\n\n\n

26.        Nozaki, Y., Hasegawa, Y., Takeuchi, A., Fan, Z.H., Isobe, K.I., Nakashima, I., and Shimokata, K. Nitric oxide as an inflammatory mediator of radiation pneumonitis in rats. American Journal of Physiology: Lung Cellular and Molecular Physiology<\/em><\/strong> 1997, 272<\/em>, L651-658, https:\/\/doi.org\/10.1152\/ajplung.1997.272.4.L651<\/a>.<\/p>\n\n\n\n

27.        Hasegawa, T., Takeuchi, A., Miyaishi, O., Isobe, K., and de Crombrugghe, B. Cloning and characterization of a transcription factor that binds to the proximal promoters of the two mouse type I collagen genes. J. Biol. Chem.<\/em><\/strong> 1997, 272<\/em>, 4915-4923, doi.org\/10.1002\/jnr.1125.<\/p>\n\n\n\n

28.        Aono, K., Isobe, K., Kiuchi, K., Fan, Z.H., Ito, M., Takeuchi, A., Miyachi, M., Nakashima, I., and Nimura, Y. In vitro and in vivo expression of inducible nitric oxide synthase during experimental endotoxemia: involvement of other cytokines. J. Cell. Biochem.<\/em><\/strong> 1997, 65<\/em>, 349-358, 10.1002\/(SICI)1097-4644(19970601)65:3<349::AID-JCB5>3.0.CO;2-S [pii].<\/p>\n","protected":false},"excerpt":{"rendered":"

1.         Shimazaki, R., Saito, Y., Awaya, T., Minami, N., Kuros […]<\/p>\n","protected":false},"author":1,"featured_media":0,"parent":0,"menu_order":0,"comment_status":"closed","ping_status":"closed","template":"","meta":{"_locale":"ja","_original_post":"https:\/\/www.m.ehime-u.ac.jp\/school\/anatomy1\/?page_id=1416","vkexunit_cta_each_option":"","footnotes":""},"class_list":["post-1416","page","type-page","status-publish","hentry","ja"],"_links":{"self":[{"href":"https:\/\/www.m.ehime-u.ac.jp\/school\/anatomy1\/index.php?rest_route=\/wp\/v2\/pages\/1416","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/www.m.ehime-u.ac.jp\/school\/anatomy1\/index.php?rest_route=\/wp\/v2\/pages"}],"about":[{"href":"https:\/\/www.m.ehime-u.ac.jp\/school\/anatomy1\/index.php?rest_route=\/wp\/v2\/types\/page"}],"author":[{"embeddable":true,"href":"https:\/\/www.m.ehime-u.ac.jp\/school\/anatomy1\/index.php?rest_route=\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/www.m.ehime-u.ac.jp\/school\/anatomy1\/index.php?rest_route=%2Fwp%2Fv2%2Fcomments&post=1416"}],"version-history":[{"count":1,"href":"https:\/\/www.m.ehime-u.ac.jp\/school\/anatomy1\/index.php?rest_route=\/wp\/v2\/pages\/1416\/revisions"}],"predecessor-version":[{"id":1417,"href":"https:\/\/www.m.ehime-u.ac.jp\/school\/anatomy1\/index.php?rest_route=\/wp\/v2\/pages\/1416\/revisions\/1417"}],"wp:attachment":[{"href":"https:\/\/www.m.ehime-u.ac.jp\/school\/anatomy1\/index.php?rest_route=%2Fwp%2Fv2%2Fmedia&parent=1416"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}