{"id":1416,"date":"2025-06-04T18:13:39","date_gmt":"2025-06-04T09:13:39","guid":{"rendered":"https:\/\/www.m.ehime-u.ac.jp\/school\/anatomy1\/?page_id=1416"},"modified":"2026-08-06T10:51:51","modified_gmt":"2026-08-06T01:51:51","slug":"%e7%a0%94%e7%a9%b6%e6%a5%ad%e7%b8%be%ef%bc%88%e6%ad%a6%e5%86%85%e6%95%99%e6%8e%88%e9%96%a2%e9%80%a3%ef%bc%89","status":"publish","type":"page","link":"https:\/\/www.m.ehime-u.ac.jp\/school\/anatomy1\/?page_id=1416","title":{"rendered":"\u7814\u7a76\u696d\u7e3e\uff08\u6b66\u5185\u6559\u6388\u95a2\u9023\uff09"},"content":{"rendered":"\n<p class=\"wp-block-paragraph\"><strong>\u539f\u8457<\/strong><\/p>\n\n\n\n<ol class=\"wp-block-list\">\n<li>Hosokawa, M., Kawakami, R., Imami, K., Kurosawa, R., Ishihama, Y., Imamura, T., Hagiwara, M., and\u00a0<strong><u>Takeuchi, A.<\/u><\/strong>\u00a0RNA-dependent SFPQ condensates coordinate multidimensional regulation of extra-long neuronal genes\u00a0<strong><em>Cell Chemical Biology<\/em><\/strong>. <strong><a href=\"https:\/\/www.cell.com\/cell-chemical-biology\/fulltext\/S2451-9456(26)00202-3\"><mark style=\"background-color:rgba(0, 0, 0, 0)\" class=\"has-inline-color has-vivid-cyan-blue-color\">10.1016\/j.chembiol.2026.06.004<\/mark><\/a><\/strong><mark style=\"background-color:rgba(0, 0, 0, 0)\" class=\"has-inline-color has-black-color\">.(2026<\/mark><a href=\"https:\/\/www.cell.com\/cell-chemical-biology\/fulltext\/S2451-9456(26)00202-3\"><mark style=\"background-color:rgba(0, 0, 0, 0)\" class=\"has-inline-color has-black-color\">)<\/mark><\/a>- \ud83c\udfc6 <strong><mark style=\"background-color:rgba(0, 0, 0, 0)\" class=\"has-inline-color has-vivid-red-color\">Lab's Featured Paper<\/mark><\/strong><\/li>\n\n\n\n<li>Okano, M., Yoshino, Y., Verma, A.K., Kumon, H., Mori, H., Hosokawa, M., Iga, J.I., Dwivedi, Y.,\u00a0<strong><u>Takeuchi, A.<\/u><\/strong>, and Ueno, S.I. Altered IRF1-miR-20a-5p regulatory axis in the hippocampus of patients with major depressive disorder.\u00a0<strong><em>Psychiatry Clin. Neurosci.<\/em><\/strong>10.1111\/pcn.70111.(2026)<\/li>\n\n\n\n<li>Masaki, S., Nojima, T., Oshiro-Ideue, T., Suenaga, A.,\u00a0<strong><u>Takeuchi, A.<\/u><\/strong>, Kii, I., Suzuki, K., Tanaka, S., Hagiwara, M., and Kataoka, N. PUF60 is a Critical Regulator of PKM Splicing During Myogenesis.\u00a0<strong><em>Mol. Cell. Biol.<\/em><\/strong>, 1-16. 10.1080\/10985549.2026.2699151.(2026)<\/li>\n\n\n\n<li>Shimazaki, R., Saito, Y., Awaya, T., Minami, N., Kurosawa, R., Hosokawa, M., Ohara, H., Hayashi, S.,\u00a0<strong><u>Takeuchi, A.<\/u><\/strong>, Hagiwara, M., Hayashi, Y.K., Noguchi, S., and Nishino, I. Profiling of pathogenic variants in Japanese patients with sarcoglycanopathy.\u00a0<strong><em>Orphanet J Rare Dis<\/em><\/strong>\u00a0<em>20<\/em>, 1. 10.1186\/s13023-024-03521-2.(2025)<\/li>\n\n\n\n<li>Lee, S.A., Ogawa, M., Saito, Y., Shimazaki, R., Awaya, T., Hosokawa, M., Kurosawa, R., Ohara, H.,\u00a0<strong><u>Takeuchi, A.<\/u><\/strong>, Hayashi, S., Goto, Y.I., Hagiwara, M., Nishino, I., and Noguchi, S. Substitutions of nucleotides at the 3' ends of COL6A1\/2\/3 exons induce exon skipping associated with collagen VI-related muscular dystrophies and therapeutic strategies.\u00a0<strong><em>Genet. Med.<\/em><\/strong>, 101431. 10.1016\/j.gim.2025.101431.(2025)<\/li>\n\n\n\n<li>Ogi, Y., Egi, H., Ishimaru, K., Koga, S., Yoshida, M., Kikuchi, S., Akita, S., Sugishita, H., Matsumoto, H., Shimokawa, T.,\u00a0<strong><u>Takeuchi, A.<\/u><\/strong>, and Watanabe, Y. Cadaveric and CT angiography study of vessels around the transverse colon mesentery.\u00a0<strong><em>World J Surg Oncol<\/em><\/strong>\u00a0<em>21<\/em>, 36. 10.1186\/s12957-023-02919-9.(2023)<\/li>\n\n\n\n<li>Khan, S.,\u00a0<strong><u>Takeuchi, A.<\/u><\/strong>, Nabeka, H., Khan, F., Shimokawa, T., Takanezawa, S., Saitou, T., Imamura, T., Tachibana, T., Nishizono, A., Hamada, F., and Matsuda, S. Administration of prosaposin-derived neurotrophic factor to neural tube defects facilitates regeneration and restores neurological functions.\u00a0<strong><em>iScience<\/em><\/strong>\u00a0<em>26<\/em>, 106277. 10.1016\/j.isci.2023.106277.(2023)<\/li>\n\n\n\n<li>Kanemitsu, E., Zhao, X., Iwaisako, K., Inoue, A.,\u00a0<strong><u>Takeuchi, A.<\/u><\/strong>, Yagi, S., Masumoto, H., Ohara, H., Hosokawa, M., Awaya, T., Aoki, J., Hatano, E., Uemoto, S., and Hagiwara, M. Antagonist of sphingosine 1-phosphate receptor 3 reduces cold injury of rat donor hearts for transplantation.\u00a0<strong><em>Transl Res<\/em><\/strong>\u00a0<em>255<\/em>, 26-36. 10.1016\/j.trsl.2022.11.003.(2023)<\/li>\n\n\n\n<li><strong><u>Takeuchi, A.<\/u><\/strong>, Takahashi, Y., Iida, K., Hosokawa, M., Irie, K., Ito, M., Brown, J.B., Ohno, K., Nakashima, K., and Hagiwara, M. Identification of Qk as a Glial Precursor Cell Marker that Governs the Fate Specification of Neural Stem Cells to a Glial Cell Lineage.\u00a0<strong><em>Stem Cell Reports<\/em><\/strong>\u00a0<em>15<\/em>, 883-897. 10.1016\/j.stemcr.2020.08.010.(2020)<\/li>\n\n\n\n<li>Iida, K., Hagiwara, M., and\u00a0<strong><u>Takeuchi, A.<\/u><\/strong>\u00a0Multilateral Bioinformatics Analyses Reveal the Function-Oriented Target Specificities and Recognition of the RNA-Binding Protein SFPQ.\u00a0<strong><em>iScience<\/em><\/strong>\u00a0<em>23<\/em>, 101325. 10.1016\/j.isci.2020.101325.(2020)<\/li>\n\n\n\n<li>Kurokawa, R.,\u00a0<strong><u>Takeuchi, A.<\/u><\/strong>, Shiina, N., Katahira, M., Yamashita, T., Matsuno, Y., Hitachi, K., Ishigaki, S., Haamad, N., Yoneda, R., Ueda, N., Iida, K., Hosokawa, M., Hagiwara, M., Iida, M., Mashima, T., Yamaoki, Y., So, M., Nagata, T., Sobue, G., Kondo, K., Watanabe, H., and Uchihashi, T. Versatility of RNA-Binding Proteins in Living Cells.\u00a0<strong><em>Biomedical Sciences<\/em><\/strong>\u00a0<em>5<\/em>, 7-13. 10.11648\/j.bs.20190501.12.(2019)<\/li>\n\n\n\n<li>Hosokawa, M.,\u00a0<strong><u>Takeuchi, A.<\/u><\/strong>, Tanihata, J., Iida, K., Takeda, S., and Hagiwara, M. Loss of RNA-Binding Protein Sfpq Causes Long-Gene Transcriptopathy in Skeletal Muscle and Severe Muscle Mass Reduction with Metabolic Myopathy.\u00a0<strong><em>iScience<\/em><\/strong>\u00a0<em>13<\/em>, 229-242. 10.1016\/j.isci.2019.02.023.(2019)<\/li>\n\n\n\n<li><strong><u>Takeuchi, A.<\/u><\/strong>, Iida, K., Tsubota, T., Hosokawa, M., Denawa, M., Brown, J.B., Ninomiya, K., Ito, M., Kimura, H., Abe, T., Kiyonari, H., Ohno, K., and Hagiwara, M. Loss of Sfpq Causes Long-Gene Transcriptopathy in the Brain.\u00a0<strong><em>Cell Rep<\/em><\/strong>\u00a0<em>23<\/em>, 1326-1341. 10.1016\/j.celrep.2018.03.141.(2018)<\/li>\n\n\n\n<li>Yoshida, M., Kataoka, N., Miyauchi, K., Ohe, K., Iida, K., Yoshida, S., Nojima, T., Okuno, Y., Onogi, H., Usui, T.,\u00a0<strong><u>Takeuchi, A.<\/u><\/strong>, Hosoya, T., Suzuki, T., and Hagiwara, M. Rectifier of aberrant mRNA splicing recovers tRNA modification in familial dysautonomia.\u00a0<strong><em>Proc. Natl. Acad. Sci. USA<\/em><\/strong>\u00a0<em>112<\/em>, 2764-2769. 10.1073\/pnas.1415525112.(2015)<\/li>\n\n\n\n<li>Ohnishi, T., Yanazawa, M., Sasahara, T., Kitamura, Y., Hiroaki, H., Fukazawa, Y., Kii, I., Nishiyama, T., Kakita, A., Takeda, H.,\u00a0<strong><u>Takeuchi, A.<\/u><\/strong>, Arai, Y., Ito, A., Komura, H., Hirao, H., Satomura, K., Inoue, M., Muramatsu, S., Matsui, K., Tada, M., Sato, M., Saijo, E., Shigemitsu, Y., Sakai, S., Umetsu, Y., Goda, N., Takino, N., Takahashi, H., Hagiwara, M., Sawasaki, T., Iwasaki, G., Nakamura, Y., Nabeshima, Y., Teplow, D.B., and Hoshi, M. Na, K-ATPase alpha3 is a death target of Alzheimer patient amyloid-beta assembly.\u00a0<strong><em>Proc. Natl. Acad. Sci. USA<\/em><\/strong><em>112<\/em>, E4465-4474. 10.1073\/pnas.1421182112.(2015)<\/li>\n\n\n\n<li>Sims-Lucas, S., Cusack, B., Baust, J., Eswarakumar, V.P., Masatoshi, H.,\u00a0<strong><u>Takeuchi, A.<\/u><\/strong>, and Bates, C.M. Fgfr1 and the IIIc isoform of Fgfr2 play critical roles in the metanephric mesenchyme mediating early inductive events in kidney development.\u00a0<strong><em>Dev. Dyn.<\/em><\/strong>\u00a0<em>240<\/em>, 240-249. 10.1002\/dvdy.22501.(2011)<\/li>\n\n\n\n<li><strong><u>Takeuchi, A.<\/u><\/strong>, Hosokawa, M., Nojima, T., and Hagiwara, M. Splicing reporter mice revealed the evolutionally conserved switching mechanism of tissue-specific alternative exon selection.\u00a0<strong><em>PLoS One<\/em><\/strong>\u00a0<em>5<\/em>, e10946. 10.1371\/journal.pone.0010946.(2010)<\/li>\n\n\n\n<li><strong><u>Takeuchi, A.<\/u><\/strong>, Hamasaki, T., Litwack, E.D., and O'Leary, D.D. Novel IgCAM, MDGA1, expressed in unique cortical area- and layer-specific patterns and transiently by distinct forebrain populations of Cajal-Retzius neurons.\u00a0<strong><em>Cereb. Cortex<\/em><\/strong>\u00a0<em>17<\/em>, 1531-1541. 10.1093\/cercor\/bhl064.(2007)<\/li>\n\n\n\n<li>O'Leary, D.D., Chou, S.J., Hamasaki, T., Sahara, S.,\u00a0<strong><u>Takeuchi, A.<\/u><\/strong>, Thuret, S., and Leingartner, A. Regulation of laminar and area patterning of mammalian neocortex and behavioural implications.\u00a0<strong><em>Novartis Foundation Symposium<\/em><\/strong>\u00a0<em>288<\/em>, 141-159; discussion 159-164, 276-181.(2007)<\/li>\n\n\n\n<li><strong><u>Takeuchi, A.<\/u><\/strong>, and O'Leary, D.D. Radial migration of superficial layer cortical neurons controlled by novel Ig cell adhesion molecule MDGA1.\u00a0<strong><em>J. Neurosci.<\/em><\/strong>\u00a0<em>26<\/em>, 4460-4464. 10.1523\/JNEUROSCI.4935-05.2006.(2006)<\/li>\n\n\n\n<li><strong><u>Takeuchi, A.<\/u><\/strong>, Mishina, Y., Miyaishi, O., Kojima, E., Hasegawa, T., and Isobe, K. Heterozygosity with respect to Zfp148 causes complete loss of fetal germ cells during mouse embryogenesis.\u00a0<strong><em>Nat. Genet.<\/em><\/strong>\u00a0<em>33<\/em>, 172-176. 10.1038\/ng1072.(2003)<\/li>\n\n\n\n<li>Kojima, E.,\u00a0<strong><u>Takeuchi, A.<\/u><\/strong>, Haneda, M., Yagi, A., Hasegawa, T., Yamaki, K., Takeda, K., Akira, S., Shimokata, K., and Isobe, K. The function of GADD34 is a recovery from a shutoff of protein synthesis induced by ER stress: elucidation by GADD34-deficient mice.\u00a0<strong><em>FASEB J.<\/em><\/strong>\u00a0<em>17<\/em>, 1573-1575. 10.1096\/fj.02-1184fje.(2003)<\/li>\n\n\n\n<li><strong><u>Takeuchi, A.<\/u><\/strong>, Miyaishi, O., Kiuchi, K., and Isobe, K. Macrophage colony-stimulating factor is expressed in neuron and microglia after focal brain injury.\u00a0<strong><em>J. Neurosci. Res.<\/em><\/strong>\u00a0<em>65<\/em>, 38-44. doi.org\/10.1002\/jnr.1125.(2001)<\/li>\n\n\n\n<li><strong><u>Takeuchi, A.<\/u><\/strong>, Miyaishi, O., Kiuchi, K., and Isobe, K. Cu\/Zn- and Mn-superoxide dismutases are specifically up-regulated in neurons after focal brain injury.\u00a0<strong><em>J. Neurobiol.<\/em><\/strong>\u00a0<em>45<\/em>, 39-46. 10.1002\/1097-4695(200010)45:1&lt;39::AID-NEU4>3.0.CO;2-A [pii].(2000)<\/li>\n\n\n\n<li>Hasegawa, T.,\u00a0<strong><u>Takeuchi, A.<\/u><\/strong>, Miyaishi, O., Xiao, H., Mao, J., and Isobe, K. PTRF (polymerase I and transcript-release factor) is tissue-specific and interacts with the BFCOL1 (binding factor of a type-I collagen promoter) zinc-finger transcription factor which binds to the two mouse type-I collagen gene promoters.\u00a0<strong><em>Biochem. J.<\/em><\/strong>\u00a0<em>347 Pt 1<\/em>, 55-59.(2000)<\/li>\n\n\n\n<li>Maehara, K., Hasegawa, T., Xiao, H.,\u00a0<strong><u>Takeuchi, A.<\/u><\/strong>, Abe, R., and Isobe, K. Cooperative interaction of NF-kappaB and C\/EBP binding sites is necessary for manganese superoxide dismutase gene transcription mediated by lipopolysaccharide and interferon-gamma.\u00a0<strong><em>FEBS Lett.<\/em><\/strong>\u00a0<em>449<\/em>, 115-119. S0014579399004081 [pii].(1999)<\/li>\n\n\n\n<li><strong><u>Takeuchi, A.<\/u><\/strong>, Isobe, K.I., Miyaishi, O., Sawada, M., Fan, Z.H., Nakashima, I., and Kiuchi, K. Microglial NO induces delayed neuronal death following acute injury in the striatum.\u00a0<strong><em>Eur. J. Neurosci.<\/em><\/strong>\u00a0<em>10<\/em>, 1613-1620. doi.org\/10.1046\/j.1460-9568.1998.00168.x.(1998)<\/li>\n\n\n\n<li>Yamada, E., Ishiguro, N., Miyaishi, O.,\u00a0<strong><u>Takeuchi, A.<\/u><\/strong>, Nakashima, I., Iwata, H., and Isobe, K. Differential display analysis of murine collagen-induced arthritis: cloning of the cDNA-encoding murine ATPase inhibitor.\u00a0<strong><em>Immunology<\/em><\/strong>\u00a0<em>92<\/em>, 571-576. doi: 10.1046\/j.1365-2567.1997.00370.x.(1997)<\/li>\n\n\n\n<li>Nozaki, Y., Hasegawa, Y.,\u00a0<strong><u>Takeuchi, A.<\/u><\/strong>, Fan, Z.H., Isobe, K.I., Nakashima, I., and Shimokata, K. Nitric oxide as an inflammatory mediator of radiation pneumonitis in rats.\u00a0<strong><em>American Journal of Physiology: Lung Cellular and Molecular Physiology<\/em><\/strong>\u00a0<em>272<\/em>, L651-658.\u00a0<a href=\"https:\/\/doi.org\/10.1152\/ajplung.1997.272.4.L651.(1997\">https:\/\/doi.org\/10.1152\/ajplung.1997.272.4.L651.(1997<\/a>)<\/li>\n\n\n\n<li>Hasegawa, T.,\u00a0<strong><u>Takeuchi, A.<\/u><\/strong>, Miyaishi, O., Isobe, K., and de Crombrugghe, B. Cloning and characterization of a transcription factor that binds to the proximal promoters of the two mouse type I collagen genes.\u00a0<strong><em>J. Biol. Chem.<\/em><\/strong>\u00a0<em>272<\/em>, 4915-4923. doi.org\/10.1002\/jnr.1125.(1997)<\/li>\n\n\n\n<li>Aono, K., Isobe, K., Kiuchi, K., Fan, Z.H., Ito, M.,\u00a0<strong><u>Takeuchi, A.<\/u><\/strong>, Miyachi, M., Nakashima, I., and Nimura, Y. In vitro and in vivo expression of inducible nitric oxide synthase during experimental endotoxemia: involvement of other cytokines.\u00a0<strong><em>J. Cell. Biochem.<\/em><\/strong>\u00a0<em>65<\/em>, 349-358. 10.1002\/(SICI)1097-4644(19970601)65:3&lt;349::AID-JCB5>3.0.CO;2-S [pii].(1997)<\/li>\n<\/ol>\n\n\n\n<p class=\"wp-block-paragraph\"><\/p>\n\n\n\n<p class=\"wp-block-paragraph\"><strong>\u66f8\u7c4d<\/strong><\/p>\n\n\n\n<ul class=\"wp-block-list\">\n<li>Kuroyanagi H.,\u00a0<strong><u>Takeuchi, A..<\/u><\/strong>, Nojima T. &amp; Hagiwara M. Chapter 28: Single cell detection of splicing events with fluorescent splicing reporters. Alternative pre-mRNA Splicing: Theory and Protocols.(Stamm S., Smith C., L\u00fchrmann R. ed). Wiley-VCH. (2012)<\/li>\n<\/ul>\n\n\n\n<p class=\"wp-block-paragraph\"><\/p>\n\n\n\n<p class=\"wp-block-paragraph\"><strong>\u7dcf\u8aac<\/strong><\/p>\n\n\n\n<ol class=\"wp-block-list\">\n<li><strong><span style=\"text-decoration: underline;\">\u6b66\u5185\u7ae0\u82f1.<\/span><\/strong>\u00a0\u907a\u4f1d\u5b50\u767a\u73fe\u306b\u304a\u3051\u308bRNA\u00a0\u7d50\u5408\u30bf\u30f3\u30d1\u30af\u8cea\u306e\u591a\u5f69\u306a\u6a5f\u80fd.\u00a0<strong><em>\u5b9f\u9a13\u533b\u5b66\u5897\u520a \u30bb\u30f3\u30c8\u30e9\u30eb\u30c9\u30b0\u30de\u306e\u65b0\u5e38\u8b58<\/em><\/strong>\u00a0\u00a0(<em>\u7b2c\uff13\u7ae0 \uff32\uff2e\uff21\u306e\u65b0\u5e38\u8b58<\/em>), 141-148. ISBN-10\u00a0\u200f\u00a0:\u00a0\u200e\u00a04758104042, ISBN-13\u00a0\u200f\u00a0:\u00a0\u200e\u00a0978-4758104043.(2022)<\/li>\n\n\n\n<li><strong><span style=\"text-decoration: underline;\">\u6b66\u5185\u7ae0\u82f1.<\/span><\/strong> Takeuchi, A.\u00a0\u795e\u7d4c\u5e79\u7d30\u80de\u306e\u30b0\u30ea\u30a2\u65b0\u751f\u3078\u306e\u904b\u547d\u6c7a\u5b9a\u3092\u5236\u5fa1\u3059\u308bRNA\u7d50\u5408\u30bf\u30f3\u30d1\u30af\u8ceaQk\u306e\u767a\u898b.\u00a0<strong><em>\u611b\u5a9b\u533b\u5b66EHIME MEDICAL JOURNAL<\/em><\/strong>\u00a0<em>40<\/em>, 121-127.(2021)<\/li>\n\n\n\n<li><strong><span style=\"text-decoration: underline;\">\u6b66\u5185\u7ae0\u82f1<\/span><\/strong>, \u8429\u539f\u6b63\u654f, Takeuchi, A., and M., H.\u00a0\u53ef\u8996\u5316\u30b9\u30d7\u30e9\u30a4\u30b7\u30f3\u30b0\u30fb\u30ec\u30dd\u30fc\u30bf\u30fc\u30b7\u30b9\u30c6\u30e0\u3067\u958b\u304f\u54fa\u4e73\u985e\u306emRNA\u5236\u5fa1\u306e\u4e16\u754cVisualizing Splicing Reporter System Explores the mRNA Regulation World in Mammal.\u00a0<strong><em>\u7d30\u80de\u5de5\u5b66Cell technology<\/em><\/strong>\u00a0<em>31<\/em>, 698-704.(2012)<\/li>\n\n\n\n<li><strong><span style=\"text-decoration: underline;\">\u6b66\u5185\u7ae0\u82f1<\/span><\/strong>, \u4e09\u54c1\u88d5\u53f8,\u00a0\u78ef\u90e8\u5065\u4e00, Takeuchi, A., Y., M., and Isobe, K.-I. CURRENT TOPICS\uff1aZfp148\u306e\u30cf\u30d7\u30ed\u4e0d\u5168\u306f\u3001\u30de\u30a6\u30b9\u80ce\u4ed4\u767a\u751f\u306b\u304a\u3044\u3066\u751f\u6b96\u7d30\u80de\u306e\u5b8c\u5168\u6d88\u5931\u3092\u8d77\u3053\u3059Heterozygosity with respect to Zfp148 causes complete loss of fetal germ cells during mouse embryogenesis.\u00a0<strong><em>\u5b9f\u9a13\u533b\u5b66Experimental Medicine<\/em><\/strong>\u00a0<em>21<\/em>, 912-915.(2003)<\/li>\n\n\n\n<li>\u78ef\u90e8\u5065\u4e00,\u00a0<strong><span style=\"text-decoration: underline;\">\u6b66\u5185\u7ae0\u82f1<\/span><\/strong>, \u9577\u8c37\u5ddd\u5fe0\u7537,\u00a0\u5927\u6960\u6643\u4e09, Isobe, K.-I., Takeuchi, A., Hasegawa, T., and Ohkusu, K.\u00a0\u52a0\u9f62\u3068\u30a2\u30dd\u30c8\u30fc\u30b7\u30b9Aging and Apoptosis.\u00a0<strong><em>\u81e8\u5e8a\u514d\u75abClinical Immunology\u00a0<\/em><\/strong><em>29<\/em>, 1422-1426.(1997)<\/li>\n\n\n\n<li>\u5bae\u77f3\u7406,\u00a0<strong><span style=\"text-decoration: underline;\">\u6b66\u5185\u7ae0\u82f1<\/span><\/strong>,\u00a0\u78ef\u90e8\u5065\u4e00, Miyaishi, O., Takeuchi, A., and Isobe, K.-I.\u00a0\u5206\u5b50\u751f\u7269\u5b66\u7684\u898b\u5730\u304b\u3089\u307f\u305f\u52a0\u9f62Understanding aging from molecular cell biology.\u00a0<strong><em>\u8033\u9f3b\u54bd\u5589\u79d1\u30fb\u982d\u981a\u90e8\u5916\u79d1Otolaryngology-Head and Neck Surgery<\/em><\/strong>\u00a0<em>15<\/em>, 971-975.(1997)<\/li>\n<\/ol>\n\n\n\n<p class=\"wp-block-paragraph\"><\/p>\n\n\n\n<p class=\"wp-block-paragraph\"><strong>\u7279\u8a31<\/strong><\/p>\n\n\n\n<ul class=\"wp-block-list\">\n<li>\u30b9\u30d7\u30e9\u30a4\u30b7\u30f3\u30b0\u7570\u5e38\u306b\u8d77\u56e0\u3059\u308bRNA\u75c5\u306e\u75c5\u614b\u89e3\u660e\u304a\u3088\u3073\u5275\u85ac\u30b7\u30fc\u30ba\u63a2\u7d22\u306e\u305f\u3081\u306b\u958b\u767a\u3057\u305f\u30c4\u30fc\u30eb\u306b\u95a2\u3059\u308b\u7279\u8a31\uff1a\u300c\u54fa\u4e73\u985e\u751f\u7269\u306b\u304a\u3051\u308b\u9078\u629e\u7684\u30b9\u30d7\u30e9\u30a4\u30b7\u30f3\u30b0\u306e\u767a\u73fe\u30d7\u30ed\u30d5\u30a1\u30a4\u30eb\u304a\u3088\u3073\u5236\u5fa1\u6a5f\u69cb\u3092\u660e\u3089\u304b\u306b\u3059\u308b\u30c8\u30e9\u30f3\u30b9\u30b8\u30a7\u30cb\u30c3\u30af\u30ec\u30dd\u30fc\u30bf\u30fc\u30b7\u30b9\u30c6\u30e0\u300d\u3002\u767a\u660e\u8005\uff1a\u8429\u539f\u6b63\u654f\u3001<strong><span style=\"text-decoration: underline;\">\u6b66\u5185\u7ae0\u82f1<\/span><\/strong>\u3002\u51fa\u9858\u4eba\uff1a\u56fd\u7acb\u5927\u5b66\u6cd5\u4eba\u4eac\u90fd\u5927\u5b66\u3002\u65e5\u672c\u56fd\u7279\u8a31\u7b2c5875009\u53f7\uff08\u767b\u9332\u65e5\uff1a2016\u5e741\u670829\u65e5\uff09\u3002<\/li>\n\n\n\n<li>\u30b9\u30d7\u30e9\u30a4\u30b7\u30f3\u30b0\u7570\u5e38\u306b\u8d77\u56e0\u3059\u308bRNA\u75c5\u306e\u75c5\u614b\u89e3\u660e\u304a\u3088\u3073\u5275\u85ac\u30b7\u30fc\u30ba\u63a2\u7d22\u306e\u305f\u3081\u306b\u958b\u767a\u3057\u305f\u30c4\u30fc\u30eb\u306b\u95a2\u3059\u308b\u7279\u8a31\uff1a\u300cTRANSGENIC REPORTER SYSTEM THAT REVEALS EXPRESSION PROFILES AND REGULATION MECHANISMS OF ALTERNATIVE SPLICING IN MAMMALIAN ORGANISMS\u300d\u3002\u767a\u660e\u8005\uff1aMasatoshi Hagiwara\u3001<strong><span style=\"text-decoration: underline;\">Akihide Takeuchi<\/span><\/strong>\u3002\u51fa\u9858\u4eba\uff1aKyoto University\u3002\u7c73\u56fd\u7279\u8a31 US 9,273,364 B2\uff08\u767b\u9332\u65e5\uff1a2016\u5e745\u670811\u65e5\uff09\u3002<\/li>\n\n\n\n<li>\u30b9\u30d7\u30e9\u30a4\u30b7\u30f3\u30b0\u7570\u5e38\u306b\u8d77\u56e0\u3059\u308bRNA\u75c5\u306e\u75c5\u614b\u89e3\u660e\u304a\u3088\u3073\u5275\u85ac\u30b7\u30fc\u30ba\u63a2\u7d22\u306e\u305f\u3081\u306b\u958b\u767a\u3057\u305f\u30c4\u30fc\u30eb\u306b\u95a2\u3059\u308b\u7279\u8a31\uff1a\u300cTRANSGENIC REPORTER SYSTEM THAT REVEALS EXPRESSION PROFILES AND REGULATION MECHANISMS OF ALTERNATIVE SPLICING IN RODENTS\u300d\u3002\u767a\u660e\u8005\uff1aMasatoshi Hagiwara\u3001<strong><span style=\"text-decoration: underline;\">Akihide Takeuchi<\/span><\/strong>\u3002\u51fa\u9858\u4eba\uff1aKyoto University\u3002\u6b27\u5dde\u7279\u8a31 EP 2576778\uff08\u767b\u9332\u65e5\uff1a2017\u5e744\u67087\u65e5\uff09\u3002<\/li>\n<\/ul>\n\n\n\n<p class=\"wp-block-paragraph\"><\/p>\n","protected":false},"excerpt":{"rendered":"<p>\u539f\u8457 \u66f8\u7c4d \u7dcf\u8aac 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