{"id":494,"date":"2025-12-01T20:01:52","date_gmt":"2025-12-01T11:01:52","guid":{"rendered":"https:\/\/www.m.ehime-u.ac.jp\/school\/biochem2\/?page_id=494"},"modified":"2025-12-25T11:50:25","modified_gmt":"2025-12-25T02:50:25","slug":"research","status":"publish","type":"page","link":"https:\/\/www.m.ehime-u.ac.jp\/school\/biochem2\/research\/","title":{"rendered":"\u7814\u7a76\u30c6\u30fc\u30de"},"content":{"rendered":"<p>\u672c\u7814\u7a76\u5ba4\u306e\u4e3b\u8981\u30c6\u30fc\u30de\u306f\u4ee5\u4e0b\u306e\u901a\u308a\u3067\u3059\u3002<\/p>\n<p>\u25a0 1. SLFN11\u306b\u3088\u308bDNA\u640d\u50b7\u5fdc\u7b54\u306e\u5236\u5fa1<br \/>\n\u2013 \u85ac\u5264\u611f\u53d7\u6027\u306e\u5206\u5b50\u57fa\u76e4<br \/>\n\u2013 \u8907\u88fd\u30d5\u30a9\u30fc\u30af\u5236\u5fa1<br \/>\n\u2013 TP53\u975e\u4f9d\u5b58\u30a2\u30dd\u30c8\u30fc\u30b7\u30b9<\/p>\n<p>\u25a0 2. ssDNA\u30ae\u30e3\u30c3\u30d7\uff08single-stranded DNA gaps\uff09<br \/>\n\u2013 \u30ae\u30e3\u30c3\u30d7\u5f62\u6210\u306e\u5206\u5b50\u57fa\u76e4<br \/>\n\u2013 ssDNA\u30ae\u30e3\u30c3\u30d7\u8a98\u5c0e\u3068\u7d30\u80de\u6b7b<br \/>\n\u2013 \u816b\u760d\u7279\u7570\u6027\u306e\u7406\u89e3<\/p>\n<p>\u25a0 3. Schlafen\u30d5\u30a1\u30df\u30ea\u30fc\u306e\u6a5f\u80fd\u9032\u5316<br \/>\n\u2013 \u975e\u30d2\u30c8\u54fa\u4e73\u985eSLFN13\u306e\u6bd4\u8f03\u89e3\u6790<br \/>\n\u2013 \u6297\u30a6\u30a4\u30eb\u30b9\u6a5f\u80fd\u3068\u306e\u95a2\u4fc2<\/p>\n<p>\u25a0 4. \u81e8\u5e8a\u5fdc\u7528\u30fb\u7cbe\u5bc6\u533b\u7642\uff08Precision Chemotherapy\uff09<br \/>\n\u2013 SLFN11\u306b\u3088\u308b\u6cbb\u7642\u52b9\u679c\u4e88\u6e2c<br \/>\n\u2013 \u526f\u4f5c\u7528\u4f4e\u6e1b\u6226\u7565<br \/>\n\u2013 SLFN11\u3092\u30d0\u30a4\u30aa\u30de\u30fc\u30ab\u30fc\u3068\u3059\u308b\u65b0\u898f\u85ac\u5264\u30fbADC\u3068\u306e\u4f75\u7528\u7814\u7a76<\/p>\n","protected":false},"excerpt":{"rendered":"<p>\u672c\u7814\u7a76\u5ba4\u306e\u4e3b\u8981\u30c6\u30fc\u30de\u306f\u4ee5\u4e0b\u306e\u901a\u308a\u3067\u3059\u3002 \u25a0 1. SLFN11\u306b\u3088\u308bDNA\u640d\u50b7\u5fdc\u7b54\u306e\u5236\u5fa1 \u2013 \u85ac\u5264\u611f\u53d7\u6027\u306e\u5206\u5b50\u57fa\u76e4 \u2013 \u8907\u88fd\u30d5\u30a9\u30fc\u30af\u5236\u5fa1 \u2013 TP53\u975e\u4f9d\u5b58\u30a2\u30dd\u30c8\u30fc\u30b7\u30b9 \u25a0 2. ssDNA\u30ae\u30e3\u30c3\u30d7\uff08single-str [&hellip;]<\/p>\n","protected":false},"author":2,"featured_media":0,"parent":0,"menu_order":0,"comment_status":"closed","ping_status":"closed","template":"","meta":{"site-sidebar-layout":"default","site-content-layout":"","ast-site-content-layout":"default","site-content-style":"default","site-sidebar-style":"default","ast-global-header-display":"","ast-banner-title-visibility":"","ast-main-header-display":"","ast-hfb-above-header-display":"","ast-hfb-below-header-display":"","ast-hfb-mobile-header-display":"","site-post-title":"","ast-breadcrumbs-content":"","ast-featured-img":"","footer-sml-layout":"","ast-disable-related-posts":"","theme-transparent-header-meta":"default","adv-header-id-meta":"","stick-header-meta":"","header-above-stick-meta":"","header-main-stick-meta":"","header-below-stick-meta":"","astra-migrate-meta-layouts":"set","ast-page-background-enabled":"default","ast-page-background-meta":{"desktop":{"background-color":"var(--ast-global-color-5)","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""},"tablet":{"background-color":"","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""},"mobile":{"background-color":"","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""}},"ast-content-background-meta":{"desktop":{"background-color":"var(--ast-global-color-4)","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""},"tablet":{"background-color":"var(--ast-global-color-4)","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""},"mobile":{"background-color":"var(--ast-global-color-4)","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""}},"footnotes":""},"class_list":["post-494","page","type-page","status-publish","hentry"],"_links":{"self":[{"href":"https:\/\/www.m.ehime-u.ac.jp\/school\/biochem2\/wp-json\/wp\/v2\/pages\/494","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/www.m.ehime-u.ac.jp\/school\/biochem2\/wp-json\/wp\/v2\/pages"}],"about":[{"href":"https:\/\/www.m.ehime-u.ac.jp\/school\/biochem2\/wp-json\/wp\/v2\/types\/page"}],"author":[{"embeddable":true,"href":"https:\/\/www.m.ehime-u.ac.jp\/school\/biochem2\/wp-json\/wp\/v2\/users\/2"}],"replies":[{"embeddable":true,"href":"https:\/\/www.m.ehime-u.ac.jp\/school\/biochem2\/wp-json\/wp\/v2\/comments?post=494"}],"version-history":[{"count":4,"href":"https:\/\/www.m.ehime-u.ac.jp\/school\/biochem2\/wp-json\/wp\/v2\/pages\/494\/revisions"}],"predecessor-version":[{"id":602,"href":"https:\/\/www.m.ehime-u.ac.jp\/school\/biochem2\/wp-json\/wp\/v2\/pages\/494\/revisions\/602"}],"wp:attachment":[{"href":"https:\/\/www.m.ehime-u.ac.jp\/school\/biochem2\/wp-json\/wp\/v2\/media?parent=494"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}