{"id":368,"date":"2020-05-12T13:12:55","date_gmt":"2020-05-12T04:12:55","guid":{"rendered":"https:\/\/www.m.ehime-u.ac.jp\/school\/clab\/wordpress\/?page_id=368"},"modified":"2025-11-20T14:34:42","modified_gmt":"2025-11-20T05:34:42","slug":"introduction","status":"publish","type":"page","link":"https:\/\/www.m.ehime-u.ac.jp\/school\/clab\/introduction","title":{"rendered":"\u60a3\u8005\u3055\u3093\u3092\u7d39\u4ecb\u3057\u3066\u3044\u305f\u3060\u304f\u5148\u751f\u65b9\u3078"},"content":{"rendered":"<h3>\u60a3\u8005\u3055\u3093\u3092\u7d39\u4ecb\u3057\u3066\u3044\u305f\u3060\u304f\u5148\u751f\u65b9\u3078<\/h3>\n<h4>\u7cd6\u5c3f\u75c5\u5185\u79d1<\/h4>\n<h5>1, Common disease 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CGM\u5916\u6765\u3001\u30a4\u30f3\u30b9\u30ea\u30f3\u5c0e\u5165\u30d7\u30ed\u30b0\u30e9\u30e0<\/h5>\n<p>\u66f4\u306b\u3001\u6570\u5206\u6bce\u306b5\uff5e14\u65e5\u9593\u9023\u7d9a\u8840\u7cd6\u6e2c\u5b9a\u304c\u3067\u304d\u308b\u6301\u7d9a\u8840\u7cd6\u30e2\u30cb\u30bf\u30ea\u30f3\u30b0 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1\u578b\u7cd6\u5c3f\u75c5(\u6025\u6027\u3001\u7de9\u5f90\u9032\u884c\u3001\u5287\u75c7)\u3001\u907a\u4f1d\u5b50\u7570\u5e38\u306b\u3088\u308b\u7cd6\u5c3f\u75c5<\/h5>\n<p>\u30081\u578b\u7cd6\u5c3f\u75c5\u3084\u907a\u4f1d\u5b50\u7570\u5e38\u306b\u3088\u308b\u7cd6\u5c3f\u75c5\u306f\u5c11\u306a\u304f\u306a\u3044\u3009<br \/>\n\u4e00\u822c\u533b\u5bb6\u306b\u3068\u3063\u3066\u30b3\u30f3\u30c8\u30ed\u30fc\u30eb\u304c\u56f0\u96e3\u306a\u30011\u578b\u7cd6\u5c3f\u75c5\u3001\u907a\u4f1d\u5b50\u7570\u5e38\u306b\u3088\u308b\u7cd6\u5c3f\u75c5\u306e\u8a3a\u65ad\u6cbb\u7642\u3092\u884c\u3063\u3066\u3044\u307e\u3059\u3002\u7d041000\u4e07\u4eba\u306e\u7cd6\u5c3f\u75c5\u60a3\u8005\u306e\u3046\u3061\u3001\u7d045%\u306f1\u578b\u7cd6\u5c3f\u75c5\u30011-2%\u306f\u30df\u30c8\u30b3\u30f3\u30c9\u30ea\u30a2\u7570\u5e38\u306e\u3088\u3046\u306a\u907a\u4f1d\u5b50\u7570\u5e38\u306b\u3088\u308b\u7cd6\u5c3f\u75c5\u3067\u3059\u3002\u5f93\u3063\u3066\u3001\u4e00\u822c\u30af\u30ea\u30cb\u30c3\u30af\u306e\u5916\u6765\u306b\u3082\u3001\u304b\u306a\u308a\u306e\u983b\u5ea6\u30672\u578b\u4ee5\u5916\u306e\u7cd6\u5c3f\u75c5\u60a3\u8005\u304c\u5b58\u5728\u3057\u3066\u3044\u308b\u53ef\u80fd\u6027\u304c\u3042\u308a\u307e\u3059\u3002\u8840\u7cd6\u30b3\u30f3\u30c8\u30ed\u30fc\u30eb\u304c\u4e0a\u624b\u304f\u3044\u304b\u306a\u3044\u60a3\u8005\u3067\u306f\u3001\u4e00\u5ea6\u3001\u8840\u4e2dC\u30da\u30d7\u30c1\u30c9\u3001GAD\u6297\u4f53\u306e\u6e2c\u5b9a\u3092\u65bd\u884c\u3057\u3066\u9802\u304f\u3053\u3068\u304c\u91cd\u8981\u3067\u3059\u3002\u4f8b\u3048\u3070\u3001\u73fe\u5728\u306f\u5185\u670d\u85ac\u3067\u8840\u7cd6\u30b3\u30f3\u30c8\u30ed\u30fc\u30eb\u3067\u304d\u3066\u3044\u3066\u3082\u3001GAD\u6297\u4f53\u967d\u6027\u306e\u5834\u5408\u306f\u7de9\u5f90\u9032\u884c1\u578b\u7cd6\u5c3f\u75c5\u306e\u53ef\u80fd\u6027\u304c\u9ad8\u304f\u3001\u5c06\u6765\u30a4\u30f3\u30b9\u30ea\u30f3\u4f9d\u5b58\u3068\u306a\u308a\u3048\u307e\u3059\u3002\u30df\u30c8\u30b3\u30f3\u30c9\u30ea\u30a2\u907a\u4f1d\u5b50\u7570\u5e38\u306b\u3088\u308b\u7cd6\u5c3f\u75c5\u306f\u3001\u82e5\u5e74\u767a\u75c7\u304c\u591a\u304f\u3001\u5bb6\u65cf\u6b74\u306b\u6bcd\u7cfb\u907a\u4f1d\u3092\u8a8d\u3081\u3001\u611f\u97f3\u6027\u96e3\u8074\u3001\u4f4e\u8eab\u9577\u3001\u795e\u7d4c\u969c\u5bb3\u3001\u5fc3\u7b4b\u969c\u5bb3\u306a\u3069\u3092\u5408\u4f75\u3059\u308b\u3053\u3068\u304c\u7279\u5fb4\u3067\u3059\u3002\u65e9\u671f\u306b\u814e\u4e0d\u5168\u3078\u79fb\u884c\u3059\u308b\u4f8b\u3082\u591a\u304f\u8a8d\u3081\u307e\u3059\u3002\u307e\u305f\u3001\u82e5\u5e74\u767a\u75c7\u30013\u4e16\u4ee3\u4ee5\u4e0a\u306b\u308f\u305f\u308b\u7cd6\u5c3f\u75c5\u5bb6\u7cfb\u306fMODY (maturity-onset diabetes of the young)\u306e\u53ef\u80fd\u6027\u304c\u3042\u308a\u307e\u3059\u3002\u3053\u306e\u3088\u3046\u306a\u907a\u4f1d\u5b50\u7570\u5e38\u306b\u3088\u308b\u7cd6\u5c3f\u75c5\u306f\u3001\u53ef\u80fd\u306a\u9650\u308a\u65e9\u671f\u306b\u8a3a\u65ad\u3092\u884c\u3044\u3001\u65e9\u671f\u304b\u3089\u53b3\u683c\u306a\u6cbb\u7642\u3092\u958b\u59cb\u3059\u308b\u3053\u3068\u304c\u91cd\u8981\u3067\u3059\u3002<br \/>\n\u91cd\u7be4\u306a\u30b1\u30c8\u30a2\u30b7\u30c9\u30fc\u30b7\u30b9\u3092\u5f15\u304d\u8d77\u3053\u3057\u3001\u8a3a\u65ad\u304c\u9045\u308c\u308c\u3070\u3001\u6570\u65e5\u3067\u6b7b\u4ea1\u3059\u308b\u53ef\u80fd\u6027\u3082\u3042\u308b\u201c\u5287\u75c71\u578b\u7cd6\u5c3f\u75c5&#8221;\u306e\u521d\u671f\u75c7\u72b6\u306f\u201c\u304b\u305c\u75c7\u72b6\u3084\u8179\u75db&#8221;\u3067\u3042\u308a\u3001\u307e\u305a\u3001\u4e00\u822c\u5916\u6765\u3084\u3001\u6551\u6025\u5916\u6765\u3092\u53d7\u8a3a\u3059\u308b\u53ef\u80fd\u6027\u304c\u3042\u308a\u307e\u3059\u3002\u307e\u305f\u3001\u598a\u5a20\u4e2d\u767a\u75c7\u3059\u308b\u4f8b\u3082\u8a8d\u3081\u3089\u308c\u307e\u3059\u3002\u6fc0\u3057\u3044\u53e3\u6e07\u3084\u3001\u691c\u5c3f\u306b\u3088\u308b\u9ad8\u5ea6\u306a\u5c3f\u7cd6\u3068\u5c3f\u30b1\u30c8\u30f3\u3001\u610f\u8b58\u969c\u5bb3\u306a\u3069\u304c\u8a3a\u65ad\u306e\u5951\u6a5f\u3068\u306a\u308a\u307e\u3059\u3002\u3053\u306e\u3088\u3046\u306a\u60a3\u8005\u3055\u3093\u304c\u3044\u3089\u3063\u3057\u3083\u3044\u307e\u3057\u305f\u3089\u305c\u3072\u3054\u7d39\u4ecb\u304f\u3060\u3055\u3044\u3002<\/p>\n<h5>5, CSII\u3001SAP \u306b\u3088\u308b\u6cbb\u7642<\/h5>\n<p>\u30a4\u30f3\u30b9\u30ea\u30f3\u983b\u56de\u6295\u4e0e\u6cd5\u3067\u306f\u5341\u5206\u306a\u8840\u7cd6\u30b3\u30f3\u30c8\u30ed\u30fc\u30eb\u304c\u5f97\u3089\u308c\u306a\u3044\u30d6\u30ea\u30c3\u30c8\u30eb\u578b\u7cd6\u5c3f\u75c5\u3084\u3001\u53b3\u91cd\u306a\u8840\u7cd6\u30b3\u30f3\u30c8\u30ed\u30fc\u30eb\u304c\u5fc5\u8981\u3068\u3055\u308c\u308b\u7cd6\u5c3f\u75c5\u598a\u5a66\u306a\u3069\u306e\u60a3\u8005\u3055\u3093\u3092\u4e2d\u5fc3\u306b\u3001\u30d7\u30ed\u30b0\u30e9\u30e0\u53ef\u80fd\u306a\u30a4\u30f3\u30b9\u30ea\u30f3\u30dd\u30f3\u30d7\u306b\u3088\u308b\u30a4\u30f3\u30b9\u30ea\u30f3\u6301\u7d9a\u76ae\u4e0b\u6ce8\u5165\u6cd5 (CSII)\u3084\u3001\u30ea\u30a2\u30eb\u30bf\u30a4\u30e0CGM\u3068CSII\u3092\u9023\u52d5\u3055\u305b\u305f\u6a5f\u5668 (SAP)\u306e\u5c0e\u5165\u3082\u7a4d\u6975\u7684\u306b\u884c\u3063\u3066\u304a\u308a\u307e\u3059\u3002CSII\u3084SAP\u306e\u5c0e\u5165\u306b\u3088\u308a\u3001\u60a3\u8005\u3055\u3093\u306f\u3001\u5c02\u9580\u533b\u306e\u4e8b\u524d\u6307\u793a\u306e\u3082\u3068\u3001\u671d\u6669\u306e\u65e5\u5185\u5909\u52d5\u306b\u3042\u308f\u305b\u305f\u30a4\u30f3\u30b9\u30ea\u30f3\u6ce8\u5165\u306e\u30d7\u30ed\u30b0\u30e9\u30df\u30f3\u30b0\u306f\u3082\u3061\u308d\u3093\u3001\u65e5\u3005\u5909\u308f\u308b\u751f\u6d3b\u5f37\u5ea6\u3084\u3001\u73fe\u5728\u306e\u8840\u7cd6\u5024\u3001\u4eca\u304b\u3089\u6442\u53d6\u3059\u308b\u70ad\u6c34\u5316\u7269\u91cf\u306a\u3069\u306b\u5fdc\u3058\u3066\u3001\u30a4\u30f3\u30b9\u30ea\u30f3\u6295\u4e0e\u91cf\u3092\u305d\u306e\u5834\u3067\u5909\u66f4\u3059\u308b\u3053\u3068\u304c\u3067\u304d\u307e\u3059\u3002\u3053\u306e\u3088\u3046\u306a\u3001\u30b7\u30b9\u30c6\u30e0\u306b\u3088\u308a\u30011\u578b\u7cd6\u5c3f\u75c5\u3067\u3042\u3063\u3066\u3082\u3001\u307b\u3068\u3093\u3069\u6b63\u5e38\u306a\u65b9\u3068\u540c\u3058\u30ec\u30d9\u30eb\u306e\u8840\u7cd6\u30d7\u30ed\u30d5\u30a1\u30a4\u30eb\u3092\u9054\u6210\u3059\u308b\u3053\u3068\u304c\u53ef\u80fd\u3067\u3059\u3002\u7cd6\u5c3f\u75c5\u5185\u79d1\u3067\u306f\u3001\u3053\u306eCSII\u3001SAP\u3092\u7528\u3044\u305f\u6cbb\u7642\u3092\u5165\u9662\u4e2d\u3060\u3051\u3067\u306a\u304f\u5916\u6765\u3067\u3082\u7d9a\u3051\u308b\u3053\u3068\u304c\u53ef\u80fd\u3067\u3059\u3002\u3053\u306e\u3088\u3046\u306a\u60a3\u8005\u3055\u3093\u304c\u3044\u3089\u3063\u3057\u3083\u3044\u307e\u3057\u305f\u3089\u305c\u3072\u3054\u7d39\u4ecb\u304f\u3060\u3055\u3044\u3002<\/p>\n<h5>6, \u6700\u8fd1\u306e\u8a71\u984c<\/h5>\n<p>CGM\u3084\u30ea\u30a2\u30eb\u30bf\u30a4\u30e0CGM\u306e\u767b\u5834\u306b\u3088\u308a\u3001\u8840\u7cd6\u306e\u8a55\u4fa1\u306f\u81ea\u5df1\u8840\u7cd6\u6e2c\u5b9a (SMBG)\u306b\u3088\u308b1\u65e54\u56de\u306e\u70b9\u304b\u308924\u6642\u9593\u306e\u9023\u7d9a\u3057\u305f\u7dda\u3068\u306a\u308a\u307e\u3057\u305f\u3002\u3053\u308c\u306f\u3001\u7cd6\u5c3f\u75c5\u6cbb\u7642\u306b\u3068\u3063\u3066\u3001\u5927\u304d\u306a\u30d1\u30e9\u30c0\u30a4\u30e0\u30b7\u30d5\u30c8\u3068\u8a00\u3048\u307e\u3059\u3002<br \/>\n\u4f8b\u3048\u3070\u3001\u8868\u306f\u3042\u308b\u7cd6\u5c3f\u75c5\u60a3\u8005\u306eSMBG\u306e\u7d50\u679c\u3067\u3059\u3002\u672c\u75c7\u4f8b\u306f\uff11\u578b\u7cd6\u5c3f\u75c5\u3067\u8840\u7cd6\u304c\u4e0d\u5b89\u5b9a\u3067\u3042\u308a\u3001\u57fa\u790e\u30a4\u30f3\u30b9\u30ea\u30f3\u3068\u3057\u3066\u30b0\u30e9\u30eb\u30ae\u30f3\u3092\u671d\u59156 \u5358\u4f4d\u306e2 \u56de\u6ce8\u5c04\u3092\u3057\u3066\u3044\u307e\u3057\u305f\u3002SMBG \u306e\u7d50\u679c\u304b\u3089\u306f\u671d\u3068\u7720\u524d\u306e\u9ad8\u8840\u7cd6\u3092\u8a8d\u3081\u305f\u305f\u3081\u57fa\u790e\u30a4\u30f3\u30b9\u30ea\u30f3\u304c\u4e0d\u8db3\u3057\u3066\u3044\u308b\u3088\u3046\u306b\u601d\u308f\u308c\u3001\u5f93\u6765\u3067\u3042\u308c\u3070\u7720\u524d\u306e\u57fa\u790e\u30a4\u30f3\u30b9\u30ea\u30f3\u3092\u5897\u91cf\u3057\u3066\u3044\u305f\u304b\u3082\u3057\u308c\u307e\u305b\u3093\u3002<br \/>\n\u3057\u304b\u3057\u3001\u672c\u75c7\u4f8b\u3067\u306f\u3001\u306f\u540c\u6642\u306bCGM \u306b\u3088\u308b3 \u65e5\u9593\u30015 \u5206\u6bce\u306e\u9023\u7d9a\u8840\u7cd6\u6e2c\u5b9a\u3082\u884c\u308f\u308c\u3066\u304a\u308a (\u56f31\u3001CGM \u306e\u6a5f\u7a2e\u304ciPro2 \u3067\u3042\u3063\u305f\u305f\u3081\u3001\u6e2c\u5b9a\u7d50\u679c\u306f8\u670812 \u65e5\u306e\u5348\u5f8c\u306b\u660e\u3089\u304b\u306b\u306a\u3063\u3066\u3044\u308b)\u3001\u305d\u306e\u7d50\u679c\u30018 \u670811\u65e5\u304a\u3088\u307312\u65e5\u306e\u6df1\u591c\u304b\u3089\u65e9\u671d\u306b\u304b\u3051\u3066\u4f4e\u8840\u7cd6\u3092\u8a8d\u3081\u3066\u3044\u307e\u3057\u305f\u3002\u5f93\u3063\u3066\u3001\u671d\u306b\u8a8d\u3081\u305f\u9ad8\u8840\u7cd6\u306f\u4f4e\u8840\u7cd6\u306b\u3088\u308bSomogyi \u52b9\u679c (\u6df1\u591c\u306e\u4f4e\u8840\u7cd6\u306b\u53cd\u5fdc\u3057\u3066\u5206\u6ccc\u3055\u308c\u305f\u30a4\u30f3\u30b9\u30ea\u30f3\u62ee\u6297\u30db\u30eb\u30e2\u30f3\u306b\u3088\u308b)\u304c\u4e00\u56e0\u3068\u8003\u3048\u3089\u308c\u307e\u3057\u305f\u3002\u305d\u3053\u3067\u3001\u57fa\u790e\u30a4\u30f3\u30b9\u30ea\u30f3\u3092\u3080\u3057\u308d\u6e1b\u91cf\u3057\u3001\u4f5c\u7528\u6642\u9593\u306e\u3088\u308a\u9577\u3044\u30c7\u30b0\u30eb\u30c7\u30af\u306b\u5909\u66f4\u3057\u305f\u7d50\u679c\u3001\u6df1\u591c\u306e\u4f4e\u8840\u7cd6\u3001\u304a\u3088\u3073\u671d\u306e\u8840\u7cd6\u306e\u6539\u5584\u3092\u8a8d\u3081\u305f\u307e\u3057\u305f\u3002\u305d\u306e\u5f8c\u3001\u4ed6\u306e\u75c7\u4f8b\u3067\u3082\u3001CGM \u306b\u3088\u308b\u9023\u7d9a\u8840\u7cd6\u6e2c\u5b9a\u306e\u7d50\u679c\u3001\u6df1\u591c\u304b\u3089\u65e9\u671d\u306b\u304b\u3051\u3066\u306e\u4f4e\u8840\u7cd6\u3068\u671d\u306e\u9ad8\u8840\u7cd6\u3068\u3044\u3046\u73fe\u8c61\u3092\u3001\u7279\u306b\u9ad8\u9f62\u8005\u3092\u4e2d\u5fc3\u306b\u8907\u6570\u4f8b\u7d4c\u9a13\u3057\u305f\u305f\u3081\u3001\u3053\u308c\u3089\u306e\u75c7\u4f8b\u3067\u306f\u6301\u52b9\u578b\u30a4\u30f3\u30b9\u30ea\u30f3\u306e\u6295\u4e0e\u3092\u7720\u524d\u3067\u306f\u306a\u304f\u671d\u306b\u5909\u66f4\u3057\u3066\u3044\u307e\u3059\u3002CGM \u306b\u3088\u308b\u9023\u7d9a\u8840\u7cd6\u6e2c\u5b9a\u306f\u3001SMBG \u3067\u306f\u898b\u9003\u3057\u304c\u3061\u306a\u6642\u9593\u5e2f\u306e\u4f4e\u8840\u7cd6\u3001\u9ad8\u8840\u7cd6\u3092\u660e\u3089\u304b\u306b\u3067\u304d\u3001\u6cbb\u7642\u65b9\u91dd\u306e\u6c7a\u5b9a\u306b\u6709\u7528\u3067\u3059\u3002<br \/>\n\u5f53\u79d1\u3067\u306f\u3001CGM\u5916\u6765\u3092\u958b\u8a2d\u3057\u3001\u5fa1\u7d39\u4ecb\u9802\u3044\u305f\u5148\u751f\u306b\u3001CGM\u306e\u7d50\u679c\u3068\u3068\u3082\u306b\u3001\u8840\u7cd6\u5909\u52d5\u306b\u57fa\u3065\u304f\u30a4\u30f3\u30b9\u30ea\u30f3\u6cbb\u7642\u65b9\u91dd\u306e\u63d0\u6848\u306a\u3069\u3092\u884c\u3063\u3066\u3044\u307e\u3059\u3002\u3053\u306e\u3088\u3046\u306a\u60a3\u8005\u3055\u3093\u304c\u3044\u3089\u3063\u3057\u3083\u3044\u307e\u3057\u305f\u3089\u305c\u3072\u3054\u7d39\u4ecb\u304f\u3060\u3055\u3044\u3002<\/p>\n<p><img loading=\"lazy\" decoding=\"async\" class=\"aligncenter size-full wp-image-795\" src=\"https:\/\/www.m.ehime-u.ac.jp\/school\/clab\/wp-content\/uploads\/2020\/06\/\u56f32.png\" alt=\"\" width=\"1977\" height=\"823\" srcset=\"https:\/\/www.m.ehime-u.ac.jp\/school\/clab\/wp-content\/uploads\/2020\/06\/\u56f32.png 1977w, https:\/\/www.m.ehime-u.ac.jp\/school\/clab\/wp-content\/uploads\/2020\/06\/\u56f32-300x125.png 300w, https:\/\/www.m.ehime-u.ac.jp\/school\/clab\/wp-content\/uploads\/2020\/06\/\u56f32-1024x426.png 1024w, https:\/\/www.m.ehime-u.ac.jp\/school\/clab\/wp-content\/uploads\/2020\/06\/\u56f32-768x320.png 768w, https:\/\/www.m.ehime-u.ac.jp\/school\/clab\/wp-content\/uploads\/2020\/06\/\u56f32-1536x639.png 1536w\" sizes=\"auto, (max-width: 1977px) 100vw, 1977px\" \/><\/p>\n<h5>7, \u7814\u7a76\u6210\u679c<\/h5>\n<p>\u73fe\u5728\u5f53\u79d1\u3067\u306f\u30a4\u30f3\u30b9\u30ea\u30f3\u62b5\u6297\u6027\u95a2\u9023\u907a\u4f1d\u5b50\u306e\u30d7\u30ed\u30e2\u30fc\u30bf\u30fcSNP\u3092\u6a19\u7684\u3068\u3057\u305f\u30e1\u30bf\u30dc\u30ea\u30c3\u30af\u30b7\u30f3\u30c9\u30ed\u30fc\u30e0\u306e\u4e88\u9632\u30fb\u8a3a\u65ad\u6cd5\u306b\u3064\u3044\u3066\u306e\u7814\u7a76\u3092\u3059\u3059\u3081\u3066\u304a\u308a\u307e\u3059\u3002\u6559\u6388\u306e\u5927\u6fa4\u3089\u306f\u30ec\u30b8\u30b9\u30c1\u30f3\u306eSNP-420\u306eG\/G\u578b\u304c2\u578b\u7cd6\u5c3f\u75c5\u611f\u53d7\u6027\u907a\u4f1d\u5b50\u3067\u3042\u308b\u3053\u3068\u3092\u767a\u898b\u3057\u307e\u3057\u305f\u3002 (Am J Hum Genet 75: 678, 2004)\u3002 \u5c06\u6765\u7684\u306b\u306f\u3001\u907a\u4f1d\u5b50\u691c\u67fb\u306b\u57fa\u3065\u304f\u30d7\u30ec\u30b7\u30b8\u30e7\u30f3\u30e1\u30c7\u30a3\u30b9\u30f3\u306e\u78ba\u7acb\u3092\u3081\u3056\u3057\u3066\u3044\u307e\u3059\u30021\u578b\u7cd6\u5c3f\u75c5\u306b\u3064\u3044\u3066\u3082\u770c\u5185\u306e\u591a\u65bd\u8a2d\u5171\u540c\u7814\u7a76\u306eEhime Study\u3068\u3057\u3066\u3001HLA\u3084\u81ea\u5df1\u6297\u4f53\u3068\u306e\u95a2\u9023\u3092\u5831\u544a\u3057\u3066\u304a\u308a\u3001\u6211\u3005\u306e\u7814\u7a76\u6210\u679c\u306f\u5287\u75c7\uff11\u578b\u7cd6\u5c3f\u75c5\u306e\u8a3a\u65ad\u57fa\u6e96\u306a\u3069\u306b\u3082\u63a1\u7528\u3055\u308c\u3066\u3044\u307e\u3059 (Diabetes Care 25: 995, 2002\u3001Diabetes 53: 2684, 2004)\u3002<\/p>\n<h4>\u5916\u6765\u62c5\u5f53\u533b\u5c02\u9580\u5206\u91ce<\/h4>\n<table style=\"border-collapse: collapse; width: 100%;\">\n<tbody>\n<tr>\n<td style=\"width: 50%;\">\u6c0f\u540d<\/td>\n<td style=\"width: 50%;\">\u9ad8\u7530\u3000\u5eb7\u5fb3 (\u305f\u304b\u305f\u3000\u3084\u3059\u306e\u308a)<\/td>\n<\/tr>\n<tr>\n<td style=\"width: 50%;\">\u5f79\u8077<\/td>\n<td style=\"width: 50%;\">\u6559\u6388<\/td>\n<\/tr>\n<tr>\n<td style=\"width: 50%;\">\u6240\u5c5e\u8b1b\u5ea7<\/td>\n<td style=\"width: 50%;\">\u611b\u5a9b\u5927\u5b66\u5927\u5b66\u9662\u7cd6\u5c3f\u75c5\u5185\u79d1\u5b66\u8b1b\u5ea7<\/td>\n<\/tr>\n<tr>\n<td style=\"width: 50%;\">\u5352\u696d\u5e74\u5ea6<\/td>\n<td style=\"width: 50%;\">\u5e73\u62106\u5e74<\/td>\n<\/tr>\n<tr>\n<td style=\"width: 50%;\">\u5c02\u9580\u9818\u57df<\/td>\n<td style=\"width: 50%;\">\u52d5\u8108\u786c\u5316\u3001\u7cd6\u5c3f\u75c5\u3001\u9ad8\u8840\u5727\u3001\u8102\u8cea\u4ee3\u8b1d\u7570\u5e38 (\u30e1\u30bf\u30dc\u30ea\u30c3\u30af\u75c7\u5019\u7fa4)\u3001\u7cd6\u5c3f\u75c5\u814e\u75c7 (\u65e5\u672c\u7cd6\u5c3f\u75c5\u5b66\u4f1a\u5c02\u9580\u533b\u3001\u65e5\u672c\u5185\u79d1\u5b66\u4f1a\u8a8d\u5b9a\u7dcf\u5408\u5185\u79d1\u5c02\u9580\u533b\u3001\u540c\u8a8d\u5b9a\u533b\u3001\u540c\u7814\u4fee\u6307\u5c0e\u533b\u3001\u65e5\u672c\u5faa\u74b0\u5668\u5b66\u4f1a\u5c02\u9580\u533b\u3001\u65e5\u672c\u814e\u81d3\u75c5\u5b66\u4f1a\u5c02\u9580\u533b\u3001\u65e5\u672c\u9ad8\u8840\u5727\u5b66\u4f1a\u5c02\u9580\u533b\u3001\u540c\u6307\u5c0e\u533b)<\/td>\n<\/tr>\n<tr>\n<td style=\"width: 50%;\">\u81ea\u5df1\u7d39\u4ecb<\/td>\n<td style=\"width: 50%;\">\u52d5\u8108\u786c\u5316\u3092\u5c02\u9580\u306b\u3057\u3066\u304a\u308a\u7cd6\u5c3f\u75c5\u3092\u7cd6\u4ee3\u8b1d\u7570\u5e38\u306e\u307f\u306a\u3089\u305a\u8840\u7ba1\u75c5\u3068\u3057\u3066\u3068\u3089\u3048\u8a3a\u7642\u3057\u3066\u304a\u308a\u307e\u3059\u3002\u7cd6\u5c3f\u75c5\u306b\u3088\u308b\u52d5\u8108\u786c\u5316\u3084\u5fc3\u4e0d\u5168\u306e\u7814\u7a76\u3092\u884c\u3063\u3066\u304a\u308a\u307e\u3059\u3002\u9ad8\u8840\u5727\u3084\u8102\u8cea\u4ee3\u8b1d\u7570\u5e38\u3092\u4f34\u3046\u7cd6\u5c3f\u75c5\u3001\u5fc3\u8840\u7ba1\u5408\u4f75\u75c7\u3092\u4f34\u3046\u7cd6\u5c3f\u75c5\u3001\u7cd6\u5c3f\u75c5\u6027\u814e\u75c7\u306a\u3069\u306e\u60a3\u8005\u3055\u3093\u304c\u3044\u3089\u3063\u3057\u3083\u3044\u307e\u3057\u305f\u3089\u3054\u7d39\u4ecb\u304f\u3060\u3055\u3044\u3002<\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n<p>&nbsp;<\/p>\n<table style=\"border-collapse: collapse; width: 100%;\">\n<tbody>\n<tr>\n<td style=\"width: 50%;\">\u6c0f\u540d<\/td>\n<td style=\"width: 50%;\">\u5ddd\u6751\u3000\u826f\u4e00 (\u304b\u308f\u3080\u3089\u3000\u308a\u3087\u3046\u3044\u3061)<\/td>\n<\/tr>\n<tr>\n<td style=\"width: 50%;\">\u5f79\u8077<\/td>\n<td style=\"width: 50%;\">\u7279\u4efb\u8b1b\u5e2b<\/td>\n<\/tr>\n<tr>\n<td style=\"width: 50%;\">\u6240\u5c5e\u8b1b\u5ea7<\/td>\n<td style=\"width: 50%;\">\u611b\u5a9b\u5927\u5b66\u5927\u5b66\u9662\u7cd6\u5c3f\u75c5\u5185\u79d1\u5b66\u8b1b\u5ea7<\/td>\n<\/tr>\n<tr>\n<td style=\"width: 50%;\">\u5352\u696d\u5e74\u5ea6<\/td>\n<td style=\"width: 50%;\">\u5e73\u621015\u5e74<\/td>\n<\/tr>\n<tr>\n<td style=\"width: 50%;\">\u5c02\u9580\u9818\u57df<\/td>\n<td style=\"width: 50%;\">\u7cd6\u5c3f\u75c5 (\u65e5\u672c\u5185\u79d1\u5b66\u4f1a\u7dcf\u5408\u5185\u79d1\u5c02\u9580\u533b\u3001\u540c\u7814\u4fee\u6307\u5c0e\u533b)\u3001\u65e5\u672c\u7cd6\u5c3f\u75c5\u5b66\u4f1a\u5c02\u9580\u533b<\/td>\n<\/tr>\n<tr>\n<td style=\"width: 50%;\">\u81ea\u5df1\u7d39\u4ecb<\/td>\n<td style=\"width: 50%;\">\u7cd6\u5c3f\u75c5\u3092\u5c02\u9580\u306b\u5916\u6765\u8a3a\u7642\u3092\u884c\u3063\u3066\u3044\u307e\u3059\u3002\u307e\u305f\u3001\u5468\u8853\u671f\u3084\u30b9\u30c6\u30ed\u30a4\u30c9\u6295\u4e0e\u6642\u3001\u9ad8\u30ab\u30ed\u30ea\u30fc\u8f38\u6db2\u6642\u306e\u8840\u7cd6\u7ba1\u7406\u306b\u3082\u5bfe\u5fdc\u3044\u305f\u3057\u307e\u3059\u306e\u3067\u3001\u5fa1\u7d39\u4ecb\u3044\u305f\u3060\u3051\u307e\u3057\u305f\u3089\u5e78\u3044\u3067\u3059\u3002<\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n<table style=\"border-collapse: collapse; width: 100%;\">\n<tbody>\n<tr>\n<td style=\"width: 50%;\">\u6c0f\u540d<\/td>\n<td style=\"width: 50%;\">\u6c60\u7530\u3000\u967d\u4ecb (\u3044\u3051\u3060\u3000\u3088\u3046\u3059\u3051)<\/td>\n<\/tr>\n<tr>\n<td style=\"width: 50%;\">\u5f79\u8077<\/td>\n<td style=\"width: 50%;\">\u52a9\u6559<\/td>\n<\/tr>\n<tr>\n<td style=\"width: 50%;\">\u6240\u5c5e\u8b1b\u5ea7<\/td>\n<td style=\"width: 50%;\">\u611b\u5a9b\u5927\u5b66\u5927\u5b66\u9662\u7cd6\u5c3f\u75c5\u5185\u79d1\u5b66\u8b1b\u5ea7 (\u691c\u67fb\u90e8)<\/td>\n<\/tr>\n<tr>\n<td style=\"width: 50%;\">\u5352\u696d\u5e74\u5ea6<\/td>\n<td style=\"width: 50%;\">\u5e73\u621023\u5e74<\/td>\n<\/tr>\n<tr>\n<td style=\"width: 50%;\">\u5c02\u9580\u9818\u57df<\/td>\n<td style=\"width: 50%;\">\u65e5\u672c\u5185\u79d1\u5b66\u4f1a\u8a8d\u5b9a\u5185\u79d1\u533b\u30fb\u540c\u7814\u4fee\u6307\u5c0e\u533b\u3001\u65e5\u672c\u7cd6\u5c3f\u75c5\u5b66\u4f1a\u5c02\u9580\u533b\u3001\u65e5\u672c\u5185\u5206\u6ccc\u5b66\u4f1a\u5c02\u9580\u533b<\/td>\n<\/tr>\n<tr>\n<td style=\"width: 50%;\">\u81ea\u5df1\u7d39\u4ecb<\/td>\n<td style=\"width: 50%;\">\u7cd6\u5c3f\u75c5\u3092\u5c02<span class=\"il\">\u9580<\/span>\u306b\u5916\u6765\u8a3a\u7642\u3092\u884c\u3063\u3066\u304a\u308a\u307e\u3059\u3002\u7cd6\u5c3f\u75c5\u306e\u307f\u306a\u3089\u305a\u3001<wbr \/><span class=\"il\">\u9ad8<\/span>\u8840\u5727\u3001\u8102\u8cea\u7570\u5e38\u75c7\u3001\u80a5\u6e80\u3001<wbr \/>\u30b5\u30eb\u30b3\u30da\u30cb\u30a2\u3092\u542b\u3081\u305f\u751f\u6d3b\u7fd2\u6163\u75c5\u306e\u5305\u62ec\u7684\u7ba1\u7406\u3092\u76ee\u6307\u3057\u3066\u304a\u308a\u307e\u3059<wbr \/>\u306e\u3067\u3001\u3053\u308c\u3089<wbr \/>\u5408\u4f75\u75c7\u3092\u62b1\u3048\u308b\u60a3\u8005\u69d8\u304c\u3044\u3089\u3063\u3057\u3083\u3044\u307e\u3057\u305f\u3089\u662f\u975e\u3054\u7d39\u4ecb\u4e0b\u3055\u3044\u3002<\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n<table style=\"border-collapse: collapse; width: 100%;\">\n<tbody>\n<tr>\n<td style=\"width: 50%;\">\u6c0f\u540d<\/td>\n<td style=\"width: 50%;\">\u9ad8\u9580\u3000\u7f8e\u6c99\u5b63 (\u305f\u304b\u304b\u3069\u3000\u307f\u3055\u304d)<\/td>\n<\/tr>\n<tr>\n<td style=\"width: 50%;\">\u5f79\u8077<\/td>\n<td style=\"width: 50%;\">\u52a9\u6559<\/td>\n<\/tr>\n<tr>\n<td style=\"width: 50%;\">\u6240\u5c5e\u8b1b\u5ea7<\/td>\n<td style=\"width: 50%;\">\u611b\u5a9b\u5927\u5b66\u5927\u5b66\u9662\u7cd6\u5c3f\u75c5\u5185\u79d1\u5b66\u8b1b\u5ea7 (\u691c\u67fb\u90e8)<\/td>\n<\/tr>\n<tr>\n<td style=\"width: 50%;\">\u5352\u696d\u5e74\u5ea6<\/td>\n<td style=\"width: 50%;\">\u5e73\u621026\u5e74<\/td>\n<\/tr>\n<tr>\n<td style=\"width: 50%;\">\u5c02\u9580\u9818\u57df<\/td>\n<td style=\"width: 50%;\">\u65e5\u672c\u5185\u79d1\u5b66\u4f1a\u8a8d\u5b9a\u5185\u79d1\u533b\u3001\u65e5\u672c\u7cd6\u5c3f\u75c5\u5b66\u4f1a\u5c02\u9580\u533b\u3001\u65e5\u672c\u5c02\u9580\u533b\u6a5f\u69cb\u8a8d\u5b9a\u81e8\u5e8a\u691c\u67fb\u5c02\u9580\u533b\u3001\u65e5\u672c\u81e8\u5e8a\u691c\u67fb\u533b\u5b66\u4f1a\u81e8\u5e8a\u691c\u67fb\u7ba1\u7406\u533b<\/td>\n<\/tr>\n<tr>\n<td style=\"width: 50%;\">\u81ea\u5df1\u7d39\u4ecb<\/td>\n<td style=\"width: 50%;\">\u3088\u308d\u3057\u304f\u304a\u9858\u3044\u81f4\u3057\u307e\u3059\u3002<\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n<table style=\"border-collapse: collapse; width: 100%;\">\n<tbody>\n<tr>\n<td style=\"width: 50%;\">\u6c0f\u540d<\/td>\n<td style=\"width: 50%;\">\u7fbd\u7acb\u3000\u767b\u5fd7\u7f8e (\u306f\u3060\u3066\u3000\u3068\u3057\u307f)<\/td>\n<\/tr>\n<tr>\n<td style=\"width: 50%;\">\u5f79\u8077<\/td>\n<td style=\"width: 50%;\">\u533b\u5e2b<\/td>\n<\/tr>\n<tr>\n<td style=\"width: 50%;\">\u6240\u5c5e\u8b1b\u5ea7<\/td>\n<td style=\"width: 50%;\">\u611b\u5a9b\u5927\u5b66\u5927\u5b66\u9662\u7cd6\u5c3f\u75c5\u5185\u79d1\u5b66\u8b1b\u5ea7 (\u691c\u67fb\u90e8)<\/td>\n<\/tr>\n<tr>\n<td style=\"width: 50%;\">\u5352\u696d\u5e74\u5ea6<\/td>\n<td style=\"width: 50%;\">\u5e73\u621022\u5e74<\/td>\n<\/tr>\n<tr>\n<td style=\"width: 50%;\">\u5c02\u9580\u9818\u57df<\/td>\n<td style=\"width: 50%;\">\u65e5\u672c\u5185\u79d1\u5b66\u4f1a\u7dcf\u5408\u5185\u79d1\u5c02\u9580\u533b\u3001\u65e5\u672c\u7cd6\u5c3f\u75c5\u5b66\u4f1a\u5c02\u9580\u533b<\/td>\n<\/tr>\n<tr>\n<td style=\"width: 50%;\">\u81ea\u5df1\u7d39\u4ecb<\/td>\n<td style=\"width: 50%;\">\u3088\u308d\u3057\u304f\u304a\u9858\u3044\u81f4\u3057\u307e\u3059\u3002<\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n<table style=\"border-collapse: collapse; width: 100%;\">\n<tbody>\n<tr>\n<td style=\"width: 50%;\">\u6c0f\u540d<\/td>\n<td style=\"width: 50%;\">\u6797\u3000\u667a\u91cc (\u306f\u3084\u3057\u3000\u3061\u3055\u3068)<\/td>\n<\/tr>\n<tr>\n<td style=\"width: 50%;\">\u5f79\u8077<\/td>\n<td style=\"width: 50%;\">\u533b\u5e2b<\/td>\n<\/tr>\n<tr>\n<td style=\"width: 50%;\">\u6240\u5c5e\u8b1b\u5ea7<\/td>\n<td style=\"width: 50%;\">\u611b\u5a9b\u5927\u5b66\u5927\u5b66\u9662\u7cd6\u5c3f\u75c5\u5185\u79d1\u5b66\u8b1b\u5ea7 (\u691c\u67fb\u90e8)<\/td>\n<\/tr>\n<tr>\n<td style=\"width: 50%;\">\u5352\u696d\u5e74\u5ea6<\/td>\n<td style=\"width: 50%;\">\u5e73\u621028\u5e74<\/td>\n<\/tr>\n<tr>\n<td style=\"width: 50%;\">\u5c02\u9580\u9818\u57df<\/td>\n<td style=\"width: 50%;\">\u65e5\u672c\u5c02\u9580\u533b\u6a5f\u69cb\u8a8d\u5b9a 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