{"id":2097,"date":"2018-08-17T13:21:49","date_gmt":"2018-08-17T04:21:49","guid":{"rendered":"https:\/\/www.m.ehime-u.ac.jp\/school\/int.med1\/?page_id=2097"},"modified":"2024-01-16T15:44:03","modified_gmt":"2024-01-16T06:44:03","slug":"research-detail-2","status":"publish","type":"page","link":"https:\/\/www.m.ehime-u.ac.jp\/school\/int.med1\/?page_id=2097","title":{"rendered":"\u7814\u7a76\u5185\u5bb9"},"content":{"rendered":"<div id=\"about-research\">\n<p>\u7814\u7a76\u9762\u3067\u306f\u3001\u8840\u6db2\u3001\u611f\u67d3\u75c7\u3001\u81ea\u5df1\u514d\u75ab\u75be\u60a3\u306a\u3069\u3092\u4e3b\u306a\u7814\u7a76\u5bfe\u8c61\u3068\u3057\u3066\u304a\u308a\u3001\u5206\u5b50\u30fb\u7d30\u80de\u751f\u7269\u5b66\u3001\u514d\u75ab\u5b66\u3001\u907a\u4f1d\u5b66\u3001\u751f\u5316\u5b66\u7684\u306a\u5074\u9762\u304b\u3089\u691c\u8a0e\u3092\u52a0\u3048\u3066\u3044\u307e\u3059\u3002<\/p>\n<p>\u81e8\u5e8a\u306e\u5834\u3067\u906d\u9047\u3057\u305f\u554f\u984c\u70b9\u3084\u7591\u554f\u3092\u30c6\u30fc\u30de\u306b\u3057\u305f\u7814\u7a76\u3092\u5c55\u958b\u3057\u3066\u304a\u308a\u3001\u7814\u7a76\u6210\u679c\u3092\u81e8\u5e8a\u306e\u5834\u306b\u9084\u5143\u3057\u3001\u6cbb\u7642\u6210\u7e3e\u306e\u5411\u4e0a\u306b\u8ca2\u732e\u3067\u304d\u308b\u7814\u7a76\u3092\u76ee\u6307\u3057\u3066\u3044\u307e\u3059\u3002 \u7814\u7a76\u6210\u679c\u306f\u56fd\u5185\u5916\u306e\u5b66\u4f1a\u3067\u767a\u8868\u3059\u308b\u3068\u3068\u3082\u306b\u3001\u6a29\u5a01\u3042\u308b\u56fd\u969b\u8a8c\u306b\u8ad6\u6587\u3092\u767a\u8868\u3059\u308b\u3088\u3046\u306b\u5fc3\u639b\u3051\u3066\u304a\u308a\u3001\u611b\u5a9b\u304b\u3089\u4e16\u754c\u306b\u767a\u4fe1\u3067\u304d\u308b\u7814\u7a76\u6210\u679c\u304c\u5f97\u3089\u308c\u308b\u3088\u3046\u52aa\u529b\u3057\u3066\u3044\u307e\u3059\u3002<\/p>\n<p>\u3053\u308c\u307e\u3067\u306e\u7814\u7a76\u6210\u679c\u306f\u696d\u7e3e\u6b04\u3092\u53c2\u7167\u3057\u3066\u304f\u3060\u3055\u3044\u3002<\/p>\n<div class=\"about-research\">\n<div class=\"about-research-inner2\">\n<h3 class=\"study\">\u60a3\u8005\u7d44\u7e54\u79fb\u690d\u30e2\u30c7\u30eb\u958b\u767a\u306b\u3088\u308b<br \/>\u5168\u822c\u7684\u75be\u60a3\u30e2\u30c7\u30eb\u69cb\u7bc9\u304b\u3089\u816b\u760d\u5e79\u7d30\u80de\u7d14\u5316\u3068\u5275\u85ac\u958b\u767a\u652f\u63f4<br \/>\n<span>Cancer stem cell purification and drug discovery support by the overall disease model using a new PDX model<\/span><br \/>\n<\/h3>\n<\/div>\n<\/div>\n<div class=\"about-research\">\n<\/div>\n<\/div>\n<p><del datetime=\"2015-07-06T07:53:21+00:00\"><\/p>\n<div id=\"research-detail\">\n<div class=\"research-detail1\">\n<div class=\"research-detail1-inner2\">\n<div class=\"pc-only\"><img decoding=\"async\" src=\"\/school\/int.med1\/wordpress\/img\/pages\/img-research_bg.jpg\" alt=\"\" class=\"pc-only\"\/><\/div>\n<p>\u30d2\u30c8\u6b63\u5e38\u9020\u8840\u5e79\u7d30\u80de\u306e\u30a2\u30c3\u30bb\u30a4\u7cfb\u3068\u3057\u3066\u958b\u767a\u3055\u308c\u305f\u514d\u75ab\u4e0d\u5168\u30de\u30a6\u30b9\u306b\u3088\u308b\u7570\u7a2e\u79fb\u690d\u306e\u7cfb\u306f\u3001\u816b\u760d\u6027\u5e79\u7d30\u80de\u7814\u7a76\u3084\u60a3\u8005\u816b\u760d\u7d44\u7e54\u79fb\u690d\u30e2\u30c7\u30eb\u306b\u3088\u308b\u6297\u304c\u3093\u5264\u306e\u6cbb\u7642\u52b9\u679c\u4e88\u6e2c\u3078\u306e\u5fdc\u7528\u304c\u671f\u5f85\u3055\u308c\u3066\u3044\u307e\u3059\u3002\u3055\u3089\u306b\u3001\u591a\u69d8\u306a\u304c\u3093\u514d\u75ab\u7642\u6cd5\u306e\u958b\u767a\u904e\u7a0b\u3067\u3001\u30de\u30a6\u30b9\u5185\u3067\u30d2\u30c8\u9020\u8840\u7cfb\u3092\u518d\u69cb\u7bc9\u3057\u305f\u30d2\u30c8\u5316\u30de\u30a6\u30b9\u3092\u30d9\u30fc\u30b9\u306b\u3001\u30d2\u30c8\u514d\u75ab\u7cfb\u3068\u816b\u760d\u306e\u76f8\u4e92\u4f5c\u7528\u3092\u518d\u73fe\u3057\u3001\u30d2\u30c8\u7279\u7570\u7684\u514d\u75ab\u7642\u6cd5\u3092in vivo\u3067\u8a55\u4fa1\u53ef\u80fd\u306a\u524d\u81e8\u5e8a\u30e2\u30c7\u30eb\u306e\u958b\u767a\u3082\u6c42\u3081\u3089\u308c\u3066\u3044\u307e\u3059\u3002\u3057\u304b\u3057\u3001\u3053\u306e\u5206\u91ce\u3078\u306e\u5c55\u958b\u306b\u306f\u3001\u300c\u30d2\u30c8\u5316\u30de\u30a6\u30b9\u306b\u304a\u3051\u308b\u30d2\u30c8\u816b\u760d\u306e\u5168\u822c\u7684\u751f\u7740\u52b9\u7387\u306e\u5411\u4e0a\u300d\u3068\u300c\u81f3\u9069\u304c\u3093\u514d\u75ab\u7642\u6cd5\u8a55\u4fa1\u30e2\u30c7\u30eb\u306e\u69cb\u7bc9\u300d\u304c\u5fc5\u9808\u3067\u3059\u3002\u672c\u7814\u7a76\u3067\u306f\u3001\u3053\u308c\u3089\u306e\u554f\u984c\u70b9\u3092\u514b\u670d\u3059\u308b\u305f\u3081\u3001\u6211\u3005\u304c\u72ec\u81ea\u306b\u958b\u767a\u3057\u305f\u30d2\u30c8\u5316\u30de\u30a6\u30b9\u3068\u30ad\u30e1\u30e9\u6297\u539f\u53d7\u5bb9\u4f53\u907a\u4f1d\u5b50\u6539\u5909\u6280\u8853\u3092\u7d44\u307f\u5408\u308f\u305b\u3001\u514d\u75ab\u816b\u760d\u5b66\u5206\u91ce\u306b\u304a\u3051\u308b\u6b21\u4e16\u4ee3\u30d2\u30c8\u5316\u30de\u30a6\u30b9\u60a3\u8005\u816b\u760d\u7d44\u7e54\u79fb\u690d\u30e2\u30c7\u30eb\u30d7\u30e9\u30c3\u30c8\u30d5\u30a9\u30fc\u30e0\u3092\u6a39\u7acb\u3057\u3001\u304c\u3093\u514d\u75ab\u5275\u85ac\u958b\u767a\u3092\u652f\u63f4\u3059\u308b\u57fa\u76e4\u7684\u6280\u8853\u306e\u78ba\u7acb\u3092\u76ee\u6307\u3057\u3066\u3044\u307e\u3059\u3002<br \/>\n<supan>\uff08\u7af9\u4e2d\u514b\u6597\uff09<\/supan>\n<\/p>\n<\/div>\n<p><img decoding=\"async\" src=\".\/wordpress\/wp-content\/uploads\/2024\/01\/2024-01-05-12.52.36-1024x579.png\"\/><\/p>\n<div class=\"sp-only\"><img decoding=\"async\" src=\"\/school\/int.med1\/wordpress\/img\/pages\/img-research_bg_sp.jpg\" alt=\"\" \/><\/div>\n<div class=\"research-detail1-inner2\">\n<h3>\u9020\u8840\u5668\u816b\u760d\u306b\u5bfe\u3059\u308b\u514d\u75ab\u7642\u6cd5<br \/>\n-Bedside \u21d4 Bench-<br \/>\n<span>Development of immunotherapy for hematologic malignancies<\/span><br \/>\n<\/h3>\n<\/div>\n<\/div>\n<div class=\"research-detail2\"><img decoding=\"async\" src=\".\/wordpress\/wp-content\/uploads\/2015\/06\/img-research1.jpg\" alt=\"\" \/><\/p>\n<p class=\"inp5\">\u9020\u8840\u5668\u816b\u760d\u306b\u5bfe\u3059\u308b\u4e3b\u306a\u6cbb\u7642\u6cd5\u3068\u3057\u3066\u3001\u6297\u304c\u3093\u5264\u6cbb\u7642 (\u5316\u5b66\u7642\u6cd5)\u30fb\u653e\u5c04\u7dda\u6cbb\u7642\u30fb\u9020\u8840\u5e79\u7d30\u80de\u79fb\u690d\u6cbb\u7642\u304c\u3088\u304f\u77e5\u3089\u308c\u3066\u3044\u307e\u3059\u3002\u9020\u8840\u5668\u816b\u760d\u306f\u3001\u9032\u884c\u3057\u305f\u816b\u760d\u3067\u3042\u3063\u305f\u3068\u3057\u3066\u3082\u6cbb\u7652\u3059\u308b\u53ef\u80fd\u6027\u304c\u9ad8\u3044\u3053\u3068\u304c\u5927\u304d\u306a\u7279\u5fb4\u306e1\u3064\u3067\u3042\u308a\u307e\u3059\u304c\u3001\u3084\u306f\u308a\u518d\u767a\u96e3\u6cbb\u4f8b\u3082\u591a\u304f\u7d4c\u9a13\u3055\u308c\u307e\u3059\u3002\u305d\u306e\u4e2d\u3067\u3001\u3053\u306e15\u5e74\u307b\u3069\u3067\u65b0\u305f\u306b\u958b\u767a\u3055\u308c\u3066\u304d\u305f\u514d\u75ab\u7642\u6cd5\u306b\u6ce8\u76ee\u304c\u96c6\u307e\u308b\u3088\u3046\u306b\u306a\u308a\u307e\u3057\u305f\u3002\u4f8b\u3048\u3070\u3001\u6210\u5206\u63a1\u8840\u88c5\u7f6e\u3092\u7528\u3044\u3066\u60a3\u8005\u69d8\u304b\u3089\u30ea\u30f3\u30d1\u7403\u3092\u63a1\u53d6\u3057\u305f\u3042\u3068\u3001\u30ad\u30e1\u30e9\u6297\u539f\u53d7\u5bb9\u4f53 (CAR: Chimeric Antigen Receptor)\u3000\u3068\u3088\u3070\u308c\u308b\u4eba\u5de5\u7684\u306a\u907a\u4f1d\u5b50\u3092T\u7d30\u80de\u306b\u5c0e\u5165\u3057\u3066CAR-T\u7d30\u80de\u3092\u4f5c\u88fd\u3057\u3001\u60a3\u8005\u69d8\u306b\u8f38\u6ce8\u3057\u3066\u6cbb\u7642\u3059\u308bCAR-T\u7d30\u80de\u7642\u6cd5 (\u518d\u751f\u533b\u7642\u7b49\u88fd\u54c1) \u3084\u3001\u907a\u4f1d\u5b50\u6539\u5909\u6280\u8853\u3092\u99c6\u4f7f\u3057\u3066\u4f5c\u88fd\u3055\u308c\u305f\u6297\u4f53\u533b\u85ac\u54c1\u3067\u3042\u308b\u4e8c\u91cd\u7279\u7570\u6027\u6297\u4f53\u7642\u6cd5 (BsAb: Bispecific Antibody) \u306a\u3069\u304c\u6319\u3052\u3089\u308c\u307e\u3059\u3002\u75c5\u72b6\u306b\u3082\u3088\u308a\u307e\u3059\u304c\u3001\u518d\u767a\u96e3\u6cbb\u4f8b\u306e\u7d04\u534a\u6570\u306e\u60a3\u8005\u69d8\u306b\u304a\u3044\u3066\u6cbb\u7642\u52b9\u679c\u304c\u671f\u5f85\u3067\u304d\u308b\u3053\u3068\u304b\u3089\u3001\u56fd\u5185\u3067\u3082\u4fdd\u967a\u53ce\u8f09\u3055\u308c\u5b9f\u81e8\u5e8a\u3067\u76db\u3093\u306b\u4f7f\u7528\u3055\u308c\u308b\u3088\u3046\u306b\u306a\u308a\u307e\u3057\u305f\u3002\u305d\u306e\u4e00\u65b9\u3067\u3001\u30b5\u30a4\u30c8\u30ab\u30a4\u30f3\u653e\u51fa\u75c7\u5019\u7fa4 (CRS: Cytokine Release Syndrome) \u306a\u3069\u306e\u514d\u75ab\u7642\u6cd5\u306b\u7e8f\u308f\u308b\u7279\u6709\u306e\u5408\u4f75\u75c7\u306b\u6ce8\u610f\u3092\u6255\u3046\u5fc5\u8981\u6027\u304c\u3042\u308b\u3053\u3068\u3082\u660e\u3089\u304b\u3068\u306a\u308a\u307e\u3057\u305f\u3002<br \/>\n\u5f53\u9662\u306f\u611b\u5a9b\u770c\u5185\u3067\u552f\u4e00\u306eCAR-T\u7d30\u80de\u7642\u6cd5\u8a3a\u7642\u65bd\u8a2d\u3067\u3042\u308a\u3001\u5f53\u79d1\u3067\u306f\u518d\u767a\u96e3\u6cbb\u3067\u3042\u308bB\u7d30\u80de\u60aa\u6027\u30ea\u30f3\u30d1\u816b\u306e\u60a3\u8005\u69d8\u306eCAR-T\u6cbb\u7642\u306b\u53d6\u308a\u7d44\u3093\u3067\u3044\u307e\u3059\u304c\u3001\u3053\u308c\u304b\u3089\u306e\u304c\u3093\u514d\u75ab\u7642\u6cd5\u306b\u306f\u3001\u300c\u3069\u306e\u3088\u3046\u306b\u3059\u308c\u3070\u5b89\u5168\u306b\u9ad8\u3044\u6cbb\u7642\u52b9\u679c\u3092\u8a98\u5c0e\u3067\u304d\u308b\u304b\u300d\u304c\u91cd\u8981\u306a\u8ab2\u984c\u3068\u3057\u3066\u6c42\u3081\u3089\u308c\u3066\u3044\u307e\u3059\u3002\u307e\u305f\u3001\u4f53\u5185\u3067\u816b\u760d\u3092\u653b\u6483\u3057\u3064\u3064\u9577\u751f\u304d\u3067\u304d\u308bCAR-T\u7d30\u80de\u3092\u4f5c\u88fd\u3059\u308b\u6280\u8853\u958b\u767a\u3084\u3001\u6a19\u7684\u3068\u306a\u308b\u6297\u539f\u3092\u9650\u5b9a\u3057\u306a\u3044\u6c4e\u7528\u6027\u306e\u9ad8\u3044BsAb\u306e\u958b\u767a\u306a\u3069\u3082\u6c42\u3081\u3089\u308c\u3066\u3044\u307e\u3059\u3002\u6211\u3005\u306e\u7814\u7a76\u30b0\u30eb\u30fc\u30d7\u3067\u306f\u3001\u3053\u308c\u307e\u3067\u306b\u907a\u4f1d\u5b50\u6539\u5909\u6280\u8853\u3092\u5fdc\u7528\u3057\u3066\u3001CAR-T\u7d30\u80de\u3068BsAb\u306e\u6cbb\u7642\u52b9\u679c\u306e\u7279\u5fb4\u3084\u9055\u3044\u3092\u6bd4\u8f03\u89e3\u6790\u3057 (Maruta M, et al. Sci Rep, 2019)\u3001CAR-T\u7d30\u80de\u304c\u816b\u760d\u7d30\u80de\u3092\u8a8d\u8b58\u3059\u308b\u305f\u3081\u306b\u91cd\u8981\u306a\u4e00\u672c\u9396\u6297\u4f53 (scFv) \u3092\u81ea\u7531\u306b\u6539\u5909\u3059\u308b\u3053\u3068\u3067\u3001\u9ad8\u3044\u6cbb\u7642\u52b9\u679c\u3092\u3082\u3064CAR-T\u7d30\u80de\u3092\u7db2\u7f85\u7684\u306b\u4f5c\u308a\u51fa\u3059\u6280\u8853\u3092\u958b\u767a\u3057\u3066\u304d\u307e\u3057\u305f (Ochi T, et al. Commun Biol, 2021)\u3002\u305d\u3057\u3066\u3001\u611b\u5a9b\u5927\u5b66\u533b\u5b66\u90e8\u304b\u3089Optieum Biotechnologies\u682a\u5f0f\u4f1a\u793e\u3092\u8a2d\u7acb\u3057\u3001\u6211\u3005\u306e\u6280\u8853\u3092\u65b0\u305f\u306aCAR-T\u5275\u85ac\u306b\u7e4b\u3044\u3067\u3044\u304f\u305f\u3081\u306b\u5171\u540c\u7814\u7a76\u3082\u884c\u3063\u3066\u3044\u307e\u3059\u3002\u3055\u3089\u306b\u3001\u5b9f\u81e8\u5e8a\u3067\u7528\u3044\u3089\u308c\u3066\u3044\u308b\u6297\u4f53\u533b\u85ac\u54c1\u306b\u7d50\u5408\u3055\u305b\u3066\u4f7f\u7528\u3059\u308bB-BiTE\u3068\u547c\u3070\u308c\u308b\u65b0\u305f\u306a\u30e2\u30c0\u30ea\u30c6\u30a3\u3092\u5275\u51fa\u3057\u3001\u8907\u5408\u7684\u306b\u30ea\u30f3\u30d1\u7403\u3092\u6d3b\u6027\u5316\u3067\u304d\u308b\u591a\u6570\u306e\u65b0\u578bBsAb\u3092\u7c21\u5358\u306b\u4f5c\u308a\u51fa\u3059\u3053\u3068\u306b\u3082\u6210\u529f\u3057\u3066\u3001\u4e16\u754c\u7684\u306b\u3082\u6ce8\u76ee\u3055\u308c\u3066\u3044\u307e\u3059 (Konishi T, et al. Blood, 2023)\u3002\u3053\u306e\u3088\u3046\u306b\u6211\u3005\u306e\u30b0\u30eb\u30fc\u30d7\u306f\u3001\u60a3\u8005\u69d8\u306e\u6cbb\u7642\u3092\u901a\u3057\u3066\u5b66\u3070\u305b\u3066\u3044\u305f\u3060\u3044\u305f\u3053\u3068\u3092\u3001\u6b21\u4e16\u4ee3\u578b\u514d\u75ab\u7642\u6cd5\u306e\u958b\u767a\u305d\u3057\u3066\u65b0\u305f\u306a\u6cbb\u7642\u306e\u78ba\u7acb\u306b\u7e4b\u3052\u308b\u3053\u3068\u3092\u76ee\u6a19\u306b\u3057\u3066\u3044\u307e\u3059\u3002\u6700\u5148\u7aef\u306e\u7814\u7a76\u6210\u679c\u3092\u611b\u5a9b\u304b\u3089\u4e16\u754c\u306b\u5411\u3051\u3066\u767a\u4fe1\u3057\u3001\u4e00\u523b\u3082\u65e9\u304f\u60a3\u8005\u69d8\u306b\u9084\u5143\u3067\u304d\u308b\u3088\u3046\u3001\u65e5\u3005\u81e8\u5e8a\u3068\u7814\u7a76\u306b\u53d6\u308a\u7d44\u3093\u3067\u3044\u307e\u3059\u3002<br \/>\n<supan>\uff08\u8d8a\u667a\u4fca\u5143\uff09<\/supan><br \/>\n<B>\u3010CAR-T\u7642\u6cd5\u306b\u3064\u3044\u3066\u306f\u3053\u3061\u3089\u3011<\/B><br \/>\n<span style=\"color: #0000ff;\"><a style=\"color: #0000ff;\" href=\"https:\/\/www.m.ehime-u.ac.jp\/school\/int.med1\/?p=4225\">\u60a3\u8005\u69d8\u5411\u3051<\/a><\/span><br \/>\n<span style=\"color: #0000ff;\"><a style=\"color: #0000ff;\" href=\"https:\/\/www.m.ehime-u.ac.jp\/school\/int.med1\/?p=4233\">\u533b\u7642\u6a5f\u95a2\u5411\u3051<\/a><\/span><\/p>\n<\/div>\n<p class=\"pagetop\"><a href=\"#\">PAGE TOP<\/a><\/p>\n<div class=\"research-detail3\">\n<h3>\u8840\u6813\u6b62\u8840\u9818\u57df   <span>Thrombosis and Hemostasis area<\/span><\/h3>\n<div><img decoding=\"async\" src=\".\/wordpress\/wp-content\/uploads\/2015\/06\/img-research2.jpg\" alt=\"\" \/><\/div>\n<div class=\"research-detail3-inner\">\n<p>\u8840\u5c0f\u677f\u306f\u51fa\u8840\u306b\u5bfe\u3059\u308b\u751f\u4f53\u9632\u5fa1\u53cd\u5fdc\u3068\u3057\u3066\u306e\u751f\u7406\u7684\u6b62\u8840\u8840\u6813\u3068\u3001\u8840\u7ba1\u5185\u8154\u3092\u9589\u585e\u3057\u8133\u6897\u585e\u30fb\u5fc3\u7b4b\u6897\u585e\u306a\u3069\u306e\u8840\u6813\u75c7\u3092\u62db\u6765\u3059\u308b\u75c5\u7684\u8840\u6813\u306e\u5f62\u6210\u306b\u6df1\u304f\u95a2\u4e0e\u3057\u3066\u3044\u308b\u3002\u79c1\u3069\u3082\u306f\u75c5\u7684\u8840\u5c0f\u677f\u8840\u6813\u5f62\u6210\u6a5f\u5e8f\u306e\u89e3\u660e\u3068\u305d\u306e\u5236\u5fa1\u624b\u6bb5\u306e\u958b\u767a\u3092\u3081\u3056\u3057\u3066\u3044\u308b\u3002\u7279\u306b\u3001\u8840\u5c0f\u677f\u8868\u9762\u306b\u3042\u308b\u7c98\u7740\u86cb\u767d\u30ec\u30bb\u30d7\u30bf\u30fc\u306e\u6a5f\u80fd\u306b\u7126\u70b9\u3092\u5f53\u3066\u3001\u907a\u4f1d\u5b50\u5de5\u5b66\u7684\u624b\u6bb5\u3092\u7528\u3044\u3066\u305d\u306e\u30ec\u30bb\u30d7\u30bf\u30fc\u306e\u6d3b\u6027\u5316\u6a5f\u69cb\u3092\u691c\u8a0e\u3057\u3066\u3044\u308b\u3002\u305d\u306e\u7d50\u679c\u3001\u30ec\u30bb\u30d7\u30bf\u30fc\u6a5f\u80fd\u306e\u767a\u73fe\u306b\u91cd\u8981\u306a\u90e8\u4f4d\u306e\u3044\u304f\u3064\u304b\u3092\u5206\u5b50\u30ec\u30d9\u30eb\u3067\u540c\u5b9a\u3057\u305f\u3002\u3053\u308c\u3089\u306e\u90e8\u4f4d\u304c\u6a5f\u80fd\u3092\u5236\u5fa1\u3057\u3066\u3044\u308b\u6a5f\u69cb\u3092\u660e\u3089\u304b\u306b\u3057\u3066\u3001\u30ec\u30bb\u30d7\u30bf\u30fc\u6a5f\u80fd\u963b\u5bb3\u5264\u306e\u958b\u767a\u306b\u7d50\u3073\u3064\u3051\u308b\u65b9\u5411\u3067\u7814\u7a76\u3092\u9032\u3081\u3066\u3044\u308b\u3002<br \/>\n\u307e\u305f\u3001\u5148\u5929\u6027\u51dd\u56fa\u7570\u5e38\u75c7\u306e\u907a\u4f1d\u5b50\u89e3\u6790\u3092\u9032\u3081\u308b\u3068\u5171\u306b\u3001\u5148\u5929\u6027\u8840\u5c0f\u677f\u6e1b\u5c11\u75c7\u306e\u907a\u4f1d\u5b50\u89e3\u6790\u3082\u884c\u3063\u3066\u3044\u308b\u3002<br \/>\n\u305d\u306e\u4e2d\u3067\u3001\u79c1\u9054\u306f\u82e5\u5e74\u6027\u52d5\u9759\u8108\u8840\u6813\u75c7\u3068\u8840\u5c0f\u677f\u6e1b\u5c11\u304c\u4e26\u884c\u3057\u3066\u591a\u767a\u3057\u3066\u3044\u308b\u5bb6\u7cfb\u306e\u907a\u4f1d\u5b50\u89e3\u6790\u304b\u3089\u3001\u307e\u3060\u6a5f\u80fd\u304c\u77e5\u3089\u308c\u3066\u3044\u306a\u3044G\u86cb\u767d\u5171\u5f79\u578b\u53d7\u5bb9\u4f53\u907a\u4f1d\u5b50\u306e\u5909\u7570\u3092\u540c\u5b9a\u3057\u305f\u3002\u672c\u5bb6\u7cfb\u3067\u306e\u539f\u56e0\u907a\u4f1d\u5b50\u306f\u8840\u5c0f\u677f\u6e1b\u5c11\u3068\u8840\u6813\u6027\u7d20\u56e0\u306e\u4e21\u75c5\u614b\u306b\u95a2\u9023\u3057\u3066\u3044\u308b\u3068\u8003\u3048\u3001\u60a3\u8005\u8840\u5c0f\u677f\u306e\u89e3\u6790\u3092\u9032\u3081\u3066\u304a\u308a\u3001\u79c1\u9054\u304c\u4f5c\u6210\u3057\u305f\u30e2\u30ce\u30af\u30ed\u30fc\u30ca\u30eb\u6297\u4f53\u3092\u7528\u3044\u3066\u8840\u5c0f\u677f\u6a5f\u80fd\u3068\u7d30\u80de\u5185\u30b7\u30b0\u30ca\u30eb\u4f1d\u9054\u3068\u306e\u95a2\u9023\u3092\u89e3\u6790\u3057\u3066\u3044\u308b\u3002\u672c\u5bb6\u7cfb\u3067\u306e\u75c5\u614b\u304c\u660e\u3089\u304b\u306b\u306a\u308c\u3070\u3001\u305d\u306e\u77e5\u898b\u306f\u8840\u5c0f\u677f\u6e1b\u5c11\u75c7\u304a\u3088\u3073\u8840\u6813\u75c7\u306e\u65b0\u305f\u306a\u6cbb\u7642\u85ac\u306e\u958b\u767a\u6226\u7565\u306e\u57fa\u76e4\u306b\u306a\u308b\u3068\u601d\u308f\u308c\u308b\u3002<br \/>\n<supan>\uff08\u5c71\u4e4b\u5185\u7d14\uff09<\/supan>\n<\/p>\n<\/div>\n<\/div>\n<p class=\"pagetop\"><a href=\"#\">PAGE TOP<\/a><\/p>\n<div class=\"research-detail4\">\n<h3>\u60aa\u6027\u30ea\u30f3\u30d1\u816b\u3084\u9aa8\u8edf\u90e8\u8089\u816b\u306e\u9032\u5c55\u3068\u4e88\u5f8c\u306b\u95a2\u308f\u308b\u56e0\u5b50\u306e\u89e3\u6790<br \/><span>Analysis of the factors related to the progression mechanism and prognosis of \u2018malignant lymphoma\u2019 and \u2018bone and soft tissue sarcoma\u2019.<\/span><\/h3>\n<div class=\"research-detail4-inner\">\n<div><img decoding=\"async\" src=\".\/wordpress\/wp-content\/uploads\/2015\/06\/img-research3.jpg\" alt=\"\" \/><\/div>\n<p>\n\u60aa\u6027\u30ea\u30f3\u30d1\u816b\u306e\u4e88\u5f8c\u4e0d\u826f\u30b0\u30eb\u30fc\u30d7\u304b\u3089\u3001\u907a\u4f1d\u5b50\u30af\u30ed\u30fc\u30cb\u30f3\u30b0\u6cd5\u306b\u3088\u308a\u816b\u760d\u95a2\u9023\u907a\u4f1d\u5b50\u3092\u540c\u5b9a\uff08\u3073\u307e\u3093\u6027\u5927\u7d30\u80de\u578bB\u7d30\u80de\u6027\u30ea\u30f3\u30d1\u816b\u304b\u3089Aurora-A\u3001\u6ffe\u80de\u6027\u30ea\u30f3\u30d1\u816b\u304b\u3089AID\u3001IRF-8\u3001CD20 splicing variants\u7b49\uff09\u3057\u3001\u3053\u308c\u3089\u907a\u4f1d\u5b50\u306e\u89e3\u6790\u3092\u8a66\u307f\u3066\u3044\u308b\uff08\u57fa\u790e\u7814\u7a76\uff09\u3002<br \/>\u5f53\u79d1\u3067\u7279\u306b\u7d4c\u9a13\u306e\u8c4a\u5bcc\u306aprimary ocular adnexal (POA) MALT\u30ea\u30f3\u30d1\u816b\u306e\u3001\u81e8\u5e8a\u30c7\u30fc\u30bf\u4e26\u3073\u306b\u767a\u75c7\u75c5\u56e0\u306e\u691c\u8a0e\u3092\u304a\u3053\u306a\u3063\u3066\u3044\u308b\u3002\u3053\u306ePOA- MALT\u30ea\u30f3\u30d1\u816b\u306e\u75c5\u56e0\u306f\u4e0d\u660e\u3068\u3055\u308c\u3066\u304a\u308a\u3001\u60a3\u8005\u691c\u4f53\u304b\u3089genomic DNA\u3092\u7528\u3044\u3066\u305d\u306e\u540c\u5b9a\u3092\u8a66\u307f\u3066\u3044\u308b\uff08\u57fa\u790e\u301c\u81e8\u5e8a\u7814\u7a76\uff09\u3002 <br \/>\u9aa8\u8edf\u90e8\u8089\u816b\uff08bone and soft tissue sarcoma\uff09\u306f\u5e0c\u5c11\u304c\u3093\uff08\u4eba\u53e310\u4e07\u4eba\u5f53\u305f\u308a6\u4eba\u672a\u6e80\u306e\u816b\u760d\uff09\u306e\u4ee3\u8868\u7684\u75be\u60a3\u3067\u3001\u73fe\u5728\u96c6\u7d04\u5316\u6cbb\u7642\u304c\u5531\u3048\u3089\u308c\u3066\u3044\u308b\u3002\u3057\u304b\u3057\u306a\u304c\u3089\u3001\u81e8\u5e8a\u7684\u306a\u691c\u8a0e\u304b\u3089\u3001\u96c6\u7d04\u5316\u6cbb\u7642\u304c\u5fc5\u305a\u3057\u3082\u60a3\u8005\u3055\u3093\u306e\u4e88\u5f8c\u306b\u826f\u3044\u5f71\u97ff\u3092\u4e0e\u3048\u3066\u3044\u308b\u3068\u306f\u9650\u3089\u305a\u3001\u5730\u57df\u3067\u6cbb\u7642\u306b\u643a\u308f\u308b\u816b\u760d\uff08\u5185\u79d1\uff09\u533b\u306e\u5b58\u5728\u304c\u5fc5\u8981\u3067\u3042\u308b\u4e8b\u3092\u5831\u544a\u3057\u305f\uff08\u81e8\u5e8a\u7814\u7a76\uff09\u3002<br \/>\n<supan>\uff08\u85ac\u5e2b\u795e\u82b3\u6d0b\uff09<\/supan><br \/>\n<\/p>\n<\/div>\n<\/div>\n<div class=\"research-detail5\">\n<h3>\u767d\u8840\u75c5\u30fb\u9aa8\u9ac4\u5897\u6b96\u6027\u816b\u760d\u306b\u304a\u3051\u308b\u907a\u4f1d\u5b50\u7570\u5e38<br \/><span>The gene abnormalities in leukemia, myeloproliferative neoplasm<\/span><\/h3>\n<p>\u767d\u8840\u75c5\u3084\u9aa8\u9ac4\u5897\u6b96\u6027\u816b\u760d\u306e\u767a\u75c7\u30fb\u9032\u5c55\u6a5f\u69cb\u3092\u5206\u5b50\u30ec\u30d9\u30eb\u3067\u691c\u8a0e\u3057\u3066\u3044\u308b\u3002\u3053\u308c\u307e\u3067\u306b\u3001\u591a\u304f\u306e\u767d\u8840\u75c5\u7d30\u80de\u682a\u3092\u6a39\u7acb\u3057\u3001\u305d\u308c\u3089\u3092\u7528\u3044\u3066\u9020\u8840\u7d30\u80de\u306e\u5897\u6b96\u30fb\u5206\u5316\u306b\u3064\u304d\u3001\u30b5\u30a4\u30c8\u30ab\u30a4\u30f3\u306e\u30b7\u30b0\u30ca\u30eb\u4f1d\u9054\u6a5f\u69cb\u306b\u7126\u70b9\u3092\u5f53\u3066\u89e3\u6790\u3057\u3066\u304d\u305f\u3002\u307e\u305f\u3001\u65b0\u305f\u306a\u878d\u5408\u907a\u4f1d\u5b50\u7570\u5e38\u3092\u540c\u5b9a\u3057\u3001\u9020\u8840\u5e79\u7d30\u80de\u306e\u5897\u6b96\u30fb\u5206\u5316\u306b\u95a2\u9023\u3042\u308b\u3068\u601d\u308f\u308c\u308b\u5206\u5b50\u3092gene silencing technology \u306e\u624b\u6cd5\u3092\u7528\u3044\u3066\u89e3\u6790\u3092\u9032\u3081\u3066\u3044\u308b\u3002<br \/>\n\u305d\u306e\u4e2d\u3067\u3082\u3001\u79c1\u9054\u306fZNF521 \u306b\u6ce8\u76ee\u3057\u3066\u89e3\u6790\u3092\u884c\u3063\u3066\u3044\u308b\u3002\u3053\u306e\u8ee2\u5199\u56e0\u5b50\u306f\u30d2\u30c8CD34\u967d\u6027\u9020\u8840\u5e79\u7d30\u80de\u3084\u591a\u304f\u306e\u6025\u6027\u9aa8\u9ac4\u6027\u767d\u8840\u75c5\u7d30\u80de\u306b\u9ad8\u767a\u73fe\u3057\u3066\u3044\u308b\u3002\u767d\u8840\u75c5\u7d30\u80de\u682a\u306eZNF521\u306e\u767a\u73fe\u3092\u6291\u5236\u3059\u308b\u3053\u3068\u306b\u3088\u3063\u3066\u3001\u591a\u5206\u5316\u80fd\u3092\u6709\u3059\u308b\u672a\u719f\u9020\u8840\u7d30\u80de\u304c\u8d64\u8840\u7403\u7cfb\u306b\u5206\u5316\u3059\u308b\u3053\u3068\u3092\u521d\u3081\u3066\u660e\u3089\u304b\u306b\u3057\u305f\u3002\u3055\u3089\u306b\u3001ZNF521\u306e\u30de\u30a6\u30b9\u30db\u30e2\u30ed\u30fc\u30b0\u3067\u3042\u308bEvi3\u907a\u4f1d\u5b50\u3092\u30ce\u30c3\u30af\u30a2\u30a6\u30c8\u3057\u305f\u30de\u30a6\u30b9\u3092\u4f5c\u88fd\u3057\u3001\u9020\u8840\u6a5f\u80fd\u306f\u3082\u3061\u308d\u3093\u3001\u305d\u306e\u751f\u4f53\u5185\u3067\u306e\u6a5f\u80fd\u3092\u7db2\u7f85\u7684\u306b\u89e3\u6790\u3057\u3066\u3044\u308b\u3002<br \/>\n\u307e\u305f\u3001\u9aa8\u9ac4\u5897\u6b96\u6027\u816b\u760d\u306e\u539f\u56e0\u907a\u4f1d\u5b50\u7570\u5e38\u3068\u3057\u3066JAK2\u5909\u7570\u3001MPL\u5909\u7570\u3001Calreticulin\u5909\u7570\u304c\u767a\u898b\u3055\u308c\u3066\u3044\u308b\u304c\u3001\u305d\u308c\u305e\u308c\u306e\u5909\u7570\u3092\u6709\u3059\u308b\u60a3\u8005\u306e\u75be\u60a3\u306e\u7279\u5fb4\u306b\u3064\u3044\u3066\u8abf\u67fb\u3059\u308b\u3068\u5171\u306b\u3001\u305d\u306e\u6a5f\u69cb\u306b\u3064\u3044\u3066\u89e3\u6790\u3092\u884c\u3063\u3066\u3044\u308b\u3002<br \/>\n<supan>\uff08\u5c71\u4e4b\u5185\u7d14\uff09<\/supan>\n<\/p>\n<div class=\"research-detail5-img01\"><img decoding=\"async\" src=\".\/wordpress\/wp-content\/uploads\/2015\/06\/img-research4.jpg\" alt=\"\" \/><\/div>\n<\/div>\n<p class=\"pagetop\"><a href=\"#\">PAGE TOP<\/a><\/p>\n<div class=\"research-detail6\">\n<h3>\u81a0\u539f\u75c5\u306e\u75c5\u614b\u89e3\u6790\u3068\u65b0\u305f\u306a\u6cbb\u7642\u6cd5\u306e\u958b\u767a<br \/><span>Development of pathology analysis and new treatment of collagen diseases<\/span><\/h3>\n<div><img decoding=\"async\" src=\".\/wordpress\/wp-content\/uploads\/2015\/06\/img-research5.jpg\" alt=\"\" \/><\/div>\n<\/p>\n<div class=\"research-detail6-inner\">\n<p class=\"detail7-inner-top-majin\">\u81a0\u539f\u75c5\u306f\u96e3\u6cbb\u6027\u3067\u3001\u65b0\u305f\u306a\u6cbb\u7642\u6cd5\u306e\u958b\u767a\u304c\u671b\u307e\u308c\u3066\u3044\u308b\u3002<br \/>\n\u3053\u308c\u307e\u3067\u306b\u751f\u7406\u6d3b\u6027\u7269\u8cea\u3092\u7528\u3044\u3066\u52b9\u7387\u3088\u3044\u5bdb\u5bb9\u578b\u6a39\u72b6\u7d30\u80de\u306e\u8a98\u5c0e\u6cd5\u3092\u78ba\u7acb\u3057\u305f\u3002\u3055\u3089\u306b\u3001\u3053\u308c\u3089\u3092\u7528\u3044\u3066\u6297\u539f\u7279\u7570\u7684\u5236\u5fa1\u6027T\u7d30\u80de\u8a98\u5c0e\u6cd5\u3092\u78ba\u7acb\u3057\u3001\u65b0\u305f\u306a\u7d30\u80de\u7642\u6cd5\u3092\u76ee\u6307\u3057\u3066\u7814\u7a76\u3092\u3059\u3059\u3081\u3066\u3044\u308b\u3002\u5bfe\u8c61\u75be\u60a3\u306f\u3001\u9593\u63a5\u30ea\u30a6\u30de\u30c1\u3068\u30b7\u30a7\u30fc\u30b0\u30ec\u30f3\u75c7\u5019\u7fa4\u3067\u3042\u308b\u3002<br \/>\n<supan>\uff08\u9577\u8c37\u5ddd\u5747\uff09<\/supan><br \/>\n<\/p>\n<\/div>\n<\/div>\n<p class=\"pagetop\"><a href=\"#\">PAGE TOP<\/a><\/p>\n<div class=\"research-detail7\">\n<h3>\u81a0\u539f\u75c5\u30fb\u30ea\u30a6\u30de\u30c1\u75be\u60a3\u306b\u304a\u3051\u308b\u65b0\u305f\u306a\u81ea\u5df1\u6297\u4f53<br \/><span class=\"indent\">\u304a\u3088\u3073\u6d3b\u52d5\u6027\u30d0\u30a4\u30aa\u30de\u30fc\u30ab\u30fc\u306b\u95a2\u3059\u308b\u7814\u7a76<\/span><span>Study on new autoantibodies and activity biomarkers in collagen diseases and rheumatic diseases<\/span><\/h3>\n<div class=\"research-detail7-inner\">\n<p>\u81a0\u539f\u75c5\u30fb\u30ea\u30a6\u30de\u30c1\u75be\u60a3\u306e\u8a3a\u65ad\u30fb\u6cbb\u7642\u306b\u304a\u3044\u3066\u306f\u3001\u305d\u306e\u6307\u6a19\u3068\u306a\u308b\u81ea\u5df1\u6297\u4f53\u3084\u6d3b\u52d5\u6027\u30d0\u30a4\u30aa\u30de\u30fc\u30ab\u30fc\u304c\u91cd\u8981\u3067\u3042\u308b\u3002<br \/>\u3053\u306e\u305f\u3081\u3001\u7121\u7d30\u80de\u30bf\u30f3\u30d1\u30af\u8cea\u5408\u6210\u7cfb\u3084\u7d76\u5bfe\u5b9a\u91cf\u30d7\u30ed\u30c6\u30aa\u30fc\u30e0\u89e3\u6790\u3092\u7528\u3044\u3066\u3001\u30eb\u30fc\u30d7\u30b9\u814e\u708e\u3084ANCA\u95a2\u9023\u8840\u7ba1\u708e\u306e\u65b0\u305f\u306a\u81ea\u5df1\u6297\u4f53\u3084\u30d0\u30a4\u30aa\u30de\u30fc\u30ab\u30fc\u306e\u7814\u7a76\u3092\u3059\u3059\u3081\u3066\u3044\u308b\u3002\u30eb\u30fc\u30d7\u30b9\u814e\u708e\u306b\u304a\u3044\u3066\u306f\u3001\u65b0\u305f\u306a\u81ea\u5df1\u6297\u539f\u3068\u3057\u3066RRP8\u3084TNP-1\u3092\u767a\u898b\u3057\u305f\u3002ANCA\u95a2\u9023\u8840\u7ba1\u708e\u306b\u304a\u3044\u3066\u306f\u3001\u539a\u751f\u52b4\u50cd\u7701\u96e3\u6cbb\u6027\u8840\u7ba1\u708e\u306b\u95a2\u3059\u308b\u8abf\u67fb\u7814\u7a76\u73ed\u3067\u96c6\u3081\u3089\u308c\u305f\u8840\u6e05\u3092\u7528\u3044\u3066\u3001target proteomics\u306e\u624b\u6cd5\u306b\u3088\u3063\u3066\u3001TIMP-1\u306a\u3069\u6709\u671b\u306a\u6d3b\u52d5\u6027\u30d0\u30a4\u30aa\u30de\u30fc\u30ab\u30fc\u3092\u898b\u51fa\u3057\u305f\u3002\u3053\u308c\u3089\u306e\u7814\u7a76\u6210\u679c\u306f\u3044\u305a\u308c\u3082\u56fd\u969b\u7684\u306b\u9ad8\u304f\u8a55\u4fa1\u3055\u308c\u3066\u3044\u308b\u3002\u73fe\u5728\u3001\u3053\u308c\u3089\u306e\u30de\u30fc\u30ab\u30fc\u304c\u5b9f\u81e8\u5e8a\u306b\u5f79\u7acb\u3064\u304b\u3069\u3046\u304b\u691c\u8a3c\u3057\u3066\u3044\u308b\u3002<br \/>\n<supan>\uff08\u9577\u8c37\u5ddd\u5747\uff09<\/supan><br \/>\n<\/p>\n<div><img decoding=\"async\" src=\".\/wordpress\/wp-content\/uploads\/2015\/06\/img-research6.jpg\" alt=\"\" \/><\/div>\n<\/div>\n<\/div>\n<p class=\"pagetop\"><a href=\"#\">PAGE TOP<\/a><\/p>\n<div class=\"research-detail8-01\">\n<h3>SFTS\u767a\u75c5\u30fb\u91cd\u75c7\u5316\u6a5f\u69cb\u306b\u95a2\u308f\u308b\u5bbf\u4e3b\u56e0\u5b50\u306e\u63a2\u7d22\u7684\u7814\u7a76<br \/>\nHost factors related to Pathogenesis of SFTS (HoPS study)<\/h3>\n<div class=\"research-detail8-inner\">\n<div class=\"research-detail8-img01 pc-only\"><img decoding=\"async\" src=\"\/school\/int.med1\/wordpress\/img\/pages\/img-research_bg_2.jpg\" alt=\"\" class=\"pc-only\"\/><\/div>\n<p>\u91cd\u7be4\u306a\u611f\u67d3\u75c7\u3067\u3042\u308bSFTS\u306e\u6709\u52b9\u306a\u6cbb\u7642\u6cd5\u3092\u78ba\u7acb\u3059\u308b\u305f\u3081\u306b\u306f\u3001\u305d\u306e\u767a\u75c5\u30fb\u91cd\u75c7\u5316\u6a5f\u69cb\u3092\u6b63\u3057\u304f\u7406\u89e3\u3059\u308b\u5fc5\u8981\u304c\u3042\u308b\u3002\u672c\u7814\u7a76\u3067\u306fSFTS\u3067\u898b\u3089\u308c\u308b\u7570\u578b\u30ea\u30f3\u30d1\u7403\u306b\u7126\u70b9\u3092\u5f53\u3066\u3001\u60a3\u8005\u691c\u4f53\u3092\u7528\u3044\u305f\u907a\u4f1d\u5b50\u767a\u73fe\u89e3\u6790\u3001\u6297\u4f53\u907a\u4f1d\u5b50\u914d\u5217\u30ec\u30d1\u30c8\u30a2\u89e3\u6790\u7b49\u306b\u3088\u308a\u7570\u578b\u30ea\u30f3\u30d1\u7403\u306e\u7279\u5fb4\u3092\u660e\u3089\u304b\u306b\u3057SFTS\u767a\u75c5\u30fb\u91cd\u75c7\u5316\u6a5f\u69cb\u306e\u89e3\u660e\u3092\u76ee\u6307\u3057\u3066\u304a\u308a\u3001\u5f53\u9662\u3082\u3053\u306e\u7814\u7a76\uff08\u4ee3\u8868\u6a5f\u95a2\uff1a\u56fd\u7acb\u611f\u67d3\u75c7\u7814\u7a76\u6240\uff09\u306b\u53c2\u52a0\u3057\u3066\u3044\u308b\u3002<br \/>\n<supan>\uff08\u672b\u76db\u6d69\u4e00\u90ce\uff09<\/supan><\/p>\n<div class=\"research-detail8-01\">\n<h3>\u91cd\u75c7\u71b1\u6027\u8840\u5c0f\u677f\u6e1b\u5c11\u75c7\u5019\u7fa4\uff08SFTS\uff09\u306b\u5bfe\u3059\u308b<br \/><span class=\"indent\">\u30a6\u30a4\u30eb\u30b9\u7279\u7570\u7684\u514d\u75ab\u5fdc\u7b54\u306e\u89e3\u6790\u304a\u3088\u3073\u81e8\u5e8a\u8a66\u9a13\u30fb\u6cbb\u9a13<\/span><span>Analysis of virus-specific immunological response and clinical study<\/span><span>trial for severe fever with thrombocytopenia syndrome(SFTS) <\/span><\/h3>\n<div class=\"research-detail8-inner\">\n<div class=\"research-detail8-img01 pc-only\"><img decoding=\"async\" src=\"\/school\/int.med1\/wordpress\/img\/pages\/img-research_bg_2.jpg\" alt=\"\" class=\"pc-only\"\/><\/div>\n<p>\u91cd\u75c7\u71b1\u6027\u8840\u5c0f\u677f\u6e1b\u5c11\u75c7\u5019\u7fa4\uff08SFTS\uff09\u306f2011\u5e74\u306b\u4e2d\u56fd\u3067\u521d\u3081\u3066\u5831\u544a\u3055\u308c\u305f\u65b0\u8208\u611f\u67d3\u75c7\u3067\u3042\u308b\u304c\u3001\u305d\u306e\u75c5\u614b\u306f\u4e0d\u660e\u306a\u70b9\u304c\u591a\u3044\u3002\u6211\u304c\u56fd\u3067\u30822013\u5e74\u4ee5\u964d\u60a3\u8005\u306e\u5831\u544a\u304c\u76f8\u6b21\u3044\u3067\u304a\u308a\u3001\u305d\u306e\u89e3\u660e\u304c\u5f85\u305f\u308c\u3066\u3044\u308b\u3002\u79c1\u305f\u3061\u306fSFTS\u75c7\u4f8b\u3067\u306f\u7570\u578b\u30ea\u30f3\u30d1\u7403\u306e\u51fa\u73fe\u3092\u8a8d\u3081\u3001EB\u30a6\u30a4\u30eb\u30b9\u3084\u30d2\u30c8\u30b5\u30a4\u30c8\u30e1\u30ac\u30ed\u30a6\u30a4\u30eb\u30b9\u611f\u67d3\u75c7\u306a\u3069\u3068\u7570\u306a\u308a\u3001\u3053\u306e\u7570\u578b\u30ea\u30f3\u30d1\u7403\u304c\uff22\u7d30\u80de\u3067\u3042\u308b\u3053\u3068\u3092\u660e\u3089\u304b\u306b\u3057\u305f\u3002\u3064\u307e\u308a\u3001\u901a\u5e38\u306e\u30a6\u30a4\u30eb\u30b9\u611f\u67d3\u75c7\u3068\u306f\u514d\u75ab\u5fdc\u7b54\u304c\u7570\u306a\u308b\u3053\u3068\u304c\u793a\u5506\u3055\u308c\u308b\u305f\u3081\u3001\u73fe\u5728\u75c7\u4f8b\u3092\u84c4\u7a4d\u3057\u89e3\u6790\u3092\u884c\u3063\u3066\u3044\u308b\u3002\n<\/p>\n<p>\u4e00\u65b9\u3001\u672c\u75be\u60a3\u306f\u81f4\u6b7b\u7387\u304c10\uff5e30%\u3068\u6975\u3081\u3066\u9ad8\u304f\u3001\u6709\u52b9\u306a\u6cbb\u7642\u6cd5\u304c\u78ba\u7acb\u3055\u308c\u3066\u3044\u306a\u3044\u305f\u3081\u3001\u6cbb\u7642\u6cd5\u306e\u78ba\u7acb\u3082\u6975\u3081\u3066\u91cd\u8981\u306a\u8ab2\u984c\u3067\u3042\u308b\u3002\u30d5\u30a1\u30d3\u30d4\u30e9\u30d3\u30eb\u306f\u65b0\u8208\u578b\u30a4\u30f3\u30d5\u30eb\u30a8\u30f3\u30b6\u304c\u767a\u751f\u3057\u3001\u672c\u5264\u3092\u5f53\u8a72\u30a4\u30f3\u30d5\u30eb\u30a8\u30f3\u30b6\u30a6\u30a4\u30eb\u30b9\u3078\u4f7f\u7528\u3059\u308b\u3068\u56fd\u304c\u5224\u65ad\u3057\u305f\u5834\u5408\u306e\u307f\u3001\u60a3\u8005\u3078\u306e\u6295\u4e0e\u304c\u691c\u8a0e\u3055\u308c\u308b\u533b\u85ac\u54c1\u3067\u3042\u308b\u304c\u3001SFTS\u30a6\u30a4\u30eb\u30b9\u3092\u611f\u67d3\u3055\u305b\u305f\u52d5\u7269\u3092\u5bfe\u8c61\u3068\u3057\u305f\u5b9f\u9a13\u7d50\u679c\u304b\u3089\u3001\u30d5\u30a1\u30d3\u30d4\u30e9\u30d3\u30eb\u304cSFTS\u306b\u3082\u6709\u52b9\u3067\u3042\u308b\u3053\u3068\u304c\u793a\u3055\u308c\u305f\u3002\u3053\u306e\u7d50\u679c\u3092\u53d7\u3051\u3001\u5f53\u9662\u3067\u306f\u3053\u306e\u85ac\u5264\u3092\u7528\u3044\u305f\u533b\u5e2b\u4e3b\u5c0e\u578b\u306e\u81e8\u5e8a\u8a66\u9a13\uff082016\u5e744\u6708\uff5e2018\u5e747\u6708\u3001\u591a\u65bd\u8a2d\u5171\u540c\u30fb\u30aa\u30fc\u30d7\u30f3\u30e9\u30d9\u30eb\u30fb\u975e\u5bfe\u7167\u8a66\u9a13\uff09\u304c\u884c\u308f\u308c\u305f\u3002\u307e\u305f\u4ee5\u5f8c\u306e\u4f01\u696d\u6cbb\u9a13\uff082018\u5e74\uff5e\u3001\u591a\u65bd\u8a2d\u5171\u540c\u30fb\u30aa\u30fc\u30d7\u30f3\u30e9\u30d9\u30eb\u30fb\u65e2\u5b58\u5bfe\u7167\u8a66\u9a13\uff09\u306b\u3082\u53c2\u52a0\u3057\u3066\u3044\u308b\u3002\u3053\u308c\u3089\u306e\u8a66\u9a13\u306f\u65e2\u306b\u7d42\u4e86\u3057\u3001\u826f\u597d\u306a\u7d50\u679c\u304c\u5f97\u3089\u308c\u3066\u304a\u308a\u3001\u30d5\u30a1\u30d3\u30d4\u30e9\u30d3\u30eb\u306fSFTS\u60a3\u8005\u306b\u5bfe\u3059\u308b\u6297\u30a6\u30a4\u30eb\u30b9\u85ac\u3068\u3057\u30662023\u5e745\u6708\u306b\u539a\u751f\u52b4\u50cd\u7701\u85ac\u4e8b\u30fb\u98df\u54c1\u885b\u751f\u5be9\u8b70\u4f1a\u306e\u90e8\u4f1a\u3067\u3001\u85ac\u4e8b\u627f\u8a8d\u7533\u8acb\u306e\u512a\u5148\u5be9\u67fb\u306a\u3069\u512a\u9047\u63aa\u7f6e\u3092\u53d7\u3051\u3089\u308c\u308b\u300c\u5e0c\u5c11\u75be\u75c5\u7528\u533b\u85ac\u54c1\uff08\u30aa\u30fc\u30d5\u30a1\u30f3\u30c9\u30e9\u30c3\u30b0\uff09\u300d\u306e\u6307\u5b9a\u304c\u8a8d\u3081\u3089\u308c\u3001\u81e8\u5e8a\u3067\u306e\u4f7f\u7528\u304c\u671f\u5f85\u3055\u308c\u3066\u3044\u308b\u3002<br \/>\n<supan>\uff08\u672b\u76db\u6d69\u4e00\u90ce\uff09<\/supan>\n<\/p>\n<div class=\"research-detail8-img01 sp-only\"><img decoding=\"async\" src=\"\/school\/int.med1\/wordpress\/img\/pages\/img-research_bg_2_sp.jpg\" alt=\"\" \/><\/div>\n<\/div>\n<\/div>\n<p class=\"pagetop\"><a href=\"#\">PAGE TOP<\/a><\/p>\n<h3>\u30de\u30c0\u30cb\u523a\u54ac\u5f8c\u306e\u767a\u71b1\u75be\u60a3\u30ec\u30b8\u30b9\u30c8\u30ea\u306e\u69cb\u7bc9<br \/>\nEstablishment of a fever disease registry after tick bites.<\/h3>\n<p>\u65e5\u672c\u5168\u56fd\u306b\u304a\u3051\u308b\u3001\u30de\u30c0\u30cb\u5a92\u4ecb\u611f\u67d3\u75c7\u304c\u7591\u308f\u308c\u308b\u304c\u539f\u56e0\u4e0d\u660e\u306e\u767a\u71b1\u75be\u60a3\u306e\u75c7\u4f8b\u306e\u30ec\u30b8\u30b9\u30c8\u30ea\u3092\u69cb\u7bc9\u3057\u3001\u75c7\u4f8b\u60c5\u5831\u3068\u5171\u306b\u8840\u6db2\u306a\u3069\u306e\u691c\u4f53\u3092\u53ce\u96c6\u3057\u3001\u539f\u56e0\u5fae\u751f\u7269\u306e\u540c\u5b9a\u3092\u8a66\u307f\u3089\u308c\u3066\u304a\u308a\u3001\u5f53\u9662\u3082\u3053\u306e\u7814\u7a76\uff08\u4ee3\u8868\u6a5f\u95a2\uff1a\u56fd\u7acb\u611f\u67d3\u75c7\u7814\u7a76\u6240\uff09\u306b\u53c2\u52a0\u3057\u3066\u3044\u308b\u3002<br \/>\n<supan>\uff08\u672b\u76db\u6d69\u4e00\u90ce\uff09<\/supan><\/p>\n<h3>COVID-19\u306e\u6d41\u884c\u72b6\u6cc1\u3084mRNA\u30ef\u30af\u30c1\u30f3\u306b\u5bfe\u3059\u308b\u6297\u4f53\u7523\u751f\u306b\u95a2\u3059\u308b\u89b3\u5bdf\u7814\u7a76<br \/>\nObservational studies on the prevalence of COVID-19 and antibody production to mRNA vaccines.<\/h3>\n<p>2019\u5e74\u306b\u4e2d\u56fd\u3067\u521d\u3081\u3066\u5831\u544a\u3055\u308c\u305f\u65b0\u578b\u30b3\u30ed\u30ca\u30a6\u30a4\u30eb\u30b9\u611f\u67d3\u75c7\uff08COVID-19\uff09\u306f\u4e16\u754c\u7684\u30d1\u30f3\u30c7\u30df\u30c3\u30af\u3068\u306a\u308a\u3001\u73fe\u5728\u3082\u6700\u3082\u6ce8\u76ee\u3055\u308c\u3066\u3044\u308b\u65b0\u8208\u611f\u67d3\u75c7\u306e\uff11\u3064\u3067\u3042\u308b\u3002\u305d\u306e\u6d41\u884c\u72b6\u6cc1\u306f\u56fd\u3084\u5730\u57df\u306b\u3088\u308a\u7570\u306a\u3063\u3066\u304a\u308a\u3001\u5b9a\u671f\u7684\u306a\u30b5\u30fc\u30d9\u30a4\u30e9\u30f3\u30b9\u304c\u5fc5\u8981\u3067\u3042\u308b\u3002\u3053\u308c\u306b\u52a0\u3048\u3001\u65b0\u898f\u306emRNA\u30ef\u30af\u30c1\u30f3\u306e\u9577\u671f\u7684\u306a\u6709\u52b9\u6027\u3084\u63a5\u7a2e\u56de\u6570\u306b\u3064\u3044\u3066\u306e\u691c\u8a3c\u3082\u5341\u5206\u3068\u306f\u8a00\u3048\u306a\u3044\u3002\u5f53\u79d1\u3067\u306f\u5f53\u9662\u306e\u8077\u54e1\u3084\u5916\u6765\u60a3\u8005\uff08\u514d\u75ab\u4e0d\u5168\u60a3\u8005\u542b\u3080\uff09\u3092\u901a\u3058\u3066\u9577\u671f\u7684\u306a\u89b3\u5bdf\u7814\u7a76\u3092\u5b9f\u65bd\u3057\u3066\u3044\u308b\u3002<br \/>\n<supan>\uff08\u672b\u76db\u6d69\u4e00\u90ce\uff09<\/supan><\/p>\n<div class=\"research-detail8-02\">\n<h3>HIV\u611f\u67d3\u8005\u30fb\u30a8\u30a4\u30ba\u60a3\u8005\u306b\u5bfe\u3059\u308b<br \/>\n<span class=\"indent\">\u4e2d\u6838\u62e0\u70b9\u75c5\u9662\u306e\u6a5f\u80fd\u8a55\u4fa1\u3068\u533b\u7642\u4f53\u5236\u306e\u6574\u5099<\/span><span>Functional assessment and medical system in AIDS Core Hospital for HIV\/AIDS patients <\/span><\/h3>\n<div class=\"research-detail8-inner\">\n<p>\u56db\u56fd\u5730\u533a\u306f\u9ad8\u9f62\u5316\u7387\u304c29%\u524d\u5f8c\u306e\u5730\u65b9\u3067\u3042\u308a\u3001\u90fd\u5e02\u306b\u6bd4\u3079\u9ad8\u9f62\u8005\u306eHIV\/AIDS\u60a3\u8005\u304c\u591a\u3044\u3053\u3068\u306b\u52a0\u3048\u3001HIV\u6cbb\u7642\u85ac\u306e\u5287\u7684\u306a\u9032\u6b69\u306b\u4f34\u3044\u3001\u60a3\u8005\u306e\u9ad8\u9f62\u5316\u304c\u66f4\u306b\u9032\u3080\u3053\u3068\u304c\u4e88\u60f3\u3055\u308c\u3066\u3044\u308b\u3002\u3053\u308c\u307e\u3067\u3001\u611b\u5a9b\u770c\u4e0b\u3067\u306f\u30a8\u30a4\u30ba\u4e2d\u6838\u62e0\u70b9\u75c5\u9662\u306b\u60a3\u8005\u304c\u96c6\u7d04\u3055\u308c\u3066\u304d\u305f\u304c\u3001HIV\u611f\u67d3\u75c7\u304c\u6162\u6027\u75be\u60a3\u3078\u3068\u5909\u5316\u3057\u305f\u4eca\u3001\u5730\u57df\u306e\u75c5\u9662\u3084\u4ecb\u8b77\u7642\u990a\u65bd\u8a2d\u306b\u81f3\u308b\u307e\u3067\u5e45\u5e83\u3044\u8a3a\u7642\u4f53\u5236\u306e\u69cb\u7bc9\u304c\u5fc5\u8981\u3068\u306a\u3063\u3066\u3044\u308b\u3002\u4e00\u65b9\u3001\u75be\u60a3\u306b\u5bfe\u3059\u308b\u504f\u898b\u3001\u4e0d\u5b89\u3001\u7d4c\u9a13\u4e0d\u8db3\u304b\u3089\u4ed6\u65bd\u8a2d\u3078\u306e\u7d39\u4ecb\u3084\u53d7\u3051\u5165\u308c\u306b\u96e3\u6e0b\u3059\u308b\u3053\u3068\u3082\u5c11\u306a\u304f\u306a\u304f\u3001\u5730\u57df\u3078\u306e\u5553\u767a\u6d3b\u52d5\u3082\u91cd\u8981\u3067\u3042\u308b\u3002\u3053\u306e\u3088\u3046\u306a\u80cc\u666f\u304b\u3089\u3001<br \/>\n\u2460\u62e0\u70b9\u75c5\u9662\u3092\u4e2d\u5fc3\u3068\u3057\u305f\u6559\u80b2\u8b1b\u6f14\u3001\u610f\u898b\u4ea4\u63db\u3001\u7814\u4fee\u6559\u6750\u306e\u4f5c\u88fd<br \/>\n\u2461\u611b\u5a9b\u770c\u306e\u9ad8\u9f62\u8005\u65bd\u8a2d\u306b\u304a\u3051\u308bHIV\u611f\u67d3\u75c7\u7b49\u306b\u95a2\u3059\u308b\u7814\u4fee\u4f1a\u306e\u958b\u50ac\u304a\u3088\u3073\u5b9f\u614b\u8abf\u67fb<br \/>\n\u2462\u798f\u7949\u7642\u990a\u65bd\u8a2d\u3078\u306e\u51fa\u5f35\u7814\u4fee\u3001\u610f\u898b\u4ea4\u63db<br \/>\n\u2463\u5730\u57df\u3067\u5b9f\u8df5\u7684\u306a\u30dd\u30b1\u30c3\u30c8\u7248\u5c0f\u518a\u5b50\u306e\u4f5c\u88fd<br \/>\n\u2464\u5728\u5b85\u4ecb\u8b77\u8077\u54e1\u3078\u306e\u5b9f\u5730\u7814\u4fee<br \/>\n\u3092\u884c\u3044\u3001\u611b\u5a9b\u770c\u4e0b\u306eHIV\/AIDS\u8a3a\u7642\u4f53\u5236\u306e\u5145\u5b9f\u306b\u52aa\u3081\u3001\u66f4\u306b\u306f\u540c\u3058\u554f\u984c\u3092\u62b1\u3048\u3066\u3044\u308b\u56db\u56fd\u306e\u4ed6\u770c\u306b\u3082\u3053\u306e\u7814\u7a76\u53c2\u52a0\u3092\u4fc3\u3057\u3001\u6d3b\u52d5\u7bc4\u56f2\u306e\u62e1\u5927\u3092\u691c\u8a0e\u3057\u3066\u3044\u308b\u3002<br \/>\n<supan>\uff08\u672b\u76db\u6d69\u4e00\u90ce\uff09<\/supan>\n<\/p>\n<div class=\"research-detail8-img02\"><img decoding=\"async\" src=\"\/school\/int.med1\/wordpress\/img\/pages\/img-research8.jpg\" alt=\"\" \/>\n<\/div>\n<\/div>\n<\/div>\n<p class=\"pagetop\"><a href=\"#\">PAGE TOP<\/a><\/p>\n<\/div>\n<\/div>\n","protected":false},"excerpt":{"rendered":"<p>\u7814\u7a76\u9762\u3067\u306f\u3001\u8840\u6db2\u3001\u611f\u67d3\u75c7\u3001\u81ea\u5df1\u514d\u75ab\u75be\u60a3\u306a\u3069\u3092\u4e3b\u306a\u7814\u7a76\u5bfe\u8c61\u3068\u3057\u3066\u304a\u308a\u3001\u5206\u5b50\u30fb\u7d30\u80de\u751f\u7269\u5b66\u3001\u514d\u75ab\u5b66\u3001\u907a\u4f1d\u5b66\u3001\u751f\u5316\u5b66\u7684\u306a\u5074\u9762\u304b\u3089\u691c\u8a0e\u3092\u52a0\u3048\u3066\u3044\u307e\u3059\u3002 \u81e8\u5e8a\u306e\u5834\u3067\u906d\u9047\u3057\u305f\u554f\u984c\u70b9\u3084\u7591\u554f\u3092\u30c6\u30fc\u30de\u306b\u3057\u305f\u7814\u7a76\u3092\u5c55\u958b\u3057\u3066\u304a\u308a\u3001\u7814\u7a76\u6210\u679c\u3092\u81e8\u5e8a &hellip; <a href=\"https:\/\/www.m.ehime-u.ac.jp\/school\/int.med1\/?page_id=2097\" class=\"more-link\">\u7d9a\u304d\u3092\u8aad\u3080 <span class=\"screen-reader-text\">\u7814\u7a76\u5185\u5bb9<\/span> <span 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