{"id":1558,"date":"2016-06-01T10:50:38","date_gmt":"2016-06-01T01:50:38","guid":{"rendered":"http:\/\/www.m.ehime-u.ac.jp\/school\/int.med1\/?p=1558"},"modified":"2016-12-05T17:42:46","modified_gmt":"2016-12-05T08:42:46","slug":"%e7%a0%94%e7%a9%b6%e3%81%ab%e3%81%a4%e3%81%84%e3%81%a6%e3%80%902016%e5%b9%b4%e3%80%91","status":"publish","type":"post","link":"https:\/\/www.m.ehime-u.ac.jp\/school\/int.med1\/?p=1558","title":{"rendered":"\u7814\u7a76\u306b\u3064\u3044\u3066\u30102016\u5e74\u3011"},"content":{"rendered":"<h3>\u82f1\u6587\u539f\u8457\u8ad6\u6587\u3000Original papers<\/h3>\n<p>\u767a\u520a\u6e08\u306e\u3082\u306e\u306fabstract\u307e\u305f\u306f\u672c\u6587\u306b\u30ea\u30f3\u30af\u3057\u3066\u3042\u308a\u307e\u3059\u3002<\/p>\n<p>Published papers are linked to PubMed<\/p>\n<p><!--more--><\/p>\n<p><!--\u672c\u6587\u6587\u7bc0\u958b\u59cb\u3000\u3000\u3053\u3053\u304b\u3089\u4e00\u3064\u306e\u6587\u7ae0\u3068\u3057\u3066\u8907\u88fd\u3057\u3066\u4f7f\u7528\u3057\u3066\u304f\u3060\u3055\u3044\u3002--><br \/>\n<a href=\"\u3053\u306e\u6587\u7ae0\u3092\u30ea\u30f3\u30af\u5148\u306eURL\u3078\u5909\u66f4\u3057\u3066\u304f\u3060\u3055\u3044\"><!--\u3053\u3053\u304b\u3089\u306e\u6587\u7ae0\u3078\u30ea\u30f3\u30af\u304c\u5f35\u3089\u308c\u307e\u3059\u3002--><a href=\"http:\/\/www.ncbi.nlm.nih.gov\/pubmed\/26524263\">Fuji S, Fujiwara H, Nakano N, Wake A, Inoue Y, Fukuda T, Hidaka M, Moriuchi Y, Miyamoto T, Uike N, Taguchi J, Eto T, Tomoyose T, Kondo T, Yamanoha A, Ichinohe T, Atsuta Y, Utsunomiya A; ATL Working Group of the Japan Society for Hematopoietic Cell Transplantation.<\/a><\/a><!--\u3053\u3053\u307e\u3067\u306e\u6587\u7ae0\u3078\u30ea\u30f3\u30af\u304c\u5f35\u3089\u308c\u307e\u3059\u3002--><\/a><br \/>\nEarly application of related SCT might improve clinical outcome in adult T-cell leukemia\/lymphoma.<br \/>\nBone Marrow Transplant. 2016 Feb;51(2):205-11.<\/p>\n<hr \/>\n<p><!--\u533a\u5207\u308a\u7dda\u3092\u8868\u793a\u3059\u308bHTML\u30bf\u30b0\u3067\u3059--><br \/>\n<!--\u672c\u6587\u6587\u7bc0\u7d42\u4e86\u3000\u3000\u3053\u3053\u307e\u3067\u3092\u4e00\u3064\u306e\u6587\u7ae0\u3068\u3057\u3066\u8907\u88fd\u3057\u3066\u4f7f\u7528\u3057\u3066\u304f\u3060\u3055\u3044\u3002--><\/p>\n<p><!--\u672c\u6587\u6587\u7bc0\u958b\u59cb\u3000\u3000\u3053\u3053\u304b\u3089\u4e00\u3064\u306e\u6587\u7ae0\u3068\u3057\u3066\u8907\u88fd\u3057\u3066\u4f7f\u7528\u3057\u3066\u304f\u3060\u3055\u3044\u3002--><br \/>\n<a href=\"\u3053\u306e\u6587\u7ae0\u3092\u30ea\u30f3\u30af\u5148\u306eURL\u3078\u5909\u66f4\u3057\u3066\u304f\u3060\u3055\u3044\"><!--\u3053\u3053\u304b\u3089\u306e\u6587\u7ae0\u3078\u30ea\u30f3\u30af\u304c\u5f35\u3089\u308c\u307e\u3059\u3002--><a href=\"http:\/\/www.ncbi.nlm.nih.gov\/pubmed\/26702062\">Najima Y, Tomizawa-Murasawa M, Saito Y, Watanabe T, Ono R, Ochi T, Suzuki N, Fujiwara H, Ohara O, Shultz LD, Yasukawa M, Ishikawa F.<\/a><\/a><\/a><!--\u3053\u3053\u307e\u3067\u306e\u6587\u7ae0\u3078\u30ea\u30f3\u30af\u304c\u5f35\u3089\u308c\u307e\u3059\u3002--><\/a><br \/>\nInduction of WT1-specific human CD8+ T cells from human HSCs in HLA class I Tg NOD\/SCID\/IL2rgKO mice.<br \/>\nBlood. 2016 Feb 11;127(6):722-34.<\/p>\n<hr \/>\n<p><!--\u533a\u5207\u308a\u7dda\u3092\u8868\u793a\u3059\u308bHTML\u30bf\u30b0\u3067\u3059--><br \/>\n<!--\u672c\u6587\u6587\u7bc0\u7d42\u4e86\u3000\u3000\u3053\u3053\u307e\u3067\u3092\u4e00\u3064\u306e\u6587\u7ae0\u3068\u3057\u3066\u8907\u88fd\u3057\u3066\u4f7f\u7528\u3057\u3066\u304f\u3060\u3055\u3044\u3002--><\/p>\n<p><!--\u672c\u6587\u6587\u7bc0\u958b\u59cb\u3000\u3000\u3053\u3053\u304b\u3089\u4e00\u3064\u306e\u6587\u7ae0\u3068\u3057\u3066\u8907\u88fd\u3057\u3066\u4f7f\u7528\u3057\u3066\u304f\u3060\u3055\u3044\u3002--><br \/>\n<a href=\"\u3053\u306e\u6587\u7ae0\u3092\u30ea\u30f3\u30af\u5148\u306eURL\u3078\u5909\u66f4\u3057\u3066\u304f\u3060\u3055\u3044\"><!--\u3053\u3053\u304b\u3089\u306e\u6587\u7ae0\u3078\u30ea\u30f3\u30af\u304c\u5f35\u3089\u308c\u307e\u3059\u3002--><a href=\"http:\/\/www.ncbi.nlm.nih.gov\/pubmed\/?term=Mori+S%2C+Yamanouchi+J%2C+Okamoto+K%2C+Hato+T%2C+Yasukawa+M.\">Mori S, Yamanouchi J, Okamoto K, Hato T, Yasukawa M.<\/a><\/a><\/a><\/a><\/a><\/a><\/a><!--\u3053\u3053\u307e\u3067\u306e\u6587\u7ae0\u3078\u30ea\u30f3\u30af\u304c\u5f35\u3089\u308c\u307e\u3059\u3002--><\/a><br \/>\nA novel frameshift mutation leading to inherited type I antithrombin deficiency.<br \/>\nBlood Coagul Fibrinolysis. 2016 Mar 11. <\/p>\n<hr \/>\n<p><!--\u533a\u5207\u308a\u7dda\u3092\u8868\u793a\u3059\u308bHTML\u30bf\u30b0\u3067\u3059--><br \/>\n<!--\u672c\u6587\u6587\u7bc0\u7d42\u4e86\u3000\u3000\u3053\u3053\u307e\u3067\u3092\u4e00\u3064\u306e\u6587\u7ae0\u3068\u3057\u3066\u8907\u88fd\u3057\u3066\u4f7f\u7528\u3057\u3066\u304f\u3060\u3055\u3044\u3002--><\/p>\n<p><!--\u672c\u6587\u6587\u7bc0\u958b\u59cb\u3000\u3000\u3053\u3053\u304b\u3089\u4e00\u3064\u306e\u6587\u7ae0\u3068\u3057\u3066\u8907\u88fd\u3057\u3066\u4f7f\u7528\u3057\u3066\u304f\u3060\u3055\u3044\u3002--><br \/>\n<a href=\"\u3053\u306e\u6587\u7ae0\u3092\u30ea\u30f3\u30af\u5148\u306eURL\u3078\u5909\u66f4\u3057\u3066\u304f\u3060\u3055\u3044\"><!--\u3053\u3053\u304b\u3089\u306e\u6587\u7ae0\u3078\u30ea\u30f3\u30af\u304c\u5f35\u3089\u308c\u307e\u3059\u3002--><a href=\"http:\/\/www.ncbi.nlm.nih.gov\/pubmed\/?term=Nakatsugawa+M%2C+Rahman+MA%2C+Yamashita+Y%2C+Ochi+T%2C+Wnuk+P%2C+Tanaka+S%2C+Chamoto+K%2C+Kagoya+Y%2C+Saso+K%2C+Guo+T%2C+Anczurowski+M%2C+Butler+MO%2C+Hirano+N.\">Nakatsugawa M, Rahman MA, Yamashita Y, Ochi T, Wnuk P, Tanaka S, Chamoto K, Kagoya Y, Saso K, Guo T, Anczurowski M, Butler MO, Hirano N.<\/a><\/a><\/a><\/a><\/a><\/a><\/a><!--\u3053\u3053\u307e\u3067\u306e\u6587\u7ae0\u3078\u30ea\u30f3\u30af\u304c\u5f35\u3089\u308c\u307e\u3059\u3002--><\/a><br \/>\nCD4(+) and CD8(+) TCR\u03b2 repertoires possess different potentials to generate extraordinarily high-avidity T cells.<br \/>\nSci Rep. 2016 Mar 31;6:23821.<\/p>\n<hr \/>\n<p><!--\u533a\u5207\u308a\u7dda\u3092\u8868\u793a\u3059\u308bHTML\u30bf\u30b0\u3067\u3059--><br \/>\n<!--\u672c\u6587\u6587\u7bc0\u7d42\u4e86\u3000\u3000\u3053\u3053\u307e\u3067\u3092\u4e00\u3064\u306e\u6587\u7ae0\u3068\u3057\u3066\u8907\u88fd\u3057\u3066\u4f7f\u7528\u3057\u3066\u304f\u3060\u3055\u3044\u3002--><\/p>\n<p><!--\u672c\u6587\u6587\u7bc0\u958b\u59cb\u3000\u3000\u3053\u3053\u304b\u3089\u4e00\u3064\u306e\u6587\u7ae0\u3068\u3057\u3066\u8907\u88fd\u3057\u3066\u4f7f\u7528\u3057\u3066\u304f\u3060\u3055\u3044\u3002--><br \/>\n<a href=\"\u3053\u306e\u6587\u7ae0\u3092\u30ea\u30f3\u30af\u5148\u306eURL\u3078\u5909\u66f4\u3057\u3066\u304f\u3060\u3055\u3044\"><!--\u3053\u3053\u304b\u3089\u306e\u6587\u7ae0\u3078\u30ea\u30f3\u30af\u304c\u5f35\u3089\u308c\u307e\u3059\u3002--><a href=\"http:\/\/www.ncbi.nlm.nih.gov\/pubmed\/26749286\">Suzuki J, Maruyama S, Tamauchi H, Kuwahara M, Horiuchi M, Mizuki M, Ochi M, Sawasaki T, Zhu J, Yasukawa M, Yamashita M.<\/a><\/a><\/a><\/a><!--\u3053\u3053\u307e\u3067\u306e\u6587\u7ae0\u3078\u30ea\u30f3\u30af\u304c\u5f35\u3089\u308c\u307e\u3059\u3002--><\/a><br \/>\nGfi1, a transcriptional repressor, inhibits the induction of the T helper type 1 programme in activated CD4 T cells.<br \/>\nImmunology. 2016 Apr;147(4):476-87.<\/p>\n<hr \/>\n<p><!--\u533a\u5207\u308a\u7dda\u3092\u8868\u793a\u3059\u308bHTML\u30bf\u30b0\u3067\u3059--><br \/>\n<!--\u672c\u6587\u6587\u7bc0\u7d42\u4e86\u3000\u3000\u3053\u3053\u307e\u3067\u3092\u4e00\u3064\u306e\u6587\u7ae0\u3068\u3057\u3066\u8907\u88fd\u3057\u3066\u4f7f\u7528\u3057\u3066\u304f\u3060\u3055\u3044\u3002--><\/p>\n<p><!--\u672c\u6587\u6587\u7bc0\u958b\u59cb\u3000\u3000\u3053\u3053\u304b\u3089\u4e00\u3064\u306e\u6587\u7ae0\u3068\u3057\u3066\u8907\u88fd\u3057\u3066\u4f7f\u7528\u3057\u3066\u304f\u3060\u3055\u3044\u3002--><br \/>\n<a href=\"\u3053\u306e\u6587\u7ae0\u3092\u30ea\u30f3\u30af\u5148\u306eURL\u3078\u5909\u66f4\u3057\u3066\u304f\u3060\u3055\u3044\"><!--\u3053\u3053\u304b\u3089\u306e\u6587\u7ae0\u3078\u30ea\u30f3\u30af\u304c\u5f35\u3089\u308c\u307e\u3059\u3002--><a href=\"http:\/\/www.ncbi.nlm.nih.gov\/pubmed\/26506947\">Namba C, Tohyama M, Hanakawa Y, Murakami M, Shirakata Y, Matsumoto T, Suemori K, Ishii N, Hashimoto T, Sayama K.<\/a><\/a><\/a><\/a><\/a><!--\u3053\u3053\u307e\u3067\u306e\u6587\u7ae0\u3078\u30ea\u30f3\u30af\u304c\u5f35\u3089\u308c\u307e\u3059\u3002--><\/a><br \/>\nParaneoplastic pemphigus associated with fatal bronchiolitis obliterans and intractable mucosal erosions: Treatment with cyclosporin in addition to steroid, rituximab and intravenous immunoglobulin.<br \/>\nJ Dermatol. 2016 Apr;43(4):419-22.<\/p>\n<hr \/>\n<p><!--\u533a\u5207\u308a\u7dda\u3092\u8868\u793a\u3059\u308bHTML\u30bf\u30b0\u3067\u3059--><br \/>\n<!--\u672c\u6587\u6587\u7bc0\u7d42\u4e86\u3000\u3000\u3053\u3053\u307e\u3067\u3092\u4e00\u3064\u306e\u6587\u7ae0\u3068\u3057\u3066\u8907\u88fd\u3057\u3066\u4f7f\u7528\u3057\u3066\u304f\u3060\u3055\u3044\u3002--><\/p>\n<p><!--\u672c\u6587\u6587\u7bc0\u958b\u59cb\u3000\u3000\u3053\u3053\u304b\u3089\u4e00\u3064\u306e\u6587\u7ae0\u3068\u3057\u3066\u8907\u88fd\u3057\u3066\u4f7f\u7528\u3057\u3066\u304f\u3060\u3055\u3044\u3002--><br \/>\n<a href=\"\u3053\u306e\u6587\u7ae0\u3092\u30ea\u30f3\u30af\u5148\u306eURL\u3078\u5909\u66f4\u3057\u3066\u304f\u3060\u3055\u3044\"><!--\u3053\u3053\u304b\u3089\u306e\u6587\u7ae0\u3078\u30ea\u30f3\u30af\u304c\u5f35\u3089\u308c\u307e\u3059\u3002--><a href=\"http:\/\/www.ncbi.nlm.nih.gov\/pubmed\/?term=Chamoto+K%2C+Guo+T%2C+Imataki+O%2C+Tanaka+M%2C+Nakatsugawa+M%2C+Ochi+T%2C+Yamashita+Y%2C+Saito+AM%2C+Saito+TI%2C+Butler+MO%2C+Hirano+N.\">Chamoto K, Guo T, Imataki O, Tanaka M, Nakatsugawa M, Ochi T, Yamashita Y, Saito AM, Saito TI, Butler MO, Hirano N.<\/a><\/a><\/a><\/a><\/a><\/a><\/a><!--\u3053\u3053\u307e\u3067\u306e\u6587\u7ae0\u3078\u30ea\u30f3\u30af\u304c\u5f35\u3089\u308c\u307e\u3059\u3002--><\/a><br \/>\nCDR3\u03b2 sequence motifs regulate autoreactivity of human invariant NKT cell receptors.<br \/>\nJ Autoimmun. 2016 Apr;68:39-51.<\/p>\n<hr \/>\n<p><!--\u533a\u5207\u308a\u7dda\u3092\u8868\u793a\u3059\u308bHTML\u30bf\u30b0\u3067\u3059--><br \/>\n<!--\u672c\u6587\u6587\u7bc0\u7d42\u4e86\u3000\u3000\u3053\u3053\u307e\u3067\u3092\u4e00\u3064\u306e\u6587\u7ae0\u3068\u3057\u3066\u8907\u88fd\u3057\u3066\u4f7f\u7528\u3057\u3066\u304f\u3060\u3055\u3044\u3002--><\/p>\n<p><!--\u672c\u6587\u6587\u7bc0\u958b\u59cb\u3000\u3000\u3053\u3053\u304b\u3089\u4e00\u3064\u306e\u6587\u7ae0\u3068\u3057\u3066\u8907\u88fd\u3057\u3066\u4f7f\u7528\u3057\u3066\u304f\u3060\u3055\u3044\u3002--><br \/>\n<a href=\"\u3053\u306e\u6587\u7ae0\u3092\u30ea\u30f3\u30af\u5148\u306eURL\u3078\u5909\u66f4\u3057\u3066\u304f\u3060\u3055\u3044\"><!--\u3053\u3053\u304b\u3089\u306e\u6587\u7ae0\u3078\u30ea\u30f3\u30af\u304c\u5f35\u3089\u308c\u307e\u3059\u3002--><a href=\"http:\/\/www.ncbi.nlm.nih.gov\/pubmed\/27213277\">Guo T, Chamoto K, Nakatsugawa M, Ochi T, Yamashita Y, Anczurowski M, Butler MO, Hirano N.<\/a><\/a><\/a><\/a><\/a><\/a><!--\u3053\u3053\u307e\u3067\u306e\u6587\u7ae0\u3078\u30ea\u30f3\u30af\u304c\u5f35\u3089\u308c\u307e\u3059\u3002--><\/a><br \/>\nMouse and Human CD1d-Self-Lipid Complexes Are Recognized Differently by Murine Invariant Natural Killer T Cell Receptors.<br \/>\nPLoS One. 2016 May 23;11(5):e0156114.<\/p>\n<hr \/>\n<p><!--\u533a\u5207\u308a\u7dda\u3092\u8868\u793a\u3059\u308bHTML\u30bf\u30b0\u3067\u3059--><br \/>\n<!--\u672c\u6587\u6587\u7bc0\u7d42\u4e86\u3000\u3000\u3053\u3053\u307e\u3067\u3092\u4e00\u3064\u306e\u6587\u7ae0\u3068\u3057\u3066\u8907\u88fd\u3057\u3066\u4f7f\u7528\u3057\u3066\u304f\u3060\u3055\u3044\u3002--><\/p>\n<p><!--\u672c\u6587\u6587\u7bc0\u958b\u59cb\u3000\u3000\u3053\u3053\u304b\u3089\u4e00\u3064\u306e\u6587\u7ae0\u3068\u3057\u3066\u8907\u88fd\u3057\u3066\u4f7f\u7528\u3057\u3066\u304f\u3060\u3055\u3044\u3002--><br \/>\n<a href=\"\u3053\u306e\u6587\u7ae0\u3092\u30ea\u30f3\u30af\u5148\u306eURL\u3078\u5909\u66f4\u3057\u3066\u304f\u3060\u3055\u3044\"><!--\u3053\u3053\u304b\u3089\u306e\u6587\u7ae0\u3078\u30ea\u30f3\u30af\u304c\u5f35\u3089\u308c\u307e\u3059\u3002--><a href=\"http:\/\/www.ncbi.nlm.nih.gov\/pubmed\/?term=Casey+NP%2C+Fujiwara+H%2C+Tanimoto+K%2C+Okamoto+S%2C+Mineno+J%2C+Kuzushima+K%2C+Shiku+H%2C+Yasukawa+M.\">Casey NP, Fujiwara H, Tanimoto K, Okamoto S, Mineno J, Kuzushima K, Shiku H, Yasukawa M.<\/a><\/a><\/a><!--\u3053\u3053\u307e\u3067\u306e\u6587\u7ae0\u3078\u30ea\u30f3\u30af\u304c\u5f35\u3089\u308c\u307e\u3059\u3002--><\/a><br \/>\nA Functionally Superior Second-Generation Vector Expressing an Aurora Kinase-A-Specific T-Cell Receptor for Anti-Leukaemia Adoptive Immunotherapy.<br \/>\nPLoS One. 2016 Jun 7;11(6):e0156896.<\/p>\n<hr \/>\n<p><!--\u533a\u5207\u308a\u7dda\u3092\u8868\u793a\u3059\u308bHTML\u30bf\u30b0\u3067\u3059--><br \/>\n<!--\u672c\u6587\u6587\u7bc0\u7d42\u4e86\u3000\u3000\u3053\u3053\u307e\u3067\u3092\u4e00\u3064\u306e\u6587\u7ae0\u3068\u3057\u3066\u8907\u88fd\u3057\u3066\u4f7f\u7528\u3057\u3066\u304f\u3060\u3055\u3044\u3002--><\/p>\n<p><!--\u672c\u6587\u6587\u7bc0\u958b\u59cb\u3000\u3000\u3053\u3053\u304b\u3089\u4e00\u3064\u306e\u6587\u7ae0\u3068\u3057\u3066\u8907\u88fd\u3057\u3066\u4f7f\u7528\u3057\u3066\u304f\u3060\u3055\u3044\u3002--><br \/>\n<a href=\"\u3053\u306e\u6587\u7ae0\u3092\u30ea\u30f3\u30af\u5148\u306eURL\u3078\u5909\u66f4\u3057\u3066\u304f\u3060\u3055\u3044\"><!--\u3053\u3053\u304b\u3089\u306e\u6587\u7ae0\u3078\u30ea\u30f3\u30af\u304c\u5f35\u3089\u308c\u307e\u3059\u3002--><a href=\"http:\/\/www.ncbi.nlm.nih.gov\/pubmed\/?term=Yasuoka+T%2C+Kuwahara+M%2C+Yamada+T%2C+Maruyama+S%2C+Suzuki+J%2C+Taniguchi+M%2C+Yasukawa+M%2C+Yamashita+M.\">Yasuoka T, Kuwahara M, Yamada T, Maruyama S, Suzuki J, Taniguchi M, Yasukawa M, Yamashita M.<\/a><\/a><\/a><!--\u3053\u3053\u307e\u3067\u306e\u6587\u7ae0\u3078\u30ea\u30f3\u30af\u304c\u5f35\u3089\u308c\u307e\u3059\u3002--><\/a><br \/>\nThe Transcriptional Repressor Gfi1 Plays a Critical Role in the Development of NKT1- and NKT2-Type iNKT Cells.<br \/>\nPLoS One. 2016 Jun 10;11(6):e0157395.<\/p>\n<hr \/>\n<p><!--\u533a\u5207\u308a\u7dda\u3092\u8868\u793a\u3059\u308bHTML\u30bf\u30b0\u3067\u3059--><br \/>\n<!--\u672c\u6587\u6587\u7bc0\u7d42\u4e86\u3000\u3000\u3053\u3053\u307e\u3067\u3092\u4e00\u3064\u306e\u6587\u7ae0\u3068\u3057\u3066\u8907\u88fd\u3057\u3066\u4f7f\u7528\u3057\u3066\u304f\u3060\u3055\u3044\u3002--><\/p>\n<p><!--\u672c\u6587\u6587\u7bc0\u958b\u59cb\u3000\u3000\u3053\u3053\u304b\u3089\u4e00\u3064\u306e\u6587\u7ae0\u3068\u3057\u3066\u8907\u88fd\u3057\u3066\u4f7f\u7528\u3057\u3066\u304f\u3060\u3055\u3044\u3002--><br \/>\n<a href=\"\u3053\u306e\u6587\u7ae0\u3092\u30ea\u30f3\u30af\u5148\u306eURL\u3078\u5909\u66f4\u3057\u3066\u304f\u3060\u3055\u3044\"><!--\u3053\u3053\u304b\u3089\u306e\u6587\u7ae0\u3078\u30ea\u30f3\u30af\u304c\u5f35\u3089\u308c\u307e\u3059\u3002--><a href=\"https:\/\/www.ncbi.nlm.nih.gov\/pubmed\/27091408\">Tanaka H, Fujiwara H, Ochi F, Tanimoto K, Casey N, Okamoto S, Mineno J, Kuzushima K, Shiku H, Sugiyama T, Barrett J, Yasukawa M.<\/a><\/a><\/a><\/a><\/a><\/a><\/a><!--\u3053\u3053\u307e\u3067\u306e\u6587\u7ae0\u3078\u30ea\u30f3\u30af\u304c\u5f35\u3089\u308c\u307e\u3059\u3002--><\/a><br \/>\nDevelopment of engineered T cells expressing a chimeric CD16-CD3\u03b6 receptor to improve the clinical efficacy of mogamulizumab therapy against adult T cell leukemia.<br \/>\nClin Cancer Res. 2016 sep 1;22(17):4405-16.<\/p>\n<hr \/>\n<p><!--\u533a\u5207\u308a\u7dda\u3092\u8868\u793a\u3059\u308bHTML\u30bf\u30b0\u3067\u3059--><br \/>\n<!--\u672c\u6587\u6587\u7bc0\u7d42\u4e86\u3000\u3000\u3053\u3053\u307e\u3067\u3092\u4e00\u3064\u306e\u6587\u7ae0\u3068\u3057\u3066\u8907\u88fd\u3057\u3066\u4f7f\u7528\u3057\u3066\u304f\u3060\u3055\u3044\u3002--><\/p>\n<p><!--\u672c\u6587\u6587\u7bc0\u958b\u59cb\u3000\u3000\u3053\u3053\u304b\u3089\u4e00\u3064\u306e\u6587\u7ae0\u3068\u3057\u3066\u8907\u88fd\u3057\u3066\u4f7f\u7528\u3057\u3066\u304f\u3060\u3055\u3044\u3002--><br \/>\n<a href=\"\u3053\u306e\u6587\u7ae0\u3092\u30ea\u30f3\u30af\u5148\u306eURL\u3078\u5909\u66f4\u3057\u3066\u304f\u3060\u3055\u3044\"><!--\u3053\u3053\u304b\u3089\u306e\u6587\u7ae0\u3078\u30ea\u30f3\u30af\u304c\u5f35\u3089\u308c\u307e\u3059\u3002--><a href=\"https:\/\/www.ncbi.nlm.nih.gov\/pubmed\/?term=Kuwahara+M%2C+Ise+W%2C+Ochi+M%2C+Suzuki+J%2C+Kometani+K%2C+Maruyama+S%2C+Izumoto+M%2C+Matsumoto+A%2C+Takemori+N%2C+Takemori+A%2C+Shinoda+K%2C+Nakayama+T%2C+Ohara+O%2C+Yasukawa+M%2C+Sawasaki+T%2C+Kurosaki+T%2C+Yamashita+M.\">Kuwahara M, Ise W, Ochi M, Suzuki J, Kometani K, Maruyama S, Izumoto M, Matsumoto A, Takemori N, Takemori A, Shinoda K, Nakayama T, Ohara O, Yasukawa M, Sawasaki T, Kurosaki T, Yamashita M.<\/a><!--\u3053\u3053\u307e\u3067\u306e\u6587\u7ae0\u3078\u30ea\u30f3\u30af\u304c\u5f35\u3089\u308c\u307e\u3059\u3002--><\/a><br \/>\nBach2-Batf interactions control Th2-type immune response by regulating the IL-4 amplification loop.<br \/>\nNat Commun. 2016 sep 1;7:12596.<\/p>\n<hr \/>\n<p><!--\u533a\u5207\u308a\u7dda\u3092\u8868\u793a\u3059\u308bHTML\u30bf\u30b0\u3067\u3059--><br \/>\n<!--\u672c\u6587\u6587\u7bc0\u7d42\u4e86\u3000\u3000\u3053\u3053\u307e\u3067\u3092\u4e00\u3064\u306e\u6587\u7ae0\u3068\u3057\u3066\u8907\u88fd\u3057\u3066\u4f7f\u7528\u3057\u3066\u304f\u3060\u3055\u3044\u3002--><\/p>\n<p><!--\u672c\u6587\u6587\u7bc0\u958b\u59cb\u3000\u3000\u3053\u3053\u304b\u3089\u4e00\u3064\u306e\u6587\u7ae0\u3068\u3057\u3066\u8907\u88fd\u3057\u3066\u4f7f\u7528\u3057\u3066\u304f\u3060\u3055\u3044\u3002--><br \/>\n<a href=\"\u3053\u306e\u6587\u7ae0\u3092\u30ea\u30f3\u30af\u5148\u306eURL\u3078\u5909\u66f4\u3057\u3066\u304f\u3060\u3055\u3044\"><!--\u3053\u3053\u304b\u3089\u306e\u6587\u7ae0\u3078\u30ea\u30f3\u30af\u304c\u5f35\u3089\u308c\u307e\u3059\u3002--><a href=\"https:\/\/www.ncbi.nlm.nih.gov\/pubmed\/?term=Kagoya+Y%2C+Nakatsugawa+M%2C+Yamashita+Y%2C+Ochi+T%2C+Guo+T%2C+Anczurowski+M%2C+Saso+K%2C+Butler+MO%2C+Arrowsmith+CH%2C+Hirano+N.\">Kagoya Y, Nakatsugawa M, Yamashita Y, Ochi T, Guo T, Anczurowski M, Saso K, Butler MO, Arrowsmith CH, Hirano N.<\/a><!--\u3053\u3053\u307e\u3067\u306e\u6587\u7ae0\u3078\u30ea\u30f3\u30af\u304c\u5f35\u3089\u308c\u307e\u3059\u3002--><\/a><br \/>\nBET bromodomain inhibition enhances T cell persistence and function in adoptive immunotherapy models.<br \/>\nJ Clin Invest. 2016 Sep 1;126(9):3479-94.<\/p>\n<hr \/>\n<p><!--\u533a\u5207\u308a\u7dda\u3092\u8868\u793a\u3059\u308bHTML\u30bf\u30b0\u3067\u3059--><br \/>\n<!--\u672c\u6587\u6587\u7bc0\u7d42\u4e86\u3000\u3000\u3053\u3053\u307e\u3067\u3092\u4e00\u3064\u306e\u6587\u7ae0\u3068\u3057\u3066\u8907\u88fd\u3057\u3066\u4f7f\u7528\u3057\u3066\u304f\u3060\u3055\u3044\u3002--><\/p>\n<p><!--\u672c\u6587\u6587\u7bc0\u958b\u59cb\u3000\u3000\u3053\u3053\u304b\u3089\u4e00\u3064\u306e\u6587\u7ae0\u3068\u3057\u3066\u8907\u88fd\u3057\u3066\u4f7f\u7528\u3057\u3066\u304f\u3060\u3055\u3044\u3002--><br \/>\n<a href=\"\u3053\u306e\u6587\u7ae0\u3092\u30ea\u30f3\u30af\u5148\u306eURL\u3078\u5909\u66f4\u3057\u3066\u304f\u3060\u3055\u3044\"><!--\u3053\u3053\u304b\u3089\u306e\u6587\u7ae0\u3078\u30ea\u30f3\u30af\u304c\u5f35\u3089\u308c\u307e\u3059\u3002--><a href=\"https:\/\/www.ncbi.nlm.nih.gov\/pubmed\/27658741\">Adnan E, Matsumoto T, Ishizaki J, Onishi S, Suemori K, Yasukawa M, Hasegawa H.<\/a><!--\u3053\u3053\u307e\u3067\u306e\u6587\u7ae0\u3078\u30ea\u30f3\u30af\u304c\u5f35\u3089\u308c\u307e\u3059\u3002--><\/a><br \/>\nHuman tolerogenic dendritic cells generated with protein kinase C inhibitor are optimal for functional regulatory T cell induction &#8211; A comparative study.<br \/>\nClin Immunol. 2016 sep 19 pii:S1521-6616(16)30391-6.<\/p>\n<hr \/>\n<p><!--\u533a\u5207\u308a\u7dda\u3092\u8868\u793a\u3059\u308bHTML\u30bf\u30b0\u3067\u3059--><br \/>\n<!--\u672c\u6587\u6587\u7bc0\u7d42\u4e86\u3000\u3000\u3053\u3053\u307e\u3067\u3092\u4e00\u3064\u306e\u6587\u7ae0\u3068\u3057\u3066\u8907\u88fd\u3057\u3066\u4f7f\u7528\u3057\u3066\u304f\u3060\u3055\u3044\u3002--><\/p>\n<p><!--\u672c\u6587\u6587\u7bc0\u958b\u59cb\u3000\u3000\u3053\u3053\u304b\u3089\u4e00\u3064\u306e\u6587\u7ae0\u3068\u3057\u3066\u8907\u88fd\u3057\u3066\u4f7f\u7528\u3057\u3066\u304f\u3060\u3055\u3044\u3002--><br \/>\n<a href=\"\u3053\u306e\u6587\u7ae0\u3092\u30ea\u30f3\u30af\u5148\u306eURL\u3078\u5909\u66f4\u3057\u3066\u304f\u3060\u3055\u3044\"><!--\u3053\u3053\u304b\u3089\u306e\u6587\u7ae0\u3078\u30ea\u30f3\u30af\u304c\u5f35\u3089\u308c\u307e\u3059\u3002--><a href=\"https:\/\/www.ncbi.nlm.nih.gov\/pubmed\/?term=Yamanouchi+J%2C+Hato+T%2C+Shiraishi+S%2C+Takeuchi+K%2C+Yakushijin+Y%2C+Yasukawa+M.\">Yamanouchi J, Hato T, Shiraishi S, Takeuchi K, Yakushijin Y, Yasukawa M.<\/a><!--\u3053\u3053\u307e\u3067\u306e\u6587\u7ae0\u3078\u30ea\u30f3\u30af\u304c\u5f35\u3089\u308c\u307e\u3059\u3002--><\/a><br \/>\nVancomycin-induced Immune Thrombocytopenia Proven by the Detection of Vancomycin-dependent Anti-platelet Antibody with Flow Cytometry.<br \/>\nIntern Med. 2016;55(20):3035-3038.<\/p>\n<hr \/>\n<p><!--\u533a\u5207\u308a\u7dda\u3092\u8868\u793a\u3059\u308bHTML\u30bf\u30b0\u3067\u3059--><br \/>\n<!--\u672c\u6587\u6587\u7bc0\u7d42\u4e86\u3000\u3000\u3053\u3053\u307e\u3067\u3092\u4e00\u3064\u306e\u6587\u7ae0\u3068\u3057\u3066\u8907\u88fd\u3057\u3066\u4f7f\u7528\u3057\u3066\u304f\u3060\u3055\u3044\u3002--><\/p>\n<p><!--\u672c\u6587\u6587\u7bc0\u958b\u59cb\u3000\u3000\u3053\u3053\u304b\u3089\u4e00\u3064\u306e\u6587\u7ae0\u3068\u3057\u3066\u8907\u88fd\u3057\u3066\u4f7f\u7528\u3057\u3066\u304f\u3060\u3055\u3044\u3002--><br \/>\n<a href=\"\u3053\u306e\u6587\u7ae0\u3092\u30ea\u30f3\u30af\u5148\u306eURL\u3078\u5909\u66f4\u3057\u3066\u304f\u3060\u3055\u3044\"><!--\u3053\u3053\u304b\u3089\u306e\u6587\u7ae0\u3078\u30ea\u30f3\u30af\u304c\u5f35\u3089\u308c\u307e\u3059\u3002--><a href=\"https:\/\/www.ncbi.nlm.nih.gov\/pubmed\/?term=Guo+T%2C+Ochi+T%2C+Nakatsugawa+M%2C+Kagoya+Y%2C+Anczurowski+M%2C+Wang+CH%2C+Rahman+MA%2C+Saso+K%2C+Butler+MO%2C+Hirano+N\">Guo T, Ochi T, Nakatsugawa M, Kagoya Y, Anczurowski M, Wang CH, Rahman MA, Saso K, Butler MO, Hirano N<\/a><!--\u3053\u3053\u307e\u3067\u306e\u6587\u7ae0\u3078\u30ea\u30f3\u30af\u304c\u5f35\u3089\u308c\u307e\u3059\u3002--><\/a><br \/>\nGenerating De Novo Antigen-specific Human T Cell Receptors by Retroviral Transduction of Centric Hemichain.<br \/>\nJ Vis Exp. 2016 Oct 25;(116).<\/p>\n<hr \/>\n<p><!--\u533a\u5207\u308a\u7dda\u3092\u8868\u793a\u3059\u308bHTML\u30bf\u30b0\u3067\u3059--><br \/>\n<!--\u672c\u6587\u6587\u7bc0\u7d42\u4e86\u3000\u3000\u3053\u3053\u307e\u3067\u3092\u4e00\u3064\u306e\u6587\u7ae0\u3068\u3057\u3066\u8907\u88fd\u3057\u3066\u4f7f\u7528\u3057\u3066\u304f\u3060\u3055\u3044\u3002--><\/p>\n<p><!--\u672c\u6587\u6587\u7bc0\u958b\u59cb\u3000\u3000\u3053\u3053\u304b\u3089\u4e00\u3064\u306e\u6587\u7ae0\u3068\u3057\u3066\u8907\u88fd\u3057\u3066\u4f7f\u7528\u3057\u3066\u304f\u3060\u3055\u3044\u3002--><br \/>\n<a href=\"\u3053\u306e\u6587\u7ae0\u3092\u30ea\u30f3\u30af\u5148\u306eURL\u3078\u5909\u66f4\u3057\u3066\u304f\u3060\u3055\u3044\"><!--\u3053\u3053\u304b\u3089\u306e\u6587\u7ae0\u3078\u30ea\u30f3\u30af\u304c\u5f35\u3089\u308c\u307e\u3059\u3002--><a href=\"https:\/\/www.ncbi.nlm.nih.gov\/pubmed\/?term=Yamada+T%2C+Kanoh+M%2C+Nabe+S%2C+Yasuoka+T%2C+Suzuki+J%2C+Matsumoto+A%2C+Kuwahara+M%2C+Maruyama+S%2C+Fujimoto+T%2C+Sakisuka+R%2C+Yasukawa+M%2C+Yamashita+M.\">Yamada T, Kanoh M, Nabe S, Yasuoka T, Suzuki J, Matsumoto A, Kuwahara M, Maruyama S, Fujimoto T, Sakisuka R, Yasukawa M, Yamashita M.<\/a><!--\u3053\u3053\u307e\u3067\u306e\u6587\u7ae0\u3078\u30ea\u30f3\u30af\u304c\u5f35\u3089\u308c\u307e\u3059\u3002--><\/a><br \/>\nMenin Plays a Critical Role in the Regulation of the Antigen-Specific CD8+ T Cell Response upon Listeria Infection.<br \/>\nJ Immunol. 2016 Nov 15;197(10):4079-4089.<\/p>\n<hr \/>\n<p><!--\u533a\u5207\u308a\u7dda\u3092\u8868\u793a\u3059\u308bHTML\u30bf\u30b0\u3067\u3059--><br 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