{"id":255,"date":"2015-06-26T16:31:46","date_gmt":"2015-06-26T07:31:46","guid":{"rendered":"http:\/\/seki1.sakura.ne.jp\/ehime_med2\/?page_id=255"},"modified":"2019-01-18T20:18:15","modified_gmt":"2019-01-18T11:18:15","slug":"heartfailure","status":"publish","type":"page","link":"https:\/\/www.m.ehime-u.ac.jp\/school\/int.med2\/course\/circulatory_organ\/heartfailure\/","title":{"rendered":"\u5fc3\u4e0d\u5168\u30c1\u30fc\u30e0"},"content":{"rendered":"

 <\/p>\n

\u5fc3\u4e0d\u5168\u30c1\u30fc\u30e0\u306e\u53d6\u308a\u7d44\u307f\u306b\u3064\u3044\u3066<\/h2>\n

\u6211\u3005\u3001\u5fc3\u4e0d\u5168\u30c1\u30fc\u30e0\u306f\u5fc3\u4e0d\u5168\u60a3\u8005\u3092\u5bfe\u8c61\u306b\u96c6\u5b66\u7684\u306a\u8a3a\u7642\u3092\u63d0\u4f9b\u3059\u3079\u304f\u3001\u65e5\u3005\u52aa\u529b\u3057\u3066\u304a\u308a\u307e\u3059\u3002<\/p>\n

\u7279\u306b\u4ed6\u306e\u533b\u7642\u6a5f\u95a2\u304b\u3089\u7d39\u4ecb\u3057\u3066\u3044\u305f\u3060\u3044\u305f\u85ac\u5264\u6cbb\u7642\u62b5\u6297\u6027\u306e\u96e3\u6cbb\u6027\u5fc3\u4e0d\u5168\u60a3\u8005\u306b\u5bfe\u3057\u3066\u306f\u3001\u307e\u305a\u975e\u4fb5\u8972\u7684\u306b\u5fc3\u30a8\u30b3\u30fc\u30c1\u30fc\u30e0\u306b\u3088\u308b\u30cf\u30a4\u30a8\u30f3\u30c9\u30fb\u30a8\u30b3\u30fc\u3092\u99c6\u4f7f\u3057\u305f\u5de6\u5ba4\u540c\u671f\u4e0d\u5168\u3092\u542b\u3081\u305f\u5fc3\u6a5f\u80fd\u306e\u8a73\u7d30\u306a\u8a55\u4fa1\u3092\u884c\u3044\u3001\u5fc3\u81d3\u9020\u5f71MRI\u306b\u3088\u308b\u5fc3\u7b4b\u30c0\u30e1\u30fc\u30b8\u306e\u8a55\u4fa1\u3001NT-proBNP\u306a\u3069\u306e\u30de\u30eb\u30c1\u30d0\u30a4\u30aa\u30de\u30fc\u30ab\u30fc\u30fb\u30a2\u30bb\u30b9\u30e1\u30f3\u30c8\u306b\u3088\u308a\u91cd\u75c7\u5ea6\u8a55\u4fa1\u304a\u3088\u3073\u30ea\u30b9\u30af\u306e\u5c64\u5225\u5316\u3092\u884c\u3063\u3066\u304a\u308a\u307e\u3059\u3002<\/p>\n

\u4fb5\u8972\u7684\u306b\u306f\u30b9\u30ef\u30f3\u30ac\u30f3\u30c4\u30fb\u30ab\u30c6\u30fc\u30c6\u30eb\u306b\u3088\u308b\u8840\u884c\u52d5\u614b\u306e\u8a55\u4fa1\u306b\u52a0\u3048\u3001\u307b\u307c\u5168\u4f8b\u306b\u304a\u3044\u3066\u5de6\u5ba4\u5fc3\u7b4b\u3088\u308a\u5fc3\u7b4b\u751f\u691c\u3092\u65bd\u884c\u3057\u3001\u7d44\u7e54\u5b66\u7684\u306a\u8a3a\u65ad\u304a\u3088\u3073\u5fc3\u7b4b\u30ea\u30e2\u30c7\u30ea\u30f3\u30b0\u306e\u8a55\u4fa1\u3092\u3057\u3066\u304a\u308a\u307e\u3059\u3002\u3053\u308c\u3089\u306e\u591a\u9762\u7684\u306a\u30c7\u30fc\u30bf\u3092\u3082\u3068\u306b\u3001\u591a\u7a2e\u306e\u5faa\u74b0\u4f5c\u52d5\u85ac\u3092\u500b\u3005\u306e\u60a3\u8005\u306b\u5fdc\u3058\u3066\u5fae\u8abf\u6574\u3057\u305f\u4e0a\u3067\u3001\u5fc5\u8981\u3067\u3042\u308c\u3070\u975e\u85ac\u7269\u6cbb\u7642\uff08\u5fc3\u81d3\u518d\u540c\u671f\u7642\u6cd5\uff08CRT\uff09\u30fb\u690d\u3048\u8fbc\u307f\u578b\u9664\u7d30\u52d5\u5668\uff08ICD\uff09\u30fb\u5728\u5b85\u9178\u7d20\u7642\u6cd5\u30fb\u967d\u5727\u63db\u6c17\u7642\u6cd5\u30fb\u50e7\u5e3d\u5f01\u5f62\u6210\u8853\u304a\u3088\u3073\u5de6\u5ba4\u5f62\u6210\u8853\u30fb\u6301\u7d9a\u578b\u8840\u6db2\u900f\u6790\uff09\u3092\u30bf\u30a4\u30df\u30f3\u30b0\u3092\u9038\u3059\u308b\u3053\u3068\u306a\u304f\u8e8a\u8e87\u305b\u305a\u5c0e\u5165\u3057\u3066\u304a\u308a\u307e\u3059\u3002<\/p>\n

\u3053\u308c\u3089\u306e\u96c6\u5b66\u7684\u6cbb\u7642\u306b\u3088\u308a\u5fc3\u4e0d\u5168\u60a3\u8005\u306b\u304a\u3051\u308b1\u5e74\u6b7b\u4ea1\u73875\uff05\u672a\u6e80\u30015\u5e74\u6b7b\u4ea1\u738730\uff05\u672a\u6e80\u3068\u826f\u597d\u306a\u6210\u679c\u304c\u5f97\u3089\u308c\u3066\u304a\u308a\u307e\u3059\u3002\u81e8\u5e8a\u7814\u7a76\u3067\u306f\u611b\u5a9b\u770c\u4e0b16\u533b\u7642\u6a5f\u95a2\u306e\u53c2\u52a0\u306e\u3082\u3068web\u00a0site \u30ec\u30b8\u30b9\u30c8\u30ea\u30fc\u30b7\u30b9\u30c6\u30e0\u3092\u7528\u3044\u305f\u6162\u6027\u5fc3\u4e0d\u5168\u60a3\u8005\u306e\u767b\u9332\u89b3\u5bdf\u7814\u7a76\u304c\u73fe\u5728\u9032\u884c\u4e2d\u3067\u3059\u3002<\/p>\n

\u3053\u306e\u7814\u7a76\u3067\u306f\u611b\u5a9b\u770c\u306b\u304a\u3051\u308b\u5fc3\u4e0d\u5168\u60a3\u8005\u306e\u81e8\u5e8a\u50cf\u3084\u6cbb\u7642\u5185\u5bb9\u306a\u3069\u5b9f\u614b\u3092\u660e\u78ba\u306b\u3059\u308b\u3053\u3068\u3067\u3001\u5b9f\u969b\u306e\u60a3\u8005\u50cf\u306b\u5373\u3057\u305f\u4e88\u5f8c\u4e88\u6e2c\u306e\u305f\u3081\u306e\u81e8\u5e8a\u30de\u30fc\u30ab\u30fc\u3084\u85ac\u7269\u304a\u3088\u3073\u975e\u85ac\u7269\u6cbb\u7642\u3092\u542b\u3080\u5fc3\u4e0d\u5168\u306b\u5bfe\u3059\u308b\u6cbb\u7642\u6cd5\u306e\u6709\u52b9\u6027\u5224\u5b9a\u3001\u6cbb\u7642\u52b9\u679c\u306e\u898f\u5b9a\u56e0\u5b50\u3092\u660e\u3089\u304b\u306b\u3059\u308b\u3053\u3068\u3092\u76ee\u7684\u3068\u3057\u3066\u304a\u308a\u3001\u3053\u306e\u7814\u7a76\u306e\u6210\u679c\u304c\u5fc5\u305a\u611b\u5a9b\u770c\u306e\u5fc3\u4e0d\u5168\u60a3\u8005\u306b\u30d5\u30a3\u30fc\u30c9\u30d0\u30c3\u30af\u3067\u304d\u308b\u3082\u306e\u3068\u78ba\u4fe1\u3057\u3066\u304a\u308a\u307e\u3059\u3002<\/p>\n

\u307e\u305f\u5fc3\u4e0d\u5168\u60a3\u8005\u306e\u30de\u30eb\u30c1\u30d0\u30a4\u30aa\u30de\u30fc\u30ab\u30fc\u30fb\u30a2\u30bb\u30b9\u30e1\u30f3\u30c8\u3068\u3057\u3066BNP\u306a\u3069\u306e\u5e83\u304f\u8a8d\u77e5\u3055\u308c\u305f\u30de\u30fc\u30ab\u30fc\u306e\u307f\u306a\u3089\u305a\u3001IL-6\u3084TNF-\u03b1\u306a\u3069\u306e\u708e\u75c7\u6027\u30b5\u30a4\u30c8\u30ab\u30a4\u30f3\u3084\u30b5\u30a4\u30c8\u30ab\u30a4\u30f3\u95a2\u9023\u56e0\u5b50\u3092\u7d44\u307f\u5408\u308f\u305b\u308b\u3053\u3068\u306b\u3088\u308a\u3001\u3088\u308a\u8a73\u7d30\u306a\u6cbb\u7642\u52b9\u679c\u5224\u5b9a\u304a\u3088\u3073\u30ea\u30b9\u30af\u5c64\u5225\u5316\u304c\u53ef\u80fd\u306b\u306a\u308b\u3053\u3068\u3092\u5831\u544a\u3057\u3066\u304a\u308a\u307e\u3059(J Am Coll Cardiol 37:412-417, 2001)\u3002\u7279\u306b\u4e0d\u5168\u5fc3\u7b4b\u306b\u304a\u3051\u308b\u7dda\u7dad\u5316\u3001\u3082\u3046\u5c11\u3057\u8a73\u7d30\u306b\u8a00\u3048\u3070\u7d30\u80de\u5916\u30de\u30c8\u30ea\u30c3\u30af\u30b9\u30ea\u30e2\u30c7\u30ea\u30f3\u30b0\u306b\u6df1\u304f\u95a2\u4fc2\u3057\u3066\u3044\u308b\u30de\u30c8\u30ea\u30c3\u30af\u30b9\u30e1\u30bf\u30ed\u30d7\u30ed\u30c6\u30a2\u30fc\u30bc(MMP)\u306f\u81e8\u5e8a\u4e0a\u6709\u7528\u3067\u3042\u308a\u3001\u8840\u4e2dMMP-3\u6fc3\u5ea6\u304c\u9ad8\u3044\u60a3\u8005\u306f\u5c06\u6765\u7684\u306a\u5fc3\u4e8b\u6545\u3092\u767a\u75c7\u3059\u308b\u7387\u304c\u9ad8\u3044\u3053\u3068\u3082\u5831\u544a\u3057\u3066\u304a\u308a\u307e\u3059\u3002(J Cardiac Fail 13:752-758, 2007)\u3002<\/p>\n

\u00a0<\/div>\n

\"\u51a0\u9759\u8108\u6d1e\u5185\u306eMMP\u6fc3\u5ea6\"\u3053\u308c\u3089\u306e\u60a3\u8005\u3067\u306f\u51a0\u9759\u8108\u6d1e\u5185\u306eMMP\u6fc3\u5ea6\u3082\u4e0a\u6607\u3057\u3066\u304a\u308a\u3001\u751f\u691c\u5fc3\u7b4b\u6a19\u672c\u3088\u308a\u96fb\u5b50\u9855\u5fae\u93e1\u3092\u7528\u3044\u305f\u7d30\u80de\u5916\u30de\u30c8\u30ea\u30c3\u30af\u30b9\u306e\u30b3\u30e9\u30fc\u30b2\u30f3\u30fb\u30bf\u30a4\u30d4\u30f3\u30b0\u3092\u884c\u3046\u3068MMP\u4f4e\u5024\u60a3\u8005\u306b\u6bd4\u3057\u3066\u592a\u304f\u56fa\u3044I\u578b\u30b3\u30e9\u30fc\u30b2\u30f3\u304c\u5897\u751f\u3057\u3066\u3044\u308b\u306e\u304c\u3088\u304f\u308f\u304b\u308a\u307e\u3059\u3002<\/p>\n

\u00a0<\/div>\n

\u5fc3\u4e0d\u5168\u306f\u3042\u3089\u3086\u308b\u5fc3\u75be\u60a3\u306e\u7d42\u672b\u50cf\u3067\u3042\u308a\u3001\u5168\u8eab\u7684\u306a\u75c7\u5019\u7fa4\u3067\u3059\u3002<\/p>\n

\u3067\u3059\u304b\u30891\u4eba1\u4eba\u306e\u5fc3\u4e0d\u5168\u60a3\u8005\u304c\u5168\u304f\u9055\u3046\u81e8\u5e8a\u50cf\u3092\u5448\u3057\u3066\u304a\u308a\u3001\u500b\u3005\u306e\u81e8\u5e8a\u50cf\u306b\u5373\u3057\u305f\u591a\u9762\u7684\u30a2\u30d7\u30ed\u30fc\u30c1\u3092\u3059\u308b\u3068\u3068\u3082\u306b\u73fe\u5728\u3060\u3051\u3067\u306a\u304f5\u5e74\u5148\u300110\u5e74\u5148\u306e\u4e88\u5f8c\u3092\u307f\u3053\u3057\u305f\u96c6\u5b66\u7684\u6cbb\u7642\u3092\u884c\u3046\u3053\u3068\u304c\u6211\u3005\u3001\u5fc3\u4e0d\u5168\u30c1\u30fc\u30e0\u306e\u30e2\u30c3\u30c8\u30fc\u3067\u3059\u3002<\/p>\n","protected":false},"excerpt":{"rendered":"

  \u5fc3\u4e0d\u5168\u30c1\u30fc\u30e0\u306e\u53d6\u308a\u7d44\u307f\u306b\u3064\u3044\u3066 \u6211\u3005\u3001\u5fc3\u4e0d\u5168\u30c1\u30fc\u30e0\u306f\u5fc3\u4e0d\u5168\u60a3\u8005\u3092\u5bfe\u8c61\u306b\u96c6\u5b66\u7684\u306a\u8a3a\u7642\u3092\u63d0\u4f9b\u3059\u3079\u304f\u3001\u65e5\u3005\u52aa\u529b\u3057\u3066\u304a\u308a\u307e\u3059\u3002 \u7279\u306b\u4ed6\u306e\u533b\u7642\u6a5f\u95a2\u304b\u3089\u7d39\u4ecb\u3057\u3066\u3044\u305f\u3060\u3044\u305f\u85ac\u5264\u6cbb\u7642\u62b5\u6297\u6027\u306e\u96e3\u6cbb\u6027\u5fc3\u4e0d\u5168\u60a3\u8005\u306b\u5bfe\u3057\u3066\u306f\u3001\u307e\u305a […]<\/p>\n","protected":false},"author":2,"featured_media":983,"parent":47,"menu_order":4,"comment_status":"open","ping_status":"open","template":"","meta":{"footnotes":""},"class_list":["post-255","page","type-page","status-publish","has-post-thumbnail","hentry"],"aioseo_notices":[],"_links":{"self":[{"href":"https:\/\/www.m.ehime-u.ac.jp\/school\/int.med2\/wp-json\/wp\/v2\/pages\/255","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/www.m.ehime-u.ac.jp\/school\/int.med2\/wp-json\/wp\/v2\/pages"}],"about":[{"href":"https:\/\/www.m.ehime-u.ac.jp\/school\/int.med2\/wp-json\/wp\/v2\/types\/page"}],"author":[{"embeddable":true,"href":"https:\/\/www.m.ehime-u.ac.jp\/school\/int.med2\/wp-json\/wp\/v2\/users\/2"}],"replies":[{"embeddable":true,"href":"https:\/\/www.m.ehime-u.ac.jp\/school\/int.med2\/wp-json\/wp\/v2\/comments?post=255"}],"version-history":[{"count":2,"href":"https:\/\/www.m.ehime-u.ac.jp\/school\/int.med2\/wp-json\/wp\/v2\/pages\/255\/revisions"}],"predecessor-version":[{"id":2704,"href":"https:\/\/www.m.ehime-u.ac.jp\/school\/int.med2\/wp-json\/wp\/v2\/pages\/255\/revisions\/2704"}],"up":[{"embeddable":true,"href":"https:\/\/www.m.ehime-u.ac.jp\/school\/int.med2\/wp-json\/wp\/v2\/pages\/47"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/www.m.ehime-u.ac.jp\/school\/int.med2\/wp-json\/wp\/v2\/media\/983"}],"wp:attachment":[{"href":"https:\/\/www.m.ehime-u.ac.jp\/school\/int.med2\/wp-json\/wp\/v2\/media?parent=255"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}