{"id":39,"date":"2014-08-27T14:37:36","date_gmt":"2014-08-27T05:37:36","guid":{"rendered":"http:\/\/www.m.ehime-u.ac.jp\/school\/mcp\/?page_id=39"},"modified":"2026-01-30T17:58:58","modified_gmt":"2026-01-30T08:58:58","slug":"%e7%a0%94%e7%a9%b6%e5%86%85%e5%ae%b9","status":"publish","type":"page","link":"https:\/\/www.m.ehime-u.ac.jp\/school\/mcp\/?page_id=39","title":{"rendered":"\u7814\u7a76\u5185\u5bb9"},"content":{"rendered":"<h3><strong>\u300c\u751f\u4f53\u96fb\u6c17\u300d\u3092\u518d\u5b9a\u7fa9\u3059\u308b\uff0d\u96fb\u6c17\u4fe1\u53f7\u304c\u3082\u3064\u65b0\u305f\u306a\u5f79\u5272\u3078\u306e\u6311\u6226 (\u4e3b\u306b\u6cb3\u5408)<\/strong><\/h3>\n<p><img loading=\"lazy\" decoding=\"async\" class=\"alignnone wp-image-267\" src=\"https:\/\/www.m.ehime-u.ac.jp\/school\/mcp\/wp-content\/uploads\/2026\/01\/\u8208\u596e\u6027-300x121.jpg\" alt=\"\" width=\"546\" height=\"220\" srcset=\"https:\/\/www.m.ehime-u.ac.jp\/school\/mcp\/wp-content\/uploads\/2026\/01\/\u8208\u596e\u6027-300x121.jpg 300w, https:\/\/www.m.ehime-u.ac.jp\/school\/mcp\/wp-content\/uploads\/2026\/01\/\u8208\u596e\u6027-1024x414.jpg 1024w, https:\/\/www.m.ehime-u.ac.jp\/school\/mcp\/wp-content\/uploads\/2026\/01\/\u8208\u596e\u6027-768x311.jpg 768w, https:\/\/www.m.ehime-u.ac.jp\/school\/mcp\/wp-content\/uploads\/2026\/01\/\u8208\u596e\u6027-1536x622.jpg 1536w, https:\/\/www.m.ehime-u.ac.jp\/school\/mcp\/wp-content\/uploads\/2026\/01\/\u8208\u596e\u6027-2048x829.jpg 2048w\" sizes=\"auto, (max-width: 546px) 100vw, 546px\" \/><\/p>\n<p>\u8133\u6ce2\u3084\u5fc3\u96fb\u56f3\u304b\u3089\u3082\u5206\u304b\u308b\u3088\u3046\u306b\u3001\u79c1\u305f\u3061\u306e\u8eab\u4f53\u306f\u81f3\u308b\u3068\u3053\u308d\u3067\u5fae\u5f31\u306a\u300c\u96fb\u6c17\u4fe1\u53f7\u300d\u3092\u751f\u6210\u3057\u3001\u751f\u547d\u6d3b\u52d5\u3092\u7dad\u6301\u3057\u3066\u3044\u307e\u3059\u3002\u3053\u306e\u96fb\u6c17\u306e\u751f\u6210\u3068\u611f\u77e5\u6a5f\u69cb\u306f\u3001\u9577\u3089\u304f\u795e\u7d4c\u7d30\u80de\u306a\u3069\u3092\u4e2d\u5fc3\u3068\u3057\u3066\u9032\u3081\u3089\u308c\u3001\u305d\u306e\u4e3b\u5f79\u306f\u300c\u96fb\u4f4d\u4f9d\u5b58\u6027\u30a4\u30aa\u30f3\u30c1\u30e3\u30cd\u30eb\u300d\u3068\u3044\u3046\u5206\u5b50\u7fa4\u3067\u3042\u308b\u3053\u3068\u304c\u5206\u304b\u3063\u3066\u3044\u307e\u3059\u3002<\/p>\n<p><img loading=\"lazy\" decoding=\"async\" class=\"alignnone wp-image-264\" src=\"https:\/\/www.m.ehime-u.ac.jp\/school\/mcp\/wp-content\/uploads\/2026\/01\/\u30a4\u30aa\u30f3\u30c1\u30e3\u30cd\u30eb-300x169.jpg\" alt=\"\" width=\"488\" height=\"275\" srcset=\"https:\/\/www.m.ehime-u.ac.jp\/school\/mcp\/wp-content\/uploads\/2026\/01\/\u30a4\u30aa\u30f3\u30c1\u30e3\u30cd\u30eb-300x169.jpg 300w, https:\/\/www.m.ehime-u.ac.jp\/school\/mcp\/wp-content\/uploads\/2026\/01\/\u30a4\u30aa\u30f3\u30c1\u30e3\u30cd\u30eb-1024x576.jpg 1024w, https:\/\/www.m.ehime-u.ac.jp\/school\/mcp\/wp-content\/uploads\/2026\/01\/\u30a4\u30aa\u30f3\u30c1\u30e3\u30cd\u30eb-768x432.jpg 768w, https:\/\/www.m.ehime-u.ac.jp\/school\/mcp\/wp-content\/uploads\/2026\/01\/\u30a4\u30aa\u30f3\u30c1\u30e3\u30cd\u30eb.jpg 1522w\" sizes=\"auto, (max-width: 488px) 100vw, 488px\" \/><\/p>\n<p>\u4e00\u822c\u306b\u96fb\u4f4d\u4f9d\u5b58\u6027\u30a4\u30aa\u30f3\u30c1\u30e3\u30cd\u30eb\u306f\u3001\u7d30\u80de\u306e\u819c\u96fb\u4f4d(\u96fb\u6c17\u4fe1\u53f7)\u3092\u611f\u77e5\u3059\u308b\u96fb\u4f4d\u30bb\u30f3\u30b5\u30fc\u30c9\u30e1\u30a4\u30f3\u3068\u3001\u30a4\u30aa\u30f3\u3092\u900f\u904e\u3059\u308b\u30dd\u30a2\u30c9\u30e1\u30a4\u30f3\u3088\u308a\u69cb\u6210\u3055\u308c\u307e\u3059(\u4e0a\u56f3A)\u3002\u3053\u308c\u306b\u3088\u308a\u7d30\u80de\u306e\u819c\u96fb\u4f4d\u3092\u611f\u3058\u3066\u591a\u69d8\u306a\u30a4\u30aa\u30f3\u3092\u901a\u3059\u3053\u3068\u304c\u51fa\u6765\u308b\u3088\u3046\u306b\u306a\u308a\u307e\u3059\u3002\u305d\u3057\u3066\u3053\u306e\u30a4\u30aa\u30f3\u306e\u900f\u904e\u306f\u307e\u305f\u65b0\u305f\u306a\u819c\u96fb\u4f4d\u5909\u5316\u3092\u751f\u307f\u3001\u7d30\u80de\u306f\u30c0\u30a4\u30ca\u30df\u30c3\u30af\u306a\u300c\u52d5\u304d\u300d\u3092\u793a\u3059\u3088\u3046\u306b\u306a\u308a\u307e\u3059(\u4e0a\u56f3B)\u3002\u3053\u306e\u3053\u3068\u304b\u3089\u3082\u300c\u30a4\u30aa\u30f3\u30c1\u30e3\u30cd\u30eb\uff1d\u819c\u96fb\u4f4d\u300d\u3068\u3044\u3046\u56f3\u5f0f\u304c\u6210\u308a\u7acb\u3064\u3053\u3068\u3082\u3046\u306a\u305a\u3051\u307e\u3059\u3002<\/p>\n<p>\u4e00\u65b9\u3067\u5f8c\u8ff0\u3059\u308b\u3088\u3046\u306b\u3001\u6211\u3005\u306f\u8fd1\u5e74\u306e\u7814\u7a76\u3092\u901a\u3058\u3001\u751f\u4f53\u5185\u306b\u306f\u3053\u306e\u4e0a\u8a18\u306e\u30e1\u30ab\u30cb\u30ba\u30e0\u306b\u3082\u591a\u69d8\u306a\u5f62\u304c\u3042\u308b\u3053\u3068\u3084\u3001\u305d\u308c\u3069\u3053\u308d\u304b\u65e2\u77e5\u306e\u5206\u5b50\u30e2\u30c7\u30eb\u3067\u306f\u8aac\u660e\u3057\u304d\u308c\u306a\u3044\u3001\u5168\u304f\u5225\u306e\u96fb\u4f4d\u611f\u77e5\u30e1\u30ab\u30cb\u30ba\u30e0\u304c\u5b58\u5728\u3057\u3066\u3044\u308b\u3053\u3068\u3082\u898b\u51fa\u3057\u307e\u3057\u305f\u3002 \u672c\u7814\u7a76\u5ba4\u3067\u306f\u3001\u3053\u308c\u307e\u3067\u898b\u904e\u3054\u3055\u308c\u3066\u304d\u305f\u3053\u306e\u300c\u65b0\u305f\u306a\u96fb\u4f4d\u611f\u77e5\u6a5f\u69cb\u300d\u306b\u30b9\u30dd\u30c3\u30c8\u3092\u5f53\u3066\u3001\u7279\u5b9a\u306e\u5668\u5b98\u306b\u7559\u307e\u3089\u305a\u3001\u5e45\u5e83\u3044\u751f\u4f53\u7d44\u7e54\u3092\u5bfe\u8c61\u3068\u3057\u305f\u6a2a\u65ad\u7684\u306a\u89e3\u660e\u3092\u76ee\u6307\u3057\u3066\u3044\u307e\u3059\u3002\u672a\u6765\u306e\u6559\u79d1\u66f8\u306b\u65b0\u305f\u306a\u4e00\u9801\u3092\u52a0\u3048\u308b\u3053\u3068\u3092\u76ee\u6307\u3057\u3066\u3001\u65e5\u3005\u306e\u7814\u7a76\u306b\u53d6\u308a\u7d44\u3093\u3067\u3044\u307e\u3059\u3002<\/p>\n<ol>\n<li>\n<h4><strong>\u795e\u7d4c\u7d30\u80de\u304c\u793a\u3059\u300c\u6d3b\u52d5\u96fb\u4f4d\u300d\u306e\u751f\u6210\u30fb\u611f\u77e5\u6a5f\u69cb\u306b\u3064\u3044\u3066<\/strong><\/h4>\n<\/li>\n<\/ol>\n<p>\u795e\u7d4c\u7d30\u80de\u304c\u793a\u3059\u52d5\u7684\u306a\u819c\u96fb\u4f4d\u5909\u5316\u3068\u3057\u3066\u3001\u6d3b\u52d5\u96fb\u4f4d\u304c\u77e5\u3089\u308c\u3066\u3044\u307e\u3059\u3002\u9ad8\u6821\u751f\u7269\u306e\u6559\u79d1\u66f8\u3067\u3082\u89e6\u308c\u3089\u308c\u3066\u3044\u308b\u901a\u308a\u6d3b\u52d5\u96fb\u4f4d\u306b\u3064\u3044\u3066\u306f\u3001\u96fb\u4f4d\u4f9d\u5b58\u6027Na<sup>+<\/sup>\u30c1\u30e3\u30cd\u30eb\u306e\u30c0\u30a4\u30ca\u30df\u30c3\u30af\u306a\u958b\u53e3\u3001\u307e\u305f\u305d\u308c\u306b\u4f34\u3046\u96fb\u4f4d\u4f9d\u5b58\u6027K<sup>+<\/sup>\u30c1\u30e3\u30cd\u30eb\u306e\u958b\u53e3\u304c\u91cd\u8981\u3067\u3042\u308b\u3053\u3068\u304c\u77e5\u3089\u308c\u3066\u3044\u307e\u3059\u3002\u3057\u304b\u3057\u795e\u7d4c\u7d30\u80de\u306e\u6d3b\u52d5\u5236\u5fa1\u306f\u3053\u308c\u3089\u306e\u30a4\u30aa\u30f3\u30c1\u30e3\u30cd\u30eb\u306e\u307f\u3067\u884c\u308f\u308c\u308b\u308f\u3051\u3067\u306f\u3042\u308a\u307e\u305b\u3093\u3002\u5b9f\u969b\u306b\u6211\u3005\u306f\u3001\u8fd1\u5e74\u5185\u5074\u624b\u7db1\u6838\uff08\u60c5\u52d5\u3084\u5fcc\u907f\u306b\u95a2\u308f\u308b\u8133\u9818\u57df\uff09\u3068\u3088\u3070\u308c\u308b\u90e8\u4f4d\u306b\u304a\u3044\u3066\u3001\u8907\u6570\u306e\u30c1\u30e3\u30cd\u30eb\u304c\u5de7\u5999\u306b\u7d44\u307f\u5408\u308f\u3055\u308b\u3053\u3068\u3067\u3001\u300c\u5206\u5358\u4f4d\u300d\u306e\u9577\u671f\u7684\u306a\u6d3b\u52d5\u5236\u5fa1\u304c\u8907\u6570\u306e\u30a4\u30aa\u30f3\u30c1\u30e3\u30cd\u30eb\u306e\u50cd\u304d\u306b\u3088\u3063\u3066\u53ef\u80fd\u3068\u306a\u308b\u3053\u3068\u3092\u898b\u51fa\u3057\u3066\u3044\u307e\u3059(\u8a73\u7d30\u306b\u3064\u3044\u3066\u306fKawai et al., <em><strong>Sci Adv<\/strong><\/em>, 2025)\u3002\u3053\u306e\u3088\u3046\u306b\u6d3b\u52d5\u96fb\u4f4d\u4e00\u3064\u3092\u3068\u3063\u3066\u3082\u305d\u306e\u5236\u5fa1\u6a5f\u69cb\u306b\u306f\u307e\u3060\u307e\u3060\u77e5\u3089\u308c\u3066\u3044\u306a\u3044\u30e1\u30ab\u30cb\u30ba\u30e0\u304c\u5b58\u5728\u3057\u3066\u3044\u308b\u3068\u601d\u3063\u3066\u3044\u307e\u3059\u3002\u307e\u305f\u3001\u4eca\u5f8c\u306f\u3053\u306e\u3088\u3046\u306a\u795e\u7d4c\u7d30\u80de\u306e\u819c\u96fb\u4f4d\u304c\u6301\u3064\u751f\u7406\u7684\u306a\u610f\u7fa9\u306b\u3064\u3044\u3066\u3082\u3001\u5f93\u6765\u898b\u904e\u3054\u3055\u308c\u3066\u304d\u305f\u30e1\u30ab\u30cb\u30ba\u30e0\u3092\u767a\u6398\u3057\u3066\u3044\u304d\u305f\u3044\u3068\u8003\u3048\u3066\u3044\u307e\u3059\u3002<\/p>\n<p><img loading=\"lazy\" decoding=\"async\" class=\"alignnone wp-image-263\" src=\"https:\/\/www.m.ehime-u.ac.jp\/school\/mcp\/wp-content\/uploads\/2026\/01\/\u96fb\u6c17\u7684\u8208\u596e-300x188.jpg\" alt=\"\" width=\"455\" height=\"285\" srcset=\"https:\/\/www.m.ehime-u.ac.jp\/school\/mcp\/wp-content\/uploads\/2026\/01\/\u96fb\u6c17\u7684\u8208\u596e-300x188.jpg 300w, https:\/\/www.m.ehime-u.ac.jp\/school\/mcp\/wp-content\/uploads\/2026\/01\/\u96fb\u6c17\u7684\u8208\u596e-1024x643.jpg 1024w, https:\/\/www.m.ehime-u.ac.jp\/school\/mcp\/wp-content\/uploads\/2026\/01\/\u96fb\u6c17\u7684\u8208\u596e-768x482.jpg 768w, https:\/\/www.m.ehime-u.ac.jp\/school\/mcp\/wp-content\/uploads\/2026\/01\/\u96fb\u6c17\u7684\u8208\u596e.jpg 1479w\" sizes=\"auto, (max-width: 455px) 100vw, 455px\" \/><\/p>\n<ol start=\"2\">\n<li>\n<h4><strong>\u300c\u975e\u8208\u596e\u6027\u7d30\u80de\u300d\u304c\u3082\u3064\u96fb\u6c17\u4fe1\u53f7\u306e\u610f\u7fa9<\/strong><\/h4>\n<\/li>\n<\/ol>\n<p>\u795e\u7d4c\u7d30\u80de\u3084\u3001\u5fc3\u7b4b\u306a\u3069\u306e\u6d3b\u52d5\u96fb\u4f4d\u3092\u751f\u3058\u308b\u7d30\u80de\u3092\u300c\u8208\u596e\u6027\u7d30\u80de\u300d\u3068\u3044\u3044\u307e\u3059\u3002\u300c\u975e\u8208\u596e\u6027\u7d30\u80de\u300d\u3068\u306f\u6d3b\u52d5\u96fb\u4f4d\u3092\u751f\u3058\u306a\u3044\u7d30\u80de\u3067\u3059\u3002\u3053\u306e\u3088\u3046\u306a\u300c\u975e\u8208\u596e\u6027\u7d30\u80de\u300d\u306f\u3001\u819c\u96fb\u4f4d\u306e\u9855\u8457\u306a\u5909\u52d5\u3053\u305d\u793a\u3055\u306a\u3044\u3082\u306e\u306e\u3001\u7d30\u80de\u819c\u3092\u3082\u3064\u4ee5\u4e0a\u306f\u819c\u96fb\u4f4d\u3092\u6709\u3057\u3066\u3044\u307e\u3059\u3002\u3057\u304b\u3057\u3053\u306e\u3088\u3046\u306a\u300c\u975e\u8208\u596e\u6027\u7d30\u80de\u300d\u304c\u3082\u3064\u819c\u96fb\u4f4d\u306e\u610f\u7fa9\u306f\u8208\u596e\u6027\u7d30\u80de\u3068\u6bd4\u3057\u3066\u3082\u9a5a\u304f\u307b\u3069\u5206\u304b\u3063\u3066\u3044\u307e\u305b\u3093\u3002\u4e00\u65b9\u3067\u3001\u6211\u3005\u306f\u975e\u8208\u596e\u6027\u7d30\u80de\u306e\u3072\u3068\u3064\u3067\u3042\u308b\u7cbe\u5b50\u306b\u304a\u3044\u3066\u3001\u96fb\u4f4d\u4f9d\u5b58\u6027\u30db\u30b9\u30d5\u30a1\u30bf\u30fc\u30bc(VSP)\u3068\u547c\u3070\u308c\u308b\u5206\u5b50\u304c\u6a5f\u80fd\u3057\u3066\u3044\u308b\u3053\u3068\u3092\u521d\u3081\u3066\u793a\u3057\u307e\u3057\u305f(Kawai et al., <em><strong>PNAS<\/strong><\/em>, 2019; Kawai et al., <em><strong>Nat Commun<\/strong><\/em>, 2024\u306a\u3069)\u3002VSP\u306f\u4e0a\u8ff0\u306e\u96fb\u4f4d\u30bb\u30f3\u30b5\u30fc\u30c9\u30e1\u30a4\u30f3\u306b\u30db\u30b9\u30d5\u30a1\u30bf\u30fc\u30bc\u304c\u9023\u7d50\u3057\u3066\u3044\u308b\u3068\u3044\u3046\u6975\u3081\u3066\u72ec\u7279\u306a\u5206\u5b50\u3067\u3059(Murata et al., <strong><em>Nature<\/em><\/strong>, 2006)\u3002\u6211\u3005\u306f\u3001\u7cbe\u5b50\u304c\u305d\u306e\u6210\u719f\u904e\u7a0b\u306b\u304a\u3044\u3066VSP\u3092\u4ecb\u3057\u3066\u819c\u96fb\u4f4d\u3092\u611f\u77e5\u3057\u3001\u6210\u719f\u7cbe\u5b50\u306e\u904b\u52d5\u5236\u5fa1\u306b\u91cd\u8981\u3067\u3042\u308b\u3053\u3068\u3092\u898b\u51fa\u3057\u307e\u3057\u305f\u3002\u307e\u305f\u4e0a\u8a18VSP\u306e\u4ed6\u306b\u3082\u7cbe\u5b50\u306b\u304a\u3051\u308b\u69d8\u3005\u306a\u96fb\u4f4d\u611f\u77e5\u5206\u5b50\u306b\u7740\u76ee\u3057\u7814\u7a76\u3092\u9032\u3081\u3066\u3044\u308b\u307b\u304b\u3001\u514d\u75ab\u7d30\u80de\u306a\u3069\u7cbe\u5b50\u4ee5\u5916\u306e\u975e\u8208\u596e\u6027\u7d30\u80de\u306b\u3082\u30d7\u30ed\u30b8\u30a7\u30af\u30c8\u3092\u62e1\u5f35\u3057\u3066\u3044\u3053\u3046\u3068\u3057\u3066\u3044\u307e\u3059\u3002<\/p>\n<p><img loading=\"lazy\" decoding=\"async\" class=\"alignnone wp-image-266\" src=\"https:\/\/www.m.ehime-u.ac.jp\/school\/mcp\/wp-content\/uploads\/2026\/01\/VSP-255x300.jpg\" alt=\"\" width=\"329\" height=\"387\" srcset=\"https:\/\/www.m.ehime-u.ac.jp\/school\/mcp\/wp-content\/uploads\/2026\/01\/VSP-255x300.jpg 255w, https:\/\/www.m.ehime-u.ac.jp\/school\/mcp\/wp-content\/uploads\/2026\/01\/VSP.jpg 726w\" sizes=\"auto, (max-width: 329px) 100vw, 329px\" \/><\/p>\n<p>&nbsp;<\/p>\n<h3>\u75c5\u614b\u4e0b\u306e\u795e\u7d4c\u751f\u7406\u5b66\u306e\u8af8\u554f\u984c\u306e\u89e3\u6c7a\u306b\u5411\u3051\u3066 &#8211; \u795e\u7d4c\u708e\u75c7\u30fb\u8133\u816b\u760d\u306e\u65b0\u898f\u8a3a\u65ad\u30fb\u6cbb\u7642\u306e\u958b\u767a\u3092\u76ee\u6307\u3057\u3066 (\u4e3b\u306b\u77e2\u91ce)<\/h3>\n<p>\u795e\u7d4c\u7cfb\u306e\u75be\u60a3\u306e\u591a\u304f\u304c\u96e3\u6cbb\u6027\u3067\u3042\u308a\u300121 \u4e16\u7d00\u306e\u4eca\u65e5\u306b\u304a\u3044\u3066\u3082\u3044\u307e\u3060\u306b\u307b\u3068\u3093\u3069\u6cbb\u7642\u6cd5\u304c\u306a\u3044\u3082\u306e\u3082\u3042\u308a\u307e\u3059\u3002\u305d\u308c\u306f\u75be\u60a3\u306e\u539f\u56e0\u304c\u306f\u3063\u304d\u308a\u3057\u306a\u3044\u3053\u3068\u3068\u3068\u3082\u306b\u3001\u305d\u3082\u305d\u3082\u5065\u5e38\u306e\u795e\u7d4c\u7cfb\u306e\u7406\u89e3\u3082\u3001\u3044\u307e\u3060\u4e0d\u5341\u5206\u3067\u3042\u308b\u3053\u3068\u306b\u8d77\u56e0\u3057\u3066\u3044\u308b\u3068\u8003\u3048\u3089\u308c\u307e\u3059\u3002\u5f53\u6559\u5ba4\u3067\u306f\u3053\u3046\u3057\u305f\u554f\u984c\u306e\u89e3\u6c7a\u306b\u5c11\u3057\u3067\u3082\u8cc7\u3059\u308b\u3053\u3068\u3092\u76ee\u6307\u3057\u305f\u7814\u7a76\u3082\u884c\u3063\u3066\u3044\u307e\u3059\u3002<\/p>\n<ol start=\"3\">\n<li>\u30df\u30af\u30ed\u30b0\u30ea\u30a2\u304c\u95a2\u4e0e\u3059\u308b\u795e\u7d4c\u708e\u75c7\u306e\u7406\u89e3\u30fb\u5236\u5fa1\u306b\u5411\u3051\u3066<\/li>\n<\/ol>\n<p>\u795e\u7d4c\u708e\u75c7\u304c\u795e\u7d4c\u7cfb\u75be\u60a3\u306b\u95a2\u4e0e\u3057\u3066\u304a\u308a\u3001\u305d\u308c\u3092\u62c5\u3046\u8133\u5185\u306e\u7d30\u80de\u304c\u30b0\u30ea\u30a2\u7d30\u80de\u306e\u4e00\u3064\u3067\u3042\u308b\u30df\u30af\u30ed\u30b0\u30ea\u30a2\u3067\u3059\u3002\u708e\u75c7\u306f\u751f\u7406\u7684\u306a\u53cd\u5fdc\u3067\u3042\u308b\u305f\u3081\u3001\u3084\u307f\u304f\u3082\u306b\u6291\u5236\u3059\u308c\u3070\u3088\u3044\u3068\u3044\u3046\u3082\u306e\u3067\u306f\u3042\u308a\u307e\u305b\u3093\u304c\u3001\u305d\u308c\u304c\u75be\u60a3\u306e\u6210\u56e0\u3068\u306a\u308b\u5834\u5408\u306b\u306f\u5236\u5fa1\u304c\u5fc5\u8981\u3068\u8003\u3048\u3089\u308c\u308b\u305f\u3081\u3001\u3053\u308c\u307e\u3067\u306b\u795e\u7d4c\u708e\u75c7\u304c\u8d77\u3053\u308b\u3057\u304f\u307f\u306e\u63a2\u6c42\u3001\u305d\u308c\u3092\u5236\u5fa1\u3057\u3046\u308b\u85ac\u5264\u306e\u63a2\u7d22\u3001\u304a\u3088\u3073\u305d\u306e\u6297\u9178\u5316\u7684\u30fb\u6297\u708e\u75c7\u7684\u8ee2\u5199\u56e0\u5b50 NRF2 \u6d3b\u6027\u5316\u5264\u3068\u3057\u3066\u306e\u4f5c\u7528\u6a5f\u5e8f\u89e3\u6790 (Takeda et.al., <em>BBRC<\/em> 2022., Takeda et.al., <em>J. Biochem.<\/em>, 2023) \u3092\u884c\u3063\u3066\u304d\u307e\u3057\u305f\u3002<\/p>\n<p>\u6700\u8fd1\u3001\u30de\u30af\u30ed\u30d5\u30a1\u30fc\u30b8\u306e\u708e\u75c7\u53cd\u5fdc\u306b\u304a\u3051\u308b\u30cd\u30ac\u30c6\u30a3\u30d6\u30d5\u30a3\u30fc\u30c9\u30d0\u30c3\u30af\u6a5f\u69cb\u3068\u3057\u3066\u306e\u300c\u8d85\u786b\u9ec4\u5206\u5b50\u300d\u306e\u5f79\u5272\u304c\u6771\u5317\u5927\u5b66\u304b\u3089\u5831\u544a (\u5f53\u6559\u5ba4\u306e\u5352\u696d\u751f \u6b66\u7530\u304c\u53c2\u52a0\u3001Takeda et.al., <em>Redox Biol.<\/em> 2023) \u3055\u308c\u307e\u3057\u305f\u304c\u3001\u30df\u30af\u30ed\u30b0\u30ea\u30a2\u306b\u304a\u3044\u3066\u3082\u540c\u69d8\u306e\u6a5f\u69cb\u304c\u5b58\u5728\u3059\u308b\u306e\u304b\u5426\u304b\u3001\u6297\u708e\u75c7\u5264\u306e\u4f5c\u7528\u6a5f\u5e8f\u3068\u306e\u95a2\u9023\u306f\u3069\u306e\u3088\u3046\u3067\u3042\u308b\u304b\u3001\u8ffd\u53ca\u3057\u3066\u3044\u307e\u3059\u3002<\/p>\n<p><img loading=\"lazy\" decoding=\"async\" class=\"alignnone  wp-image-332\" src=\"https:\/\/www.m.ehime-u.ac.jp\/school\/mcp\/wp-content\/uploads\/2026\/01\/\u77e2\u91ce\u5148\u751f.png\" alt=\"\" width=\"340\" height=\"338\" srcset=\"https:\/\/www.m.ehime-u.ac.jp\/school\/mcp\/wp-content\/uploads\/2026\/01\/\u77e2\u91ce\u5148\u751f.png 283w, https:\/\/www.m.ehime-u.ac.jp\/school\/mcp\/wp-content\/uploads\/2026\/01\/\u77e2\u91ce\u5148\u751f-150x150.png 150w\" sizes=\"auto, (max-width: 340px) 100vw, 340px\" \/><\/p>\n<ol start=\"4\">\n<li>\u8133\u816b\u760d\u306e\u65b0\u898f\u8a3a\u65ad\u30fb\u6cbb\u7642\u306e\u958b\u767a\u306b\u5411\u3051\u3066<\/li>\n<\/ol>\n<p>\u4e00\u53e3\u306b\u8133\u816b\u760d\u3068\u8a00\u3063\u3066\u3082\u69d8\u3005\u306a\u75c5\u578b\u304c\u3042\u308a\u3001\u6cbb\u7642\u6cd5\u304c\u5927\u304d\u304f\u7570\u306a\u308b\u3053\u3068\u304c\u3042\u308a\u307e\u3059\u3002\u305d\u306e\u305f\u3081\u6cbb\u7642\u306b\u5148\u7acb\u3063\u3066\u75c5\u578b\u304c\u8a73\u7d30\u306b\u308f\u304b\u308b\u3053\u3068\u306b\u5927\u304d\u306a\u610f\u5473\u304c\u3042\u308a\u307e\u3059\u3002\u8fd1\u5e74\u3067\u306f\u907a\u4f1d\u5b50\u5909\u7570\u306b\u57fa\u3065\u304f\u75c5\u578b\u306e\u5206\u985e\u6307\u6a19\u304c\u78ba\u7acb\u3057\u3066\u304a\u308a\u3001\u305d\u308c\u306b\u6cbf\u3048\u3070\u8a3a\u65ad\u306f\u78ba\u5b9a\u3067\u304d\u307e\u3059\u3002\u3057\u304b\u3057\u306a\u304c\u3089\u8133\u306f\u982d\u84cb\u9aa8\u306e\u4e2d\u306b\u683c\u7d0d\u3055\u308c\u3066\u3044\u3066\u3001\u5916\u79d1\u7684\u306a\u30a2\u30af\u30bb\u30b9\u306b\u304a\u3044\u3066\u4ed6\u306e\u81d3\u5668\u306b\u306a\u3044\u969c\u58c1\u304c\u3042\u308a\u307e\u3059\u3002\u753b\u50cf\u8a3a\u65ad\u6280\u8853\u306e\u9032\u5c55\u306f\u3053\u3046\u3057\u305f\u554f\u984c\u306b\u5927\u304d\u304f\u8ca2\u732e\u3057\u3066\u304d\u307e\u3057\u305f\u304c\u3001\u305d\u308c\u3067\u3082\u3044\u307e\u3060\u306b\u539f\u5247\u3068\u3057\u3066\u75c5\u578b\u306e\u78ba\u5b9a\u306f\u751f\u691c\u306b\u3088\u3063\u3066\u3044\u307e\u3059\u3002\u305b\u3081\u3066\u8853\u4e2d\u306b\u8fc5\u901f\u306b\u75c5\u578b\u304c\u78ba\u5b9a\u3067\u304d\u305f\u308a\u3001\u8853\u524d\u306b\u907a\u4f1d\u5b50\u5909\u7570\u304c\u691c\u51fa\u3067\u304d\u308c\u3070\u3001\u751f\u691c\u3084\u6cbb\u7642\u306e\u4f4d\u7f6e\u3065\u3051\u304c\u5909\u308f\u3063\u3066\u6765\u308b\u3053\u3068\u304c\u671f\u5f85\u3055\u308c\u307e\u3059\u3002\u73fe\u5728\u308f\u308c\u308f\u308c\u306f\u8133\u795e\u7d4c\u5916\u79d1\u3068\u306e\u5171\u540c\u7814\u7a76\u306b\u3088\u308a\u3001\u751f\u691c\u8a66\u6599\u3084\u8133\u810a\u9ac4\u6db2\u4e2d\u304b\u3089\u306e\u907a\u4f1d\u5b50\u5909\u7570\u691c\u51fa\u6280\u8853\u306e\u958b\u767a\u3092\u884c\u3063\u3066\u3044\u307e\u3059\u3002<\/p>\n<p>\u307e\u305f\u304c\u3093\u6cbb\u7642\u3068\u3044\u3046\u89b3\u70b9\u3067\u306f\u3001\u8033\u9f3b\u54bd\u5589\u79d1\u30fb\u982d\u9838\u90e8\u5916\u79d1\u3068\u306e\u5171\u540c\u306b\u3088\u308a\u3001\u982d\u9838\u90e8\u6241\u5e73\u4e0a\u76ae\u304c\u3093\u306e\u30ea\u30f3\u30d1\u7bc0\u8ee2\u79fb\u3092\u6291\u6b62\u3059\u308b\u3053\u3068\u3092\u76ee\u6307\u3057\u305f\u3001\u6cbb\u7642\u6a19\u7684\u5206\u5b50\u306e\u63a2\u7d22\u3082\u884c\u3063\u3066\u304d\u307e\u3057\u305f\u3002\u73fe\u5728\u306f\u816b\u760d\u7d30\u80de\u304c\u767a\u73fe\u3059\u308b\u3053\u308c\u3089\u306e\u56e0\u5b50\u3092\u6291\u5236\u3059\u308b\u3053\u3068\u3067\u5f97\u3089\u308c\u305f\u5bbf\u4e3b\u514d\u75ab\u3068\u306e\u95a2\u4fc2\u6027\u306e\u5909\u5316\u306b\u3064\u3044\u3066\u8ffd\u53ca\u3057\u3066\u3044\u307e\u3059\u3002<\/p>\n","protected":false},"excerpt":{"rendered":"<p>\u300c\u751f\u4f53\u96fb\u6c17\u300d\u3092\u518d\u5b9a\u7fa9\u3059\u308b\uff0d\u96fb\u6c17\u4fe1\u53f7\u304c\u3082\u3064\u65b0\u305f\u306a\u5f79\u5272\u3078\u306e\u6311\u6226 (\u4e3b\u306b\u6cb3\u5408) \u8133\u6ce2\u3084\u5fc3\u96fb\u56f3\u304b\u3089\u3082\u5206\u304b\u308b\u3088\u3046\u306b\u3001\u79c1\u305f\u3061\u306e\u8eab\u4f53\u306f\u81f3\u308b\u3068\u3053\u308d\u3067\u5fae\u5f31\u306a\u300c\u96fb\u6c17\u4fe1\u53f7\u300d\u3092\u751f\u6210\u3057\u3001\u751f\u547d\u6d3b\u52d5\u3092\u7dad\u6301\u3057\u3066\u3044\u307e\u3059\u3002\u3053\u306e\u96fb\u6c17\u306e\u751f\u6210\u3068\u611f\u77e5\u6a5f\u69cb\u306f\u3001\u9577\u3089\u304f [&hellip;]<\/p>\n","protected":false},"author":1,"featured_media":0,"parent":11,"menu_order":2,"comment_status":"closed","ping_status":"closed","template":"","meta":{"footnotes":""},"class_list":["post-39","page","type-page","status-publish","hentry"],"_links":{"self":[{"href":"https:\/\/www.m.ehime-u.ac.jp\/school\/mcp\/index.php?rest_route=\/wp\/v2\/pages\/39","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/www.m.ehime-u.ac.jp\/school\/mcp\/index.php?rest_route=\/wp\/v2\/pages"}],"about":[{"href":"https:\/\/www.m.ehime-u.ac.jp\/school\/mcp\/index.php?rest_route=\/wp\/v2\/types\/page"}],"author":[{"embeddable":true,"href":"https:\/\/www.m.ehime-u.ac.jp\/school\/mcp\/index.php?rest_route=\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/www.m.ehime-u.ac.jp\/school\/mcp\/index.php?rest_route=%2Fwp%2Fv2%2Fcomments&post=39"}],"version-history":[{"count":20,"href":"https:\/\/www.m.ehime-u.ac.jp\/school\/mcp\/index.php?rest_route=\/wp\/v2\/pages\/39\/revisions"}],"predecessor-version":[{"id":333,"href":"https:\/\/www.m.ehime-u.ac.jp\/school\/mcp\/index.php?rest_route=\/wp\/v2\/pages\/39\/revisions\/333"}],"up":[{"embeddable":true,"href":"https:\/\/www.m.ehime-u.ac.jp\/school\/mcp\/index.php?rest_route=\/wp\/v2\/pages\/11"}],"wp:attachment":[{"href":"https:\/\/www.m.ehime-u.ac.jp\/school\/mcp\/index.php?rest_route=%2Fwp%2Fv2%2Fmedia&parent=39"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}