Principal Investigator

Ryuta Watanabe, MD, PhD
Senior Assistant Professor
Department of Urology, Ehime University Graduate School of Medicine
Research Interests
Prostate cancer progression and treatment resistance, neuroendocrine prostate cancer, lineage plasticity, single-cell analysis, and spatial transcriptomics
Career
- 2008 — MD, Ehime University School of Medicine
- 2020 — PhD, Ehime University Graduate School of Medicine
- 2020–2021 — Postdoctoral Research Fellow, Peter S. Nelson Laboratory, Fred Hutchinson Cancer Center, Seattle, USA
- 2021 — Assistant Professor, Department of Urology, Ehime University Hospital
- 2023 — Postdoctoral Research Fellow, Fred Hutchinson Cancer Center, Seattle, USA
- 2024 — Assistant Professor, Department of Urology, Ehime University Hospital
- 2025–present — Senior Assistant Professor, Department of Urology, Ehime University Graduate School of Medicine
Core Members

Takashi Saika, MD, PhD
Professor
Department of Urology, Ehime University Graduate School of Medicine
Research Interests
Urologic oncology, prostate cancer, and urologic surgery
Career
- 1988 — MD, Okayama University Medical School
- 1992 — PhD, Okayama University Graduate School
- 2000 — Research Fellow, Department of Urology, Baylor College of Medicine, USA
- 2010 — Associate Professor, Department of Urology, Okayama University Graduate School of Medicine, Dentistry and Pharmaceutical Sciences
- 2011 — Director, Department of Urology, Hiroshima City Hiroshima Citizens Hospital
- 2016 — Professor, Department of Urology, Ehime University Graduate School of Medicine
- 2019 — Vice Dean, Ehime University Graduate School of Medicine
- 2023 — Vice Director, Ehime University Hospital

Noriyoshi Miura, MD, PhD
Associate Professor
Department of Urology, Ehime University Graduate School of Medicine
Research Interests
Urologic oncology, prostate cancer, renal cell carcinoma, cancer pharmacotherapy, robotic surgery, and laparoscopic surgery
Career
- 2001 — MD, Ehime University School of Medicine
- Engaged in clinical practice and research at the Department of Urology, Ehime University Hospital, and affiliated institutions
- Present — Associate Professor, Department of Urology, Ehime University Graduate School of Medicine
Graduate Students

Akina Arai
Prostate cancer: functional characterization of OPN3, AR-V7, and basal-associated phenotype

Keigo Nishida
Image-guided technologies: support for percutaneous renal access, AI-based image analysis, and surgical support technologies

Naoya Sugihara
Computational biomedicine: mathematical modeling, hydronephrosis models, renal pelvis pressure analysis, and CFD applications

Tsuyoshi Ohno
Research theme under development

Ryo Shiode
Research theme under development
学部学生

Keito Kagimoto
(6th-year medical student)

Rena Kutsuwa
(2nd-year medical student)
Collaborators at Ehime University
Domestic Collaborators
Yuichiro Sawada
Tadahiko Kikugawa