2020

Yagi Y, Kuwahara M, Suzuki J, Imai Y, Yamashita M: Glycolysis and subsequent mevalonate biosynthesis play an important role in Th2 cell differentiation. Biochem.Biophys.Res.Commun. (2020) 530 (2): 355-361 https://doi.org/10.1016/j.bbrc.2020.08.009

Toriyama K, Kuwahara M, Kondoh H, Mikawa T, Takemori N, Konishi A, Yorozuya T, Yamada T, Soga T, Shiraishi A, Yamashita M: T cell-specific deletion of Pgam1 reveals a critical role for glycolysis in T cell responses. Commun. Biol. (2020) 3 (394) https://doi.org/10.1038/s42003-020-01122-w

Takemori A, Butcher DS, Harman VM, Brownridge PJ, Shima K, Higo D, Ishizaki J, Hasegawa H, Suzuki J, Yamashita M, Loo JA, Ogorzalek Loo RR, Beynon RJ, Anderson LC, Takemori N: PEPPI-MS: polyacrylamide gel-based prefractionation for analysis of intact proteoforms and protein complexes by mass spectrometry.

J. Proteo. Res. (2020) 19 (9): 3593-3876 https://pubs.acs.org/doi/10.1021/acs.jproteome.0c00303

Omori-Miyake M, Watarai H, Sato K, Ziegler SF, Yagi J:  An accumulation of two populations of dendritic cells in skin-draining lymph nodes in response to the expression of thymic stromal lymphopoietin in the skin. Cell Immunol. (2020) 353: 104116 https://doi.org/10.1016/j.cellimm.2020.104116

2019

Nomura S, Takahashi H, Suzuki J, Kuwahara M, Yamashita M, Sawasaki T: Pyrrothiogatain acts as an inhibitor of GATA family proteins and inhibits Th2 cell differentiation in vitro. Sci. Rep. (2019) 9: 17335 https://doi.org/10.1038/s41598-019-53856-1

Fu Y, Koh B, Kuwahara M, Ulrich BJ, Kharwadkar R, Yamashita M, Kaplan MH: BATF-Interacting Proteins Dictate Specificity in Th Subset Activity. J. Immunol. (2019) 203 (7): 1989-1998 https://doi.org/10.4049/jimmunol.1900128

Onuma H, Kawamura R, Tabara Y, Yamashita M, Ohashi J, Kawasaki E, Imagawa A, Yamada Y, Chujo D, Takahashi K, Suehiro T, Takata Y, Osawa H, Makino H: Variants in the BACH2 and CLEC16A gene may be associated with susceptibility to insulin-triggered type 1 diabetes. J. Diabetes Investig. (2019) 10 (6): 1447-1453 https://doi.org/10.1111/jdi.13057

Yamada T, Nabe S, Toriyama K, Suzuki J, Inoue K, Imai Y, Shiraishi A, Takenaka K, Yasukawa M, Yamashita M: Histone H3K27 Demethylase Negatively Controls the Memory Formation of Antigen-Stimulated CD8+ T Cells. J. Immunol. (2019) 202 (4): 1088-1098 https://doi.org/10.4049/jimmunol.1801083

2018

Nabe S, Yamada T, Suzuki J, Toriyama K, Yasuoka T, Kuwahara M, Shiraishi A, Takenaka K, Yasukawa M, Yamashita M: Reinforce the antitumor activity of CD8+ T cells via glutamine restriction. Cancer Sci. (2018) 109 (12): 3737-3750 https://doi.org/10.1111/cas.13827

Suzuki J, Yamada T, Inoue K, Nabe S, Kuwahara M, Takemori N, Takemori A, Matsuda S, Kanoh M, Imai Y, Yasukawa M, Yamashita M: The tumor suppressor menin prevents effector CD8 T-cell dysfunction by targeting mTORC1-dependent metabolic activation. Nat. Commun. (2018) 9 (1): 3296 https://doi.org/10.1038/s41467-018-05854-6

Yamashita M, Kuwahara M: The critical role of Bach2 in regulating type-2 chronic airway inflammation. Int. Immunol. (2018) 30 (9): 397-402 https://doi.org/10.1093/intimm/dxy020

2017

Matsui-Hasumi A, Sato Y, Uto-Konomi A, Yamashita S, Uehori J, Yoshimura A, Yamashita M, Asahara H, Suzuki S, Kubo M： E3 ubiquitin ligases SIAH1/2 regulate hypoxia-inducible factor-1 (HIF-1)-mediated Th17 cell differentiation. Int. Immunol. (2017) 29 (3): 133-143 https://doi.org/10.1093/intimm/dxx014

Ebina-Shibuya R, Matsumoto M, Kuwahara M, Jang KJ, Sugai M, Ito Y, Funayama R, Nakayama K, Sato Y, Ishii N, Okamura Y, Kinoshita K, Kometani K, Kurosaki T, Muto A, Ichinose M, Yamashita M, Igarashi K： Inflammatory responses induce an identity crisis of alveolar macrophages, leading to pulmonary alveolar proteinosis. J. Biol. Chem. (2017) 292 (44): 18098-18112 https://doi.org/10.1074/jbc.M117.808535

2016

Yamada T, Kanoh M, Nabe S, Yasuoka T, Suzuki J, Matsumoto A, Kuwahara M, Maruyama S, Fujimoto T, Sakisuka R, Yasukawa M, Yamashita M: Menin Plays a Critical Role in the Regulation of the Antigen-Specific CD8+ T Cell Response upon Listeria Infection. J. Immunol. (2016) 197 (10): 4079-4089 https://doi.org/10.4049/jimmunol.1502295

Kuwahara M, Ise W, Ochi M, Suzuki J, Kometani K, Maruyama S, Izumoto M, Matsumoto A, Takemori N, Takemori A, Shinoda K, Nakayama T, Ohara O, Yasukawa M, Sawasaki T, Kurosaki T, Yamashita M: Bach2-Batf interactions control Th2-type immune response by regulating the IL-4 amplification loop. Nat. Commun.  (2016) 7: 12596 https://doi.org/10.1038/ncomms12596

Yasuoka T, Kuwahara M, Yamada T, Maruyama S, Suzuki J, Taniguchi M, Yasukawa M and Yamashita M: The transcriptional repressor Gfi1 plays a critical role in the development of NKT1- and NKT2-type iNKT cells. PLoS ONE (2016) 11 (6): e0157395 https://doi.org/10.1371/journal.pone.0157395

Yagi S, Abe M, Yamashita M, Mori K, Yamanishi H, Arimitsu E, Yamamoto Y, Takeshita E, Ikeda Y and Hiasa Y: Carbonic anhydrate I epitope peptide improves inflammation in a murine model of inflammatory bowel disease. Inflamm. Bowel. Dis. (2016) 22 (8): 1835-1846 https://doi.org/10.1097/MIB.0000000000000781

Suzuki J, Maruyama S, Tamauchi H, Kuwahara M, Horiuchi M, Mizuki M, Ochi M, Sawasaki T, Zhu J, Yasukawa M, Yamashita M: Gfi1, a transcriptional repressor, inhibits the induction of the T helper type1 programme in activated CD4 T cells. Immunology (2016) 147 (4): 476-487 https://doi.org/10.1111/imm.12580