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Department of Biochemistry and Molecular Genetics

Introduction

Molecule and Funtion
Department of Biochemistry and Molecular Genetics

【Contact】
Molecule and Funtion
Department of Biochemistry and Molecular Genetics
TEL (+81)-89-960-5254 FAX (+81)-89-960-5256

Result

  • SPOP is essential for DNA-protein crosslink repair in prostate cancer cells: SPOP-dependent removal of topoisomerase 2A from the topoisomerase 2A-DNA cleavage complex.
    Watanabe R, Maekawa M, Hieda M, Taguchi T, Miura N, Kikugawa T, Saika T, Higashiyama S.
    Mol. Biol. Cell. 31 (6): 478-490. 2020.
  • Cullin-3/KCTD10 complex is essential for K27-polyubiquitination of EIF3D in human hepatocellular carcinoma HepG2 cells.
    Maekawa M, Hiyoshi H, Nakayama J, Kido K, Sawasaki T, Semba K, Kubota E, Joh T, Higashiyama S.
    Biochem. Biophys. Res. Commun. 516 (4): 1116-1122. 2019.
  • SNX9 determines the surface levels of integrin β1 in vascular endothelial cells: Implication in poor prognosis of human colorectal cancers overexpressing SNX9.
    Tanigawa K, Maekawa M, Kiyoi T, Nakayama J, Kitazawa R, Kitazawa S, Semba K, Taguchi T, Akita S, Yoshida M, Ishimaru K, Watanabe Y, Higashiyama S.
    J Cell Physiol. 234: 17280-17294. 2019.

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