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Department of Gastroenterology and Metabology

Introduction

Pathogenesis and Pathophysiology
Department of Gastroenterology and Metabology

【Contact】
Pathogenesis and Pathophysiology
Department of Gastroenterology and Metabology
Shitsukawa, Toon, Ehime 791-0295, Japan
TEL (+81)-89-960-5308　FAX (+81)-89-960-5310

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Research content

Our motto is providing the highest levels of treatment and management to patients with all disciplines of internal medicine, especially of gastroenterology and metabology. The strategies for our researches are (1) clinical experiments to develop insights about disease pathogenesis, (2) basic studies in animal models and experimental systems when it becomes difficult to perform study in human, and (3) evaluate new therapeutic concepts.

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Result

  • Real-time tissue elastography for evaluation of hepatic fibrosis and portal hypertension in non-alcoholic fatty liver diseases.
    Ochi H, Hirooka M, Koizumi Y, Miyake E, Tokumoto Y, Soga Y, Tada F, Abe M, Hiasa Y, Onji M.
    Hepatology. 2012 Apr 5. doi: 10.1002/hep.25756. [Epub ahead of print]
  • Ribavirin regulates hepatitis C virus replication through enhancing interferon-stimulated genes and interleukin 8.
    Tokumoto Y, Hiasa Y, Uesugi K, Watanabe T, Mashiba T, Abe M, Kumagi T, Ikeda Y, Matsuura B, Onji M.
    J Infect Dis. 2012 Apr;205(7):1121-30. Epub 2012 Feb 21.
  • Regulatory dendritic cells pulsed with carbonic anhydrase I protect mice from colitis induced by CD4(+)CD25(-) T cells.
    Yamanishi H, Murakami H, Ikeda Y, Abe M, Kumagi T, Hiasa Y, Matsuura B, Onji M.
    J Immunol. 2012 Mar 1;188(5):2164-72. Epub 2012 Jan 30.
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