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Department of Neurology and Clinical Pharmacology

Introduction

Pathogenesis and Pathophysiology
Department of Neurology and Clinical Pharmacology

【Contact】
Pathogenesis and Pathophysiology
Department of Neurology and Clinical Pharmacology
Shitsukawa, Toon, Ehime 791-0295, Japan
TEL (+81)-89-960-5095 FAX (+81)-89-960-5938

Research content

Drugs are among the most important modulators of therapeutic success. The large amount of knowledge needed to select, prescribe, and administer medication correctly and safely requires new, continuous, and multidisciplinary strategies to assure quality in daily practice. The Department of Therapeutic Medicine (Clinical Pharmacology and Neurology) promotes personalised medicine in the field of drug therapy with a major focus on the challenges of the development of new drugs, combination therapy (drug interactions) and renal impairment.

Result

  • Masahiro Nomoto, Masahiro Nagai, Noriko Nishikawa, Rina Ando, Yoshifumi Kagamiishi, Koji Yano, Shigeto Saito, Atsushi Takeda.
    Pharmacokinetics and safety/efficacy of levodopa pro-drug ONO-2160/carbidopa for Parkinson’s disease.
    eNeurologicalSci 13(2018):8-13
  • Rina Ando, Mohammed Emamussalehin Choudhury, Yuki Yamanishi, Win Thiri Kyaw, Madoka Kubo, Mariko Kannou, Noriko Nishikawa, Junya Tanaka, Masahiro Nomoto, Masahiro Nagai.
    Modafinil alleviates levodopa-induced excessive nighttime sleepiness and restores monoaminergic systems in a nocturnal animal model of Parkinson’s disease.
    J Pharmacol Sci. 136(2018):266-271.
  • Rina Ando, Hirotaka Iwaki, Tomoaki Tsujii, Masahiro Nagai, Noriko Nishikawa, Hayato Yabe, Ikuko Aiba, Kazuko Hasegawa, Yoshio Tsuboi, Masashi Aoki, Kenji Nakashima and Masahiro Nomoto; Parkinson’s Disease Safe Driving Study Group of Japan.
    The Clinical Findings Useful for Driving Safety Advice for Parkinson’s Disease Patients.
    Intern Med. 2018 Feb 28. doi: 10.2169/internalmedicine.9653-17.

Staff

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