2025

Miyuki Omori-Miyake, Ryosuke Kawakami, Makoto Kuwahara, Masataka Okabe, Jun Muto, Takeshi Imamura, Masakatsu Yamashita: Loss of Bach2 in T cells causes prolonged allergic inflammation through accumulation of effector T cells and disruption of epidermal barrier. Journal of Allergy and Clinical Immunology (2025) in press. https://doi.org/10.1016/j.jaci.2025.01.036

2024

Yuichiro Ukon, Takashi Kaito, Hiromasa Hirai, Takayuki Kitahara, Masayuki Bun, Joe Kodama, Daisuke Tateiwa, Shinichi Nakagawa, Masato Ikuta, Takuya Furuichi, Yuya Kanie, Takahito Fujimori, Shota Takenaka, Tadashi Yamamuro, Satoru Otsuru, Seiji Okada, Masakatsu Yamashita, Takeshi Imamura: Cellular senescence by loss of Men1 in osteoblasts is critical for age-related osteoporosis.Aging Cell(2024) 00:e14254. https://doi.org/10.1111/acel.14254

Waichi Yamamoto, Taisuke Hamada, Junpei Suzuki, Yuko Matsuoka,
Miyuki Omori‐Miyake, Makoto Kuwahara, Akira Matsumoto, Shunsuke Nomura, Amane Konishi, Toshihiro Yorozuya, Masakatsu Yamashita: Suppressive effect of the anesthetic propofol on the T cell function and T cell‐dependent immune responses. Scientific reports(2024) 14:19337. https://doi.org/10.1038/s41598-024-69987-z

2023

Kakuda T, Suzuki J, Matsuoka Y, Kikugawa T, Saika T, Yamashita M: Senescent CD8+ T cells acquire NK cell-like innate functions to promote antitumor immunity. Cancer Sci.(2023) 114 (7): 2810-2820 https://doi.org/10.1111/cas.15824

Noda H, Suzuki J, Matsuoka Y, Matsumoto A, Kuwahara M, Kamei Y, Takada Y, Yamashita M: The histone demethylase Utx controls CD8+ T-cell-dependent antitumor immunity via epigenetic regulation of the effector function. Cancer Sci.(2023) 114 (7): 2787-2797 https://doi.org/10.1111/cas.15814

Okamoto M*, Omori-Miyake M*, Kuwahara M, Okabe M, Eguchi M, Yamashita M: The inhibition of glycolysis in T cells by a Jak inhibitor ameliorates the pathogenesis of allergic contact dermatitis in mice. J. Invest. Dermatol.(2023) 143 (10): 1972-1982.e5 https://doi.org/10.1016/j.jid.2023.03.1667

Ikeda N, Kubota H,Suzuki R, Morita M, Yoshimura A, Osada Y, Kishida K, Kitamura D, Iwata A, Yotsumoto S, Kurotaki D, Nishimura K, Nishiyama A, Tamura T, Kamatani T, Tsunoda T, Miyako M, Asahina Y,Hayashi Y,Harada H, Harada Y, Yokota A, Hirai H, Seki T, Kuwahara M, Yamashita M, Shichino S, Tanaka M, Asano K: The early neutrophil-committed progenitors aberrantly differentiate into immunoregulatory monocytes during emergency myelopoiesis. Cell Rep. (2023) 42 (3): 112165 https://doi.org/10.1016/j.celrep.2023.112165

Taniguchi Y, Suemori K, Tanaka K, Okamoto A, Murakami A, Miyamoto H, Takasuka Y, Yamashita M, Takenaka K: Long-term transition of antibody titers in healthcare workers following the first to fourth doses of mRNA COVID-19 vaccine: Comparison of two automated SARS-CoV-2 immunoassays. J. Infect. Chemother.  (2023) 29 (5): 534-538 https://doi.org/10.1016/j.jiac.2023.01.007

2022

Suemori K , Taniguchi  Y, Okamoto A , Murakami A , Ochi F , Aono H , Hato N, Osawa H, Miyamoto H, Sugiyama T ,Yamashita M, Tauchi H, Takenaka K: Two-Year Seroprevalence Surveys of SARS-CoV-2 Antibodies among Outpatients and Healthcare Workers in Ehime, Japan. Jpn. J. Infect. Dis.  (2022) 75 (5): 523-526 https://doi.org/10.7883/yoken.JJID.2022.155

Choudhury ME, Mikami K, Nakanishi Y, Matsuura T, Utsunomiya R, Yano H, Kubo M, Ando R, Iwanami J, Yamashita M, Nagai M, Tanaka J: Insomnia and depressive behavior of MyD88-deficient mice: Relationships with altered microglial functions. J. Neuroimmunol. (2022) 363: 577794 https://doi.org/10.1016/j.jneuroim.2021.577794

Konishi A, Suzuki J, Kuwahara M, Matsumoto A, Nomura S, Soga T, Yorozuya T,Yamashita M: Glucocorticoid imprints a low glucose metabolism onto CD8 T cells and induces the persistent suppression of the immune response. Biochem. Biophys. Res. Commun. (2022) 588: 34-40 https://doi.org/10.1016/j.bbrc.2021.12.050

2021

Inoue T*, Omori-Miyake M*, Maruyama S, Okabe M, Kuwahara M, Honda H, Miura H, Yamashita M: The Loss of H3K27 Histone Demethylase Utx in T Cells Aggravates Allergic Contact Dermatiti. J. Immunol. (2021) 207 (9): 2223–2234 https://doi.org/10.4049/jimmunol.2001160

Tohyama M, Matsumoto A, Tsuda T, Dai X, Shiraishi K, Sayama K: Suppression of IL-17A-induced CCL20 production by cytokine inducible SH2-containing protein 1 in epidermal keratinocytes. J. Dermatol. Sci.(2021) 101 (3): 202-209 https://doi.org/10.1016/j.jdermsci.2021.01.005