2016

Yamada T, Kanoh M, Nabe S, Yasuoka T, Suzuki J, Matsumoto A, Kuwahara M, Maruyama S, Fujimoto T, Sakisuka R, Yasukawa M, Yamashita M: Menin Plays a Critical Role in the Regulation of the Antigen-Specific CD8+ T Cell Response upon Listeria Infection. J. Immunol. (2016) 197 (10): 4079-4089 https://doi.org/10.4049/jimmunol.1502295

Kuwahara M, Ise W, Ochi M, Suzuki J, Kometani K, Maruyama S, Izumoto M, Matsumoto A, Takemori N, Takemori A, Shinoda K, Nakayama T, Ohara O, Yasukawa M, Sawasaki T, Kurosaki T, Yamashita M: Bach2-Batf interactions control Th2-type immune response by regulating the IL-4 amplification loop. Nat. Commun.  (2016) 7: 12596 https://doi.org/10.1038/ncomms12596

Yasuoka T, Kuwahara M, Yamada T, Maruyama S, Suzuki J, Taniguchi M, Yasukawa M and Yamashita M: The transcriptional repressor Gfi1 plays a critical role in the development of NKT1- and NKT2-type iNKT cells. PLoS ONE (2016) 11 (6): e0157395 https://doi.org/10.1371/journal.pone.0157395

Yagi S, Abe M, Yamashita M, Mori K, Yamanishi H, Arimitsu E, Yamamoto Y, Takeshita E, Ikeda Y and Hiasa Y: Carbonic anhydrate I epitope peptide improves inflammation in a murine model of inflammatory bowel disease. Inflamm. Bowel. Dis. (2016) 22 (8): 1835-1846 https://doi.org/10.1097/MIB.0000000000000781

Suzuki J, Maruyama S, Tamauchi H, Kuwahara M, Horiuchi M, Mizuki M, Ochi M, Sawasaki T, Zhu J, Yasukawa M, Yamashita M: Gfi1, a transcriptional repressor, inhibits the induction of the T helper type1 programme in activated CD4 T cells. Immunology (2016) 147 (4): 476-487 https://doi.org/10.1111/imm.12580

2015

Nagy-Szakal D, Mir SA, Harris RA, Dowd SE, Yamada T, Lacorazza HD, Tatevian N, Smith CW, de Zoeten EF, Klein J, Kellermayer R: Loss of n-6 fatty acid induced pediatric obesity protects against acute murine colitis. FASEB J. (2015) 29 (8): 3151-3159 https://doi.org/10.1096/fj.14-267690

Lee PH, Yamada T, Park CS, Shen Y, Puppi M, Lacorazza HD: G0S2 modulates homeostatic proliferation of naïve CD8⁺ T cells and inhibits oxidative phosphorylation in mitochondria. Immunol. Cell Biol. (2015) 93 (7): 605-615 https://doi.org/10.1038/icb.2015.9

Kanoh M, Maruyama S, Shen H, Matsumoto A, Shinomiya H, Przybilla K, Gouin E, Cossart P, Goebel W, Asano Y: Listeria arpJ gene modifies T helper type 2 subset differentiation. J. Infect. Dis. (2015) 212 (2): 223-233 https://doi.org/10.1093/infdis/jiv021

Maruyama S, Kanoh M, Matsumoto A, Kuwahara M, Yamashita M and Asano Y: A novel function of Interferon regulatory factor-1: Inhibition of Th2 cells by down-regulating the Il4 gene during Listeria infection. Int. Immunol. (2015) 27 (3):143-152 https://doi.org/10.1093/intimm/dxu092

2014

Tanaka S, Suto A, Iwamoto T, Kashiwakuma D, Kagami SI, Suzuki K, Takatori H, Tamachi T, Hirose K, Onodera A, Suzuki J, Ohara O, Yamashita M, Nakayama T and Nakajima H: Sox5 and c-Maf cooperatively induce Th17 cell differentiation via RORgt induction as downstream targets of Stat3. J. Exp. Med. (2014) 211 (9): 1857–1874 https://doi.org/10.1084/jem.20130791

Yoshida Y, Hayashi Y, Suda M, Tateno K, Okada S, Moriya J, Yokoyama M, Nojima A, Yamashita M, Kobayashi Y, Shimizu I, Minamino T: Notch Signaling Regulates the Lifespan of Vascular Endothelial Cells via a p16-Dependent Pathway. PLoS One (2014) 9 (6)：e100359 https://doi.org/10.1371/journal.pone.0100359

Kuwahara M, Suzuki J, Tofukuji S, Yamada T, Kanoh M, Matsumoto A, Maruyama S, Kometani K, Kurosaki T, Ohara O, Nakayama T and Yamashita M: Menin-Bach2 axis is critical for regulating CD4 T-cell senescence and cytokine homeostasis. Nat. Commun. (2014) 5: 3555 https://doi.org/10.1038/ncomms4555

Omori-Miyake M, Yamashita M, Tunemi Y, Kawashima M and Yagi J: In vitro assessment of IL-4- or IL-13-mediated changes in the structural components of keratinocytes in mice and humans. J. Invest. Dermatol. (2014) 134: 1342-1350 https://doi.org/10.1038/jid.2013.503

Yamada T, Park CS, Shen Y, Rabin KR and Lacorazza HD: G0S2 inhibits the proliferation of K562 cells by interacting with nucleolin in the cytosol. Leukemia Res. (2014) 38: 210-217 https://doi.org/10.1016/j.leukres.2013.10.006

Kubota T, Shimojo N, Nonaka K, Yamashita M, Ohara O, Igoshi Y, Ozawa N, Nakano T, Morita Y, Inoue Y, Arima T, Chiba K, Nakamura Y, Ikegami S, Masuda K and Kohno Y: Prebiotic consumption in pregnant and lactating women increases IL-27 expression in human milk. British J. Nutrition (2014) 111: 625-632 https://doi.org/10.1017/S0007114513003036

2013

Nojima A, Yamashita M, Yoshida Y, Shimizu I, Ichimiya H, Kamimura N, Kobayashi Y, Ohta S, Ishii N and Minamino T: Haploinsufficiency of Akt1 prolongs the life span of mice.  PLoS ONE (2013) 8: e69178 https://doi.org/10.1371/journal.pone.0069178

Kanoh M, Maruyama S, and Asano Y: Listeria infection inhibits IgE production in regional lymph nodes by suppressing the chemotaxis of basophils to lymph nodes. Microbiology & Immunology (2013) 57 (12): 842-848 https://doi.org/10.1111/1348-0421.12101

Yamada T, Park CS, Lacorazza HD: Genetic control of quiescence in hematopoietic stem cells. Cell Cycle (2013) 12 (15): 2376-2383 https://doi.org/10.4161/cc.25416

Matsumoto A, Maruyama S, Takahashi S, Miyoshi Y, Kanoh M, Kuwahara M, Yamada T, Yamashita M and Asano Y: Autophagic control of Listeria determines the infection induced death of macrophages. J. Vaccine Immunotechnol. (2013) 1:1-6 https://www.avensonline.org/fulltextarticles/JVIT-2377-6668-01-0001.html

Suzuki J, Kuwahara M, Tofukuji S, Imamura M, Kato F, Nakayama T, Ohara O and Yamashita M: A novel small compound SH-2251 suppresses Th2 cell-dependent airway inflammation through selective modulation of chromatin status at the Il5 gene locus. Plos one (2013) 8 (4): e61785 https://doi.org/10.1371/journal.pone.0061785

2012

Kuwahara M, Yamashita M, Shinoda K, Tofukuji S, Onodera A, Shinnakasu R, Motohashi S, Hosokawa H, Tumes D, Iwamura C, Lefebvre V, and Nakayama T: The transcription factor Sox4 is a downstream target of signaling by the cytokine TGF-β and suppresses TH2 differentiation. Nat. Immunol. (2012) 13: 778-786 https://doi.org/10.1038/ni.2362

Watanabe M, Nakajima S, Ohnuki K, Ogawa S, Yamashita M, Nakayama T, Murakami Y, Tanabe K, and Abe R: AP-1 is involved in ICOS gene expression downstream of TCR/CD28 and cytokine receptor signaling. Eur. J. Immunol. (2012) 42: 1850-1862 https://doi.org/10.1002/eji.201141897

Tofukuji S, Kuwahara M, Suzuki J, Ohara O, Nakayama T, and Yamashita M: Identification of a new pathway for Th1 cell development induced by cooperative stimulation with IL-4 and TGFβ. J. Immunol. (2012) 188 (10): 4846–4857 https://doi.org/10.4049/jimmunol.1103799

Park CS, Lee P-H, Yamada T, Burns A, Puppi M, and Lacorazza H.D: Kruppel-like factor 4 (KLF4) promotes the survival of natural killer cells and maintains the number of conventional dendritic cells in the spleen. J. Leukocyte Biology (2012) 91 (5): 739-750 https://doi.org/10.1189/jlb.0811413

Yamada T, Park CS, Burns A, Nakada D, Lacorazza H.D: The cytosolic protein G0S2 maintains quiescence in hematopoietic stem cells. Plos One (2012) 7 (5): e38280  https://doi.org/10.1371/journal.pone.0038280