2015

Nagy-Szakal D, Mir SA, Harris RA, Dowd SE, Yamada T, Lacorazza HD, Tatevian N, Smith CW, de Zoeten EF, Klein J, Kellermayer R: Loss of n-6 fatty acid induced pediatric obesity protects against acute murine colitis. FASEB J. (2015) 29 (8): 3151-3159 https://doi.org/10.1096/fj.14-267690

Lee PH, Yamada T, Park CS, Shen Y, Puppi M, Lacorazza HD: G0S2 modulates homeostatic proliferation of naïve CD8⁺ T cells and inhibits oxidative phosphorylation in mitochondria. Immunol. Cell Biol. (2015) 93 (7): 605-615 https://doi.org/10.1038/icb.2015.9

Kanoh M, Maruyama S, Shen H, Matsumoto A, Shinomiya H, Przybilla K, Gouin E, Cossart P, Goebel W, Asano Y: Listeria arpJ gene modifies T helper type 2 subset differentiation. J. Infect. Dis. (2015) 212 (2): 223-233 https://doi.org/10.1093/infdis/jiv021

Maruyama S, Kanoh M, Matsumoto A, Kuwahara M, Yamashita M and Asano Y: A novel function of Interferon regulatory factor-1: Inhibition of Th2 cells by down-regulating the Il4 gene during Listeria infection. Int. Immunol. (2015) 27 (3):143-152 https://doi.org/10.1093/intimm/dxu092

2014

Tanaka S, Suto A, Iwamoto T, Kashiwakuma D, Kagami SI, Suzuki K, Takatori H, Tamachi T, Hirose K, Onodera A, Suzuki J, Ohara O, Yamashita M, Nakayama T and Nakajima H: Sox5 and c-Maf cooperatively induce Th17 cell differentiation via RORgt induction as downstream targets of Stat3. J. Exp. Med. (2014) 211 (9): 1857–1874 https://doi.org/10.1084/jem.20130791

Yoshida Y, Hayashi Y, Suda M, Tateno K, Okada S, Moriya J, Yokoyama M, Nojima A, Yamashita M, Kobayashi Y, Shimizu I, Minamino T: Notch Signaling Regulates the Lifespan of Vascular Endothelial Cells via a p16-Dependent Pathway. PLoS One (2014) 9 (6)：e100359 https://doi.org/10.1371/journal.pone.0100359

Kuwahara M, Suzuki J, Tofukuji S, Yamada T, Kanoh M, Matsumoto A, Maruyama S, Kometani K, Kurosaki T, Ohara O, Nakayama T and Yamashita M: Menin-Bach2 axis is critical for regulating CD4 T-cell senescence and cytokine homeostasis. Nat. Commun. (2014) 5: 3555 https://doi.org/10.1038/ncomms4555

Omori-Miyake M, Yamashita M, Tunemi Y, Kawashima M and Yagi J: In vitro assessment of IL-4- or IL-13-mediated changes in the structural components of keratinocytes in mice and humans. J. Invest. Dermatol. (2014) 134: 1342-1350 https://doi.org/10.1038/jid.2013.503

Yamada T, Park CS, Shen Y, Rabin KR and Lacorazza HD: G0S2 inhibits the proliferation of K562 cells by interacting with nucleolin in the cytosol. Leukemia Res. (2014) 38: 210-217 https://doi.org/10.1016/j.leukres.2013.10.006

Kubota T, Shimojo N, Nonaka K, Yamashita M, Ohara O, Igoshi Y, Ozawa N, Nakano T, Morita Y, Inoue Y, Arima T, Chiba K, Nakamura Y, Ikegami S, Masuda K and Kohno Y: Prebiotic consumption in pregnant and lactating women increases IL-27 expression in human milk. British J. Nutrition (2014) 111: 625-632 https://doi.org/10.1017/S0007114513003036

2013

Nojima A, Yamashita M, Yoshida Y, Shimizu I, Ichimiya H, Kamimura N, Kobayashi Y, Ohta S, Ishii N and Minamino T: Haploinsufficiency of Akt1 prolongs the life span of mice.  PLoS ONE (2013) 8: e69178 https://doi.org/10.1371/journal.pone.0069178

Kanoh M, Maruyama S, and Asano Y: Listeria infection inhibits IgE production in regional lymph nodes by suppressing the chemotaxis of basophils to lymph nodes. Microbiology & Immunology (2013) 57 (12): 842-848 https://doi.org/10.1111/1348-0421.12101

Yamada T, Park CS, Lacorazza HD: Genetic control of quiescence in hematopoietic stem cells. Cell Cycle (2013) 12 (15): 2376-2383 https://doi.org/10.4161/cc.25416

Matsumoto A, Maruyama S, Takahashi S, Miyoshi Y, Kanoh M, Kuwahara M, Yamada T, Yamashita M and Asano Y: Autophagic control of Listeria determines the infection induced death of macrophages. J. Vaccine Immunotechnol. (2013) 1:1-6 https://www.avensonline.org/fulltextarticles/JVIT-2377-6668-01-0001.html

Suzuki J, Kuwahara M, Tofukuji S, Imamura M, Kato F, Nakayama T, Ohara O and Yamashita M: A novel small compound SH-2251 suppresses Th2 cell-dependent airway inflammation through selective modulation of chromatin status at the Il5 gene locus. Plos one (2013) 8 (4): e61785 https://doi.org/10.1371/journal.pone.0061785

2012

Kuwahara M, Yamashita M, Shinoda K, Tofukuji S, Onodera A, Shinnakasu R, Motohashi S, Hosokawa H, Tumes D, Iwamura C, Lefebvre V, and Nakayama T: The transcription factor Sox4 is a downstream target of signaling by the cytokine TGF-β and suppresses TH2 differentiation. Nat. Immunol. (2012) 13: 778-786 https://doi.org/10.1038/ni.2362

Watanabe M, Nakajima S, Ohnuki K, Ogawa S, Yamashita M, Nakayama T, Murakami Y, Tanabe K, and Abe R: AP-1 is involved in ICOS gene expression downstream of TCR/CD28 and cytokine receptor signaling. Eur. J. Immunol. (2012) 42: 1850-1862 https://doi.org/10.1002/eji.201141897

Tofukuji S, Kuwahara M, Suzuki J, Ohara O, Nakayama T, and Yamashita M: Identification of a new pathway for Th1 cell development induced by cooperative stimulation with IL-4 and TGFβ. J. Immunol. (2012) 188 (10): 4846–4857 https://doi.org/10.4049/jimmunol.1103799

Park CS, Lee P-H, Yamada T, Burns A, Puppi M, and Lacorazza H.D: Kruppel-like factor 4 (KLF4) promotes the survival of natural killer cells and maintains the number of conventional dendritic cells in the spleen. J. Leukocyte Biology (2012) 91 (5): 739-750 https://doi.org/10.1189/jlb.0811413

Yamada T, Park CS, Burns A, Nakada D, Lacorazza H.D: The cytosolic protein G0S2 maintains quiescence in hematopoietic stem cells. Plos One (2012) 7 (5): e38280  https://doi.org/10.1371/journal.pone.0038280

2011

Endo Y, Iwamura C, Kuwahara M, Suzuki A, Sugaya K, Tumes J. D, Tokoyoda K, Hosokawa H, Yamashita M, and Nakayama T: Eomesodermin controls interleukin-5 production in memory T helper 2 cells through inhibition of activity of the transcription factor GATA3. Immunity (2011) 35: 733-745 https://doi.org/10.1016/j.immuni.2011.08.017

Kitajima M, Ito T, Tumes J. D, Endo Y, Onodera A, Hashimoto K, Motohashi S, Yamashita M, Nishimura T, Ziegler F. S, and Nakayama T: Memory type 2 helper T cells induce long-lasting anti-tumor immunity by activating natural killer cells. Cancer Res. (2011) 71: 4790-4798 https://doi.org/10.1158/0008-5472.CAN-10-1572

Hirasaki Y, Iwamura C, Yamashita M, Ito T, Kitajima M, Shinoda K, Namiki T, Terasawa K, and Nakayama T: Repressor of GATA negatively regulates murine contact hypersensitivity through the inhibition of type-2 allergic responses. Clin. Immunol. (2011) 139: 267-276 https://doi.org/10.1016/j.clim.2011.02.009