研究業績

Publications (since 2010)

  1. Nishihara T, Tanaka J, Sekiya K, Nishikawa Y, Abe N, Hamada T, Kitamura S, Ikemune K, Ochi S, Choudhury ME, Yano H, Yorozuya T. Chronic constriction injury of the sciatic nerve in rats causes different activation modes of microglia between the anterior and posterior horns of the spinal cord. Neurochem. Int. doi: 10.1016/j.neuint.2020.104672, 2020.

 

  1. Umakoshi K, Choudhury ME, Nishioka R, Matsumoto H, Abe N, Nishikawa Y, Kikuchi S, Takeba J, Yano H, Yorozuya T, Sato N, Aibiki, M, Tanaka J. B lymphocytopenia and Bregs in a Not-To-Die murine sepsis model. Biochem. Biophys. Res. Commun., 523, 202-207, doi: 10.1016/j.bbrc.2019.12.041, 2020.

 

  1. Taguchi S, Choudhury ME, Miyanishi K, Nakanishi Y, Kameda K, Abe N, Yano H, Yorozuya T, Tanaka J. Aggravating effects of treadmill exercises during the early-onset period in a rat traumatic brain injury model: When should rehabilitation exercises be initiated? IBRO Rep. 7, 82-89, doi: 10.1016/j.ibror.2019.10.002, 2019.

 

  1. Choudhury ME, Miyanishi K, Takeda H, Islam A, Matsuoka N, Kubo M, Matsumoto S, Kunieda T, Nomoto M, Yano H, Tanaka J. Phagocytic elimination of synapses by microglia during sleep. Glia. doi: 10.1002/glia.23698. 2019.

 

  1. Sanada T, Islam A, Kaminota T, Kirino Y, Tanimoto R, Yoshimitsu H, Yano H, Mizuno Y, Okada M, Mitani S, Ugumori T, Tanaka J, Hato N. Elevated exosomal lysyl oxidase like 2 is a potential biomarker for head and neck squamous cell carcinoma. Laryngoscope. doi: 10.1002/lary.28142. 2019.

 

  1. Miyanishi K, Choudhury ME, Watanabe M, Kubo M, Nomoto M, Yano H, Tanaka J. Behavioral tests predicting striatal dopamine level in a rat hemi-Parkinson’s disease model. Neurochem. Int. 122, 38-46, 2019.

 

  1. Ueno Y, Ozaki S, Umakoshi A, Yano H, Choudhury ME, Abe N, Sumida Y, Kuwabara J, Uchida R, Islam A, Ogawa K, Ishimaru K, Yorozuya T, Kunieda T, Watanabe Y, Takada Y, Tanaka J. Chloride intracellular channel protein 2 in cancer and non-cancer human tissues: relationship with tight junctions. Tissue Barriers. https://doi.org/10.1080/21688370.2019.1593775 RESEARCH, 2019.

 

  1. Abe N, Choudhury ME, Watanabe M, Kawasaki S, Nishihara T, Yano H, Matsumoto S, Kunieda T, Kumon Y, Yorozuya T, Tanaka J. Comparison of the detrimental features of microglia and infiltrated macrophages in traumatic brain injury: A study using a hypnotic bromovalerylurea. Glia. doi: 10.1002/glia.23469. 2018.

 

  1. Islam A, Choudhury ME, Kigami Y, Utsunomiya R, Matsumoto S, Watanabe H, Kumon Y, Kunieda T, Yano H, Tanaka J. Sustained anti-inflammatory effects of TGF-β1 on microglia/macrophages. Biochimica et Biophysica Acta (BBA) – Molecular Basis of Disease 1864, 721-734 2018.

 

  1. Nishikawa M, Inoue A, Ohnishi T, Kohno S, Ohue S, Matsumoto S, Suehiro S, Yamashita D, Ozaki S, Watanabe H, Yano H, Takahashi H, Kitazawa R, Tanaka J, Kunieda T. Significance of Glioma Stem-Like Cells in the Tumor Periphery That Express High Levels of CD44 in Tumor Invasion, Early Progression, and Poor Prognosis in Glioblastoma. Stem Cells International, Article ID 5387041, 15 pages, https://doi.org/10.1155/2018/5387041, 2018.

 

  1. Kuwabara J, Umakoshi A, Abe N, Sumida Y, Ohsumi S, Usa E, Taguchi K, Choudhury ME, Yano H, Matsumoto S, Kunieda T, Takahashi H, Yorozuya T, Watanabe Y, Tanaka J. Truncated CD200 stimulates tumor immunity leading to fewer lung metastases in a novel Wistar rat metastasis model. Biochem. Biophys. Res. Commun. 496, 542-548, 2018.

 

  1. Kaminota T, Yano H, Shiota K, Nomura N, Yaguchi H, Kirino Y, Ohara K, Tetsumura I, Sanada T, Ugumori T, Tanaka J, Hato N. Elevated Na+/H+ exchanger-1 expression enhances the metastatic collective migration of head and neck squamous cell carcinoma cells. Biochem. Biophys. Res. Commun. 486, 101-107, 2017.

 

  1. Kawasaki S, Abe N, Ohtake F, Islam A, Choudhury ME, Utsunomiya R, Kikuchi S, Nishihara T, Kuwabara J, Yano H, Watanabe Y, Aibiki M, Yorozuya T, Tanaka J. Effects of hypnotic bromovalerylurea on microglial BV2 cells. J. Pharmacol. Sci. 134, 116-123, 2017.

 

  1. Yano Y, Yano H, Takahashi H, Yoshimoto K, Tsuda S, Fujiyama K, Shimizu YI, Motoie R, Ito M, Tanaka J, Ishii E Fukuda M. Goreisan suppresses cerebral edema associated with hypoxic-ischemic encephalopathy in juvenile rats possibly via inhibition of aquaporin 4. Evid Based Complement Alternat Med., Article ID 3209219, https://doi.org/10.1155/2017/3209219, 2017.

 

  1. Aono H, Choudhury ME, Higaki H, Miyanishi K, Kigami Y, Fujita K, Akiyama J, Takahashi H, Yano H, Kubo M, Nishikawa N, Nomoto M, Tanaka J. Microglia may compensate for dopaminergic neuron loss in experimental parkinsonism through selective elimination of glutamatergic synapses from the subthalamic nucleus. GLIA, 65, 1833-1847, 2017.

 

  1. Ito M, Takahashi H, Yano H, Shimizu YI, Yano Y, Ishizaki Y, Tanaka J, Ishii E, Fukuda M. High mobility group box 1 enhances hyperthermia-induced seizures and secondary epilepsy associated with prolonged hyperthermia-induced seizures in developing rats. Metabolic Brain Disease 32, 2095-2014, 2017.

 

  1. Higaki H, Choudhury ME, Kawamoto C, Miyamoto K, Islam A, Ishii Y, Miyanishi K, Takeda H, Seo N, Sugimoto K, Takahashi H, Yano H, Tanaka J. The hypnotic bromovalerylurea ameliorates 6-hydroxydopamineinduced dopaminergic neuron loss while suppressing expression of interferon regulatory factors by microglia. Neurochem. Int., 99, 158-168, 2016.

 

  1. Kobayashi K, Yano H, Umakoshi A, Matsumoto S, Mise A, Funahashi Y, Ueno Y, Kamei Y, Takada Y, Kumon Y, Ohnishi T, Tanaka J. A Truncated form of CD200 (CD200S) expressed on glioma cells prolonged survival in a gat glioma model by Induction of a dendritic cell-like phenotype in tumor-associated macrophages. Neoplasia, 18, 229-241, 2016.

 

  1. Nishioka R, Sugimoto K, Aono H, Mise A, Choudhury ME, Miyanishi K, Islama A, Fujita T, Takeda H, Takahashi H, Yano H, Tanaka J. Treadmill exercise ameliorates ischemia-induced brain edema while suppressing Na+/H+ exchanger 1 expression. Experimental Neurology 277, 150–161, 2016.

 

  1. Takahashi H, Inoue A, Kawabe Y, Hosokawa Y, Iwata S, Sugimoto K, Yano H, Yamashita D, Harada H, Kohno S, Ohue S, Ohnishi T, Tanaka J. Oct-3/4 promotes tumor angiogenesis through VEGF production in glioblastoma. Brain Tumor Pathol., 32, 31-40, 2015.

 

  1. Hosokawa Y, Takahashi H, Inoue A, Kawabe Y, Funahashi Y, Kameda K, Sugimoto K, Yano H, Harada H, Kohno S, Ohue S, Ohnishi T, Tanaka J. Oct-3/4 modulates the drug-resistant phenotype of glioblastoma cells through expression of ATP binding cassette transporter G2. Biochem. Biophys. Acta., 1850, 1197-1205, 2015.

 

  1. Kikuchi S, Nishihara T, Kawasaki S, Abe N, Kuwabara J, Choudhury ME, Takahashi H, Yano H, Nagaro T, Watanabe Y, Aibiki M, Tanaka J. The ameliorative effects of a hypnotic bromvalerylurea in sepsis. Biochem. Biophys. Res. Commun., 459, 319-326, 2015.

 

  1. Matsumoto S, Tanaka J, Yano H, Takahashi H, Sugimoto K, Ohue S, Inoue A, Aono H, Kusakawa A, Watanabe H, Kumon Y, Ohnishi T. CD200+ and CD200- macrophages accumulated in ischemic lesions of rat brain: the two populations cannot be classified as either M1 or M2 macrophages. J. Neuroimmunol. 282, 7-20, 2015.

 

  1. Ishii Y, Yamaizumi A, Kawakami A, Islam A, Choudhury ME, Takahashi H, Yano H, Tanaka J. Anti-inflammatory effects of noradrenaline on LPS-treated microglial cells: Suppression of NFκB nuclear translocation and subsequent STAT1 phosphorylation. Neurochem Int. 90, 56-66, 2015.

 

  1. Sugimoto K, Nishioka R, Ikeda A, Mise A, Takahashi H, Yano H, Kumon Y, Ohnishi T, Tanaka J. Activated microglia in a rat stroke model express NG2 proteoglycan in peri-infarct tissue through the involvement of TGF-β1. GLIA, 62: 185-198, 2014.

 

  1. Tei N, Tanaka J, Sugimoto K, Nishihara T, Nishioka R, Takahashi H, Yano H, Matsumoto S, Ohue S, Watanabe H, Kumon T, Ohnishi T. Expression of MCP-1 and fractalkine on endothelial cells and astrocytes may contribute to the invasion and migration of brain macrophages in ischemic rat brain lesions. J. Neurosci. Res. 91, 681-693, 2013.

 

  1. Kobayashi K, Takahashi K, Inoue A, Harada H, Toshimori S, Kobayashi Y, Goto K, Sugimoto K, Yano H, Ohnishi T, Tanaka J. Oct3/4 promotes migration and invasion of glioblastoma cells. J. Cell. Biochem., 113, 508-517, 2012.

 

  1. Mayorca-Guiliani A E, Yano H, Nakashiro K, Hamakawa H, Tanaka J. Premetastatic vasculogenesis in oral squamous cell carcinoma xenograft-draining lymph nodes. Oral Oncology, 48, 663-758, 2012.

 

  1. Nishihara T, Ochi M, Sugimoto K, Takahashi H, Yano H, Kumon Y, Ohnishi Y, Tanaka J. Subcutaneous injection containing IL-3 and GM-CSF ameliorates stab wound-induced brain injury in rats. J. Exp. Neurol., 229, 507-516, 2011.

 

  1. Nakata T, Kawachi K, Nagashima M, Yasugi T, Izutani H, Ryugo M, Okamura T, Shikata F, Imagawa H, Yano H, Takahashi H, Tanaka, J. Transient ischemia-induced paresis and complete paraplegia displayed distinct reactions of microglia and macrophages. Brain Res., 1420, 114-124, 2011.

 

  1. Choudhury M E, Sugimoto K, Kubo M, Nagai M, Nomoto M, Takahashi H, Yano H, Tanaka, J. A cytokine mixture of GM-CSF and IL-3 that induces a neuroprotective phenotype of microglia leading to amelioration of (6-OHDA)-induced Parkinsonism of rats. Brain Behav., 1, 26-43, 2011.

 

  1. Smirkin A, Matsumoto H, Takahashi H, Inoue A, Tagawa M, Ohue S, Watanabe H, Yano H, Kumon Y, Ohnishi T, Tanaka J. Iba1(+)/NG2(+) macrophage-like cells expressing a variety of neuroprotective factors ameliorate ischemic damage of the brain. J. Cereb. Blood Flow Metab., 30, 603-615, 2010.

 

  1. Inoue A, Takahashi H, Harada H, Kohno S, Ohue S, Kobayashi K, Yano H, Tanaka J, Ohnishi T. Cancer stem-like cells of glioblastoma characteristically express MMP-13 and display highly invasive activity. Int. J. Oncol., 37, 1121-1131, 2010.