PKR associates with 4.1R to promote anchorage-independent growth of hepatocellular carcinoma and lead to poor prognosis

Yusuke Okujima, Takao Watanabe, Takeshi Ito, Yasumichi Inoue, Yutaka Kasai, Yusuke Imai, Yoshiko Nakamura, Mitsuhito Koizumi, Osamu Yoshida, Yoshio Tokumoto, Masashi Hirooka, Masanori Abe, Ryosuke Kawakami, Takashi Saitou, Takeshi Imamura, Yoshinori Murakami, Yoichi Hiasa
Sci Rep. 2024 Nov 13;14(1):27768. doi: 10.1038/s41598-024-75142-5.
PMID: 39532917 PMCID: PMC11557841 DOI: 10.1038/s41598-024-75142-5

2024年

Trehalose prevents IL-4/IL-13-induced skin barrier impairment by suppressing IL-33 expression and increasing Nrf2 activation in human keratinocytes in vitro

Xiuju Dai, Yoichi Mizukami, Kenji Watanabe, Teruko Tsuda, Mutsumi Shidahara, Satoshi Yoshida, Kazuki Yatsuzuka, Ken Shiraishi, Hideki Mori, Masamoto Murakami, Ryosuke Kawakami, Takeshi Imamura, Yasuhiro Fujisawa, Jun Muto
J Invest Dermatol. 2024 Oct 7:S0022-202X(24)02175-4. doi: 10.1016/j.jid.2024.08.038. Online ahead of print.
PMID: 39384017 DOI: 10.1016/j.jid.2024.08.038

2024年

Heterozygous mutations in the straitjacket region of the latency-associated peptide domain of TGFB2 cause Camurati-Engelmann disease type II

Zheng Wang, Mitsuhiro Kometani, Leonid Zeitlin, Yael Wilnai, Akira Kinoshita, Koh-Ichiro Yoshiura, Hiroko Ninomiya, Takeshi Imamura, Long Guo, Jingyi Xue, Li Yan, Hirofumi Ohashi, Yann Pretemer, Shunsuke Kawai, Masaaki Shiina, Kazuhiro Ogata, Daniel H Cohn, Naomichi Matsumoto, Gen Nishimura, Junya Toguchida, Noriko Miyake, Shiro Ikegawa
J Hum Genet. 2024 Nov;69(11):599-605. doi: 10.1038/s10038-024-01274-1. Epub 2024 Jul 16.
PMID: 39014191 DOI: 10.1038/s10038-024-01274-1

2024年

Cellular senescence by loss of Men1 in osteoblasts is critical for age-related osteoporosis

Yuichiro Ukon, Takashi Kaito, Hiromasa Hirai, Takayuki Kitahara, Masayuki Bun, Joe Kodama, Daisuke Tateiwa, Shinichi Nakagawa, Masato Ikuta, Takuya Furuichi, Yuya Kanie, Takahito Fujimori, Shota Takenaka, Tadashi Yamamuro, Satoru Otsuru, Seiji Okada, Masakatsu Yamashita, Takeshi Imamura
Aging Cell. 2024 Oct;23(10):e14254. doi: 10.1111/acel.14254. Epub 2024 Jun 22.
PMID: 39384404 PMCID: PMC11464108 DOI: 10.1111/acel.14254