Profiling the inhibitory receptors LAG-3, TIM-3, and TIGIT in renal cell carcinoma reveals malignancy

Kimiharu Takamatsu, Nobuyuki Tanaka, Kyohei Hakozaki, Ryohei Takahashi, Yu Teranishi, Tetsushi Murakami, Ryohei Kufukihara, Naoya Niwa, Shuji Mikami, Toshiaki Shinojima, Takashi Sasaki, Yusuke Sato, Haruki Kume, Seishi Ogawa, Kazuhiro Kakimi, Takashi Kamatani, Fuyuki Miya, Tatsuhiko Tsunoda, Eriko Aimono, Hiroshi Nishihara, Kazuaki Sawada, Takeshi Imamura, Ryuichi Mizuno, Mototsugu Oya
Nat Commun. 2021 Sep 20;12(1):5547. doi: 10.1038/s41467-021-25865-0.
PMID: 34545095 PMCID: PMC8452744 DOI: 10.1038/s41467-021-25865-0

Multiplexed single‑cell pathology reveals the association of CD8 T‑cell heterogeneity with prognostic outcomes in renal cell carcinoma

Tetsushi Murakami, Nobuyuki Tanaka, Kimiharu Takamatsu, Kyohei Hakozaki, Keishiro Fukumoto, Tsukasa Masuda, Shuji Mikami, Toshiaki Shinojima, Kazuhiro Kakimi, Tatsuhiko Tsunoda, Kazuaki Sawada, Takeshi Imamura, Ryuichi Mizuno, Mototsugu Oya
Cancer Immunol Immunother. 2021 Oct;70(10):3001-3013. doi: 10.1007/s00262-021-03006-2. Epub 2021 Jul 14.
PMID: 34259900 DOI: 10.1007/s00262-021-03006-2

Wide Field Light-Sheet Microscopy with Lens-axicon Controlled Two-photon Bessel Beam Illumination

Sota Takanezawa, Takashi Saitou, Takeshi Imamura
Nat Commun. 2021 May 20;12(1):2979. doi: 10.1038/s41467-021-23249-y.
PMID: 34016994　PMCID: PMC8137944　DOI:10.1038/s41467-021-23249-y

Donor–acceptor–acceptor-type near-infrared fluorophores that contain dithienophosphole oxide and boryl groups: Effect of the boryl group on the nonradiative decay

Yoshiaki Sugihara, Naoto Inai, Thomas Baumgartner, Ryosuke Kawakami, Takashi Saitou, Takeshi Imamura, Masayasu Taki, Takeshi Yanai and Shigehiro Yamaguchi
Chem Sci. 2021 Mar 25;12(18):6333-6341. doi: 10.1039/d1sc00827g.
PMID: 34084431 PMCID: PMC8115064 DOI:10.1039/D1SC00827G

New fluorescent three-dimensional and deep-imaging technique confirms a direct relationship between the acrosyringium and vesicles/pustules of palmoplantar pustulosis

Masamoto Murakami, Ryosuke Kawakami, Yosuke Niko, Teruko Tsuda, Kazuki Yatsuzuka, Hideki Mori, Takeshi Imamura, Koji Sayama
J Dermatol Sci. 2021 May;102(2):130-132. doi: 10.1016/j.jdermsci.2021.03.004. Epub 2021 Mar 19.
PMID: 33810900 DOI: 10.1016/j.jdermsci.2021.03.004

Integrated Fluorescent Nanoprobe Design for High‐Speed In Vivo Two‐Photon Microscopic Imaging of Deep‐Brain Vasculature in Mice