2004年

Roles for the MH2 domain of Smad7 in the specific inhibition of transforming growth factor-beta superfamily signaling

Mochizuki T, Miyazaki H, Hara T, Furuya T, Imamura T, Watabe T, Miyazono K.
J Biol Chem. 2004 Jul 23;279(30):31568-74. Epub 2004 May 17.
PMID:15148321 DOI:10.1074/jbc.M313977200

PubMed

2004年

Smad6/Smurf1 overexpression in cartilage delays chondrocyte hypertrophy and causes dwarfism with osteopenia

Horiki M, Imamura T, Okamoto M, Hayashi M, Murai J, Myoui A, Ochi T, Miyazono K, Yoshikawa H, Tsumaki N.
J Cell Biol. 2004 May 10;165(3):433-45. Epub 2004 May 3.
PMID:15123739 PMCID:PMC2172180 DOI:10.1083/jcb.200311015

PubMed

2004年

Regulation of Transforming Growth Factor-Beta and Bone Morphogenetic Protein Signalling by Transcriptional Coactivator GCN5

Kahata K, Hayashi M, Asaka M, Hellman U, Kitagawa H, Yanagisawa J, Kato S, Imamura T, Miyazono K.
Genes Cells. 2004 Feb 13;9(2):143-51.
PMID:15009097 DOI:10.1111/j.1365-2443.2004.00706.x

PubMed

2004年

Endogenous TGF-beta signaling suppresses maturation of osteoblastic mesenchymal cells

Maeda S, Hayashi M, Komiya S, Imamura T, Miyazono K.
EMBO J. 2004 Feb 11;23(3):552-63. Epub 2004 Jan 29.
PMID:14749725 PMCID:PMC1271802 DOI:10.1038/sj.emboj.7600067

PubMed

2003年

Interaction with Smad4 is indispensable for suppression of BMP signaling by c-Ski

Takeda M, Mizuide M, Oka M, Watabe T, Inoue H, Suzuki H, Fujita T, Imamura T, Miyazono K, Miyazawa K.
Mol Biol Cell. 2004 Mar;15(3):963-72. Epub 2003 Dec 29.
PMID: 14699069 PMCID: PMC363053 DOI: 10.1091/mbc.e03-07-0478

PubMed

2003年

Arkadia amplifies TGF-beta superfamily signalling through degradation of Smad7

Koinuma D, Shinozaki M, Komuro A, Goto K, Saitoh M, Hanyu A, Ebina M, Nukiwa T, Miyazawa K, Imamura T, Miyazono K.
EMBO J. 2003 Dec 15;22(24):6458-70.
PMID:14657019 PMCID:PMC291827 DOI:10.1093/emboj/cdg632

PubMed

2003年

SB-431542 and Gleevec inhibit transforming growth factor-beta-induced proliferation of human osteosarcoma cells

Matsuyama S, Iwadate M, Kondo M, Saitoh M, Hanyu A, Shimizu K, Aburatani H, Mishima HK, Imamura T, Miyazono K, Miyazawa K.
Cancer Res. 2003 Nov 15;63(22):7791-8.
PMID:14633705 DOI: Published November 2003

PubMed

2003年

Differential ubiquitination defines the functional status of the tumor suppressor Smad4

Morén A, Hellman U, Inada Y, Imamura T, Heldin CH, Moustakas A.
J Biol Chem. 2003 Aug 29;278(35):33571-82. Epub 2003 Jun 5.
PMID:12794086 DOI:10.1074/jbc.M300159200

PubMed

2003年

Cooperative inhibition of bone morphogenetic protein signaling by Smurf1 and inhibitory Smads

Murakami G, Watabe T, Takaoka K, Miyazono K, Imamura T.
Mol Biol Cell. 2003 Jul;14(7):2809-17. Epub 2003 Apr 4.
PMID:12857866 PMCID:PMC165678 DOI:10.1091/mbc.e02-07-0441

PubMed

2003年

Regulation of TGF-beta signaling and its roles in progression of tumors

Miyazono K, Suzuki H, Imamura T.
Cancer Sci. 2003 Mar;94(3):230-4. Review
PMID:12824914 DOI:10.1111/j.1349-7006.2003.tb01425.x

PubMed