Degradation of the tumor suppressor Smad4 by WW and HECT domain ubiquitin ligases
Morén A, Imamura T, Miyazono K, Heldin CH, Moustakas A.
J Biol Chem. 2005 Jun 10;280(23):22115-23. Epub 2005 Apr 6.
PMID:15817471 DOI:10.1074/jbc.M414027200
NEDD4-2 (neural precursor cell expressed, developmentally down-regulated 4-2) negatively regulates TGF-beta (transforming growth factor-beta) signalling by inducing ubiquitin-mediated degradation of Smad2 and TGF-beta type I receptor
Kuratomi G, Komuro A, Goto K, Shinozaki M, Miyazawa K, Miyazono K, Imamura T.
Biochem J. 2005 Mar 8;386(3):461-70.
PMID:15496141 PMCID:PMC1134864 DOI:10.1042/BJ20040738
Vasorin, a transforming growth factor beta-binding protein expressed in vascular smooth muscle cells, modulates the arterial response to injury in vivo.
Ikeda Y1, Imai Y, Kumagai H, Nosaka T, Morikawa Y, Hisaoka T, Manabe I, Maemura K, Nakaoka T, Imamura T, Miyazono K, Komuro I, Nagai R, Kitamura T.
Proc Natl Acad Sci U S A. 2004 Jul 20;101(29):10732-7. Epub 2004 Jul 9.
PMID:15247411 PMCID:PMC490003 DOI:10.1073/pnas.0404117101
Negative regulation of transforming growth factor-beta (TGF-beta) signaling by WW domain-containing protein 1 (WWP1)
Komuro A, Imamura T, Saitoh M, Yoshida Y, Yamori T, Miyazono K, Miyazawa K.
Oncogene. 2004 Jun 28;23(41):6914-23.
PMID:15221015 DOI:10.1038/sj.onc.1207885
Coordinate regulation of cell growth and differentiation by TGF-beta superfamily and Runx proteins
Miyazono K, Maeda S, Imamura T.
Oncogene. 2004 May 24;23(24):4232-7. Review
PMID:15156178 DOI:10.1038/sj.onc.1207131
Roles for the MH2 domain of Smad7 in the specific inhibition of transforming growth factor-beta superfamily signaling
Mochizuki T, Miyazaki H, Hara T, Furuya T, Imamura T, Watabe T, Miyazono K.
J Biol Chem. 2004 Jul 23;279(30):31568-74. Epub 2004 May 17.
PMID:15148321 DOI:10.1074/jbc.M313977200
Smad6/Smurf1 overexpression in cartilage delays chondrocyte hypertrophy and causes dwarfism with osteopenia
Horiki M, Imamura T, Okamoto M, Hayashi M, Murai J, Myoui A, Ochi T, Miyazono K, Yoshikawa H, Tsumaki N.
J Cell Biol. 2004 May 10;165(3):433-45. Epub 2004 May 3.
PMID:15123739 PMCID:PMC2172180 DOI:10.1083/jcb.200311015
Regulation of Transforming Growth Factor-Beta and Bone Morphogenetic Protein Signalling by Transcriptional Coactivator GCN5
Kahata K, Hayashi M, Asaka M, Hellman U, Kitagawa H, Yanagisawa J, Kato S, Imamura T, Miyazono K.
Genes Cells. 2004 Feb 13;9(2):143-51.
PMID:15009097 DOI:10.1111/j.1365-2443.2004.00706.x
Endogenous TGF-beta signaling suppresses maturation of osteoblastic mesenchymal cells
Maeda S, Hayashi M, Komiya S, Imamura T, Miyazono K.
EMBO J. 2004 Feb 11;23(3):552-63. Epub 2004 Jan 29.
PMID:14749725 PMCID:PMC1271802 DOI:10.1038/sj.emboj.7600067
Interaction with Smad4 is indispensable for suppression of BMP signaling by c-Ski
Takeda M, Mizuide M, Oka M, Watabe T, Inoue H, Suzuki H, Fujita T, Imamura T, Miyazono K, Miyazawa K.
Mol Biol Cell. 2004 Mar;15(3):963-72. Epub 2003 Dec 29.
PMID: 14699069 PMCID: PMC363053 DOI: 10.1091/mbc.e03-07-0478