2003年

Chromosomal region maintenance 1 (CRM1)-dependent nuclear export of Smad ubiquitin regulatory factor 1 (Smurf1) is essential for negative regulation of transforming growth factor-beta signaling by Smad7

Tajima Y, Goto K, Yoshida M, Shinomiya K, Sekimoto T, Yoneda Y, Miyazono K, Imamura T.
J Biol Chem. 2003 Mar 21;278(12):10716-21. Epub 2003 Jan 7.
PMID: 12519765 DOI: 10.1074/jbc.M212663200

PubMed

2003年

Glypican-3, overexpressed in hepatocellular carcinoma, modulates FGF2 and BMP-7 signaling

Midorikawa Y, Ishikawa S, Iwanari H, Imamura T, Sakamoto H, Miyazono K, Kodama T, Makuuchi M, Aburatani H.
Int J Cancer. 2003 Feb 10;103(4):455-65. doi: 10.1002/ijc.10856.
PMID:12478660 DOI:10.1002/ijc.10856

PubMed

2002年

Two short segments of Smad3 are important for specific interaction of Smad3 with c-Ski and SnoN

Mizuide M, Hara T, Furuya T, Takeda M, Kusanagi K, Inada Y, Mori M, Imamura T, Miyazawa K, Miyazono K.
J Biol Chem. 2003 Jan 3;278(1):531-6. doi: 10.1074/jbc.C200596200. Epub 2002 Nov 7.
PMID: 12426322 DOI: 10.1074/jbc.C200596200

PubMed

2002年

Smurf1 regulates the inhibitory activity of Smad7 by targeting Smad7 to the plasma membrane

Suzuki C, Murakami G, Fukuchi M, Shimanuki T, Shikauchi Y, Imamura T, Miyazono K.
J Biol Chem. 2002 Oct 18;277(42):39919-25. Epub 2002 Jul 31.
PMID: 12151385 DOI: 10.1074/jbc.M201901200

PubMed

2002年

Functional heterogeneity of bone morphogenetic protein receptor-II mutants found in patients with primary pulmonary hypertension

Nishihara A, Watabe T, Imamura T, Miyazono K.
Mol Biol Cell. 2002 Sep;13(9):3055-63.Published Online:11 Jul 2002
PMID:12221115 PMCID:PMC124142 DOI:10.1091/mbc.e02-02-0063

PubMed

2001年

The N domain of Smad7 is essential for specific inhibition of transforming growth factor-beta signaling

Hanyu A, Ishidou Y, Ebisawa T, Shimanuki T, Imamura T, Miyazono K.
J Cell Biol. 2001 Dec 10;155(6):1017-27. Epub 2001 Dec 10.
PMID:11739411 PMCID:PMC2150897 DOI:10.1083/jcb.200106023

PubMed

2001年

Activation of the p21(CIP1/WAF1) promoter by bone morphogenetic protein-2 in mouse B lineage cells

Yamato K, Hashimoto S, Imamura T, Uchida H, Okahashi N, Koseki T, Ishisaki A, Kizaki M, Miyazono K, Ikeda Y, Nishihara T.
Oncogene. 2001 Jul 19;20(32):4383-92.
PMID: 11466619 DOI: 10.1038/sj.onc.1204572

PubMed

2001年

Ligand-dependent degradation of Smad3 by a ubiquitin ligase complex of ROC1 and associated proteins

Fukuchi M, Imamura T, Chiba T, Ebisawa T, Kawabata M, Tanaka K, Miyazono K.
Mol Biol Cell. 2001 May;12(5):1431-43.
PMID: 11359933 PMCID: PMC34595 DOI: 10.1091/mbc.12.5.1431

PubMed

2001年

Synergistic effects of different bone morphogenetic protein type I receptors on alkaline phosphatase induction

Aoki H, Fujii M, Imamura T, Yagi K, Takehara K, Kato M, Miyazono K.
J Cell Sci. 2001 Apr 15;114(Pt 8):1483-9.
PMID:11282024 DOI:10.1242/jcs.114.8.1483

PubMed

2001年

Smurf1 interacts with transforming growth factor-beta type I receptor through Smad7 and induces receptor degradation

Ebisawa T, Fukuchi M, Murakami G, Chiba T, Tanaka K, Imamura T, Miyazono K.
J Biol Chem. 2001 Apr 20;276(16):12477-80. Epub 2001 Feb 13.
PMID:11278251 DOI:10.1074/jbc.C100008200

PubMed