2019年

Rational Engineering of XCaMPs, a Multicolor GECI Suite for In Vivo Imaging of Complex Brain Circuit Dynamics

Masatoshi Inoue, Atsuya Takeuchi, Satoshi Manita, Shin-Ichiro Horigane, Masayuki Sakamoto, Ryosuke Kawakami, Kazushi Yamaguchi, Kouhei Otomo, Hiroyuki Yokoyama, Ryang Kim, Tatsushi Yokoyama, Sayaka Takemoto-Kimura, Manabu Abe, Michiko Okamura, Yayoi Kondo, Sean Quirin, Charu Ramakrishnan, Takeshi Imamura, Kenji Sakimura, Tomomi Nemoto, Masanobu Kano, Hajime Fujii, Karl Deisseroth, Kazuo Kitamura, Haruhiko Bito
Cell. 2019 May 16;177(5):1346-1360.e24. doi: 10.1016/j.cell.2019.04.007. Epub 2019 May 9.
PMID: 31080068 DOI: 10.1016/j.cell.2019.04.007

PubMed

2019年

Efficacy of an orally active small-molecule inhibitor of RANKL in bone metastasis

Yuta Nakai, Kazuo Okamoto, Asuka Terashima, Shogo Ehata, Jun Nishida, Takeshi Imamura, Takashi Ono, Hiroshi Takayanagi
Bone Res. 2019 Jan 3;7:1. doi: 10.1038/s41413-018-0036-5. eCollection 2019.
PMID: 30622830 PMCID: PMC6315020 DOI: 10.1038/s41413-018-0036-5

PubMed

2018年

Tissue Intrinsic Fluorescence Spectra-Based Digital Pathology of Liver Fibrosis by Marker-Controlled Segmentation

Saitou T, Takanezawa S, Ninomiya H, Watanabe T, Yamamoto S, Hiasa Y, Imamura T.
Front Med (Lausanne). 2018 Dec 11;5:350. eCollection 2018.
PMID: 30619861 PMCID: PMC6297145 DOI: 10.3389/fmed.2018.00350

PubMed

2018年

Craniofacial abnormality with skeletal dysplasia in mice lacking chondroitin sulfate N-acetylgalactosaminyltransferase-1

Ida-Yonemochi H, Morita W, Sugiura N, Kawakami R, Morioka Y, Takeuchi Y, Sato T, Shibata S, Watanabe H, Imamura T, Igarashi M, Ohshima H, Takeuchi K.
Sci Rep. 2018 Nov 20;8(1):17134.
PMID: 30459452 PMCID: PMC6244165 DOI: 10.1038/s41598-018-35412-5

PubMed

2018年

A Highly Photostable Near-Infrared Labeling Agent Based on a Phospha-rhodamine for Long-Term and Deep Imaging

Grzybowski M, Taki M, Senda K, Sato Y, Ariyoshi T, Okada Y, Kawakami R, Imamura T, Yamaguchi S.
Angew Chem Int Ed Engl. 2018 Aug 6;57(32):10137-10141. Epub 2018 Jul 16.
PMID: 29984448 DOI: 10.1002/anie.201804731

PubMed

2018年

In vivo optical imaging of cancer cell function and tumor microenvironment

Imamura T, Saitou T, Kawakami R.
Cancer Sci. 2018 Apr;109(4):912-918. Epub 2018 Mar 31. Review
PMID: 29465804 PMCID: PMC5891206 DOI: 10.1111/cas.13544

PubMed

2018年

Roles of protein kinase R in cancer: Potential as a therapeutic target

Watanabe T, Imamura T, Hiasa Y.
Cancer Sci. 2018 Apr;109(4):919-925. Epub 2018 Mar 23. Review
PMID: 29478262 PMCID: PMC5891186 DOI: 10.1111/cas.13551

PubMed

2018年

Quantitative Morphometry for Osteochondral Tissues Using Second Harmonic Generation Microscopy and Image Texture Information

Saitou T, Kiyomatsu H, Imamura T.
Sci Rep. 2018 Feb 12;8(1):2826.
PMID: 29434299 PMCID: PMC5809560 DOI: 10.1038/s41598-018-21005-9

PubMed

2017年

The HIV co-receptor CCR5 regulates osteoclast function

Lee JW, Hoshino A, Inoue K, Saitou T, Uehara S, Kobayashi Y, Ueha S, Matsushima K, Yamaguchi A, Imai Y, Iimura T.
Nat Commun. 2017 Dec 20;8(1):2226.
PMID: 29263385 PMCID: PMC5738403 DOI: 10.1038/s41467-017-02368-5

PubMed

2016年

Quantitative imaging of fibrotic and morphological changes in liver of non-alcoholic steatohepatitis (NASH) model mice by second harmonic generation (SHG) and auto-fluorescence (AF) imaging using two-photon excitation microscopy (TPEM)

Yamamoto S, Oshima Y, Saitou T, Watanabe T, Miyake T, Yoshida O, Tokumoto Y, Abe M, Matsuura B, Hiasa Y, Imamura T.
Biochem Biophys Rep. 2016 Sep 25;8:277-283. eCollection 2016 Dec.
PMID: 28955967 PMCID: PMC5614464 DOI: 10.1016/j.bbrep.2016.09.010

PubMed