研究について

研究について

業績一覧(2020年)

生化学グループ

  • Effects of AGXT2 variants on blood pressure and blood sugar among 750 older Japanese subjects recruited by the complete enumeration survey method. Yoshino Y, Kumon H, Mori T, Yoshida T, Tachibana A, Shimizu H, Iga JI, Ueno SI. BMC Genomics. 2021 Apr 20;22(1):287. doi: 10.1186/s12864-021-07612-3.
  • Neural precursor cells are decreased in the hippocampus of the delayed carbon monoxide encephalopathy rat model. Ochi S, Sekiya K, Abe N, Funahashi Y, Kumon H, Yoshino Y, Nishihara T, Boku S, Iga JI, Ueno SI. Sci Rep. 2021 Mar 18;11(1):6244. doi: 10.1038/s41598-021-85860-9.
  • Positional cloning and comprehensive mutation analysis identified a novel KDM2B mutation in a Japanese family with minor malformations, intellectual disability, and schizophrenia. Yokotsuka-Ishida S, Nakamura M, Tomiyasu Y, Nagai M, Kato Y, Tomiyasu A, Umehara H, Hayashi T, Sasaki N, Ueno SI, Sano A. J Hum Genet. 2021 Jun;66(6):597-606. doi: 10.1038/s10038-020-00889-4. Epub 2021 Jan 6.
  • PICALM mRNA Expression in the Blood of Patients with Neurodegenerative Diseases and Geriatric Depression. Kumon H, Yoshino Y, Funahashi Y, Mori H, Ueno M, Ozaki Y, Yamazaki K, Ochi S, Mori T, Iga JI, Nagai M, Nomoto M, Ueno SI. J Alzheimers Dis. 2021;79(3):1055-1062. doi: 10.3233/JAD-201046.
  • Positional cloning and comprehensive mutation analysis of a Japanese family with lithium-responsive bipolar disorder identifies a novel DOCK5 mutation. Umehara H, Nakamura M, Nagai M, Kato Y, Ueno SI, Sano A. J Hum Genet. 2021 Mar;66(3):243-249. doi: 10.1038/s10038-020-00840-7. Epub 2020 Sep 12.
  • Identifying Blood Transcriptome Biomarkers of Alzheimer’s Disease Using Transgenic Mice. Ochi S, Iga JI, Funahashi Y, Yoshino Y, Yamazaki K, Kumon H, Mori H, Ozaki Y, Mori T, Ueno SI. Mol Neurobiol. 2020 Dec;57(12):4941-4951. doi: 10.1007/s12035-020-02058-2. Epub 2020 Aug 20.
  • CTLA4 mRNA expression in blood is lower in schizophrenia, but not in affective disorders. Miyamoto K, Funahashi Y, Yoshino Y, Kawabe K, Yamazaki K, Ozaki Y, Mori Y, Ochi S, Iga JI, Ueno SI. Asian J Psychiatr. 2020 Aug;52:102112. doi: 10.1016/j.ajp.2020.102112. Epub 2020 Apr 19.
  • ABCA7 Gene Expression and Genetic Association Study in Schizophrenia. Yamazaki K, Yoshino Y, Kawabe K, Ibuki T, Ochi S, Mori Y, Ozaki Y, Numata S, Iga JI, Ohmori T, Ueno SI. Neuropsychiatr Dis Treat. 2020 Feb 13;16:441-446. doi: 10.2147/NDT.S238471. eCollection 2020.
  • DRD2 methylation to differentiate dementia with Lewy bodies from Parkinson’s disease. Ozaki Y, Yoshino Y, Yamazaki K, Ochi S, Iga JI, Nagai M, Nomoto M, Ueno SI. Acta Neurol Scand. 2020 Feb;141(2):177-182. doi: 10.1111/ane.13186. Epub 2019 Nov 16.
  • Analysis of methylation and -141C Ins/Del polymorphisms of the dopamine receptor D2 gene in patients with schizophrenia. Funahashi Y, Yoshino Y, Yamazaki K, Ozaki Y, Mori Y, Mori T, Ochi S, Iga JI, Ueno SI. Psychiatry Res. 2019 Aug;278:135-140. doi: 10.1016/j.psychres.2019.06.001. Epub 2019 Jun 1.
  • Differential expression of the ghrelin-related mRNAs GHS-R1a, GHS-R1b, and MBOAT4 in Japanese patients with schizophrenia. Nakata S, Yoshino Y, Okita M, Kawabe K, Yamazaki K, Ozaki Y, Mori Y, Ochi S, Iga JI, Ueno SI. Psychiatry Res. 2019 Feb;272:334-339. doi: 10.1016/j.psychres.2018.12.135. Epub 2018 Dec 26.
  • Ghrelin cascade changes in the peripheral blood of Japanese patients with Alzheimer’s disease. Yoshino Y, Funahashi Y, Nakata S, Ozaki Y, Yamazaki K, Yoshida T, Mori T, Mori Y, Ochi S, Iga JI, Ueno SI. J Psychiatr Res. 2018 Dec;107:79-85. doi: 10.1016/j.jpsychires.2018.10.011. Epub 2018 Oct 18.
  • TREM1 mRNA Expression in Leukocytes and Cognitive Function in Japanese Patients with Alzheimer’s Disease. Sao T, Yoshino Y, Yamazaki K, Ozaki Y, Mori Y, Ochi S, Yoshida T, Mori T, Iga JI, Ueno SI. J Alzheimers Dis . 2018;64(4):1275-1284. doi: 10.3233/JAD-180418.
  • MEF2C mRNA expression and cognitive function in Japanese patients with Alzheimer’s disease. Sao T, Yoshino Y, Yamazaki K, Ozaki Y, Mori Y, Ochi S, Yoshida T, Mori T, Iga JI, Ueno SI. Psychiatry Clin Neurosci. 72:160-167, 2018.
  • TOMM40 and APOE Gene Expression and Cognitive Decline in Japanese Alzheimer’s Disease Subjects. Mise A, Yoshino Y, Yamazaki K, Ozaki Y, Sao T, Yoshida T, Mori T, Mori Y, Ochi S, Iga JI, Ueno SI. J Alzheimers Dis. 60: 1107–1117, 2017.
  • DNA Methylation Changes in Intron 1 of Triggering Receptor Expressed on Myeloid Cell 2 in Japanese Schizophrenia Subjects. Yoshino Y, Ozaki Y, Yamazaki K, Sao T, Mori Y, Ochi S, Iga JI, Ueno SI. Front Neurosci. 11: 275, 2017.
  • INPP5D mRNA Expression and Cognitive Decline in Japanese Alzheimer’s Disease Subjects. Yoshino Y, Yamazaki K, Ozaki Y, Sao T, Yoshida T, Mori T, Mori Y, Ochi S, Iga JI, Ueno SI. J Alzheimers Dis. 58: 687-694, 2017.
  • Elevated mRNA expression of CASPR3 in patients with schizophrenia. Okita M, Yoshino Y, Iga JI, Ueno SI. Nord J Psychiatry 71:312-314, 2017.
  • DNA methylation changes at TREM2 intron 1 and TREM2 mRNA expression in patients with Alzheimer’s disease. Ozaki Y, Yoshino Y, Yamazaki K, Sao T, Mori Y, Ochi S, Yoshida T, Mori T, Iga JI, Ueno SI. J Psychiatr Res 92:74-80, 2017.
  • Gene Expression and Methylation Analysis of ABCA7 in Patients with Alzheimer’s Disease. Yamazaki K, Yoshino Y, Mori T, Yoshida T, Ozaki Y, Sao T, Mori Y, Ochi S, Iga JI, Ueno SI. J Alzheimers Dis 57: 171-181, 2017.
  • DNA methylation changes at SNCA intron 1 in patients with dementia with Lewy bodies. Funahashi Y, Yoshino Y, Yamazaki K, Mori Y, Mori T, Ozaki Y, Sao T, Ochi S, Iga JI, Ueno SI. Psychiatry Clin Neurosci 71:28-35,2017.

神経心理グループ

  • Study design and baseline characteristics of a population-based prospective cohort study of dementia in Japan: the Japan Prospective Studies Collaboration for Aging and Dementia (JPSC-AD). Ninomiya T, Nakaji S, Maeda T, Yamada M, Mimura M, Nakashima K, Mori T, Takebayashi M, Ohara T, Hata J, Kokubo Y, Uchida K, Taki Y, Kumagai S, Yonemoto K, Yoshida H, Muto K, Momozawa Y, Akiyama M, Kubo M, Ikeda M, Kanba S, Kiyohara Y; JPSFC-AD Study Group. Environ Health Prev Med. 2020 Oct 31;25(1):64. doi: 10.1186/s12199-020-00903-3.
  • Prevalence of possible idiopathic normal pressure hydrocephalus in older inpatients with schizophrenia: a replication study. Yoshino Y, Yoshida T, Morino H, Nakamura M, Abe M, Omachi H, Inoue S, Miyoshi Y, Tachibana Y, Yamauchi N, Takeda N, Mizobuchi M, Ozaki Y, Ochi S, Iga J, Ueno SI. BMC Psychiatry. 2020 Jun 1;20(1):273. doi: 10.1186/s12888-020-02690-1.
  • Improvement of Visuo-spatial Function Assessed by Raven’s Colored Progressive Matrices in Dementia with Lewy Bodies by Donepezil Treatment. Yoshino Y, Mori T, Yoshida T, Toyota Y, Shimizu H, Iga JI, Nishitani S, Ueno SI. Clin Psychopharmacol Neurosci. 15: 243-247, 2017.

児童青年期精神医学グループ

  • Mental health and sleep habits/problems in children aged 3-4 years: a population study. Horiuchi F, Kawabe K, Oka Y, Nakachi K, Hosokawa R, Ueno SI. Biopsychosoc Med. 2021 May 20;15(1):10. doi: 10.1186/s13030-021-00213-2.
  • Association between Internet Addiction and Application Usage among Junior High School Students: A Field Survey. Kawabe K, Horiuchi F, Hosokawa R, Nakachi K, Ueno SI. Int J Environ Res Public Health. 2021 May 1;18(9):4844. doi: 10.3390/ijerph18094844.
  • Identification of aberrant innate and adaptive immunity based on changes in global gene expression in the blood of adults with autism spectrum disorder. Horiuchi F, Yoshino Y, Kumon H, Hosokawa R, Nakachi K, Kawabe K, Iga JI, Ueno SI. J Neuroinflammation. 2021 Apr 30;18(1):102. doi: 10.1186/s12974-021-02154-7.
  • Parent-Adolescent Agreement on Adolescents’ Emotional and Behavioral Problems Assessed by the Strengths and Difficulties Questionnaire. Kawabe K, Horiuchi F, Uno H, Nakachi K, Hosokawa R, Oka Y, Ueno SI. Glob Pediatr Health. 2021 Mar 12;8:2333794X211001245. doi: 10.1177/2333794X211001245. eCollection 2021.
  • The Association between Autistic Traits and Sleep Habits/Problems in Toddlers. Horiuchi F, Kawabe K, Oka Y, Nakachi K, Hosokawa R, Ueno SI. Dev Neuropsychol. 2020 Dec 18;45(7-8):485-495. doi: 10.1080/87565641.2020.1865357. Epub 2020 Dec 25.
  • Excessive and Problematic Internet Use During the Coronavirus Disease 2019 School Closure: Comparison Between Japanese Youth With and Without Autism Spectrum Disorder. Kawabe K, Hosokawa R, Nakachi K, Yoshino A, Horiuchi F, Ueno SI. Front Public Health. 2020 Dec 17;8:609347. doi: 10.3389/fpubh.2020.609347. eCollection 2020.
  • Prevalence of Internet addiction in Japan: Comparison of two cross-sectional surveys. Kawabe K, Horiuchi F, Nakachi K, Hosokawa R, Ueno SI. Pediatr Int. 2020 Aug;62(8):970-975. doi: 10.1111/ped.14250. Epub 2020 Jul 28.
  • Sleep Habits and Electronic Media Usage in Japanese Children: A Prospective Comparative Analysis of Preschoolers. Horiuchi F, Oka Y, Kawabe K, Ueno SI. Int J Environ Res Public Health. 2020 Jul 17;17(14):5189. doi: 10.3390/ijerph17145189.
  • Making a brochure about coronavirus disease (COVID-19) for children with autism spectrum disorder and their family members. Kawabe K, Hosokawa R, Nakachi K, Yoshino A, Horiuchi F, Ueno SI. Psychiatry Clin Neurosci. 2020 Sep;74(9):498-499. doi: 10.1111/pcn.13090. Epub 2020 Jul 10.
  • School refusal and bullying in children with autism spectrum disorder. Ochi M, Kawabe K, Ochi S, Miyama T, Horiuchi F, Ueno SI. Child Adolesc Psychiatry Ment Health. 2020 May 7;14:17. doi: 10.1186/s13034-020-00325-7. eCollection 2020.
  • Combination treatment with guanfacine extended release and blonanserin for Tourette’s syndrome comorbid with attention deficit hyperactivity disorder. Kawabe K, Horiuchi F, Ueno SI. Psychiatry Clin Neurosci. 2019 Dec;73(12):762-763. doi: 10.1111/pcn.12935. Epub 2019 Oct 23.
  • Association between Sleep Habits and Problems and Internet Addiction in Adolescents. Kawabe K, Horiuchi F, Oka Y, Ueno SI. Psychiatry Investig. 2019 Aug;16(8):581-587. doi: 10.30773/pi.2019.03.21.2. Epub 2019 Aug 8.
  • Internet addiction and attention-deficit / hyperactivity disorder symptoms in adolescents with autism spectrum disorder. Kawabe K, Horiuchi F, Miyama T, Jogamoto T, Aibara K, Ishii E, Ueno SI. Res Dev Disabil. 2019 Jun;89:22-28. doi: 10.1016/j.ridd.2019.03.002. Epub 2019 Mar 14.
  • Neurocognitive assessment of children with neurodevelopmental disorders: Preliminary findings. Kawabe K, Horiuchi F, Kondo S, Matsumoto M, Seo K, Oka Y, Ueno SI. Pediatr Int. 2018 Sep;60(9):820-827. doi: 10.1111/ped.13662.
  • Suvorexant for the Treatment of Insomnia in Adolescents. Kawabe K, Horiuchi F, Ochi M, Nishimoto K, Ueno SI, Oka Y. J Child Adolesc Psychopharmacol. 27: 792-795, 2017.

その他

日本語文献

  • 愛媛大学病院精神科外来における成人期発達障害に対する診療パスの予備的研究 河邉憲太郎,越智麻里奈,松本美希,近藤静香,伊藤瑠璃子,芳野歩美,妹尾香苗,堀内史枝,上野修一 精神医学 60巻 5号 Page 545-557 (2018.05)
  • 非寛解うつ病に対して切り替えか,増強かー高齢者の非寛解うつ病で考えておきたいこと 越智紳一郎, 上野修一 臨床精神薬理 20巻 5号 Page 585-588 (2017.05)
  • うつ病維持療法ガイドライン 伊賀淳一 臨床精神薬理 20巻 5号 Page 505-512 (2017.5)
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