小児医療を通じて未来を守る

業績集

愛媛大学小児科業績 2016

【論文・英文原著】

1. Muramatsu H, Okuno Y, Yoshida K, Shiraishi Y, Doisaki S, Narita A,Sakaguchi H, Kawashima N, Wang X, Xu Y, Chiba K, Tanaka H, Hama A, Sanada M, Takahashi Y, Kanno H, Yamaguchi H, Ohga S, Manabe A, Harigae H, Kunishima S, Ishii E, Kobayashi M, Koike K, Watanabe K, Ito E, Takata M, Yabe M, Ogawa S, Miyano M, Kojima S (2016) Clinical utility of next-generation sequencing for inherited bone marrow failure syndromes.Genet Med (in press)

2. Umeda K, Adachi S, Horikoshi Y, Imai K, Terui K, Endo M, Mitsui T, Kato K, Koh K, Kajiwara R, Ito R, Otsuka Y, Inoue M, Ishii E, Yabe H (2016) Allogeneic hematopoietic stem cell transplantation for Chediak-Higashi syndrome. Pediatr Transplant 20: 271-275

3. Kurosawa H, Tanizawa A, Tono C, Watanabe A, Shima H, Ito M, Yuza Y, Hotta N, Muramatsu H, Okada M, Kajiwara R, Moriya Saito A, Mizutani S, Adachi S, Horibe K, Ishii E, Shimada H (2016) Leukostasis in children and adlescents with chronic myeloid leukemia: Japanese Pediatric Leukemia/Lymphoma Study Group. Pediatr Blood Cancer 63: 406-411

4. Hori M, Yasumi T, Shimodera S, Shibata H, Hiejima E, Oda H, Izawa K, Kawai T, Ishimura M, Nakano N, Shirakawa R, Nishikomori R, Takada H, Morita S, Horiuchi H , Ohara O, Ishii E, Heike T (2016) A CD57+ CTL degranulation assay effectively identifies familial hemophagocytic lymphohistiocytosis type 3 patients. J Clin Immunol (in press)

5. Morimoto A, Shioda Y, Imamura T, Kudo K, Kawaguchi H, Sakashita K, Yasui M, Koga Y, Kobayashi R, Ishii E, Fujimoto J, Horibe K, Bessho F, Tsunematsu Y, Imashuku S (2016) Intensified and prolonged therapy comprising cytarabine, vincristine and prednisolone improves outcome in patients with multisystem Langerhans cell histiocytosis: Results of the Japan Langerhans Cell Histiocytosis Study Group-02 Protocol Study. Int J Hematol 104: 99-109

6. Imamura T, Kiyokawa N, Kato M, Imai C, Okamoto Y, Yano M, Ohki K, Yamashita Y, Kodama Y, Saito A, Mori M, Ishimaru S, Deguchi T, Hashii Y, Shimomura Y, Hori T, Kato K, Goto H, Ogawa C, Koh K, Taki T, Manabe A, Sato A, Kikuta A, Adachi S, Horibe K, Ohara A, Watanabe A, Kawano Y, Ishii E, Shimada H (2016) Characterization of pediatric Philadelphia-negative B-cell precursor acute lymphoblastic leukemia with kinase fusions in Japan. Blood Cancer J 6: e419

7. Kodama Y, Manabe A, Kawasaki H, Kato I, Kato K, Sato A, Matsumoto K, Kato, M, Hiramatsu H, Sano H, Kaneko T, Oda M, Saito AM, Adachi S, Horibe K, Mizutani S, Ishii E, Shimada H (2016) Salvage therapy for children with relapsed or refractory Philadelphia chromosome-positive acute lymphoblastic leukemia. Pediatr Blood Cancer (in press)

8. Gao W, Higaki T, Eguchi-Ishimae M, Iwabuki H, Wu Z, Yamamoto E, Takata H, Ohta M, Imoto I, Ishii E, Eguchi M (2016) DGCR6 at proximal part of DiGeorge critical region is involved in conotruncal heart defects. Hum Genome Varia Feb 12; 2: 15004.

9. Poitras JL, Heiser D, Li L, Nguyen B, Nagai K, Duffield AS, Gamper C, Small D. (2016) Dnmt3a deletion cooperates with the Flt3/ITD mutation to drive leukemogenesis in a murine model. Oncotarget (in press)

10. Ichimura T, Yoshida K, Okuno Y, Yujiri T, Nagai K, Nishi M, Shiraishi Y, Ueno H, Toki T, Chiba K, Tanaka H, Muramatsu H, Hara T, Kanno H, Kojima S, Miyano S, Ito E, Ogawa S, Ohga S.(2016) Diagnostic challenge of Diamond-Blackfan anemia in mothers and children by whole-exome sequencing. Int J Hematol (in press)

11. Fujiwara H, Ochi T, Ochi F, Miyazaki Y, Asai H, Narita M, Okamoto S, Mineno J, Kuzushima K, Shiku H, Yasukawa M (2015) Antileukemia multifunctionality of CD4+ T cells genetically engineered by HLA class I-restricted and WT1-specific T-cell receptor gene transfer. Leukemia. 29: 2393-2401

12. Tanaka H, Fujiwara H, Ochi F, Tanimoto K, Casey N, Okamoto S, Mineno J, Kuzushima K, Shiku H, Sugiyama T, Barrett J, Yasukawa M (2016) Development of engineered T cells expressing a chimeric CD16-CD3ζ receptor to improve the clinical efficacy of mogamulizumab therapy against adult T cell leukemia. Clin Cancer Res (in press)

13. Higaki T, Chisaka T, Moritani T, Ohta M, Takata H, Yamauchi T, Ochi F, Yamaguchi Y, Konishi K, Yamamoto E, Eguchi-ishimae M, Eguchi M, Mitani Y, Ishii E (2016) Installation of multiple AED to prevent sudden death in school-aged children. Pediatr Int (in press)

14. Ishida Y, Higaki T, Hayashi M, et al (2016) Factors associated with the specific worries of childhood cancer survivors: Cross-sectional survey in Japan. Pediatr Int 58:331-7

15. Yamamoto E, Higaki T, Nakano T, Watanabe R, Konishi K, Takahashi Y, Ishida Y, Ishii E (2016) Clinical Investigation of Kawasaki Disease in Patients aged Five years or Older at Onset. Jacobs J Pediatr (in press)

16. Tomita H, Higaki T, Kobayashi T, Fujii T, Fujimoto K (2015) Stenting for curved lesions using a novel curved balloon; Preliminary experimental study. J Cardiology 66: 120-124

17. Chisaka T, Mogi M, Nakaoka H, Kan-No H, Tsukuda K, Wang XL, Bai HY, Shan BS, Kukida M, Iwanami J, Higaki T, Ishii E, Horiuchi M (2016) Low-Protein Diet-Induced Fetal Growth Restriction Leads to Exaggerated Proliferative Response to Vascular Injury in Postnatal Life. Am J Hypertens 29: 54-62

18. Kukida M, Mogi M, Ohshima K, Nakaoka H, Iwanami J, Kanno H, Tsukuda K, Chisaka T, Min LJ, Wang XL, Bai HY, Shan BS, Higaki A, Yamauchi T, Okura T, Higaki J, Horiuchi M. (2016) Angiotensin II Type 2 Receptor Inhibits Vascular Intimal Proliferation With Activation of PPARγ. Am J Hypertens. 29: 727-736

19. Mogi M, Kohara K, Nakaoka H, Kan-No H, Tsukuda K, Wang XL, Chisaka T, Bai HY, Shan BS, Kukida M, Iwanami J, Miki T, Horiuchi M. (2016) Diabetic mice exhibited a peculiar alteration in body composition with exaggerated ectopic fat deposition after muscle injury due to anomalous cell differentiation. J Cachexia Sarcopenia Muscle. 7: 213-24

20. Abe Y, Sakai T, Okumura A, Akaboshi S, Fukuda M, Haginoya K, Hamano S, Hirano K, Kikuchi K, Kubota M, Lee S, Maegaki Y, Sanefuji M, Shimozato S, Suzuki M, Suzuki Y, Takahashi M, Watanabe K, Mizuguchi M, Yamanouchi H. (2016) Manifestations and characteristics of congenital adrenal hyperplasia-associated encephalopathy. Brain Dev 38: 638-47

21. Jogamoto T, Yamamoto Y, Fukuda M, Suzuki Y, Imai K, Takahashi Y, Inoue Y, Ohtsuka Y. (2016) Add-on stiripentol elevates serum valproate levels in patients with or without concomitant topiramate therapy. Epilepsy Res (in press)

22. Hamada J, Onum H, Ochi F, Hirai H, Takemoto K, Miyoshi A, Matsushita M, Kadota Y, Ohashi J, Kawamura R, Takata Y, Nishida W, Hashida S, Ishii E, Osawa H. (2016) Endoplasmic reticulum stress induced by tunicamycin increases resistin mRNA through the PERK-ATF4-CHOP pathway in THP-1 human monocytes. J Diabetes Invest 7: 312-323

23. Ayabe T, Fukami M, Ogata T, Kawamura T, Urakami T, Kikuchi N, Yokota I, Ihara K, Takemoto K, Mukai T, Nishii A, Kikuchi T, Mori T, Shimura N, Sasaki G, Kizu R, Takubo N, Soneda S, Fujisawa T, Takaya R, Kizaki Z, Kanzaki S, Hanaki K, Matsuura N, Kasahara Y, Kosaka K, Takahashi T, Minamitani K, Matsuo S, Mochizuki H, Kobayashi K, Koike A, Horikawa R, Teno S, Tsubouchi K, Mochizuki T, Igarashi Y, Amemiya S, Sugihara S; The Japanese Study Group of Insulin Therapy for Childhood and Adolescent Diabetes (JSGIT). Variants associated with autoimmune Type 1 diabetes in Japanese children: Implications for age-specific effects of cis-regulatory haplotypes at 17q12-q21. Diabet Med (in press)

24. Ihara K, Toda N, Fukano C, Ayabe T, Fukami M, Ogata T, Kawamura T, Urakami T, Kikuchi N, Yokota I, Takemoto K, Mukai T, Nishii A, Kikuchi T, Mori T, Shimura N, Sasaki G, Kizu R, Takubo N, Soneda S, Fujisawa T, Takaya R, Kizaki Z, Kanzaki S, Hanaki K, Matsuura N, Kasahara Y, Kosaka K, Takahashi T, Minamitani K, Matsuo S, Mochizuki H, Kobayashi K, Koike A, Horikawa R, Teno S, Tsubouchi K, Mochizuki T, Igarashi Y, Amemiya S and Sugihara S; The Japanese Study Group of Insulin Therapy for Childhood and Adolescent Diabetes (JSGIT). FUT2 Nonsecretor Status Links Type 1 Diabetes Susceptibility in Japanese children. Diabet Med (in press)

25. Ishida Y, Tezuka M, Hayashi M, et al (2016) Japanese childhood cancer survivors’ readiness for care as adults: a cross-sectional survey using the Transition Scales. Psychooncology (in press)

26. Ishida Y, Qiu D, Maeda M, et al (2016) Secondary cancers after a childhood cancer diagnosis: a nationwide hospital-based retrospective cohort study in Japan. Int J Clin Oncol 21:506-16

27. Takenoshita S, Nomura K, Ohde S, Deshpande GA, Sakamoto H, Yoshida H, Urayama K, Bito S, Ishida Y, Shimbo T, Matsui K, Fukui T, Takahashi O (2016) hav ing a Mentor or a Doctoral Degree Is Helpful for Mid-Career Physicians to Publish Papers in Peer-Reviewed Journals.Tohoku J Exp Med (In press)

28. Daida A, Yoshihara H, Inai, I, Hasegawa D, Ishida Y, Urayama KY., Manabe A (2016) Risk factors for hospital-acquired Clostridium difficile infection among pediatric patients with cancer. J Pediatr Hematol Oncol (In press)

29. Mukaino A, Nakane S, Higuchi O, Nakamura H, Miyagi T, Shiroma K, Tokashiki T, Fuseya Y, Ochi K, Umeda M, Nakazato T, Akioka S, Maruoka H, Hayashi M, Igarashi S, Yokoi K, Maeda Y, Sakai W, Matsuo H, Kawakami A (2016) Insights from the ganglionic acetylcholine receptor autoantibodies in patients with Sjogren’s syndrome. Modern Rheumatol 26:708-715

愛媛大学小児科業績 2016

【論文・英文症例報告】

1.Ochi F, Tauchi H, Moritani K, Yonezawa S, Miyamoto H, Suemori K, Ishii E (2016) Rothia mucilaginosa infection in a child with acute lymphoblastic leukemia: a case report. Pediatr Blood Cancer (in press)

2.Hino H, Fukuda M, Suzuki Y, Ishii E (2016) Biphasic cuirass ventilation for treatment of an air leak
after pneumothorax in a patient with nemaline myopathy: a case report. J Anesthesia 30: 1087-1090

3.Tezuka Y, Fukuda M, Watanabe S, Nakano T, Okamoto K, Kuzume K, Yano Y, Eguchi M, Ishimae M, Ishii E, Miyazaki T (2016) Histological characterisation of visceral changes in a patient with type 2 Gaucher disease treated with enzyme replacement therapy. Blood Cells Mol Dis (in press)

4.Tezuka M, Ohta M, Ochi F, Chisaka T, Higaki T, Ishii E (2016) Successful treatment by coil embolization for infantile hemangioma with Kasabach-Meritt syndrome. Pediatric Int (in press)

5.Kojima A, Okamura T, Shikata F, Uchita S, Yamauchi T, Ohta M, Mori H, Tozawa A, Fujii S, Kawanishi Y, Higaki T, Izutani H (2016) Staged Repair of Complete Sternal Cleft and Interrupted Aortic Arch Associated With PHACES Syndrome in a Very Low Birth Weight Infant. Int Surg (in press)

6.Shikata F, Okamura T, Higaki T, Okura M, Kojima A, Uchita S, Izutani H. (2016) Aortic Coarctation 28 Days after an Arterial Switch Operation in a Neonate. Tex Heart Inst J 43: 354-356.

7.Morino T, Ogata T, Horiuchi H, Yamaoka S, Fukuda M, Miura H. (2016) Eight years of follow-up after laminectomy of calcium pyrophosphate crystal deposition in the cervical yellow ligament of patient with Coffin-Lowry syndrome: A case report. Medicine (Baltimore) 95:e4468.

8.Nagai K, Suyama Y, Koga D, Nishi M, Iida C, Tashiro K, Danjo A, Kai K, Matsuo M (2016) Anaplastic Lymphoma Kinase-Positive Anaplastic Large Cell Lymphoma with Cardiac Metastasis and Arterial Tumor Embolisms during First-Course Chemotherapy. Case Rep Oncol. 17; 9: 440-446.

9.Akaike S, Kamoi K, Tezuka M, Tomizawa D, Yoshimura R, Takagi M, Ohno-Matsui K (2016) Ocular manifestation in Myeloid/NK cell precursor acute leukemia: A case diagnosed by the flow cytometry and PCR form aqueous humor. Medline (in press)

愛媛大学小児科業績 2016

【原著・和文】

1.竹本幸司、中矢隆大、加藤文徳、牧野景、濱田淳平、戒能幸一、伊藤卓夫、藤澤由樹、石井榮一 (2016) 正期産、人工栄養児に発症したearly hypocalcemic typeのビタミンD欠乏性低カルシウム血症の1ヵ月男児例、ホルモンと臨床、特集小児内分泌学の進歩2015、62: 83-86

2.岡本健太郎、福田光成 (2016) 小児神経専門医へのインターネット上のアクセシビリテイに関する調査. 脳と発達 48: 290-291

3.越智史博,水野由美,青木知信(2017) 血液培養陽性となった黄色ブドウ球菌感染症の臨床像. 小児感染免疫.(In press)

4.元木崇裕、中川栄二、小一原玲子、高橋幸利、竹下絵里、石山昭彦、齋藤貴志、小牧宏文、須貝研司、佐々木征行(2016)免疫グロブリン治療が奏功したてんかん性脳症例. 脳と発達 2016;48:277-81.

5.石田也寸志 手束真理, 林三枝, 等 (2016) 小児がん経験者の成人医療移行への準備状況に関する横断的実態調査. 日本小児血液・がん学会雑誌 53, 2016 (印刷中)

6.歌野智之, 田中庸一, 木津純子, 神谷尚宏, 小川千登世, 石田也寸志, 細谷亮太, 真部淳 (2016)小児急性リンパ性白血病の維持療法期間におけるメルカプトプリン及びメトトレキサート投与量の推移 単施設における検討. 日本小児血液・がん学会雑誌 53:399-402

7.苔口知樹, 神薗淳司, 竹井寛和, 小林加奈, 増井美苗, 富田一郎, 石橋紳作, 天本正乃, 市川光太郎 (2016) 小児肘内障に対する超音波診断と「滑膜ひだ陥入」所見の有用性. 日本小児救急医学会雑誌 15: 14-17

8.苔口知樹, 神薗淳司, 増井美苗, 松島卓也, 山根浩昌, 石橋紳作, 今村徳夫, 天本正乃, 市川光太郎 (2016) 乳幼児発熱性疾患における体温1℃上昇あたりの心拍数と呼吸数の変化率に関する検討. 日本小児救急医学会雑誌 15: 392-396

9.苔口知樹, 志村紀彰, 神薗淳司, 村上珠菜, 山根浩昌, 今村徳夫, 石橋紳作, 天本正乃, 市川光太郎 (2016)川崎病に4回罹患後にYersinia pseudotuberculosis感染症を起こした1男児例. 小児内科 48: 116-121

10.苔口知樹, 小林加奈, 村上珠奈, 増井美苗, 富田一郎, 金奉吉, 石橋紳作, 神薗淳司, 天本正乃, 市川光太郎 (2016) 細菌性髄膜炎に4回罹患した経篩骨型頭蓋底脳瘤の男児例. 小児内科 48: 638-642

11.西村幸士 楠目和代 加賀田優紀 (2016)小児蕁麻疹患者の凝固機能についての検討 アレルギー (2016) 第65巻 2号 118-122

12.桑原優、楠目和代 (2016) NA-623N○Rにおける呼気一酸化窒素濃度オンライン測定とオフライン測定の比較とオフライン測定の時間的安定性に関する検討  日本小児呼吸器学会雑誌 第27巻 第2号 (in press)

13.長谷幸治、林正俊 (2016) シクロスポリンAが奏効している二つのWT1遺伝子変異を有するDiffuse mesangial sclerosisの一例. 日児腎誌 29:39-44

14.林正俊 (2016)市立宇和島病院小児科の患者の動きからみえる地域の抱える問題. 南予医学雑誌 17: 1-6

愛媛大学小児科業績 2016

【著書】

1.堀浩樹、石井榮一 (2016) 小児がん臨床研究プロトコル作成の手順.よくわかる臨床研究―小児がんー.pp137-144

2.Lehmberg K, Ochi F, Ishii E, Nichols K (2016) HLH associated with malignancies and EBV infection. Book on Histiocytoses (in press)

3.檜垣高史 (2015) こどもが元気になる在宅ケア 「心疾患」南山堂、梶原厚子 編 (2016) 印刷中

4.檜垣高史 (2016) 小児科診断・治療指針 17章 循環器疾患.先天性心疾患.大動脈縮窄・離断(複合)中山書店 (2016) 印刷中

5.檜垣高史 (2016) 心臓病児者の幸せのために 病気と制度の解説.第5章 大人になった先天性心疾患患者.心臓病者の就労.一般社団法人 全国心臓病の子どもを守る会 2016 印刷中

6.福田光成(2016)多発性硬化症.こどもの神経疾患の診かた.pp137-177

7.篠田邦大、田内久道(2016) 小児がん支持療法マニュアル.【総論】Ⅳ輸血 【各論】、ⅣDIC(播種性血管内凝固症候群)、ⅩⅥ 鼻出血の管理 pp27-31,pp72-74,pp108

8.平井洋生(2016)「小児・思春期1型糖尿病の診療ガイド」、「結婚、就職への対応」 南江堂,(in press)

9.楠目和代(2016)読者質問箱 小児の食物アレルギーと臨床検査について教えてください。「検査と技術」 医学書院 第45巻 第4号 ( in press)

10.大藤佳子(2016) 難病や障害をもつ子どもへのケアにおけるタクティールケアの可能性.はじめてのタクティールケア~手で“触れて”痛み・苦しみを緩和する~ 日本看護協会出版会 p22-28

愛媛大学小児科業績 2016

【総説】

1.石井榮一 (2016) ウイルス関連血球貪食症候群.免疫症候群(第2版).日本臨床社.Pp790-793

2.米澤早知子、石井榮一 (2016) 小児非ホジキンリンパ腫病期分類と効果判定の新基準.血液内科 72: 121-126

3.石井榮一 (2016) 血球貪食症候群.小児の症候群.小児科診療 194

4.Morimoto A, Nakazawa Y, Ishii E (2016) Hemophagocytic lymphohistiocytosis: pathogenesis, diagnosis, and management. Pediatr Int 58: 817-825

5.Ishii E (2016) Hemophagocytic Lymphohistiocytosis in Children: Pathogenesis and Treatment. Front Pediatr 2016 May 13; 4: 47.

6.子川和弘、古池雄治、石井榮一 (2016) 慢性疾患に伴う貧血(ACD).ACD と基礎疾患のかかわり 慢性感染症.日本臨床(印刷中)

7.Eguchi M, Eguchi-Ishimae M, Ishii E (2016) Hematopoietic stem cells: The basis of normal and malignant hematopoiesis. Hematological Disorders in Children – Pathogenesis and Treatment. Springer books. (in press)

8.江口真理子、石前峰斉、石井榮一 (2016) 小児白血病の発症過程 - 白血病幹細胞とclonal evolution – 、日本臨床74(8)、201-208

9.石前峰斉、江口真理子 (2016) 遺伝子プロファイリングと癌治療 – 白血病 -、癌と化学療法 43(11)、1341-1344

10.田内久道 (2016) 分子疫学的手法を用いた院内感染対策.愛媛医学 35:pp68-69

11.田内久道、安川正貴 (2016) 多剤耐性緑膿菌の治療.日本医事新報 4785:pp47

12.田内久道、安川正貴 (2016) 分子疫学的手法を用いた細菌感染経路の解析.日本医事新報 4791:pp51

13.田内久道、安川正貴 (2016) 質量分析装置を用いた細菌の同定検査.日本医事新報 4796:pp46

14.福田光成(2016)小児難聴診療の現状と今後の展望.愛媛医学.pp137-177

15.石田也寸志 (2016) 小児造血幹細胞移植後の晩期合併症とQOL. 日本造血細胞移植学会雑誌 5:51-63, 2016

16.石田也寸志 (2016) 造血幹細胞移植後の晩期合併症とQOL. 日本小児血液・がん学会雑誌 53,:231-238, 2016

17.石田也寸志 (2016) 血液腫瘍性疾患の移行期医療・支援. こどもケア 11:27-32

18.手束真理、石田也寸志 (2016) 小児白血病の疫学. 日本臨牀 74 119-126

19.苔口知樹, 神薗淳司, 市川光太郎 (2016) 呼吸数と心拍数測定における注意点と簡便な測定方法. 小児看護 39: 299-304

愛媛大学大学院医学系研究科分子・機能領域 小児科学講座

愛媛大学大学院  医学系研究科分子・機能領域  小児科学講座

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