運動器健康科学研究ユニットResearch Unit for Skeletal Health and Diseases

Outreach業績・報告

2020年度

Hiroshi Kiyomatsu, Jun Takeba, Hiroshi Imai, Takashi Inoue, Akihiko Jono, Kazunori Hino, Hiromasa Miura.
Treatment of osteochondritis dissecans of the humeral capitellum with a fragment fixation method using absorbable pins
Journal of Shoulder and Elbow Surgery . 2021 Mar.

William Halim Santoso, Momoko Ishida, Kosuke Nishi, Takuya Sugahara, Agus Budiawan Naro Putra.
Anti-allergy potential of Averrhoa bilimbi Linn. fruit water extract shown by its suppressive effect on the degranulation of RBL-2H3 cells.
Journal of Functional Food and Nutraceutical 2021 Feb. 2(2):81-88.

Toyama K, Igase M, Spin JM, Abe Y, Javkhlant A, Okada Y, Wagenhäuser MU, Schelzig H, Tsao PS, Mogi M.
Exosome miR-501-3p Elevation Contributes to Progression of Vascular Stiffness.
Circ Rep. 2021 Feb 17;3(3): 170-177. doi: 10.1253/circrep.CR-20-0135.

PubMed

Syaifullah AH, Shiino A, Fujiyoshi A, Kadota A, Kondo K, Ito T, Segawa H, Moniruzzaman M, Waki T, Miyagawa N, Tooyama I, Ueshima H, Miura K; SESSA Research Group; Co-chairpersons, Ueshima H, Miura K; Research members.
Alcohol drinking and brain morphometry in apparently healthy community-dwelling Japanese men.
Alcohol. 2021 Feb; 90: 57-65. doi: 10.1016/j.alcohol.2020.11.006. Epub 2020 Dec 3.

PubMed

Ueyama H, Ohta Y, Imai Y, Suzuki A, Sugama R, Minoda Y, Takaoka K, Nakamura H.
Topical co-administration of zoledronate with recombinant human bone morphogenetic protein-2 can induce and maintain bone formation in the bone marrow environment.
BMC Musculoskelet Disord. 2021 Jan 20;22(1):94. doi: 10.1186/s12891-021-03971-w.

PubMed

Akechi Y, Miura S, Ochi M, Enoki M, Matsuda T, Kitazawa R, Fujibuchi T, Ochi H, Igase M, Ohyagi Y.
Unilateral lower limb atrophy associated with glomus tumors: a case report.
J Med Case Rep. 2021 Jan 13;15: 8. doi: 10.1186/s13256-020-02616-1.

PubMed

Furukawa Y, Okuyama S, Amakura Y, Sawamoto A, Nakajima M, Yoshimura M, Igase M, Fukuda N, Tamai T, Yoshida T.
Isolation and Characterization of Neuroprotective Components from Citrus Peel and Their Application as Functional Food.
Chem Pharm Bull (Tokyo). 2021; 69: 2-10. doi: 10.1248/cpb.c20-00265.

PubMed

Kanou M, Nakamura K, Hrie K, Sakai H, Yanagihara Y, Sakakibara I, Yamana K, Imai Y.
AR ligand induces muscle anabolic effects by polyamine signaling through myofiber AR dependent and independent mechanism.
JCSM Rapid Commun. 2021 Jan;4(1):57-74. doi: 10.1002/rco2.28.

Iio H, Kikugawa T, Sawada Y, Sakai HYoshida SYanagihara YIkedo ASaeki N, Fukada S, Saika T, Imai Y.
DNA maintenance methylation enzyme Dnmt1 in satellite cells is essential for muscle regeneration
Biochem Biophys Res Commun. 2021 Jan 1;534:79-85. doi: 10.1016/j.bbrc.2020.11.116.

PubMed

Saeki N, Imai Y.
Reprogramming of synovial macrophage metabolism by synovial fibroblasts under inflammatory conditions
Cell Commun Signal. 2020 Nov 30;18(1):188. doi: 10.1186/s12964-020-00678-8.

PubMed

Miura S, Ochi M, Ochi H, Igase M, Kawaguchi N, Miyagawa M, Uchiyama Y, Ohyagi Y.
Bilateral parkinsonism in a patient with infarcts involving the unilateral basal ganglia.
eNeurological Sci. 2020 Nov 11; 21: 100291. doi: 10.1016/j.ensci.2020.100291.

PubMed

Nishihara E, Okada M, Kiyoi T, Shudou M, Imai Y, Hato N.
Evaluation of the structure of the otoconial layer using micro-computed tomography.
Auris Nasus Larynx. 2020 Oct;47(5):734-739. doi: 10.1016/j.anl.2020.02.013. Epub 2020 Mar 13.

PubMed

Igase M, Okada Y, Igase K, Matsumoto S, Senzaki K, Ochi M, Ohyagi Y, Yamagishi SI.
Casein Hydrolysate Containing Milk-Derived Peptides Reduces Facial Pigmentation Partly by Decreasing Advanced Glycation End Products in the Skin: A Randomized Double-Blind Placebo-Controlled Trial.
Rejuvenation Res. 2020 Sep 22. doi: 10.1089/rej.2020.2343. Online ahead of print.

PubMed

Nakanishi Y, Nakashima Y, Fujiwara Y, Komohara Y, Hino K, Miura H, Higaki H.
Microfluidic device used for the secretion of inflammatory cytokines from human monocyte-derived macrophages stimulated by ultra-high molecular weight polyethylene particles.
Biotribol 2020 Sep. 23:100137

Kiel DP, Kemp JP, Rivadeneira F, Westendorf JJ, Karasik D, Duncan E, Imai Y, Müller R, Flannick J, Bonewald L, Burtt N.
The Musculoskeletal Knowledge Portal: Making Omics Data Useful to the Broader Scientific Community
J Bone Miner Res. 2020 Sep;35(9):1626-1633. doi: 10.1002/jbmr.4147.

PubMed

Seko D, Fujita R, Kitajima Y, Nakamura K, Imai Y, Ono Y.
Estrogen receptor β controls muscle growth and regeneration in young female mice
Stem Cell Reports. 2020 Sep 8;15(3):577-586. doi: 10.1016/j.stemcr.2020.07.017.  Epub 2020 Aug 20.

Misaki H, Morino T, Hino M, Murakami Y, Imai H, Miura H.
Can diffuse idiopathic skeletal hyperostosis be diagnosed by plain lumbar spine x-ray findings alone?
Global Spine J. 2020 Aug 17. doi: 10.1177/2192568220948038.

Sakai H, Sato T, Kanagawa M, Fukada S, Imai Y.
Androgen receptor in satellite cells is not essential for muscle regenerations
Experimental Results. 2020 July 29. 1, e21, 1-9. doi:10.1017/exp.2020.14.

Satoshi Yamauchi, Asuka Nishimoto, Hisashi Nishiwaki, Kosuke Nishi, Takuya Sugahara.
Discovery of stereospecific cytotoxicity of (8R,8′R)-trans-arctigenin against insect cells and structure-activity relationship on aromatic ring.
Bioorganic and Medicinal Chemistry Letters. 2020 Jul 1; 30(13):127191

PubMed

Adhikari S, Bhattarai K, Abe Y, Kira M, Fujitani M, Miyada T, Kishida T.
Dietary daidzein decreases food intake accompanied with delayed gastric emptying in ovariectomized rats
Biosci Biotechnol Biochem. 2020 Jun;84(6):1232-1238.

PubMed

Imai H, Kamada T, Miyawaki J, Maruishi A, Mashima N, Miura H.
Outcomes of computerassisted periacetabular osteotomy compared with conventional osteotomy in hip dysplasia.
Int Orthop 2020 Jun; 44:1055-1061.

PubMed

Spracklen CN, Horikoshi M, Kim YJ, Lin K, Bragg F, Moon S, Suzuki K, Tam CHT, Tabara Y, Kwak SH, Takeuchi F, Long J, Lim VJY, Chai JF, Chen CH, Nakatochi M, Yao J, Choi HS, Iyengar AK, Perrin HJ, Brotman SM, van de Bunt M, Gloyn AL, Below JE, Boehnke M, Bowden DW, Chambers JC, Mahajan A, McCarthy MI, Ng MCY, Petty LE, Zhang W, Morris AP, Adair LS, Akiyama M, Bian Z, Chan JCN, Chang LC, Chee ML, Chen YI, Chen YT, Chen Z, Chuang LM, Du S, Gordon-Larsen P, Gross M, Guo X, Guo Y, Han S, Howard AG, Huang W, Hung YJ, Hwang MY, Hwu CM, Ichihara S, Isono M, Jang HM, Jiang G, Jonas JB, Kamatani Y, Katsuya T, Kawaguchi T, Khor CC, Kohara K, Lee MS, Lee NR, Li L, Liu J, Luk AO, Lv J, Okada Y, Pereira MA, Sabanayagam C, Shi J, Shin DM, So WY, Takahashi A, Tomlinson B, Tsai FJ, van Dam RM, Xiang YB, Yamamoto K, Yamauchi T, Yoon K, Yu C, Yuan JM, Zhang L, Zheng W, Igase M, Cho YS, Rotter JI, Wang YX, Sheu WHH, Yokota M, Wu JY, Cheng CY, Wong TY, Shu XO, Kato N, Park KS, Tai ES, Matsuda F, Koh WP, Ma RCW, Maeda S, Millwood IY, Lee J, Kadowaki T, Walters RG, Kim BJ, Mohlke KL, Sim X.
Identification of type 2 diabetes loci in 433,540 East Asian individuals.
Nature. 2020 Jun; 582: 240-245. doi: 10.1038/s41586-020-2263-3.

PubMed

Satoshi Okano, Masayuki Mori, Sengo Kobayashi, Takeaki Okamoto.
Nanotube formation on Ti-15Zr-4Nb-4Ta by anodic oxidation
Materials Science Forum. 2020 Apr ; 985,69-73

Kenta Nisogi, Satoshi Okano, Sengo Kobayashi, Kensuke Kuroda, Takeaki Okamoto.
Effects of Titanium Surface Wettability on Osteoblast Behavior in Vitro
Materials Science Forum. 2020 Apr; 985:64-68

Kohara Y, Haraguchi R, Kitazawa R, Imai Y, Kitazawa S.
Hedgehog Inhibitors Suppress Osteoclastogenesis in In Vitro Cultures, and Deletion of Smo in Macrophage/Osteoclast Lineage Prevents Age-Related Bone Loss
Int. J. Mol. Sci. 2020 Apr 15;21(8):2745. doi: 10.3390/ijms21082745.

PubMed

Kosuke Nishi, Mizuki Mori, Daisuke Nakayama, Junna Sato, In-Hae Kim, Minju Kim, Songmun Kim, Takuya Sugahara.
Anti-melanogenic activity of methanolic extract from leaves of Sorbaria sorbifolia var. stellipila Max. on α-MSH-stimulated B16 melanoma 4A5 cells.
Biomedical Dermatology. 2020 Apr 15;4(7). doi: 10.1186/s41702-020-0061-z

Murakami Y, Morino T, Masayuki H, Misaki H, Miura H.
Progression of ossification of the anterior longitudinal ligament associated with diffuse idiopathic skeletal hyperostosis by age.
Global Spine J. 2020 Apr 13; 2192568220918817. doi: 10.1177/2192568220918817.

PubMed

Tabara Y, Kohara K, Okada Y, Ohyagi Y, Igase M.
Creatinine to Cystatin C Ratio as a Marker of Bone Property in Older Adults: The J-SHIPP Study.
J Nutr Health Aging. 2020; 24: 277-281. doi: 10.1007/s12603-020-1315-6.

PubMed

Ohta Y, Kamide K, Hanada H, Morimoto S, Nakahashi T, Takiuchi S, Ishimitsu T, Tsuchihashi T, Soma M, Tomohiro Katsuya T, Sugimoto K, Rakugi H, Oukura T, Higaki J, Matsuura H, Shinagawa T, Miwa Y, Sasaguri T, Igase M, Miki T, Takeda K, Higashiura K, Shimamoto K, Katabuchi R, Ueno M, Hosomi N, Kato J, Komai N, Kojima S, Sase K, Iwashima Y, Yoshihara F, Horio T, Nakamura S, Nakahama H, Miyata T, Kawano Y.
Genetic factors associated with elevation of uric acid after treatment with thiazide-like diuretic in patients with essential hypertension.
Hypertens Res. 2020; 43: 220-226. doi: 10.1038/s41440-019-0356-x.

PubMed

Fujibuchi T, Miyawaki J, Kidani T, Imai H, Miura H.
Prediction of soft tissue sarcoma from clinical characteristics and laboratory data.
Cancers (Basel)  2020; 12: 679

PubMed

西甲介
Docosahexaenoyl ethanolamideのIgE依存性アレルギー反応への影響
臨床免疫・アレルギー科 74(1):39-43, 2020年7月

清松 悠, 日野 和典, 三浦 裕正, 大嶋 佑介
ラマン分光法による軟骨評価と診断治療への応用
日本関節病学会誌  2020 39 巻 2 号     p. 91-97

西甲介
スパイス・ハーブの機能と応用
第4章 双子葉植物 9 セリ科(クミン,コリアンダー)
シーエムシー出版, 2020年10月

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