2015年度 業績・研究成果 (分子医療部門)
2017.01.27
原著論文
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Low protein diet-induced fetal growth restriction leads to exaggerated proliferative response to vascular injury in postnatal life. Chisaka T, Mogi M, Nakaoka H, Kan-no H, Tsukuda K, Wang XL, Bai HY, Shan BS, Kukida M, Iwanami J, Higaki T, Ishii E, Horiuchi M. Am J Hypertens. 2016 Jan;29(1):54-62.
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Glucose transporter 1-positive endothelial cells in infantile hemangioma exhibit features of facultative stem cells. Huang L, Nakayama H, Klagsbrun M, Mulliken JB, Bischoff J. Stem Cells. 2015 Jan;33(1):133-45.
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High-throughput synthesis of stable isotope-labeled transmembrane proteins for targeted transmembrane proteomics using a wheat germ cell-free protein synthesis system. Takemori N, Takemori A, Matsuoka K, Morishita R, Matsushita N, Aoshima M, Takeda H, Sawasaki T, Endo Y, Higashiyama S. Mol Biosyst. 2015 Feb;11(2):361-5.
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Reversible interconversion and maintenance of mammary epithelial cell characteristics by the ligand-regulated EGFR system. Fukuda S, Nishida-Fukuda H, Nanba D, Nakashiro K, Nakayama H, Kubota H, Higashiyama S. Sci Rep. 2016 Feb 2;6:20209.
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Direct angiotensin II type 2 receptor stimulation by compound 21 prevents vascular dementia. Iwanami J, Mogi M, Tsukuda K, Wang XL, Nakaoka H, Kan-No H, Chisaka T, Bai HY, Shan BS, Kukida M, Horiuchi M. J Am Soc Hypertens, 2015 Apr 9(4): 250-256.
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Cell motion predicts human epidermal stemness. Nanba D, Toki F, Tate S, Imai M, Matsushita N, Shiraishi K, Sayama K, Toki H, Higashiyama S, Barrandon Y. J Cell Biol. 2015 Apr 27;209(2):305-15.
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Long‑term exposure to leptin enhances the growth of prostate cancer cells. Noda T, Kikugawa T, Tanji N, Miura N, Asai S, Higashiyama S, Yokoyama M. Int J Oncol. 2015 Apr;46(4):1535-42.
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Complementary probes reveal that phosphatidylserine is required for the proper transbilayer distribution of cholesterol. Maekawa M, Fairn GD. J Cell Sci. 2015 Apr 1;128(7):1422-33. doi: 10.1242/jcs.164715.
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Regulation of mTOR Signaling by Semaphorin 3F-Neuropilin 2 Interactions In Vitro and In Vivo. Nakayama H, Bruneau S, Kochupurakkal N, Coma S, Briscoe DM, Klagsbrun M. Sci Rep. 2015 Jul 9;5:11789.
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The GPR 55 agonist, L-α-lysophosphatidylinositol, mediates ovarian carcinoma cell-induced angiogenesis. Hofmann NA, Yang J, Trauger SA, Nakayama H, Huang L, Strunk D, Moses MA, Klagsbrun M, Bischoff J, Graier WF. Br J Pharmacol. 2015 Aug;172(16):4107-18.
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Infantile hemangioma-derived stem cells and endothelial cells are inhibited by class 3 semaphorins. Nakayama H, Huang L, Kelly RP, Oudenaarden CR, Dagher A, Hofmann NA, Moses MA, Bischoff J, Klagsbrun M. Biochem Biophys Res Commun. 2015 Aug 14;464(1):126-32.
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Pre-treatment with LCZ696, an orally active angiotensin receptor neprilysin inhibitor, prevents ischemic brain damage. Bai HY, Mogi M, Nakaoka H, Kan-no H, Tsukuda K, Chisaka T, Wang XL, Kukida M, Shan BS, Kukida M, Yamauchi T, Higaku A, Iwanami J, Horiuchi M. Eur J Pharmacol. 2015 Sep 5;762:293-8.
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Does chronic hypertension prevent cancer progression? Mogi M, Horiuchi M. Hypertens Res. 2015 Nov;38(11):711-2.
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Rotation is the primary motion of paired human epidermal keratinocytes. Tate S, Imai M, Matsushita N, Nishimura EK, Higashiyama S, Nanba D. J Dermatol Sci. 2015 Sep;79(3):194-202.
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Platelet-endothelial cell interaction in brain microvessels of angiotensin II type-2 receptor knockout mice following transient bilateral common caroyid artery occlusion. Fukuoka T, Hayashi T, Hirayama M, Maruyama H, Mogi M, Horiuchi M, Takao M, Tanahashi N. J Thromb Thrombolysis. 2015 Nov;40(4):401-5.
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Inhibition of Acid Sphingomyelinase Depletes Cellular Phosphatidylserine and Mislocalizes K-Ras from the Plasma Membrane. Cho KJ, van der Hoeven D, Zhou Y, Maekawa M, Ma X, Chen W, Fairn GD, Hancock JF. Mol Cell Biol. 2015 Nov 16;36(2):363-74
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Angiotensin II type 2 receptor signaling affects dopamine levels in the brain and prevents binge eating disorder. Nakaoka H, Mogi M, Kan-no H, Tsukuda K, Ohshima K, Wang XL, Chisaka T, Bai HY, Shan BS, Kukida M, Iwanami J, Horiuchi M. J Renin Angiotensin Aldosterone Syst. 2015 Dec;16(4):749-57.
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Role of the Renal Sympathetic nerve in renal glucose metabolism during the development of type 2 diabetes in rats. Rafiq K, Fujisawa Y, Sherajee SJ, Rahman A, Sufiun A, Kobori H, Koepsell H, Mogi M, Horiuchi M, Nishiyama A. Diabetologia. 2015 Dec;58(12):2885-98.
国内及び国際学会での招待講演
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Horiuchi M,Roles of angiotensin II type 2 receptor in cognitive function,第38回日本高血圧学会総会(2015年10月9日~10月11日,ひめぎんホール、愛媛)
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Horiuchi M,私とレニン・アンジオテンシン系,第38回日本高血圧学会総会(2015年10月9日~10月11日,ひめぎんホール、愛媛)
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Horiuchi M,Stroke, Cognitive Function and Renin Angiotensin System,11th Asia Pacific Congress of Hypertension 2015(Bali, Indonesia,June 4-7, 2015)
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Horiuchi M,Vascular Remodeling: Roles of Protective Arm of Renin Angiotensin System,11th Asia Pacific Congress of Hypertension 2015(Bali, Indonesia,June 4-7, 2015)
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堀内正嗣,レニン・アンジオテンシン系Protective Armと血管保護,第4回臨床高血圧フォーラム(アクロス福岡、福岡,2015年5月23日~5月24日)
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茂木正樹,JSH2014:学会アンケート調査より見えるもの,第4回臨床高血圧フォーラム(アクロス福岡、福岡,2015年5月23日~5月24日)
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茂木正樹,脳のアンチエイジング –Next Decade-,第15回日本抗加齢医学会総会,若手研究者プログラムセッション「アンチエイジングのNext Decade」(福岡国際会議場、福岡,2015年5月29日)
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茂木正樹,認知症と高血圧,第34回日本認知症学会学術集会,シンポジウム2「生活習慣病と認知症」(ホテル青森あすなろ、青森,2015年10月2日)
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Masaki Mogi,Neuroinflammation and Hypertension,38th Annual Scientific Meeting of the Japanese Society of Hypertension(Himegin-Hall, Ehime,Oct 9, 2015)
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Masaki Mogi,China-Japan-Koria Joint Symposium,38th Annual Scientific Meeting of the Japanese Society of Hypertension(Himegin-Hall, Ehime,Oct 9, 2015)