研究業績

1          Shimokawa, T., Nabeka, H., Khan, S. I., Yamamiya, K., Doihara, T., Kobayashi, N., Wakisaka, H. & Matsuda, S. Prosaposin in the rat oviductal epithelial cells. Cell and Tissue Research 383, 1191-1202, doi:10.1007/s00441-020-03339-x (2021).

2          Sarkar, S., Homma, T., Onouchi, S., Shimizu, Y., Shiina, T., Nabeka, H., Matsuda, S. & Saito, S. Expression of the G protein-coupled receptor (GPR) 37 and GPR37L1 in the mouse digestive system. Journal of Veterinary Medical Science 83, 1-8, doi:10.1292/jvms.20-0603 (2021).

3          Takeuchi, A., Takahashi, Y., Iida, K., Hosokawa, M., Irie, K., Ito, M., Brown, J. B., Ohno, K., Nakashima, K. & Hagiwara, M. Identification of Qk as a Glial Precursor Cell Marker that Governs the Fate Specification of Neural Stem Cells to a Glial Cell Lineage. Stem Cell Reports 15, 883-897, doi:10.1016/j.stemcr.2020.08.010 (2020).

4          Kunihiro, J., Nabeka, H., Wakisaka, H., Unuma, K., Khan, M. S. I., Shimokawa, T., Islam, F., Doihara, T., Yamamiya, K., Saito, S., Hamada, F. & Matsuda, S. Prosaposin and its receptors GRP37 and GPR37L1 show increased immunoreactivity in the facial nucleus following facial nerve transection. PLoS One 15, e0241315, doi:10.1371/journal.pone.0241315 (2020).

5          Khan, M. S. I., Nabeka, H., Akbar, S. M. F., Al Mahtab, M., Shimokawa, T., Islam, F. & Matsuda, S. Risk of congenital birth defects during COVID-19 pandemic: Draw attention to the physicians and policymakers. J Glob Health 10, 020378, doi:10.7189/jogh.10.020378 (2020).

6          Khan, M. S. I., Khan, M. S. I., Debnath, C. R., Nath, P. N., Mahtab, M. A., Nabeka, H., Matsuda, S. & Akbar, S. M. F. Ivermectin Treatment May Improve the Prognosis of Patients With COVID-19. Arch Bronconeumol 56, 828-830, doi:10.1016/j.arbres.2020.08.007 (2020).

7          Khan, M. S., Nabeka, H., Islam, F., Shimokawa, T., Saito, S., Tachibana, T. & Matsuda, S. Suppression of GABAergic transmission in the spinal dorsal horn induces pain-related behaviour in a chicken model of spina bifida. Folia Neuropathol 58, 151-165, doi:10.5114/fn.2020.96800 (2020).

8          Islam, F., Khan, M. S. I., Nabeka, H., Shimokawa, T., Yamamiya, K. & Matsuda, S. Age- and sex-associated changes in prosaposin and its receptors in the lacrimal glands of rats. Histol Histopathol 35, 69-81, doi:10.14670/hh-18-137 (2020).

9          Iida, K., Hagiwara, M. & Takeuchi, A. Multilateral Bioinformatics Analyses Reveal the Function-Oriented Target Specificities and Recognition of the RNA-Binding Protein SFPQ. iScience 23, 101325, doi:10.1016/j.isci.2020.101325 (2020).

10        Yamamiya K., L. X., Nabeka H., Shimokawa T., Khan M.S.I., Doihara T., Saito S., Hamada F., Matsuda S., Kobayashi N. Function of prosaposin in the testis. The 124th Annual Meeting of the Japanese Association of Anatomists, 176 (2019).

11        Kurokawa, R., Takeuchi, A., Shiina, N., Katahira, M., Yamashita, T., Matsuno, Y., Hitachi, K., Ishigaki, S., Haamad, N., Yoneda, R., Ueda, N., Iida, K., Hosokawa, M., Hagiwara, M., Iida, M., Mashima, T., Yamaoki, Y., So, M., Nagata, T., Sobue, G., Kondo, K., Watanabe, H. & Uchihashi, T. Versatility of RNA-Binding Proteins in Living Cells. Biomedical Sciences 5, 7-13, doi:10.11648/j.bs.20190501.12 (2019).

12        Hosokawa, M., Takeuchi, A., Tanihata, J., Iida, K., Takeda, S. & Hagiwara, M. Loss of RNA-Binding Protein Sfpq Causes Long-Gene Transcriptopathy in Skeletal Muscle and Severe Muscle Mass Reduction with Metabolic Myopathy. iScience 13, 229-242, doi:10.1016/j.isci.2019.02.023 (2019).

13        Takeuchi, A., Iida, K., Tsubota, T., Hosokawa, M., Denawa, M., Brown, J. B., Ninomiya, K., Ito, M., Kimura, H., Abe, T., Kiyonari, H., Ohno, K. & Hagiwara, M. Loss of Sfpq Causes Long-Gene Transcriptopathy in the Brain. Cell Rep 23, 1326-1341, doi:10.1016/j.celrep.2018.03.141 (2018).

14        Islam, F., Khan, M. S. I., Nabeka, H., Saito, S., Li, X., Shimokawa, T., Yamamiya, K., Kobayashi, N. & Matsuda, S. Prosaposin and its receptors are differentially expressed in the salivary glands of male and female rats. Cell and Tissue Research 373, 439-457, doi:10.1007/s00441-018-2835-9 (2018).

15        Nabeka, H., Saito, S., Li, X., Shimokawa, T., Khan, M. S. I., Yamamiya, K., Kawabe, S., Doihara, T., Hamada, F., Kobayashi, N. & Matsuda, S. Interneurons secrete prosaposin, a neurotrophic factor, to attenuate kainic acid-induced neurotoxicity. IBRO Reports 3, 17-32, doi:https://doi.org/10.1016/j.ibror.2017.07.001 (2017).

16        Li, X., Nabeka, H., Saito, S., Shimokawa, T., Khan, M. S. I., Yamamiya, K., Shan, F., Gao, H., Li, C. & Matsuda, S. Expression of prosaposin and its receptors in the rat cerebellum after kainic acid injection. IBRO Rep 2, 31-40, doi:10.1016/j.ibror.2017.02.002 (2017).

17        Khan, M. S. I., Nabeka, H., Islam, F., Shimokawa, T., Saito, S., Li, X., Kawabe, S., Hamada, F., Tachibana, T. & Matsuda, S. Early neonatal loss of inhibitory synaptic input to the spinal motor neurons confers spina bifida-like leg dysfunction in a chicken model. Dis Model Mech10, 1421-1432, doi:10.1242/dmm.031054 (2017).

18        Gao, H. L., Li, C., Nabeka, H., Shimokawa, T., Wang, Z. Y., Cao, Y. M. & Matsuda, S. An 18-mer Peptide Derived from Prosaposin Ameliorates the Effects of Aβ1-42 Neurotoxicity on Hippocampal Neurogenesis and Memory Deficit in Mice. J Alzheimers Dis 53, 1173-1192, doi:10.3233/jad-160093 (2016).

19        Yoshida, M., Kataoka, N., Miyauchi, K., Ohe, K., Iida, K., Yoshida, S., Nojima, T., Okuno, Y., Onogi, H., Usui, T., Takeuchi, A., Hosoya, T., Suzuki, T. & Hagiwara, M. Rectifier of aberrant mRNA splicing recovers tRNA modification in familial dysautonomia. Proceedings of the National Academy of Sciences, USA 112, 2764-2769, doi:10.1073/pnas.1415525112 (2015).

20        Ohnishi, T., Yanazawa, M., Sasahara, T., Kitamura, Y., Hiroaki, H., Fukazawa, Y., Kii, I., Nishiyama, T., Kakita, A., Takeda, H., Takeuchi, A., Arai, Y., Ito, A., Komura, H., Hirao, H., Satomura, K., Inoue, M., Muramatsu, S., Matsui, K., Tada, M., Sato, M., Saijo, E., Shigemitsu, Y., Sakai, S., Umetsu, Y., Goda, N., Takino, N., Takahashi, H., Hagiwara, M., Sawasaki, T., Iwasaki, G., Nakamura, Y., Nabeshima, Y., Teplow, D. B. & Hoshi, M. Na, K-ATPase alpha3 is a death target of Alzheimer patient amyloid-beta assembly. Proceedings of the National Academy of Sciences, USA 112, E4465-4474, doi:10.1073/pnas.1421182112 (2015).

21        Nabeka, H., Shimokawa, T., Doihara, T., Saito, S., Wakisaka, H., Hamada, F., Kobayashi, N. & Matsuda, S. A prosaposin-derived Peptide alleviates kainic Acid-induced brain injury. PLoS One 10, e0126856, doi:10.1371/journal.pone.0126856 (2015).

22        Saito, S., Saito, K., Nabeka, H., Shimokawa, T., Kobayashi, N. & Matsuda, S. Differential expression of the alternatively spliced forms of prosaposin mRNAs in rat choroid plexus. Cell and Tissue Research 356, 231-242, doi:10.1007/s00441-013-1773-9 (2014).

23        Nabeka, H., Uematsu, K., Takechi, H., Shimokawa, T., Yamamiya, K., Li, C., Doihara, T., Saito, S., Kobayashi, N. & Matsuda, S. Prosaposin Overexpression following Kainic Acid-Induced Neurotoxicity. PLoS One 9, e110534, doi:10.1371/journal.pone.0110534 (2014).

24        Morishita, M., Nabeka, H., Shimokawa, T., Miyawaki, K., Doihara, T., Saito, S., Kobayashi, N. & Matsuda, S. Temporal changes in prosaposin expression in the rat dentate gyrus after birth. PLoS One 9, e95883, doi:10.1371/journal.pone.0095883 (2014).

25        Terashita, T., Saito, S., Nabeka, H., Hato, N., Wakisaka, H., Shimokawa, T., Kobayashi, N., Gyo, K. & Matsuda, S. Prosaposin-derived peptide alleviates ischaemia-induced hearing loss. Acta Otolaryngol 133, 462-468, doi:10.3109/00016489.2012.750430 (2013).

26        Shimokawa, T., Nabeka, H., Yamamiya, K., Wakisaka, H., Takeuchi, T., Kobayashi, N. & Matsuda, S. Distribution of prosaposin in rat lymphatic tissues. Cell and Tissue Research 352, 685-693, doi:10.1007/s00441-013-1575-0 (2013).

27        Li, C., Gao, H. L., Shimokawa, T., Nabeka, H., Hamada, F., Araki, H., Cao, Y. M., Kobayashi, N. & Matsuda, S. Prosaposin expression in the regenerated muscles of mdx and cardiotoxin-treated mice. Histol Histopathol 28, 875-892, doi:10.14670/hh-28.875 (2013).

28        Gao, H. L., Li, C., Nabeka, H., Shimokawa, T., Saito, S., Wang, Z. Y., Cao, Y. M. & Matsuda, S. Attenuation of MPTP/MPP(+) toxicity in vivo and in vitro by an 18-mer peptide derived from prosaposin. Neuroscience 236, 373-393, doi:10.1016/j.neuroscience.2013.01.007 (2013).

29        Gao, H. L., Li, C., Nabeka, H., Shimokawa, T., Kobayashi, N., Saito, S., Wang, Z. Y., Cao, Y. M. & Matsuda, S. Decrease in prosaposin in the Dystrophic mdx mouse brain. PLoS One 8, e80032, doi:10.1371/journal.pone.0080032 (2013).

30        Shimokawa, T., Doihara, T., Makara, M., Miyawaki, K., Nabeka, H., Wakisaka, H., Kobayashi, N. & Matsuda, S. Lectin binding pattern of gastric mucosa of pacific white-sided dolphin, Lagenorhynchus obliquidens. Journal of Veterinary Medical Science 74, 155-160, doi:10.1292/jvms.11-0115 (2012).

31        Zhang, X., Li, C., Gao, H., Nabeka, H., Shimokawa, T., Wakisaka, H., Matsuda, S. & Kobayashi, N. Rho kinase inhibitors stimulate the migration of human cultured osteoblastic cells by regulating actomyosin activity. Cellular & Molecular Biology Letters 16, 279-295, doi:10.2478/s11658-011-0006-z (2011).

32        Xue, B., Chen, J., Gao, H., Saito, S., Kobayashi, N., Shimokawa, T., Nabeka, H., Sano, A. & Matsuda, S. Chronological changes in prosaposin in the developing rat brain. Neurosci Res 71, 22-34, doi:10.1016/j.neures.2011.06.001 (2011).

33        Wang, M., Mominoki, K., Kinutani, M., Wang, Z., Kobayashi, N., Shimokawa, T., Nabeka, H., Fujiwara, T. & Matsuda, S. Developmental delay in islet-1-positive motor neurons in chick spina bifida. Journal of Veterinary Medical Science 73, 447-452, doi:10.1292/jvms.10-0385 (2011).

34        Tsujimura, R., Mominoki, K., Kinutani, M., Shimokawa, T., Doihara, T., Nabeka, H., Wakisaka, H., Kobayashi, N. & Matsuda, S. Sensory tract abnormality in the chick model of spina bifida. Neurosci Res 71, 85-91, doi:10.1016/j.neures.2011.05.017 (2011).

35        Sims-Lucas, S., Cusack, B., Baust, J., Eswarakumar, V. P., Masatoshi, H., Takeuchi, A. & Bates, C. M. Fgfr1 and the IIIc isoform of Fgfr2 play critical roles in the metanephric mesenchyme mediating early inductive events in kidney development. Developmental Dynamics 240, 240-249, doi:10.1002/dvdy.22501 (2011).

36        Shimokawa, T., Doihara, T., Makara, M., Miyawaki, K., Nabeka, H., Wakisaka, H., Kobayashi, N. & Matsuda, S. Lectin histochemistry of respiratory mucosa in the Pacific white-sided dolphin. Journal of Veterinary Medical Science 73, 1233-1236, doi:10.1292/jvms.11-0116 (2011).

37        Takeuchi, A., Hosokawa, M., Nojima, T. & Hagiwara, M. Splicing reporter mice revealed the evolutionally conserved switching mechanism of tissue-specific alternative exon selection. PLoS One 5, e10946, doi:10.1371/journal.pone.0010946 (2010).

38        Chen, J., Saito, S., Kobayashi, N., Sato, K., Terashita, T., Shimokawa, T., Mominoki, K., Miyawaki, K., Sano, A. & Matsuda, S. Expression patterns in alternative splicing forms of prosaposin mRNA in the rat facial nerve nucleus after facial nerve transection. Neurosci Res 60, 82-94, doi:10.1016/j.neures.2007.09.010 (2008).

39        Tsujimura, R., Nabeka, H., Terashita, T., Shimokawa, T., Matsuda, S. & Kobayashi, N. A double aortic arch with a deformed trachea accompanied by a subaortic left innominate vein. Ann Anat 189, 197-201, doi:10.1016/j.aanat.2006.07.010 (2007).

40        Terashita, T., Saito, S., Miyawaki, K., Hyodo, M., Kobayashi, N., Shimokawa, T., Saito, K., Matsuda, S. & Gyo, K. Localization of prosaposin in rat cochlea. Neurosci Res 57, 372-378, doi:10.1016/j.neures.2006.11.006 (2007).

41        Takeuchi, A., Hamasaki, T., Litwack, E. D. & O'Leary, D. D. Novel IgCAM, MDGA1, expressed in unique cortical area- and layer-specific patterns and transiently by distinct forebrain populations of Cajal-Retzius neurons. Cerebral Cortex 17, 1531-1541, doi:bhl064 [pii]

10.1093/cercor/bhl064 (2007).

42        O'Leary, D. D., Chou, S. J., Hamasaki, T., Sahara, S., Takeuchi, A., Thuret, S. & Leingartner, A. Regulation of laminar and area patterning of mammalian neocortex and behavioural implications. Novartis Foundation Symposium 288, 141-159; discussion 159-164, 276-181 (2007).

43        Hosoda, Y., Miyawaki, K., Saito, S., Chen, J., Bing, X., Terashita, T., Kobayashi, N., Araki, N., Shimokawa, T., Hamada, F., Sano, A., Tanabe, H. & Matsuda, S. Distribution of prosaposin in the rat nervous system. Cell and Tissue Research 330, 197-207, doi:10.1007/s00441-007-0464-9 (2007).

44        Takeuchi, A. & O'Leary, D. D. Radial migration of superficial layer cortical neurons controlled by novel Ig cell adhesion molecule MDGA1. Journal of Neuroscience 26, 4460-4464, doi:26/17/4460 [pii]

10.1523/JNEUROSCI.4935-05.2006 (2006).

45        Takeuchi, A., Mishina, Y., Miyaishi, O., Kojima, E., Hasegawa, T. & Isobe, K. Heterozygosity with respect to Zfp148 causes complete loss of fetal germ cells during mouse embryogenesis. Nature Genetics 33, 172-176, doi:10.1038/ng1072

ng1072 [pii] (2003).

46        Kojima, E., Takeuchi, A., Haneda, M., Yagi, A., Hasegawa, T., Yamaki, K., Takeda, K., Akira, S., Shimokata, K. & Isobe, K. The function of GADD34 is a recovery from a shutoff of protein synthesis induced by ER stress: elucidation by GADD34-deficient mice. FASEB Journal 17, 1573-1575, doi:10.1096/fj.02-1184fje

02-1184fje [pii] (2003).

47        Takeuchi, A., Miyaishi, O., Kiuchi, K. & Isobe, K. Macrophage colony-stimulating factor is expressed in neuron and microglia after focal brain injury. Journal of Neuroscience Research 65, 38-44 (2001).

48        Takeuchi, A., Miyaishi, O., Kiuchi, K. & Isobe, K. Cu/Zn- and Mn-superoxide dismutases are specifically up-regulated in neurons after focal brain injury. Journal of Neurobiology 45, 39-46, doi:10.1002/1097-4695(200010)45:1<39::AID-NEU4>3.0.CO;2-A [pii] (2000).

49        Hasegawa, T., Takeuchi, A., Miyaishi, O., Xiao, H., Mao, J. & Isobe, K. PTRF (polymerase I and transcript-release factor) is tissue-specific and interacts with the BFCOL1 (binding factor of a type-I collagen promoter) zinc-finger transcription factor which binds to the two mouse type-I collagen gene promoters. Biochemical Journal 347 Pt 1, 55-59 (2000).

50        Maehara, K., Hasegawa, T., Xiao, H., Takeuchi, A., Abe, R. & Isobe, K. Cooperative interaction of NF-kappaB and C/EBP binding sites is necessary for manganese superoxide dismutase gene transcription mediated by lipopolysaccharide and interferon-gamma. FEBS Letters 449, 115-119, doi:S0014579399004081 [pii] (1999).

51        Takeuchi, A., Isobe, K. I., Miyaishi, O., Sawada, M., Fan, Z. H., Nakashima, I. & Kiuchi, K. Microglial NO induces delayed neuronal death following acute injury in the striatum. European Journal of Neuroscience 10, 1613-1620 (1998).

52        Yamada, E., Ishiguro, N., Miyaishi, O., Takeuchi, A., Nakashima, I., Iwata, H. & Isobe, K. Differential display analysis of murine collagen-induced arthritis: cloning of the cDNA-encoding murine ATPase inhibitor. Immunology 92, 571-576 (1997).

53        Nozaki, Y., Hasegawa, Y., Takeuchi, A., Fan, Z. H., Isobe, K. I., Nakashima, I. & Shimokata, K. Nitric oxide as an inflammatory mediator of radiation pneumonitis in rats. American Journal of Physiology: Lung Cellular and Molecular Physiology 272, L651-658 (1997).

54        Hasegawa, T., Takeuchi, A., Miyaishi, O., Isobe, K. & de Crombrugghe, B. Cloning and characterization of a transcription factor that binds to the proximal promoters of the two mouse type I collagen genes. Journal of Biological Chemistry 272, 4915-4923 (1997).

55        Aono, K., Isobe, K., Kiuchi, K., Fan, Z. H., Ito, M., Takeuchi, A., Miyachi, M., Nakashima, I. & Nimura, Y. In vitro and in vivo expression of inducible nitric oxide synthase during experimental endotoxemia: involvement of other cytokines. Journal of Cellular Biochemistry 65, 349-358, doi:10.1002/(SICI)1097-4644(19970601)65:3<349::AID-JCB5>3.0.CO;2-S [pii] (1997).